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Items: 1 to 50 of 105

1.

Vitamin B3 in Health and Disease: Toward the Second Century of Discovery.

Jacobson MK, Jacobson EL.

Methods Mol Biol. 2018;1813:3-8. doi: 10.1007/978-1-4939-8588-3_1. Review.

PMID:
30097857
2.

Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin.

Benavente CA, Schnell SA, Jacobson EL.

PLoS One. 2012;7(7):e42276. doi: 10.1371/journal.pone.0042276. Epub 2012 Jul 31.

3.

Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance.

Tome ME, Frye JB, Coyle DL, Jacobson EL, Samulitis BK, Dvorak K, Dorr RT, Briehl MM.

Exp Ther Med. 2012 May;3(5):845-852. Epub 2012 Feb 14.

4.

Vitamin B6: beyond coenzyme functions.

Wondrak GT, Jacobson EL.

Subcell Biochem. 2012;56:291-300. doi: 10.1007/978-94-007-2199-9_15. Review.

PMID:
22116705
5.

Folate in skin cancer prevention.

Williams JD, Jacobson EL, Kim H, Kim M, Jacobson MK.

Subcell Biochem. 2012;56:181-97. doi: 10.1007/978-94-007-2199-9_10. Review.

6.

Niacin: vitamin and antidyslipidemic drug.

Jacobson EL, Kim H, Kim M, Jacobson MK.

Subcell Biochem. 2012;56:37-47. doi: 10.1007/978-94-007-2199-9_3. Review.

PMID:
22116693
7.

Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.

Bermudez Y, Benavente CA, Meyer RG, Coyle WR, Jacobson MK, Jacobson EL.

PLoS One. 2011;6(5):e20487. doi: 10.1371/journal.pone.0020487. Epub 2011 May 31.

8.

NAD in skin: therapeutic approaches for niacin.

Benavente CA, Jacobson MK, Jacobson EL.

Curr Pharm Des. 2009;15(1):29-38. Review.

PMID:
19149600
9.

Validation of a simple and rapid HPLC method for determination of metronidazole in dermatological formulations.

Tashtoush BM, Jacobson EL, Jacobson MK.

Drug Dev Ind Pharm. 2008 Aug;34(8):840-4. doi: 10.1080/03639040801928598 .

PMID:
18618307
10.
11.

Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier.

Tashtoush BM, Kim H, Jacobson EL, Jacobson MK.

Drug Dev Ind Pharm. 2007 Nov;33(11):1176-82.

PMID:
18058313
12.

Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes.

Benavente CA, Jacobson EL.

Free Radic Biol Med. 2008 Feb 15;44(4):527-37. Epub 2007 Oct 17.

13.

Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage.

Jacobson MK, Kim H, Coyle WR, Kim M, Coyle DL, Rizer RL, Jacobson EL.

Exp Dermatol. 2007 Nov;16(11):927-35.

PMID:
17927576
14.

A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin.

Jacobson EL, Kim H, Kim M, Williams JD, Coyle DL, Coyle WR, Grove G, Rizer RL, Stratton MS, Jacobson MK.

Exp Dermatol. 2007 Jun;16(6):490-9.

PMID:
17518989
15.

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

Meyer RG, Meyer-Ficca ML, Whatcott CJ, Jacobson EL, Jacobson MK.

Exp Cell Res. 2007 Aug 1;313(13):2920-36. Epub 2007 Apr 19.

17.

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.

Gao H, Coyle DL, Meyer-Ficca ML, Meyer RG, Jacobson EL, Wang ZQ, Jacobson MK.

Exp Cell Res. 2007 Mar 10;313(5):984-96. Epub 2007 Jan 10.

PMID:
17276427
18.

A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia.

Draelos ZD, Jacobson EL, Kim H, Kim M, Jacobson MK.

J Cosmet Dermatol. 2005 Dec;4(4):258-61.

PMID:
17168873
19.

Analysis and stability study of myristyl nicotinate in dermatological preparations by high-performance liquid chromatography.

Tashtoush BM, Qasem J, Williams JD, DeWald TP, Jacobson EL, Jacobson MK.

J Pharm Biomed Anal. 2007 Feb 19;43(3):893-9. Epub 2006 Oct 16.

PMID:
17049429
20.

A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations.

Tashtoush BM, Jacobson EL, Jacobson MK.

J Pharm Biomed Anal. 2007 Feb 19;43(3):859-64. Epub 2006 Oct 11.

PMID:
17045442
21.

Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection.

Wondrak GT, Jacobson MK, Jacobson EL.

Photochem Photobiol Sci. 2006 Feb;5(2):215-37. Epub 2005 Aug 19. Review.

PMID:
16465308
22.

Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites.

Cervantes-Laurean D, Schramm DD, Jacobson EL, Halaweish I, Bruckner GG, Boissonneault GA.

J Nutr Biochem. 2006 Aug;17(8):531-40. Epub 2005 Oct 28.

PMID:
16443355
23.

Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent.

Catz P, Shinn W, Kapetanovic IM, Kim H, Kim M, Jacobson EL, Jacobson MK, Green CE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec 27;829(1-2):123-35. Epub 2005 Nov 7.

PMID:
16275131
24.

Antimelanoma activity of apoptogenic carbonyl scavengers.

Wondrak GT, Jacobson MK, Jacobson EL.

J Pharmacol Exp Ther. 2006 Feb;316(2):805-14. Epub 2005 Oct 6.

PMID:
16210394
25.

Poly(ADP-ribose) polymerases: managing genome stability.

Meyer-Ficca ML, Meyer RG, Jacobson EL, Jacobson MK.

Int J Biochem Cell Biol. 2005 May;37(5):920-6. Epub 2004 Dec 15. Review.

PMID:
15743666
26.

Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.

Cervantes-Laurean D, Roberts MJ, Jacobson EL, Jacobson MK.

Free Radic Biol Med. 2005 Mar 15;38(6):786-95.

PMID:
15721989
27.

Pilot study of low-dose interleukin-2, pegylated interferon-alpha 2b, and ribavirin for the treatment of hepatitis C virus infection in patients with HIV infection.

Glesby MJ, Bassett R, Alston-Smith B, Fichtenbaum C, Jacobson EL, Brass C, Owens S, Sulkowski M, Race EM, Sherman KE; AIDS Clinical Trials Group A5088 Protocol Team.

J Infect Dis. 2005 Mar 1;191(5):686-93. Epub 2005 Jan 26.

PMID:
15688281
28.

Identification of quenchers of photoexcited States as novel agents for skin photoprotection.

Wondrak GT, Jacobson MK, Jacobson EL.

J Pharmacol Exp Ther. 2005 Feb;312(2):482-91. Epub 2004 Oct 8.

PMID:
15475591
29.

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

Cortes U, Tong WM, Coyle DL, Meyer-Ficca ML, Meyer RG, Petrilli V, Herceg Z, Jacobson EL, Jacobson MK, Wang ZQ.

Mol Cell Biol. 2004 Aug;24(16):7163-78.

30.

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments.

Meyer-Ficca ML, Meyer RG, Coyle DL, Jacobson EL, Jacobson MK.

Exp Cell Res. 2004 Jul 15;297(2):521-32.

PMID:
15212953
31.

3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells.

Wondrak GT, Roberts MJ, Jacobson MK, Jacobson EL.

J Biol Chem. 2004 Jul 16;279(29):30009-20. Epub 2004 May 7.

32.

ApoA-1 Milano and regression of atherosclerosis.

Kim H, Jacobson EL, Jacobson MK, Lacko AG.

JAMA. 2004 Mar 17;291(11):1319; author reply 1320. No abstract available.

PMID:
15026388
33.
34.

Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells.

Wondrak GT, Roberts MJ, Cervantes-Laurean D, Jacobson MK, Jacobson EL.

J Invest Dermatol. 2003 Sep;121(3):578-86.

35.

Photosensitization of DNA damage by glycated proteins.

Wondrak GT, Jacobson EL, Jacobson MK.

Photochem Photobiol Sci. 2002 May;1(5):355-63.

PMID:
12653475
36.

DNA damage by carbonyl stress in human skin cells.

Roberts MJ, Wondrak GT, Laurean DC, Jacobson MK, Jacobson EL.

Mutat Res. 2003 Jan 28;522(1-2):45-56.

PMID:
12517411
37.
38.

Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients.

Bernstein H, Holubec H, Warneke JA, Garewal H, Earnest DL, Payne CM, Roe DJ, Cui H, Jacobson EL, Bernstein C.

Ann Surg Oncol. 2002 Jun;9(5):505-17.

PMID:
12052764
39.

Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress.

Wondrak GT, Cervantes-Laurean D, Roberts MJ, Qasem JG, Kim M, Jacobson EL, Jacobson MK.

Biochem Pharmacol. 2002 Feb 1;63(3):361-73.

PMID:
11853687
40.

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo.

Partida-Sánchez S, Cockayne DA, Monard S, Jacobson EL, Oppenheimer N, Garvy B, Kusser K, Goodrich S, Howard M, Harmsen A, Randall TD, Lund FE.

Nat Med. 2001 Nov;7(11):1209-16.

PMID:
11689885
41.

Optimizing the energy status of skin cells during solar radiation.

Jacobson EL, Giacomoni PU, Roberts MJ, Wondrak GT, Jacobson MK.

J Photochem Photobiol B. 2001 Oct;63(1-3):141-7. Review.

PMID:
11684461
42.

In vivo assessment of antiviral reactivity in chronic HIV infection.

Smith KA, Jacobson EL, Sohn T, Warren D, Emert R, Giordano M.

HIV Clin Trials. 2000 Nov-Dec;1(3):16-22.

PMID:
11590501
43.

Low-dose daily subcutaneous interleukin-2 in combination with highly active antiretroviral therapy in HIV+ patients: a randomized controlled trial.

Lalezari JP, Beal JA, Ruane PJ, Cohen CJ, Jacobson EL, Sundin D, Leong WP, Raffanti SP, Wheeler DA, Anderson RD, Keiser P, Schrader SR, Goodgame JC, Steinhart CR, Murphy RL, Wolin MJ, Smith KA.

HIV Clin Trials. 2000 Nov-Dec;1(3):1-15.

PMID:
11590500
44.

Modulation of VP-16 cytotoxicity by carboplatin and 41.8 degrees C hyperthermia.

Katschinski DM, Jacobson EL, Wiedemann GJ, Robins HI.

J Cancer Res Clin Oncol. 2001 Jul;127(7):425-32.

PMID:
11469679
45.

Restoration of immunity with interleukin-2 therapy.

Smith KA, Jacobson EL, Emert R, Giordano M, Kovacs E, Mumneh N, Pilaro F, Sohn T, Warren D.

AIDS Read. 1999 Nov;9(8):563-72. Review.

PMID:
11082734
46.

Histone carbonylation in vivo and in vitro.

Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK.

Biochem J. 2000 Nov 1;351 Pt 3:769-77.

47.

Discovering new ADP-ribose polymer cycles: protecting the genome and more.

Jacobson MK, Jacobson EL.

Trends Biochem Sci. 1999 Nov;24(11):415-7. Review. No abstract available.

PMID:
10542402
48.

Oral niacin prevents photocarcinogenesis and photoimmunosuppression in mice.

Gensler HL, Williams T, Huang AC, Jacobson EL.

Nutr Cancer. 1999;34(1):36-41.

PMID:
10453439
49.

Assignment of the poly(ADP-ribose) glycohydrolase gene (PARG) to human chromosome 10q11.23 and mouse chromosome 14B by in situ hybridization.

Amé JC, Apiou F, Jacobson EL, Jacobson MK.

Cytogenet Cell Genet. 1999;85(3-4):269-70. No abstract available.

PMID:
10449915
50.

Molecular heterogeneity and regulation of poly(ADP-ribose) glycohydrolase.

Amé JC, Jacobson EL, Jacobson MK.

Mol Cell Biochem. 1999 Mar;193(1-2):75-81.

PMID:
10331641

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