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Items: 1 to 50 of 405

1.

Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action.

Yan Y, Liu Q, Zang X, Yuan S, Bat-Erdene U, Nguyen C, Gan J, Zhou J, Jacobsen SE, Tang Y.

Nature. 2018 Jul;559(7714):415-418. doi: 10.1038/s41586-018-0319-4. Epub 2018 Jul 11.

PMID:
29995859
2.

The effect of lactic acid bacteria inoculation, molasses or wilting on the fermentation quality and nutritive value of amaranth (Amaranthus hypochondriaus) silage.

Abbasi M, Rouzbehan Y, Rezaei J, Jacobsen SE.

J Anim Sci. 2018 Jun 25. doi: 10.1093/jas/sky257. [Epub ahead of print]

PMID:
29939261
3.

TFAP2C regulates transcription in human naive pluripotency by opening enhancers.

Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen SE, Clark AT.

Nat Cell Biol. 2018 May;20(5):553-564. doi: 10.1038/s41556-018-0089-0. Epub 2018 Apr 25.

PMID:
29695788
4.

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells.

Neo WH, Booth CAG, Azzoni E, Chi L, Delgado-Olguín P, de Bruijn MFTR, Jacobsen SEW, Mead AJ.

Blood. 2018 May 17;131(20):2223-2234. doi: 10.1182/blood-2017-10-811455. Epub 2018 Mar 19.

PMID:
29555646
5.

In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche.

Breitbach M, Kimura K, Luis TC, Fuegemann CJ, Woll PS, Hesse M, Facchini R, Rieck S, Jobin K, Reinhardt J, Ohneda O, Wenzel D, Geisen C, Kurts C, Kastenmüller W, Hölzel M, Jacobsen SEW, Fleischmann BK.

Cell Stem Cell. 2018 Feb 1;22(2):262-276.e7. doi: 10.1016/j.stem.2018.01.008.

PMID:
29451855
6.

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain.

Gallego-Bartolomé J, Gardiner J, Liu W, Papikian A, Ghoshal B, Kuo HY, Zhao JM, Segal DJ, Jacobsen SE.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2125-E2134. doi: 10.1073/pnas.1716945115. Epub 2018 Feb 14.

7.

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.

Booth CAG, Barkas N, Neo WH, Boukarabila H, Soilleux EJ, Giotopoulos G, Farnoud N, Giustacchini A, Ashley N, Carrelha J, Jamieson L, Atkinson D, Bouriez-Jones T, Prinjha RK, Milne TA, Teachey DT, Papaemmanuil E, Huntly BJP, Jacobsen SEW, Mead AJ.

Cancer Cell. 2018 Feb 12;33(2):274-291.e8. doi: 10.1016/j.ccell.2018.01.006.

PMID:
29438697
8.

RNA-directed DNA methylation involves co-transcriptional small-RNA-guided slicing of polymerase V transcripts in Arabidopsis.

Liu W, Duttke SH, Hetzel J, Groth M, Feng S, Gallego-Bartolome J, Zhong Z, Kuo HY, Wang Z, Zhai J, Chory J, Jacobsen SE.

Nat Plants. 2018 Mar;4(3):181-188. doi: 10.1038/s41477-017-0100-y. Epub 2018 Jan 29.

PMID:
29379150
9.

Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis.

Zhang Y, Harris CJ, Liu Q, Liu W, Ausin I, Long Y, Xiao L, Feng L, Chen X, Xie Y, Chen X, Zhan L, Feng S, Li JJ, Wang H, Zhai J, Jacobsen SE.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1069-E1074. doi: 10.1073/pnas.1716300115. Epub 2018 Jan 16.

10.

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S, Woll PS, Buza-Vidas N, Chin DWL, Boukarabila H, Luís TC, Stenson L, Bouriez-Jones T, Ferry H, Mead AJ, Atkinson D, Jin S, Clark SA, Wu B, Repapi E, Gray N, Taylor S, Mutvei AP, Tsoi YL, Nerlov C, Lendahl U, Jacobsen SEW.

Blood. 2018 Apr 12;131(15):1712-1719. doi: 10.1182/blood-2017-06-788505. Epub 2018 Jan 16.

PMID:
29339402
11.

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.

Carrelha J, Meng Y, Kettyle LM, Luis TC, Norfo R, Alcolea V, Boukarabila H, Grasso F, Gambardella A, Grover A, Högstrand K, Lord AM, Sanjuan-Pla A, Woll PS, Nerlov C, Jacobsen SEW.

Nature. 2018 Feb 1;554(7690):106-111. doi: 10.1038/nature25455. Epub 2018 Jan 3.

PMID:
29298288
12.

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.

Böiers C, Richardson SE, Laycock E, Zriwil A, Turati VA, Brown J, Wray JP, Wang D, James C, Herrero J, Sitnicka E, Karlsson S, Smith AJH, Jacobsen SEW, Enver T.

Dev Cell. 2018 Feb 5;44(3):362-377.e7. doi: 10.1016/j.devcel.2017.12.005. Epub 2017 Dec 28.

13.

Germline competency of human embryonic stem cells depends on eomesodermin.

Chen D, Liu W, Lukianchikov A, Hancock GV, Zimmerman J, Lowe MG, Kim R, Galic Z, Irie N, Surani MA, Jacobsen SE, Clark AT.

Biol Reprod. 2017 Jan 1;97(6):850-861. doi: 10.1093/biolre/iox138.

PMID:
29091993
14.

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation.

Riffelmacher T, Clarke A, Richter FC, Stranks A, Pandey S, Danielli S, Hublitz P, Yu Z, Johnson E, Schwerd T, McCullagh J, Uhlig H, Jacobsen SEW, Simon AK.

Immunity. 2017 Sep 19;47(3):466-480.e5. doi: 10.1016/j.immuni.2017.08.005. Epub 2017 Sep 12.

15.

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.

Loughran SJ, Comoglio F, Hamey FK, Giustacchini A, Errami Y, Earp E, Göttgens B, Jacobsen SEW, Mead AJ, Hendrich B, Green AR.

J Exp Med. 2017 Oct 2;214(10):3085-3104. doi: 10.1084/jem.20161827. Epub 2017 Sep 12.

16.

Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2017 Aug 31;6. pii: e30948. doi: 10.7554/eLife.30948. No abstract available.

17.

Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.

Unnikrishnan A, Papaemmanuil E, Beck D, Deshpande NP, Verma A, Kumari A, Woll PS, Richards LA, Knezevic K, Chandrakanthan V, Thoms JAI, Tursky ML, Huang Y, Ali Z, Olivier J, Galbraith S, Kulasekararaj AG, Tobiasson M, Karimi M, Pellagatti A, Wilson SR, Lindeman R, Young B, Ramakrishna R, Arthur C, Stark R, Crispin P, Curnow J, Warburton P, Roncolato F, Boultwood J, Lynch K, Jacobsen SEW, Mufti GJ, Hellstrom-Lindberg E, Wilkins MR, MacKenzie KL, Wong JWH, Campbell PJ, Pimanda JE.

Cell Rep. 2017 Jul 18;20(3):572-585. doi: 10.1016/j.celrep.2017.06.067.

18.

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Mead AJ, Neo WH, Barkas N, Matsuoka S, Giustacchini A, Facchini R, Thongjuea S, Jamieson L, Booth CAG, Fordham N, Di Genua C, Atkinson D, Chowdhury O, Repapi E, Gray N, Kharazi S, Clark SA, Bouriez T, Woll P, Suda T, Nerlov C, Jacobsen SEW.

J Exp Med. 2017 Jul 3;214(7):2005-2021. doi: 10.1084/jem.20161418. Epub 2017 Jun 21.

19.

SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells.

Mortera-Blanco T, Dimitriou M, Woll PS, Karimi M, Elvarsdottir E, Conte S, Tobiasson M, Jansson M, Douagi I, Moarii M, Saft L, Papaemmanuil E, Jacobsen SEW, Hellström-Lindberg E.

Blood. 2017 Aug 17;130(7):881-890. doi: 10.1182/blood-2017-03-776070. Epub 2017 Jun 20.

20.

MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality.

Weiser NE, Yang DX, Feng S, Kalinava N, Brown KC, Khanikar J, Freeberg MA, Snyder MJ, Csankovszki G, Chan RC, Gu SG, Montgomery TA, Jacobsen SE, Kim JK.

Dev Cell. 2017 May 22;41(4):408-423.e7. doi: 10.1016/j.devcel.2017.04.023.

21.

The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana.

Wollmann H, Stroud H, Yelagandula R, Tarutani Y, Jiang D, Jing L, Jamge B, Takeuchi H, Holec S, Nie X, Kakutani T, Jacobsen SE, Berger F.

Genome Biol. 2017 May 18;18(1):94. doi: 10.1186/s13059-017-1221-3.

22.

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A, Thongjuea S, Barkas N, Woll PS, Povinelli BJ, Booth CAG, Sopp P, Norfo R, Rodriguez-Meira A, Ashley N, Jamieson L, Vyas P, Anderson K, Segerstolpe Å, Qian H, Olsson-Strömberg U, Mustjoki S, Sandberg R, Jacobsen SEW, Mead AJ.

Nat Med. 2017 Jun;23(6):692-702. doi: 10.1038/nm.4336. Epub 2017 May 15.

PMID:
28504724
23.

Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer.

Jacobsen SE, Gether U, Bräuner-Osborne H.

Sci Rep. 2017 Apr 18;7:46355. doi: 10.1038/srep46355.

24.

The GPRC6A receptor displays constitutive internalization and sorting to the slow recycling pathway.

Jacobsen SE, Ammendrup-Johnsen I, Jansen AM, Gether U, Madsen KL, Bräuner-Osborne H.

J Biol Chem. 2017 Apr 28;292(17):6910-6926. doi: 10.1074/jbc.M116.762385. Epub 2017 Mar 9.

25.

Corrigendum: SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation.

Johnson LM, Du J, Hale CJ, Bischof S, Feng S, Chodavarapu RK, Zhong X, Marson G, Pellegrini M, Segal DJ, Patel DJ, Jacobsen SE.

Nature. 2017 Mar 2;543(7643):136. doi: 10.1038/nature21398. Epub 2017 Feb 8. No abstract available.

PMID:
28178234
26.

Large-scale heterochromatin remodeling linked to overreplication-associated DNA damage.

Feng W, Hale CJ, Over RS, Cokus SJ, Jacobsen SE, Michaels SD.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):406-411. doi: 10.1073/pnas.1619774114. Epub 2016 Dec 27.

27.

Evidence for ARGONAUTE4-DNA interactions in RNA-directed DNA methylation in plants.

Lahmy S, Pontier D, Bies-Etheve N, Laudié M, Feng S, Jobet E, Hale CJ, Cooke R, Hakimi MA, Angelov D, Jacobsen SE, Lagrange T.

Genes Dev. 2016 Dec 1;30(23):2565-2570. doi: 10.1101/gad.289553.116. Epub 2016 Dec 16.

28.

DNA methylome of the 20-gigabase Norway spruce genome.

Ausin I, Feng S, Yu C, Liu W, Kuo HY, Jacobsen EL, Zhai J, Gallego-Bartolome J, Wang L, Egertsdotter U, Street NR, Jacobsen SE, Wang H.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8106-E8113. Epub 2016 Nov 28.

29.

Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations.

Scharenberg C, Giai V, Pellagatti A, Saft L, Dimitriou M, Jansson M, Jädersten M, Grandien A, Douagi I, Neuberg DS, LeBlanc K, Boultwood J, Karimi M, Jacobsen SE, Woll PS, Hellström-Lindberg E.

Haematologica. 2017 Mar;102(3):498-508. doi: 10.3324/haematol.2016.152025. Epub 2016 Nov 24.

30.

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T, Vaidya H, Mead AJ, Atkinson D, Böiers C, Carrelha J, Macaulay IC, Patient R, Geissmann F, Nerlov C, Sandberg R, de Bruijn MFTR, Blackburn CC, Godin I, Jacobsen SEW.

Nat Immunol. 2016 Dec;17(12):1424-1435. doi: 10.1038/ni.3576. Epub 2016 Oct 3.

31.

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality.

Dimitriou M, Woll PS, Mortera-Blanco T, Karimi M, Wedge DC, Doolittle H, Douagi I, Papaemmanuil E, Jacobsen SE, Hellström-Lindberg E.

Oncotarget. 2016 Nov 8;7(45):72685-72698. doi: 10.18632/oncotarget.12234.

32.

Elevated Genetic Diversity in an F2:6 Population of Quinoa (Chenopodium quinoa) Developed through an Inter-ecotype Cross.

Benlhabib O, Boujartani N, Maughan PJ, Jacobsen SE, Jellen EN.

Front Plant Sci. 2016 Aug 17;7:1222. doi: 10.3389/fpls.2016.01222. eCollection 2016.

33.

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin.

Li S, Yen L, Pastor WA, Johnston JB, Du J, Shew CJ, Liu W, Ho J, Stender B, Clark AT, Burlingame AL, Daxinger L, Patel DJ, Jacobsen SE.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5108-16. doi: 10.1073/pnas.1609709113. Epub 2016 Aug 15.

34.

On the origin and evolutionary consequences of gene body DNA methylation.

Bewick AJ, Ji L, Niederhuth CE, Willing EM, Hofmeister BT, Shi X, Wang L, Lu Z, Rohr NA, Hartwig B, Kiefer C, Deal RB, Schmutz J, Grimwood J, Stroud H, Jacobsen SE, Schneeberger K, Zhang X, Schmitz RJ.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9111-6. doi: 10.1073/pnas.1604666113. Epub 2016 Jul 25.

35.

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.

Barrett NA, Malouf C, Kapeni C, Bacon WA, Giotopoulos G, Jacobsen SEW, Huntly BJ, Ottersbach K.

Cell Rep. 2016 Jul 26;16(4):1039-1054. doi: 10.1016/j.celrep.2016.06.046. Epub 2016 Jul 7.

36.

MTHFD1 controls DNA methylation in Arabidopsis.

Groth M, Moissiard G, Wirtz M, Wang H, Garcia-Salinas C, Ramos-Parra PA, Bischof S, Feng S, Cokus SJ, John A, Smith DC, Zhai J, Hale CJ, Long JA, Hell R, Díaz de la Garza RI, Jacobsen SE.

Nat Commun. 2016 Jun 13;7:11640. doi: 10.1038/ncomms11640.

37.

Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana.

Hale CJ, Potok ME, Lopez J, Do T, Liu A, Gallego-Bartolome J, Michaels SD, Jacobsen SE.

PLoS Genet. 2016 Jun 2;12(6):e1006092. doi: 10.1371/journal.pgen.1006092. eCollection 2016 Jun.

38.

The Global Expansion of Quinoa: Trends and Limits.

Bazile D, Jacobsen SE, Verniau A.

Front Plant Sci. 2016 May 9;7:622. doi: 10.3389/fpls.2016.00622. eCollection 2016. Review.

39.

Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice.

Zriwil A, Böiers C, Wittmann L, Green JC, Woll PS, Jacobsen SE, Sitnicka E.

Blood. 2016 Jul 14;128(2):217-26. doi: 10.1182/blood-2016-01-693887. Epub 2016 May 17.

40.

Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.

Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen SE.

PLoS Genet. 2016 May 12;12(5):e1005998. doi: 10.1371/journal.pgen.1005998. eCollection 2016 May.

41.

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R, Buza-Vidas N, Woll P, Thongjuea S, Gambardella A, Giustacchini A, Mancini E, Zriwil A, Lutteropp M, Grover A, Mead A, Sitnicka E, Jacobsen SEW, Nerlov C.

Nat Immunol. 2016 Jun;17(6):666-676. doi: 10.1038/ni.3412. Epub 2016 Apr 4.

42.

Primitive Embryonic Macrophages are Required for Coronary Development and Maturation.

Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ.

Circ Res. 2016 May 13;118(10):1498-511. doi: 10.1161/CIRCRESAHA.115.308270. Epub 2016 Mar 23.

43.

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Grover A, Sanjuan-Pla A, Thongjuea S, Carrelha J, Giustacchini A, Gambardella A, Macaulay I, Mancini E, Luis TC, Mead A, Jacobsen SE, Nerlov C.

Nat Commun. 2016 Mar 24;7:11075. doi: 10.1038/ncomms11075.

44.

Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette.

Li S, Yang Z, Du X, Liu R, Wilkinson AW, Gozani O, Jacobsen SE, Patel DJ, Du J.

Structure. 2016 Mar 1;24(3):486-94. doi: 10.1016/j.str.2016.01.004. Epub 2016 Feb 11.

45.

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory.

Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT.

Cell Stem Cell. 2016 Mar 3;18(3):323-329. doi: 10.1016/j.stem.2016.01.019. Epub 2016 Feb 4.

46.

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

Buono M, Facchini R, Matsuoka S, Thongjuea S, Waithe D, Luis TC, Giustacchini A, Besmer P, Mead AJ, Jacobsen SE, Nerlov C.

Nat Cell Biol. 2016 Feb;18(2):157-67. doi: 10.1038/ncb3299. Epub 2016 Jan 18.

47.

C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.

Zhang S, Zhou B, Kang Y, Cui X, Liu A, Deleris A, Greenberg MV, Cui X, Qiu Q, Lu F, Wohlschlegel JA, Jacobsen SE, Cao X.

Cell Discov. 2015;1. pii: 15003. Epub 2015 Apr 28.

48.

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

Watson AS, Riffelmacher T, Stranks A, Williams O, De Boer J, Cain K, MacFarlane M, McGouran J, Kessler B, Khandwala S, Chowdhury O, Puleston D, Phadwal K, Mortensen M, Ferguson D, Soilleux E, Woll P, Jacobsen SE, Simon AK.

Cell Death Discov. 2015 Aug 17;1. pii: 15008.

49.

CG gene body DNA methylation changes and evolution of duplicated genes in cassava.

Wang H, Beyene G, Zhai J, Feng S, Fahlgren N, Taylor NJ, Bart R, Carrington JC, Jacobsen SE, Ausin I.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13729-34. doi: 10.1073/pnas.1519067112. Epub 2015 Oct 19.

50.

A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis.

Zhai J, Bischof S, Wang H, Feng S, Lee TF, Teng C, Chen X, Park SY, Liu L, Gallego-Bartolome J, Liu W, Henderson IR, Meyers BC, Ausin I, Jacobsen SE.

Cell. 2015 Oct 8;163(2):445-55. doi: 10.1016/j.cell.2015.09.032.

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