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Items: 1 to 50 of 78

1.

Diabetic and non-diabetic patients report equal symptom relief after arthroscopic capsular release of frozen shoulder.

Lyhne JM, Jacobsen JR, Hansen SJ, Jensen CM, Deutch SR.

J Clin Orthop Trauma. 2019 Mar-Apr;10(2):261-264. doi: 10.1016/j.jcot.2018.05.004. Epub 2018 May 19.

PMID:
30828189
2.

Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2-M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells.

Bapat A, Keita N, Martelly W, Kang P, Seet C, Jacobsen JR, Stoilov P, Hu C, Crooks GM, Sharma S.

Stem Cells. 2018 Nov;36(11):1663-1675. doi: 10.1002/stem.2885. Epub 2018 Jul 27.

3.

Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.

Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ.

Cell Rep. 2017 Aug 1;20(5):1173-1186. doi: 10.1016/j.celrep.2017.07.021.

4.

Acromioplasty in patients selected for operation by national guidelines.

Jacobsen JR, Jensen CM, Deutch SR.

J Shoulder Elbow Surg. 2017 Oct;26(10):1854-1861. doi: 10.1016/j.jse.2017.03.028. Epub 2017 Jul 5.

PMID:
28688937
5.

Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists.

Jiang L, Beattie DT, Jacobsen JR, Kintz S, Obedencio GP, Saito D, Stergiades I, Vickery RG, Long DD.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2926-2930. doi: 10.1016/j.bmcl.2017.04.092. Epub 2017 May 3.

PMID:
28499731
6.

Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.

McKinnell RM, Klein U, Linsell MS, Moran EJ, Nodwell MB, Pfeiffer JW, Thomas GR, Yu C, Jacobsen JR.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2871-6. doi: 10.1016/j.bmcl.2014.04.095. Epub 2014 May 4.

PMID:
24835980
7.

Multivalent design of long-acting β(2)-adrenoceptor agonists incorporating biarylamines.

Jacobsen JR, Aggen JB, Church TJ, Klein U, Pfeiffer JW, Pulido-Rios TM, Thomas GR, Yu C, Moran EJ.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30. doi: 10.1016/j.bmcl.2014.04.069. Epub 2014 Apr 26.

PMID:
24813741
8.

Development of an automated dual-mode supercritical fluid chromatography and reversed-phase liquid chromatography mass-directed purification system for small-molecule drug discovery.

Hettiarachchi K, Kong M, Yun A, Jacobsen JR, Xue Q.

J Sep Sci. 2014 Apr;37(7):775-81. doi: 10.1002/jssc.201301366. Epub 2014 Feb 27.

PMID:
24470330
9.

Use of a dedicated pediatric CT imaging service associated with decreased patient radiation dose.

Borders HL, Barnes CL, Parks DC, Jacobsen JR, Zhou Y, Hasselquist BE, Betz BW.

J Am Coll Radiol. 2012 May;9(5):340-3. doi: 10.1016/j.jacr.2011.12.027.

PMID:
22554632
10.

A multivalent approach to the discovery of long-acting β(2)-adrenoceptor agonists for the treatment of asthma and COPD.

Jacobsen JR, Choi SK, Combs J, Fournier EJ, Klein U, Pfeiffer JW, Thomas GR, Yu C, Moran EJ.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8. doi: 10.1016/j.bmcl.2011.11.072. Epub 2011 Nov 25.

PMID:
22178551
11.
12.

Age and gender specific pediatric reference intervals for aldolase, amylase, ceruloplasmin, creatine kinase, pancreatic amylase, prealbumin, and uric acid.

Clifford SM, Bunker AM, Jacobsen JR, Roberts WL.

Clin Chim Acta. 2011 Apr 11;412(9-10):788-90. doi: 10.1016/j.cca.2011.01.011. Epub 2011 Jan 14.

PMID:
21238443
13.

Cardiac resynchronisation therapy in paediatric and congenital heart disease: differential effects in various anatomical and functional substrates.

Janousek J, Gebauer RA, Abdul-Khaliq H, Turner M, Kornyei L, Grollmuss O, Rosenthal E, Villain E, Früh A, Paul T, Blom NA, Happonen JM, Bauersfeld U, Jacobsen JR, van den Heuvel F, Delhaas T, Papagiannis J, Trigo C; Working Group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Paediatric Cardiology.

Heart. 2009 Jul;95(14):1165-71. doi: 10.1136/hrt.2008.160465. Epub 2009 Mar 22.

14.

High frequency of submicroscopic genomic aberrations detected by tiling path array comparative genome hybridisation in patients with isolated congenital heart disease.

Erdogan F, Larsen LA, Zhang L, Tümer Z, Tommerup N, Chen W, Jacobsen JR, Schubert M, Jurkatis J, Tzschach A, Ropers HH, Ullmann R.

J Med Genet. 2008 Nov;45(11):704-9. doi: 10.1136/jmg.2008.058776. Epub 2008 Aug 19.

PMID:
18713793
15.

Screening of 99 Danish patients with congenital heart disease for GATA4 mutations.

Zhang L, Tümer Z, Jacobsen JR, Andersen PS, Tommerup N, Larsen LA.

Genet Test. 2006 Winter;10(4):277-80.

PMID:
17253934
16.

[Histiocytoid cardiomyopathy. A rare cause of ventricular tachycardia and sudden cardiac death in small children].

Aksglaede L, Graem N, Jacobsen JR.

Ugeskr Laeger. 2006 Jan 3;168(1):61-2. Danish.

PMID:
16393567
17.

Evidence for a multivalent interaction of symmetrical, N-linked, lidocaine dimers with voltage-gated Na+ channels.

Smith JA, Amagasu SM, Hembrador J, Axt S, Chang R, Church T, Gee C, Jacobsen JR, Jenkins T, Kaufman E, Mai N, Vickery RG.

Mol Pharmacol. 2006 Mar;69(3):921-31. Epub 2005 Dec 9.

PMID:
16339845
18.

Mutations in the HERG K+-ion channel: a novel link between long QT syndrome and sudden infant death syndrome.

Christiansen M, Tønder N, Larsen LA, Andersen PS, Simonsen H, Oyen N, Kanters JK, Jacobsen JR, Fosdal I, Wettrell G, Kjeldsen K.

Am J Cardiol. 2005 Feb 1;95(3):433-4.

PMID:
15670565
19.

Implantable cardioverter defibrillator in a 4-month-old infant with cardiac arrest associated with a vascular heart tumor.

Thøgersen AM, Helvind M, Jensen T, Andersen JH, Jacobsen JR, Chen X.

Pacing Clin Electrophysiol. 2001 Nov;24(11):1699-700.

PMID:
11816644
20.

Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRP1 ion channel: implications for acquired and congenital long Q-T syndrome.

Larsen LA, Andersen PS, Kanters J, Svendsen IH, Jacobsen JR, Vuust J, Wettrell G, Tranebjaerg L, Bathen J, Christiansen M.

Clin Chem. 2001 Aug;47(8):1390-5.

21.

Tolerance and specificity of polyketide synthases.

Khosla C, Gokhale RS, Jacobsen JR, Cane DE.

Annu Rev Biochem. 1999;68:219-53. Review.

PMID:
10872449
22.

Long QT syndrome with a high mortality rate caused by a novel G572R missense mutation in KCNH2.

Larsen LA, Svendsen IH, Jensen AM, Kanters JK, Andersen PS, Møller M, Sørensen SA, Sandøe E, Jacobsen JR, Vuust J, Christiansen M.

Clin Genet. 2000 Feb;57(2):125-30.

PMID:
10735633
23.

A single strand conformation polymorphism/heteroduplex (SSCP/HD) method for detection of mutations in 15 exons of the KVLQT1 gene, associated with long QT syndrome.

Larsen LA, Andersen PS, Kanters JK, Jacobsen JR, Vuust J, Christiansen M.

Clin Chim Acta. 1999 Feb;280(1-2):113-25.

PMID:
10090529
24.

Precursor-directed biosynthesis of 12-ethyl erythromycin.

Jacobsen JR, Keatinge-Clay AT, Cane DE, Khosla C.

Bioorg Med Chem. 1998 Aug;6(8):1171-7.

PMID:
9784859
25.

New directions in metabolic engineering.

Jacobsen JR, Khosla C.

Curr Opin Chem Biol. 1998 Feb;2(1):133-7. Review.

PMID:
9667907
26.

Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis.

Jacobsen JR, Cane DE, Khosla C.

Biochemistry. 1998 Apr 7;37(14):4928-34.

PMID:
9538011
27.

Relationship between cumulative anthracycline dose and late cardiotoxicity in childhood acute lymphoblastic leukemia.

Nysom K, Holm K, Lipsitz SR, Mone SM, Colan SD, Orav EJ, Sallan SE, Olsen JH, Hertz H, Jacobsen JR, Lipshultz SE.

J Clin Oncol. 1998 Feb;16(2):545-50.

PMID:
9469339
28.
29.

Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase.

Jacobsen JR, Hutchinson CR, Cane DE, Khosla C.

Science. 1997 Jul 18;277(5324):367-9.

30.

Early experience with the Norwood procedure.

Conte S, Hansen PB, Jensen T, Jacobsen JR, Helvind M, Lauridsen P, Pettersson G.

Cardiovasc Surg. 1997 Jun;5(3):315-9.

PMID:
9293368
31.

One-stage repair of truncus arteriosus, CAVC, and TAPVC.

Conte S, Jensen T, Jacobsen JR, Joyce FS, Lauridsen P, Pettersson G.

Ann Thorac Surg. 1997 Jun;63(6):1781-3.

PMID:
9205190
32.

Is the arterial switch operation still a challenge in small centers?

Conte S, Jacobsen JR, Jensen T, Hansen PB, Helvind M, Lauridsen P, Stafanger G, Pettersson G.

Eur J Cardiothorac Surg. 1997 Apr;11(4):682-6.

PMID:
9151038
33.

Double-homograft repair of truncus arteriosus with severe truncal valve dysfunction.

Conte S, Jensen T, Jacobsen JR, Larsen B, Helvind M, Lauridsen P, Pettersson G.

Scand Cardiovasc J. 1997;31(4):245-7.

PMID:
9291547
34.

A functional chimeric modular polyketide synthase generated via domain replacement.

Bedford D, Jacobsen JR, Luo G, Cane DE, Khosla C.

Chem Biol. 1996 Oct;3(10):827-31.

35.

The scope of antibody catalysis.

Jacobsen JR, Schultz PG.

Curr Opin Struct Biol. 1995 Dec;5(6):818-24. Review.

PMID:
8749371
36.

Perinatal outcome after in vitro fertilisation.

Petersen K, Hornnes PJ, Ellingsen S, Jensen F, Brocks V, Starup J, Jacobsen JR, Andersen AN.

Acta Obstet Gynecol Scand. 1995 Feb;74(2):129-31.

PMID:
7900508
37.

[Kawasaki disease. Incidence in Denmark during the period 1981-1990].

Bülow SL, Hansen US, Hansen D, Pedersen FK, Herlin T, Jacobsen JR, Dørup JG.

Ugeskr Laeger. 1994 Aug 22;156(34):4813-6. Danish.

PMID:
7992415
38.

True trisomy 15 mosaicism, detected by amniocentesis at 12 weeks of gestation and fetal echocardiography.

Sundberg K, Brocks V, Jacobsen JR, Beck B.

Prenat Diagn. 1994 Jul;14(7):559-63.

PMID:
7971757
39.

Antibody catalysis of peptide bond formation.

Jacobsen JR, Schultz PG.

Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5888-92.

40.

Fluorescence probes in biochemistry: an examination of the non-fluorescent behavior of dansylamide by photoacoustic calorimetry.

Grabowski JJ, Bertozzi CR, Jacobsen JR, Jain A, Marzluff EM, Suh AY.

Anal Biochem. 1992 Dec;207(2):214-26.

PMID:
1481973
41.

Aneurysm of the ductus arteriosus in the neonate: three case reports with a review of the literature.

Lund JT, Hansen D, Brocks V, Jensen MB, Jacobsen JR.

Pediatr Cardiol. 1992 Oct;13(4):222-6. Review.

PMID:
1518741
42.

Bacterial endocarditis in children: trends in its diagnosis, course, and prognosis.

Hansen D, Schmiegelow K, Jacobsen JR.

Pediatr Cardiol. 1992 Oct;13(4):198-203.

PMID:
1518737
43.

[Antibiotic prevention of endocarditis. A reference program for physicians and dentists].

Gutschik E, Wennevold A, Jacobsen JR, Hjelms E.

Ugeskr Laeger. 1992 Jul 6;154(28):1979-81. Danish. No abstract available.

PMID:
1509562
44.

An efficient antibody-catalyzed aminoacylation reaction.

Jacobsen JR, Prudent JR, Kochersperger L, Yonkovich S, Schultz PG.

Science. 1992 Apr 17;256(5055):365-7.

PMID:
1566082
45.

[Percutaneous pulmonary balloon valvuloplasty in Denmark].

Thuesen L, Bjerregaard P, Efsen F, Jacobsen JR, Kristensen BO, Oxhøj H, Sørensen KE, Thayssen P, Wennevold A.

Ugeskr Laeger. 1989 Oct 23;151(43):2789-91. Danish.

PMID:
2588355
46.

[Prenatal detection of congenital heart disease].

Sørensen K, Brocks V, Jacobsen JR.

Ugeskr Laeger. 1989 Sep 25;151(39):2498-500. Danish.

PMID:
2800027
47.

[In vitro fertilization and embryo transfer. 2. The first 44 deliveries of 55 infants].

Petersen K, Brocks V, Jensen FR, Jacobsen JR, Paulin J, Andersen CY, Starup J.

Ugeskr Laeger. 1989 May 8;151(19):1175-8. Danish.

PMID:
2734891
48.

[Pulmonary hypertension in children treated with ventriculo-atrial shunt in hydrocephalus].

Pryds OA, Petersen SA, Jacobsen JR, Gjerris F.

Ugeskr Laeger. 1989 Feb 27;151(9):570-2. Danish.

PMID:
2922869
49.

[Fetal arrhythmias. Diagnosis and clinical significance].

Brocks V, Nickelsen C, Jacobsen JR, Bock JE.

Ugeskr Laeger. 1988 Apr 11;150(15):900-3. Review. Danish. No abstract available.

PMID:
3284131
50.

[Fetal bradycardia in the 29th week of pregnancy. A sequel to hypoxia or genuine arrhythmia?].

Nickelsen C, Brocks V, Jacobsen JR, Bock JE.

Ugeskr Laeger. 1988 Feb 22;150(8):491-2. Danish. No abstract available.

PMID:
3354107

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