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Items: 1 to 50 of 58

1.

Mediation of plant-mycorrhizal interaction by a lectin receptor-like kinase.

Labbé J, Muchero W, Czarnecki O, Wang J, Wang X, Bryan AC, Zheng K, Yang Y, Xie M, Zhang J, Wang D, Meidl P, Wang H, Morrell-Falvey JL, Cope KR, Maia LGS, Ané JM, Mewalal R, Jawdy SS, Gunter LE, Schackwitz W, Martin J, Le Tacon F, Li T, Zhang Z, Ranjan P, Lindquist E, Yang X, Jacobson DA, Tschaplinski TJ, Barry K, Schmutz J, Chen JG, Tuskan GA.

Nat Plants. 2019 Jul;5(7):676-680. doi: 10.1038/s41477-019-0469-x. Epub 2019 Jul 8.

PMID:
31285560
2.

Accelerating Climate Resilient Plant Breeding by Applying Next-Generation Artificial Intelligence.

Harfouche AL, Jacobson DA, Kainer D, Romero JC, Harfouche AH, Scarascia Mugnozza G, Moshelion M, Tuskan GA, Keurentjes JJB, Altman A.

Trends Biotechnol. 2019 Jun 21. pii: S0167-7799(19)30114-3. doi: 10.1016/j.tibtech.2019.05.007. [Epub ahead of print] Review.

PMID:
31235329
3.

Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063.

Kharade SV, Sanchez-Andres JV, Fulton MG, Shelton EL, Blobaum AL, Engers DW, Hofmann CS, Dadi PK, Lantier L, Jacobson DA, Lindsley CW, Denton JS.

J Pharmacol Exp Ther. 2019 Sep;370(3):350-359. doi: 10.1124/jpet.119.257204. Epub 2019 Jun 14.

PMID:
31201216
4.

Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice.

Yaw AM, Prosser RA, Jones PC, Garcia BJ, Jacobson DA, Glass JD.

Behav Brain Res. 2019 Jul 23;367:68-81. doi: 10.1016/j.bbr.2019.02.043. Epub 2019 Mar 22.

PMID:
30910707
5.

Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.

Dickerson MT, Dadi PK, Altman MK, Verlage KR, Thorson AS, Jordan KL, Vierra NC, Amarnath G, Jacobson DA.

Am J Physiol Endocrinol Metab. 2019 Apr 1;316(4):E646-E659. doi: 10.1152/ajpendo.00342.2018. Epub 2019 Jan 29.

PMID:
30694690
6.

Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.

Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G.

Dev Cell. 2019 Jan 7;48(1):49-63.e7. doi: 10.1016/j.devcel.2018.11.048.

PMID:
30620902
7.

Exploration of the Biosynthetic Potential of the Populus Microbiome.

Blair PM, Land ML, Piatek MJ, Jacobson DA, Lu TS, Doktycz MJ, Pelletier DA.

mSystems. 2018 Oct 2;3(5). pii: e00045-18. doi: 10.1128/mSystems.00045-18. eCollection 2018 Sep-Oct.

8.

Defining the genetic components of callus formation: A GWAS approach.

Tuskan GA, Mewalal R, Gunter LE, Palla KJ, Carter K, Jacobson DA, Jones PC, Garcia BJ, Weighill DA, Hyatt PD, Yang Y, Zhang J, Reis N, Chen JG, Muchero W.

PLoS One. 2018 Aug 17;13(8):e0202519. doi: 10.1371/journal.pone.0202519. eCollection 2018.

9.

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.

Navarro G, Allard C, Morford JJ, Xu W, Liu S, Molinas AJ, Butcher SM, Fine NH, Blandino-Rosano M, Sure VN, Yu S, Zhang R, Münzberg H, Jacobson DA, Katakam PV, Hodson DJ, Bernal-Mizrachi E, Zsombok A, Mauvais-Jarvis F.

JCI Insight. 2018 Jun 21;3(12). pii: 98607. doi: 10.1172/jci.insight.98607. eCollection 2018 Jun 21.

10.

Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

Hart NJ, Aramandla R, Poffenberger G, Fayolle C, Thames AH, Bautista A, Spigelman AF, Babon JAB, DeNicola ME, Dadi PK, Bush WS, Balamurugan AN, Brissova M, Dai C, Prasad N, Bottino R, Jacobson DA, Drumm ML, Kent SC, MacDonald PE, Powers AC.

JCI Insight. 2018 Apr 19;3(8). pii: 98240. doi: 10.1172/jci.insight.98240. eCollection 2018 Apr 19.

11.

Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.

Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ Jr, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G.

Dev Cell. 2018 May 7;45(3):347-361.e5. doi: 10.1016/j.devcel.2018.03.013. Epub 2018 Apr 12.

12.

Genus-Wide Assessment of Lignocellulose Utilization in the Extremely Thermophilic Genus Caldicellulosiruptor by Genomic, Pangenomic, and Metagenomic Analyses.

Lee LL, Blumer-Schuette SE, Izquierdo JA, Zurawski JV, Loder AJ, Conway JM, Elkins JG, Podar M, Clum A, Jones PC, Piatek MJ, Weighill DA, Jacobson DA, Adams MWW, Kelly RM.

Appl Environ Microbiol. 2018 Apr 16;84(9). pii: e02694-17. doi: 10.1128/AEM.02694-17. Print 2018 May 1.

13.

Quantitative proteome profile of water deficit stress responses in eastern cottonwood (Populus deltoides) leaves.

Abraham PE, Garcia BJ, Gunter LE, Jawdy SS, Engle N, Yang X, Jacobson DA, Hettich RL, Tuskan GA, Tschaplinski TJ.

PLoS One. 2018 Feb 15;13(2):e0190019. doi: 10.1371/journal.pone.0190019. eCollection 2018.

14.

TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion.

Vierra NC, Dickerson MT, Jordan KL, Dadi PK, Katdare KA, Altman MK, Milian SC, Jacobson DA.

Mol Metab. 2018 Mar;9:84-97. doi: 10.1016/j.molmet.2018.01.016. Epub 2018 Jan 31.

15.

Cytokine-mediated changes in K+ channel activity promotes an adaptive Ca2+ response that sustains β-cell insulin secretion during inflammation.

Dickerson MT, Bogart AM, Altman MK, Milian SC, Jordan KL, Dadi PK, Jacobson DA.

Sci Rep. 2018 Jan 18;8(1):1158. doi: 10.1038/s41598-018-19600-x.

16.

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.

Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ.

Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4.

17.

The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism.

Yang X, Hu R, Yin H, Jenkins J, Shu S, Tang H, Liu D, Weighill DA, Cheol Yim W, Ha J, Heyduk K, Goodstein DM, Guo HB, Moseley RC, Fitzek E, Jawdy S, Zhang Z, Xie M, Hartwell J, Grimwood J, Abraham PE, Mewalal R, Beltrán JD, Boxall SF, Dever LV, Palla KJ, Albion R, Garcia T, Mayer JA, Don Lim S, Man Wai C, Peluso P, Van Buren R, De Paoli HC, Borland AM, Guo H, Chen JG, Muchero W, Yin Y, Jacobson DA, Tschaplinski TJ, Hettich RL, Ming R, Winter K, Leebens-Mack JH, Smith JAC, Cushman JC, Schmutz J, Tuskan GA.

Nat Commun. 2017 Dec 1;8(1):1899. doi: 10.1038/s41467-017-01491-7.

18.

Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on β-Cell Function.

Vierra NC, Dickerson MT, Philipson LH, Jacobson DA.

Methods Mol Biol. 2018;1684:73-84. doi: 10.1007/978-1-4939-7362-0_7.

19.

TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis.

Vierra NC, Dadi PK, Milian SC, Dickerson MT, Jordan KL, Gilon P, Jacobson DA.

Sci Signal. 2017 Sep 19;10(497). pii: eaan2883. doi: 10.1126/scisignal.aan2883.

20.

A novel mechanism for Ca2+/calmodulin-dependent protein kinase II targeting to L-type Ca2+ channels that initiates long-range signaling to the nucleus.

Wang X, Marks CR, Perfitt TL, Nakagawa T, Lee A, Jacobson DA, Colbran RJ.

J Biol Chem. 2017 Oct 20;292(42):17324-17336. doi: 10.1074/jbc.M117.788331. Epub 2017 Sep 15.

21.

Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes.

Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA.

Diabetes. 2017 Aug;66(8):2175-2187. doi: 10.2337/db16-1355. Epub 2017 May 26.

22.

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.

Dickerson MT, Vierra NC, Milian SC, Dadi PK, Jacobson DA.

PLoS One. 2017 Apr 12;12(4):e0175069. doi: 10.1371/journal.pone.0175069. eCollection 2017.

23.

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.

Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, Leapman RD, Matschinsky FM, Doliba NM, Urs NM, Caron MG, Jacobson DA, Caicedo A, Wess J.

Nat Commun. 2017 Feb 1;8:14295. doi: 10.1038/ncomms14295.

24.

Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.

Dadi PK, Vierra NC, Days E, Dickerson MT, Vinson PN, Weaver CD, Jacobson DA.

ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. doi: 10.1021/acschemneuro.6b00301. Epub 2016 Nov 23.

25.

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.

Boortz KA, Syring KE, Dai C, Pound LD, Oeser JK, Jacobson DA, Wang JC, McGuinness OP, Powers AC, O'Brien RM.

Endocrinology. 2016 Aug;157(8):3002-8. doi: 10.1210/en.2016-1245. Epub 2016 Jun 14.

26.

Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.

Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F.

Cell Metab. 2016 May 10;23(5):837-51. doi: 10.1016/j.cmet.2016.03.015. Epub 2016 Apr 28.

27.

Characterization of DWARF14 Genes in Populus.

Zheng K, Wang X, Weighill DA, Guo HB, Xie M, Yang Y, Yang J, Wang S, Jacobson DA, Guo H, Muchero W, Tuskan GA, Chen JG.

Sci Rep. 2016 Feb 15;6:21593. doi: 10.1038/srep21593.

28.

Grapevine Plasticity in Response to an Altered Microclimate: Sauvignon Blanc Modulates Specific Metabolites in Response to Increased Berry Exposure.

Young PR, Eyeghe-Bickong HA, du Plessis K, Alexandersson E, Jacobson DA, Coetzee Z, Deloire A, Vivier MA.

Plant Physiol. 2016 Mar;170(3):1235-54. doi: 10.1104/pp.15.01775. Epub 2015 Dec 1.

29.

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion.

Golson ML, Dunn JC, Maulis MF, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, Gannon M.

Diabetes. 2015 Nov;64(11):3829-38. doi: 10.2337/db15-0465. Epub 2015 Aug 6.

30.

Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis.

Vierra NC, Dadi PK, Jeong I, Dickerson M, Powell DR, Jacobson DA.

Diabetes. 2015 Nov;64(11):3818-28. doi: 10.2337/db15-0280. Epub 2015 Aug 3.

31.

Levels of evidence: a comparison between top medical journals and general pediatric journals.

Jacobson DA, Bhanot K, Yarascavitch B, Chuback J, Rosenbloom E, Bhandari M.

BMC Pediatr. 2015 Feb 12;15:3. doi: 10.1186/s12887-015-0324-9.

32.

TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion.

Dadi PK, Luo B, Vierra NC, Jacobson DA.

Mol Endocrinol. 2015 May;29(5):777-87. doi: 10.1210/me.2014-1321. Epub 2015 Apr 7.

33.

3-way networks: application of hypergraphs for modelling increased complexity in comparative genomics.

Weighill DA, Jacobson DA.

PLoS Comput Biol. 2015 Mar 27;11(3):e1004079. doi: 10.1371/journal.pcbi.1004079. eCollection 2015 Mar.

34.

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload.

Egnatchik RA, Leamy AK, Jacobson DA, Shiota M, Young JD.

Mol Metab. 2014 May 22;3(5):544-53. doi: 10.1016/j.molmet.2014.05.004. eCollection 2014 Aug.

35.

Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance.

Dadi PK, Vierra NC, Jacobson DA.

Endocrinology. 2014 Oct;155(10):3757-68. doi: 10.1210/en.2013-2051. Epub 2014 Jun 16.

36.

Direct activation of β-cell KATP channels with a novel xanthine derivative.

Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS.

Mol Pharmacol. 2014 Jun;85(6):858-65. doi: 10.1124/mol.114.091884. Epub 2014 Mar 19.

37.

Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance.

Dadi PK, Vierra NC, Ustione A, Piston DW, Colbran RJ, Jacobson DA.

J Biol Chem. 2014 May 2;289(18):12435-45. doi: 10.1074/jbc.M114.562587. Epub 2014 Mar 13.

38.

Network processes involved in the mediation of short-term habituation in Aplysia: contribution of intrinsic regulation of excitability and synaptic augmentation.

Fischer TM, Jacobson DA, Demorest-Hayes K.

Front Integr Neurosci. 2014 Feb 13;8:15. doi: 10.3389/fnint.2014.00015. eCollection 2014.

39.

Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis.

Fridlyand LE, Jacobson DA, Philipson LH.

Islets. 2013 Jan-Feb;5(1):1-15. doi: 10.4161/isl.24166. Review.

40.

Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.

Baerenwald DA, Bonnefond A, Bouatia-Naji N, Flemming BP, Umunakwe OC, Oeser JK, Pound LD, Conley NL, Cauchi S, Lobbens S, Eury E, Balkau B, Lantieri O; MAGIC Investigators, Dadi PK, Jacobson DA, Froguel P, O'Brien RM.

Diabetologia. 2013 Jun;56(6):1306-16. doi: 10.1007/s00125-013-2875-3. Epub 2013 Mar 19.

41.

β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion.

Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B.

Diabetes. 2013 May;62(5):1527-36. doi: 10.2337/db12-1013. Epub 2013 Jan 24.

42.

G6PC2: a negative regulator of basal glucose-stimulated insulin secretion.

Pound LD, Oeser JK, O'Brien TP, Wang Y, Faulman CJ, Dadi PK, Jacobson DA, Hutton JC, McGuinness OP, Shiota M, O'Brien RM.

Diabetes. 2013 May;62(5):1547-56. doi: 10.2337/db12-1067. Epub 2012 Dec 28.

43.

The physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic background.

Pound LD, Sarkar SA, Ustione A, Dadi PK, Shadoan MK, Lee CE, Walters JA, Shiota M, McGuinness OP, Jacobson DA, Piston DW, Hutton JC, Powell DR, O'Brien RM.

PLoS One. 2012;7(7):e40972. doi: 10.1371/journal.pone.0040972. Epub 2012 Jul 19.

44.

Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.

Denton JS, Jacobson DA.

Trends Endocrinol Metab. 2012 Jan;23(1):41-8. doi: 10.1016/j.tem.2011.09.004. Epub 2011 Nov 29. Review.

45.

Regulation of low-threshold afferent activity may contribute to short-term habituation in Aplysia californica.

Fischer TM, Jacobson DA, Counsell AN, Pelot MA, Demorest K.

Neurobiol Learn Mem. 2011 Mar;95(3):248-59. doi: 10.1016/j.nlm.2010.11.016. Epub 2010 Dec 7.

PMID:
21144906
46.

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.

Jacobson DA, Mendez F, Thompson M, Torres J, Cochet O, Philipson LH.

J Physiol. 2010 Sep 15;588(Pt 18):3525-37. doi: 10.1113/jphysiol.2010.190207. Epub 2010 Jul 19.

47.

The granular chloride channel ClC-3 is permissive for insulin secretion.

Deriy LV, Gomez EA, Jacobson DA, Wang X, Hopson JA, Liu XY, Zhang G, Bindokas VP, Philipson LH, Nelson DJ.

Cell Metab. 2009 Oct;10(4):316-23. doi: 10.1016/j.cmet.2009.08.012.

48.

A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cells.

Fridlyand LE, Jacobson DA, Kuznetsov A, Philipson LH.

Biophys J. 2009 Apr 22;96(8):3126-39. doi: 10.1016/j.bpj.2009.01.029.

49.

The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing.

Jacobson DA, Wicksteed BL, Philipson LH.

Diabetes. 2009 Feb;58(2):304-6. doi: 10.2337/db08-1618. No abstract available.

50.

Action potentials and insulin secretion: new insights into the role of Kv channels.

Jacobson DA, Philipson LH.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:89-98.

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