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Items: 1 to 50 of 82

1.

Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice.

Hadrup N, Rahmani F, Jacobsen NR, Saber AT, Jackson P, Bengtson S, Williams A, Wallin H, Halappanavar S, Vogel U.

Nanotoxicology. 2019 Nov;13(9):1275-1292. doi: 10.1080/17435390.2019.1654004. Epub 2019 Aug 23.

PMID:
31441356
2.

Pulmonary toxicity of two different multi-walled carbon nanotubes in rat: Comparison between intratracheal instillation and inhalation exposure.

Gaté L, Knudsen KB, Seidel C, Berthing T, Chézeau L, Jacobsen NR, Valentino S, Wallin H, Bau S, Wolff H, Sébillaud S, Lorcin M, Grossmann S, Viton S, Nunge H, Darne C, Vogel U, Cosnier F.

Toxicol Appl Pharmacol. 2019 Jul 15;375:17-31. doi: 10.1016/j.taap.2019.05.001. Epub 2019 May 7. Spanish.

PMID:
31075343
3.

Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation.

Mech A, Rasmussen K, Jantunen P, Aicher L, Alessandrelli M, Bernauer U, Bleeker EAJ, Bouillard J, Di Prospero Fanghella P, Draisci R, Dusinska M, Encheva G, Flament G, Haase A, Handzhiyski Y, Herzberg F, Huwyler J, Jacobsen NR, Jeliazkov V, Jeliazkova N, Nymark P, Grafström R, Oomen AG, Polci ML, Riebeling C, Sandström J, Shivachev B, Stateva S, Tanasescu S, Tsekovska R, Wallin H, Wilks MF, Zellmer S, Apostolova MD.

Nanotoxicology. 2019 Feb;13(1):119-141. doi: 10.1080/17435390.2018.1513092. Epub 2018 Sep 5.

PMID:
30182766
4.

Physicochemical predictors of Multi-Walled Carbon Nanotube-induced pulmonary histopathology and toxicity one year after pulmonary deposition of 11 different Multi-Walled Carbon Nanotubes in mice.

Knudsen KB, Berthing T, Jackson P, Poulsen SS, Mortensen A, Jacobsen NR, Skaug V, Szarek J, Hougaard KS, Wolff H, Wallin H, Vogel U.

Basic Clin Pharmacol Toxicol. 2019 Feb;124(2):211-227. doi: 10.1111/bcpt.13119. Epub 2018 Oct 18.

PMID:
30168672
5.

Corrigendum to "MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs" [Toxicol. Appl. Pharmacol., 284 (2015) 16-32].

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2018 Sep 15;355:286. doi: 10.1016/j.taap.2018.06.006. Epub 2018 Jun 13. No abstract available.

6.

Toxicity of pristine and paint-embedded TiO2 nanomaterials.

Saber AT, Mortensen A, Szarek J, Jacobsen NR, Levin M, Koponen IK, Jensen KA, Vogel U, Wallin H.

Hum Exp Toxicol. 2019 Jan;38(1):11-24. doi: 10.1177/0960327118774910. Epub 2018 May 16.

PMID:
29766753
7.

Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles.

Hadrup N, Bengtson S, Jacobsen NR, Jackson P, Nocun M, Saber AT, Jensen KA, Wallin H, Vogel U.

Mutagenesis. 2017 Dec 31;32(6):581-597. doi: 10.1093/mutage/gex042.

8.

Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice.

Modrzynska J, Berthing T, Ravn-Haren G, Jacobsen NR, Weydahl IK, Loeschner K, Mortensen A, Saber AT, Vogel U.

Part Fibre Toxicol. 2018 Jan 3;15(1):2. doi: 10.1186/s12989-017-0238-9.

9.

Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice.

Kermanizadeh A, Jacobsen NR, Roursgaard M, Loft S, Møller P.

Heliyon. 2017 Dec 1;3(11):e00458. doi: 10.1016/j.heliyon.2017.e00458. eCollection 2017 Nov.

10.

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis.

Rahman L, Jacobsen NR, Aziz SA, Wu D, Williams A, Yauk CL, White P, Wallin H, Vogel U, Halappanavar S.

Mutat Res. 2017 Nov;823:28-44. doi: 10.1016/j.mrgentox.2017.08.005. Epub 2017 Sep 8.

11.

Weight of evidence analysis for assessing the genotoxic potential of carbon nanotubes.

Møller P, Jacobsen NR.

Crit Rev Toxicol. 2017 Nov;47(10):867-884. doi: 10.1080/10408444.2017.1367755. Epub 2017 Sep 22. Review. Erratum in: Crit Rev Toxicol. 2017 Nov;47(10):i.

PMID:
28937307
12.

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide.

Bengtson S, Knudsen KB, Kyjovska ZO, Berthing T, Skaug V, Levin M, Koponen IK, Shivayogimath A, Booth TJ, Alonso B, Pesquera A, Zurutuza A, Thomsen BL, Troelsen JT, Jacobsen NR, Vogel U.

PLoS One. 2017 Jun 1;12(6):e0178355. doi: 10.1371/journal.pone.0178355. eCollection 2017.

13.

Hepatic Hazard Assessment of Silver Nanoparticle Exposure in Healthy and Chronically Alcohol Fed Mice.

Kermanizadeh A, Jacobsen NR, Roursgaard M, Loft S, Møller P.

Toxicol Sci. 2017 Jul 1;158(1):176-187. doi: 10.1093/toxsci/kfx080.

PMID:
28453772
14.

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo.

Bornholdt J, Saber AT, Lilje B, Boyd M, Jørgensen M, Chen Y, Vitezic M, Jacobsen NR, Poulsen SS, Berthing T, Bressendorff S, Vitting-Seerup K, Andersson R, Hougaard KS, Yauk CL, Halappanavar S, Wallin H, Vogel U, Sandelin A.

ACS Nano. 2017 Apr 25;11(4):3597-3613. doi: 10.1021/acsnano.6b07533. Epub 2017 Mar 31.

PMID:
28345861
15.

Biodistribution of Carbon Nanotubes in Animal Models.

Jacobsen NR, Møller P, Clausen PA, Saber AT, Micheletti C, Jensen KA, Wallin H, Vogel U.

Basic Clin Pharmacol Toxicol. 2017 Sep;121 Suppl 3:30-43. doi: 10.1111/bcpt.12705. Epub 2017 Feb 22. Review.

16.

Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice.

Christophersen DV, Jacobsen NR, Andersen MH, Connell SP, Barfod KK, Thomsen MB, Miller MR, Duffin R, Lykkesfeldt J, Vogel U, Wallin H, Loft S, Roursgaard M, Møller P.

Toxicology. 2016 Sep 14;371:29-40. doi: 10.1016/j.tox.2016.10.003. Epub 2016 Oct 8.

17.

Surface modification does not influence the genotoxic and inflammatory effects of TiO2 nanoparticles after pulmonary exposure by instillation in mice.

Wallin H, Kyjovska ZO, Poulsen SS, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Vogel U.

Mutagenesis. 2017 Jan;32(1):47-57. doi: 10.1093/mutage/gew046. Epub 2016 Sep 22.

18.

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide.

Christophersen DV, Jacobsen NR, Jensen DM, Kermanizadeh A, Sheykhzade M, Loft S, Vogel U, Wallin H, Møller P.

PLoS One. 2016 Aug 29;11(8):e0160731. doi: 10.1371/journal.pone.0160731. eCollection 2016.

19.

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition.

Saber AT, Mortensen A, Szarek J, Koponen IK, Levin M, Jacobsen NR, Pozzebon ME, Mucelli SP, Rickerby DG, Kling K, Atluri R, Madsen AM, Jackson P, Kyjovska ZO, Vogel U, Jensen KA, Wallin H.

Part Fibre Toxicol. 2016 Jun 29;13(1):37. doi: 10.1186/s12989-016-0148-2.

20.

No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro.

Bengtson S, Kling K, Madsen AM, Noergaard AW, Jacobsen NR, Clausen PA, Alonso B, Pesquera A, Zurutuza A, Ramos R, Okuno H, Dijon J, Wallin H, Vogel U.

Environ Mol Mutagen. 2016 Jul;57(6):469-82. doi: 10.1002/em.22017. Epub 2016 May 17.

21.

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges.

Kermanizadeh A, Gosens I, MacCalman L, Johnston H, Danielsen PH, Jacobsen NR, Lenz AG, Fernandes T, Schins RP, Cassee FR, Wallin H, Kreyling W, Stoeger T, Loft S, Møller P, Tran L, Stone V.

J Toxicol Environ Health B Crit Rev. 2016;19(1):1-28. doi: 10.1080/10937404.2015.1126210. Review.

PMID:
27030582
22.

Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials.

Møller P, Christophersen DV, Jacobsen NR, Skovmand A, Gouveia AC, Andersen MH, Kermanizadeh A, Jensen DM, Danielsen PH, Roursgaard M, Jantzen K, Loft S.

Crit Rev Toxicol. 2016;46(5):437-76. doi: 10.3109/10408444.2016.1149451. Epub 2016 Mar 30. Review.

PMID:
27028752
23.

Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO2 nanoparticles.

Vranic S, Gosens I, Jacobsen NR, Jensen KA, Bokkers B, Kermanizadeh A, Stone V, Baeza-Squiban A, Cassee FR, Tran L, Boland S.

Arch Toxicol. 2017 Jan;91(1):353-363. doi: 10.1007/s00204-016-1673-3. Epub 2016 Feb 12.

PMID:
26872950
24.

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation.

Husain M, Kyjovska ZO, Bourdon-Lacombe J, Saber AT, Jensen KA, Jacobsen NR, Williams A, Wallin H, Halappanavar S, Vogel U, Yauk CL.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):573-88. doi: 10.1016/j.taap.2015.11.003. Epub 2015 Nov 10.

PMID:
26551751
25.

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories.

Jacobsen NR, Stoeger T, van den Brule S, Saber AT, Beyerle A, Vietti G, Mortensen A, Szarek J, Budtz HC, Kermanizadeh A, Banerjee A, Ercal N, Vogel U, Wallin H, Møller P.

Food Chem Toxicol. 2015 Nov;85:84-95. doi: 10.1016/j.fct.2015.08.008. Epub 2015 Aug 7.

26.

Monocyte adhesion induced by multi-walled carbon nanotubes and palmitic acid in endothelial cells and alveolar-endothelial co-cultures.

Cao Y, Roursgaard M, Jacobsen NR, Møller P, Loft S.

Nanotoxicology. 2016;10(2):235-44. doi: 10.3109/17435390.2015.1048325. Epub 2015 Jun 12.

PMID:
26067756
27.

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice.

Husain M, Wu D, Saber AT, Decan N, Jacobsen NR, Williams A, Yauk CL, Wallin H, Vogel U, Halappanavar S.

Nanotoxicology. 2015;9(8):1013-22. doi: 10.3109/17435390.2014.996192. Epub 2015 May 20.

28.

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice.

Gosens I, Kermanizadeh A, Jacobsen NR, Lenz AG, Bokkers B, de Jong WH, Krystek P, Tran L, Stone V, Wallin H, Stoeger T, Cassee FR.

PLoS One. 2015 May 12;10(5):e0126934. doi: 10.1371/journal.pone.0126934. eCollection 2015.

29.

Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans.

Jacobsen NR, Clausen PA.

Curr Probl Dermatol. 2015;48:170-5. doi: 10.1159/000369319. Epub 2015 Mar 26.

30.

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

Kyjovska ZO, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Wallin H, Vogel U.

Mutagenesis. 2015 Jul;30(4):499-507. doi: 10.1093/mutage/gev009. Epub 2015 Mar 14.

PMID:
25771385
31.

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease.

Poulsen SS, Saber AT, Mortensen A, Szarek J, Wu D, Williams A, Andersen O, Jacobsen NR, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Mar 15;283(3):210-22. doi: 10.1016/j.taap.2015.01.011. Epub 2015 Jan 22.

32.

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice.

Købler C, Poulsen SS, Saber AT, Jacobsen NR, Wallin H, Yauk CL, Halappanavar S, Vogel U, Qvortrup K, Mølhave K.

PLoS One. 2015 Jan 23;10(1):e0116481. doi: 10.1371/journal.pone.0116481. eCollection 2015.

33.

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):16-32. doi: 10.1016/j.taap.2014.12.011. Epub 2014 Dec 29. Erratum in: Toxicol Appl Pharmacol. 2018 Sep 15;355:286.

34.

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response.

Halappanavar S, Saber AT, Decan N, Jensen KA, Wu D, Jacobsen NR, Guo C, Rogowski J, Koponen IK, Levin M, Madsen AM, Atluri R, Snitka V, Birkedal RK, Rickerby D, Williams A, Wallin H, Yauk CL, Vogel U.

Environ Mol Mutagen. 2015 Mar;56(2):245-64. doi: 10.1002/em.21936. Epub 2014 Dec 11.

PMID:
25504612
35.

Role of oxidative stress in carbon nanotube-generated health effects.

Møller P, Christophersen DV, Jensen DM, Kermanizadeh A, Roursgaard M, Jacobsen NR, Hemmingsen JG, Danielsen PH, Cao Y, Jantzen K, Klingberg H, Hersoug LG, Loft S.

Arch Toxicol. 2014 Nov;88(11):1939-64. doi: 10.1007/s00204-014-1356-x. Epub 2014 Sep 12. Review.

PMID:
25212906
36.

Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals.

Møller P, Jensen DM, Christophersen DV, Kermanizadeh A, Jacobsen NR, Hemmingsen JG, Danielsen PH, Karottki DG, Roursgaard M, Cao Y, Jantzen K, Klingberg H, Hersoug LG, Loft S.

Environ Mol Mutagen. 2015 Mar;56(2):97-110. doi: 10.1002/em.21899. Epub 2014 Sep 5. Review.

PMID:
25196723
37.

DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice.

Kyjovska ZO, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Wallin H, Vogel U.

Environ Mol Mutagen. 2015 Jan;56(1):41-9. doi: 10.1002/em.21888. Epub 2014 Jul 18.

38.

Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats.

Geraets L, Oomen AG, Krystek P, Jacobsen NR, Wallin H, Laurentie M, Verharen HW, Brandon EF, de Jong WH.

Part Fibre Toxicol. 2014 Jul 3;11:30. doi: 10.1186/1743-8977-11-30.

39.

Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease.

Saber AT, Jacobsen NR, Jackson P, Poulsen SS, Kyjovska ZO, Halappanavar S, Yauk CL, Wallin H, Vogel U.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Nov-Dec;6(6):517-31. doi: 10.1002/wnan.1279. Epub 2014 Jun 12. Review.

40.

FIB-SEM imaging of carbon nanotubes in mouse lung tissue.

Købler C, Saber AT, Jacobsen NR, Wallin H, Vogel U, Qvortrup K, Mølhave K.

Anal Bioanal Chem. 2014 Jun;406(16):3863-73. doi: 10.1007/s00216-013-7566-x. Epub 2014 Jan 22.

41.

Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells.

Cao Y, Jacobsen NR, Danielsen PH, Lenz AG, Stoeger T, Loft S, Wallin H, Roursgaard M, Mikkelsen L, Møller P.

Toxicol Sci. 2014 Mar;138(1):104-16. doi: 10.1093/toxsci/kft328. Epub 2014 Jan 15.

PMID:
24431218
42.

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

Søs Poulsen S, Jacobsen NR, Labib S, Wu D, Husain M, Williams A, Bøgelund JP, Andersen O, Købler C, Mølhave K, Kyjovska ZO, Saber AT, Wallin H, Yauk CL, Vogel U, Halappanavar S.

PLoS One. 2013 Nov 19;8(11):e80452. doi: 10.1371/journal.pone.0080452. eCollection 2013.

43.

Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay.

Jackson P, Pedersen LM, Kyjovska ZO, Jacobsen NR, Saber AT, Hougaard KS, Vogel U, Wallin H.

Mutagenesis. 2013 Nov;28(6):699-707. doi: 10.1093/mutage/get049. Epub 2013 Oct 17.

44.

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression.

Bourdon JA, Saber AT, Jacobsen NR, Williams A, Vogel U, Wallin H, Halappanavar S, Yauk CL.

Cardiovasc Toxicol. 2013 Dec;13(4):406-12.

PMID:
24078381
45.

Bioaccumulation and ecotoxicity of carbon nanotubes.

Jackson P, Jacobsen NR, Baun A, Birkedal R, Kühnel D, Jensen KA, Vogel U, Wallin H.

Chem Cent J. 2013 Sep 13;7(1):154. doi: 10.1186/1752-153X-7-154.

46.

Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk.

Saber AT, Lamson JS, Jacobsen NR, Ravn-Haren G, Hougaard KS, Nyendi AN, Wahlberg P, Madsen AM, Jackson P, Wallin H, Vogel U.

PLoS One. 2013 Jul 24;8(7):e69020. doi: 10.1371/journal.pone.0069020. Print 2013.

47.
48.

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation.

Husain M, Saber AT, Guo C, Jacobsen NR, Jensen KA, Yauk CL, Williams A, Vogel U, Wallin H, Halappanavar S.

Toxicol Appl Pharmacol. 2013 Jun 15;269(3):250-62. doi: 10.1016/j.taap.2013.03.018. Epub 2013 Apr 1.

49.

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges.

Johnston H, Pojana G, Zuin S, Jacobsen NR, Møller P, Loft S, Semmler-Behnke M, McGuiness C, Balharry D, Marcomini A, Wallin H, Kreyling W, Donaldson K, Tran L, Stone V.

Crit Rev Toxicol. 2013 Jan;43(1):1-20. doi: 10.3109/10408444.2012.738187. Epub 2012 Nov 6. Review.

PMID:
23126553
50.

Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung.

Bourdon JA, Saber AT, Halappanavar S, Jackson PA, Wu D, Hougaard KS, Jacobsen NR, Williams A, Vogel U, Wallin H, Yauk CL.

Environ Mol Mutagen. 2012 Jul;53(6):462-8. doi: 10.1002/em.21706. Epub 2012 Jun 29.

PMID:
22753103

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