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Items: 1 to 50 of 130

1.

Vitamin B3 in Health and Disease: Toward the Second Century of Discovery.

Jacobson MK, Jacobson EL.

Methods Mol Biol. 2018;1813:3-8. doi: 10.1007/978-1-4939-8588-3_1. Review.

PMID:
30097857
2.

Antonovsky's Sense of Coherence Scale: Cultural Validation of Soc Questionnaire and Socio-Demographic Patterns in an Italian Population.

Sardu C, Mereu A, Sotgiu A, Andrissi L, Jacobson MK, Contu P.

Clin Pract Epidemiol Ment Health. 2012;8:1-6. doi: 10.2174/1745017901208010001. Epub 2012 Feb 14.

3.

Folate in skin cancer prevention.

Williams JD, Jacobson EL, Kim H, Kim M, Jacobson MK.

Subcell Biochem. 2012;56:181-97. doi: 10.1007/978-94-007-2199-9_10. Review.

4.

Niacin: vitamin and antidyslipidemic drug.

Jacobson EL, Kim H, Kim M, Jacobson MK.

Subcell Biochem. 2012;56:37-47. doi: 10.1007/978-94-007-2199-9_3. Review.

PMID:
22116693
5.

Quantification of poly(ADP-ribose) in vitro: determination of the ADP-ribose chain length and branching pattern.

Alvarez-Gonzalez R, Jacobson MK.

Methods Mol Biol. 2011;780:35-46. doi: 10.1007/978-1-61779-270-0_2.

PMID:
21870252
6.

Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG).

Steffen JD, Coyle DL, Damodaran K, Beroza P, Jacobson MK.

J Med Chem. 2011 Aug 11;54(15):5403-13. doi: 10.1021/jm200325s. Epub 2011 Jul 8.

7.

Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.

Bermudez Y, Benavente CA, Meyer RG, Coyle WR, Jacobson MK, Jacobson EL.

PLoS One. 2011;6(5):e20487. doi: 10.1371/journal.pone.0020487. Epub 2011 May 31.

8.

Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase.

Botta D, Jacobson MK.

Biochemistry. 2010 Sep 7;49(35):7674-82. doi: 10.1021/bi100973m.

9.

Photobiological implications of folate depletion and repletion in cultured human keratinocytes.

Williams JD, Jacobson MK.

J Photochem Photobiol B. 2010 Apr 2;99(1):49-61. doi: 10.1016/j.jphotobiol.2010.02.003. Epub 2010 Feb 6.

10.

A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

Whatcott CJ, Meyer-Ficca ML, Meyer RG, Jacobson MK.

Exp Cell Res. 2009 Dec 10;315(20):3477-85. doi: 10.1016/j.yexcr.2009.04.005. Epub 2009 Apr 21.

11.

NAD in skin: therapeutic approaches for niacin.

Benavente CA, Jacobson MK, Jacobson EL.

Curr Pharm Des. 2009;15(1):29-38. Review.

PMID:
19149600
12.

Validation of a simple and rapid HPLC method for determination of metronidazole in dermatological formulations.

Tashtoush BM, Jacobson EL, Jacobson MK.

Drug Dev Ind Pharm. 2008 Aug;34(8):840-4. doi: 10.1080/03639040801928598 .

PMID:
18618307
13.
14.

Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier.

Tashtoush BM, Kim H, Jacobson EL, Jacobson MK.

Drug Dev Ind Pharm. 2007 Nov;33(11):1176-82.

PMID:
18058313
15.

Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage.

Jacobson MK, Kim H, Coyle WR, Kim M, Coyle DL, Rizer RL, Jacobson EL.

Exp Dermatol. 2007 Nov;16(11):927-35.

PMID:
17927576
16.

A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin.

Jacobson EL, Kim H, Kim M, Williams JD, Coyle DL, Coyle WR, Grove G, Rizer RL, Stratton MS, Jacobson MK.

Exp Dermatol. 2007 Jun;16(6):490-9.

PMID:
17518989
17.

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

Meyer RG, Meyer-Ficca ML, Whatcott CJ, Jacobson EL, Jacobson MK.

Exp Cell Res. 2007 Aug 1;313(13):2920-36. Epub 2007 Apr 19.

18.

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.

Gao H, Coyle DL, Meyer-Ficca ML, Meyer RG, Jacobson EL, Wang ZQ, Jacobson MK.

Exp Cell Res. 2007 Mar 10;313(5):984-96. Epub 2007 Jan 10.

PMID:
17276427
19.

A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia.

Draelos ZD, Jacobson EL, Kim H, Kim M, Jacobson MK.

J Cosmet Dermatol. 2005 Dec;4(4):258-61.

PMID:
17168873
20.

Analysis and stability study of myristyl nicotinate in dermatological preparations by high-performance liquid chromatography.

Tashtoush BM, Qasem J, Williams JD, DeWald TP, Jacobson EL, Jacobson MK.

J Pharm Biomed Anal. 2007 Feb 19;43(3):893-9. Epub 2006 Oct 16.

PMID:
17049429
21.

A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations.

Tashtoush BM, Jacobson EL, Jacobson MK.

J Pharm Biomed Anal. 2007 Feb 19;43(3):859-64. Epub 2006 Oct 11.

PMID:
17045442
22.

Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection.

Wondrak GT, Jacobson MK, Jacobson EL.

Photochem Photobiol Sci. 2006 Feb;5(2):215-37. Epub 2005 Aug 19. Review.

PMID:
16465308
23.

Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent.

Catz P, Shinn W, Kapetanovic IM, Kim H, Kim M, Jacobson EL, Jacobson MK, Green CE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec 27;829(1-2):123-35. Epub 2005 Nov 7.

PMID:
16275131
24.

Antimelanoma activity of apoptogenic carbonyl scavengers.

Wondrak GT, Jacobson MK, Jacobson EL.

J Pharmacol Exp Ther. 2006 Feb;316(2):805-14. Epub 2005 Oct 6.

PMID:
16210394
25.

Poly(ADP-ribose) polymerases: managing genome stability.

Meyer-Ficca ML, Meyer RG, Jacobson EL, Jacobson MK.

Int J Biochem Cell Biol. 2005 May;37(5):920-6. Epub 2004 Dec 15. Review.

PMID:
15743666
26.

Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.

Cervantes-Laurean D, Roberts MJ, Jacobson EL, Jacobson MK.

Free Radic Biol Med. 2005 Mar 15;38(6):786-95.

PMID:
15721989
27.
28.

Poly(ADP-ribose) is required for spindle assembly and structure.

Chang P, Jacobson MK, Mitchison TJ.

Nature. 2004 Dec 2;432(7017):645-9.

PMID:
15577915
29.

Identification of quenchers of photoexcited States as novel agents for skin photoprotection.

Wondrak GT, Jacobson MK, Jacobson EL.

J Pharmacol Exp Ther. 2005 Feb;312(2):482-91. Epub 2004 Oct 8.

PMID:
15475591
30.

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

Cortes U, Tong WM, Coyle DL, Meyer-Ficca ML, Meyer RG, Petrilli V, Herceg Z, Jacobson EL, Jacobson MK, Wang ZQ.

Mol Cell Biol. 2004 Aug;24(16):7163-78.

31.

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments.

Meyer-Ficca ML, Meyer RG, Coyle DL, Jacobson EL, Jacobson MK.

Exp Cell Res. 2004 Jul 15;297(2):521-32.

PMID:
15212953
32.

3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells.

Wondrak GT, Roberts MJ, Jacobson MK, Jacobson EL.

J Biol Chem. 2004 Jul 16;279(29):30009-20. Epub 2004 May 7.

33.

ApoA-1 Milano and regression of atherosclerosis.

Kim H, Jacobson EL, Jacobson MK, Lacko AG.

JAMA. 2004 Mar 17;291(11):1319; author reply 1320. No abstract available.

PMID:
15026388
34.
35.

SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase.

Koh DW, Coyle DL, Mehta N, Ramsinghani S, Kim H, Slama JT, Jacobson MK.

J Med Chem. 2003 Sep 25;46(20):4322-32.

PMID:
13678410
36.

Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells.

Wondrak GT, Roberts MJ, Cervantes-Laurean D, Jacobson MK, Jacobson EL.

J Invest Dermatol. 2003 Sep;121(3):578-86.

37.

Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.

Koh DW, Patel CN, Ramsinghani S, Slama JT, Oliveira MA, Jacobson MK.

Biochemistry. 2003 May 6;42(17):4855-63.

PMID:
12718526
38.

Photosensitization of DNA damage by glycated proteins.

Wondrak GT, Jacobson EL, Jacobson MK.

Photochem Photobiol Sci. 2002 May;1(5):355-63.

PMID:
12653475
39.

Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors.

Cleary MP, Phillips FC, Getzin SC, Jacobson TL, Jacobson MK, Christensen TA, Juneja SC, Grande JP, Maihle NJ.

Breast Cancer Res Treat. 2003 Feb;77(3):205-15.

PMID:
12602920
40.

DNA damage by carbonyl stress in human skin cells.

Roberts MJ, Wondrak GT, Laurean DC, Jacobson MK, Jacobson EL.

Mutat Res. 2003 Jan 28;522(1-2):45-56.

PMID:
12517411
41.
42.
43.

Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress.

Wondrak GT, Cervantes-Laurean D, Roberts MJ, Qasem JG, Kim M, Jacobson EL, Jacobson MK.

Biochem Pharmacol. 2002 Feb 1;63(3):361-73.

PMID:
11853687
44.

Optimizing the energy status of skin cells during solar radiation.

Jacobson EL, Giacomoni PU, Roberts MJ, Wondrak GT, Jacobson MK.

J Photochem Photobiol B. 2001 Oct;63(1-3):141-7. Review.

PMID:
11684461
45.

NMR studies and semi-empirical energy calculations for cyclic ADP-ribose.

Rutherford TJ, Wilkie J, Vu CQ, Schnackerz KD, Jacobson MK, Gani D.

Nucleosides Nucleotides Nucleic Acids. 2001 Aug;20(8):1485-95.

PMID:
11554541
46.

Restoration of fertility in young obese (Lep(ob) Lep(ob)) male mice with low dose recombinant mouse leptin treatment.

Cleary MP, Bergstrom HM, Dodge TL, Getzin SC, Jacobson MK, Phillips FC.

Int J Obes Relat Metab Disord. 2001 Jan;25(1):95-7.

PMID:
11244463
47.

Histone carbonylation in vivo and in vitro.

Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK.

Biochem J. 2000 Nov 1;351 Pt 3:769-77.

48.

Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1.

Wondrak GT, Varadarajan S, Butterfield DA, Jacobson MK.

Free Radic Biol Med. 2000 Sep 15;29(6):557-67.

PMID:
11025199
49.

Discovering new ADP-ribose polymer cycles: protecting the genome and more.

Jacobson MK, Jacobson EL.

Trends Biochem Sci. 1999 Nov;24(11):415-7. Review. No abstract available.

PMID:
10542402
50.

Assignment of the poly(ADP-ribose) glycohydrolase gene (PARG) to human chromosome 10q11.23 and mouse chromosome 14B by in situ hybridization.

Amé JC, Apiou F, Jacobson EL, Jacobson MK.

Cytogenet Cell Genet. 1999;85(3-4):269-70. No abstract available.

PMID:
10449915

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