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Items: 1 to 50 of 938

1.

Encoding Clinical Data with the Human Phenotype Ontology for Computational Differential Diagnostics.

Köhler S, Øien NC, Buske OJ, Groza T, Jacobsen JOB, McNamara C, Vasilevsky N, Carmody LC, Gourdine JP, Gargano M, McMurry JA, Danis D, Mungall CJ, Smedley D, Haendel M, Robinson PN.

Curr Protoc Hum Genet. 2019 Sep;103(1):e92. doi: 10.1002/cphg.92.

PMID:
31479590
2.

Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging.

Clitherow KH, Murdoch C, Spain SG, Handler AM, Colley HE, Stie MB, Mørck Nielsen H, Janfelt C, Hatton PV, Jacobsen J.

Mol Pharm. 2019 Sep 3;16(9):3948-3956. doi: 10.1021/acs.molpharmaceut.9b00535. Epub 2019 Aug 15.

PMID:
31361498
3.

Observation of nonscalar and logarithmic correlations in two- and three-dimensional percolation.

Tan X, Couvreur R, Deng Y, Jacobsen JL.

Phys Rev E. 2019 May;99(5-1):050103. doi: 10.1103/PhysRevE.99.050103.

PMID:
31212414
4.

Presence and genetic variability of Piscine orthoreovirus genotype 1 (PRV-1) in wild salmonids in Northern Europe and North Atlantic Ocean.

Vendramin N, Cuenca A, Sørensen J, Alencar ALF, Christiansen DH, Jacobsen JA, Axen C, Lieffrig F, Ruane NM, Martin P, Sheehan T, Iburg TM, Rimstad E, Olesen NJ.

J Fish Dis. 2019 Aug;42(8):1107-1118. doi: 10.1111/jfd.13025. Epub 2019 May 28.

PMID:
31140193
5.

The first water-based synthesis of Ce(iv)-MOFs with saturated chiral and achiral C4-dicarboxylate linkers.

Jacobsen J, Achenbach B, Reinsch H, Smolders S, Lange FD, Friedrichs G, De Vos D, Stock N.

Dalton Trans. 2019 Jun 21;48(23):8433-8441. doi: 10.1039/c9dt01542f. Epub 2019 May 22.

PMID:
31116214
6.

Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression.

Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG.

Gastroenterology. 2019 Aug;157(2):507-521.e4. doi: 10.1053/j.gastro.2019.04.022. Epub 2019 May 7.

PMID:
31071306
7.

Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.

Jacobsen JPR, Oh A, Bangle R, Roberts WL, Royer EL, Modesto N, Windermere SA, Yi Z, Vernon R, Cajina M, Urs NM, Snyder JC, Nicholls PJ, Sachs BD, Caron MG.

Neuropsychopharmacology. 2019 Apr 29. doi: 10.1038/s41386-019-0400-1. [Epub ahead of print]

PMID:
31035282
8.

Acids 'generally recognized as safe' affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers.

Stie MB, Jones M, Sørensen HO, Jacobsen J, Chronakis IS, Nielsen HM.

Carbohydr Polym. 2019 Jul 1;215:253-262. doi: 10.1016/j.carbpol.2019.03.061. Epub 2019 Mar 18.

PMID:
30981352
9.

Evaluation of the performance of copy number variant prediction tools for the detection of deletions from whole genome sequencing data.

Whitford W, Lehnert K, Snell RG, Jacobsen JC.

J Biomed Inform. 2019 Jun;94:103174. doi: 10.1016/j.jbi.2019.103174. Epub 2019 Apr 6. Review.

PMID:
30965134
10.

Polymeric Lids for Microcontainers for Oral Protein Delivery.

Mazzoni C, Jacobsen RD, Mortensen J, Jørgensen JR, Vaut L, Jacobsen J, Gundlach C, Müllertz A, Nielsen LH, Boisen A.

Macromol Biosci. 2019 May;19(5):e1900004. doi: 10.1002/mabi.201900004. Epub 2019 Apr 2.

PMID:
30938933
11.

Hypermobility among patients with greater trochanteric pain syndrome.

Reimer LCU, Jacobsen JS, Mechlenburg I.

Dan Med J. 2019 Apr;66(4). pii: A5539.

PMID:
30910004
12.

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial.

Rosenstock J, Allison D, Birkenfeld AL, Blicher TM, Deenadayalan S, Jacobsen JB, Serusclat P, Violante R, Watada H, Davies M; PIONEER 3 Investigators.

JAMA. 2019 Apr 16;321(15):1466-1480. doi: 10.1001/jama.2019.2942.

PMID:
30903796
13.

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, Valence S, Buratti J, Fagerberg CR, Soerensen KP, Kibaek M, Kamsteeg EJ, Koolen DA, Gunning B, Schelhaas HJ, Kruer MC, Fox J, Bakhtiari S, Jarrar R, Padilla-Lopez S, Lindstrom K, Jin SC, Zeng X, Bilguvar K, Papavasileiou A, Xing Q, Zhu C, Boysen K, Vairo F, Lanpher BC, Klee EW, Tillema JM, Payne ET, Cousin MA, Kruisselbrink TM, Wick MJ, Baker J, Haan E, Smith N, Sadeghpour A, Davis EE, Katsanis N; Task Force for Neonatal Genomics, Corbett MA, MacLennan AH, Gecz J, Biskup S, Goldmann E, Rodan LH, Kichula E, Segal E, Jackson KE, Asamoah A, Dimmock D, McCarrier J, Botto LD, Filloux F, Tvrdik T, Cascino GD, Klingerman S, Neumann C, Wang R, Jacobsen JC, Nolan MA, Snell RG, Lehnert K, Sadleir LG, Anderlid BM, Kvarnung M, Guerrini R, Friez MJ, Lyons MJ, Leonhard J, Kringlen G, Casas K, El Achkar CM, Smith LA, Rotenberg A, Poduri A, Sanchis-Juan A, Carss KJ, Rankin J, Zeman A, Raymond FL, Blyth M, Kerr B, Ruiz K, Urquhart J, Hughes I, Banka S; Deciphering Developmental Disorders Study, Hedrich UBS, Scheffer IE, Helbig I, Zamponi GW, Lerche H, Mefford HC.

Am J Hum Genet. 2019 Mar 7;104(3):562. doi: 10.1016/j.ajhg.2019.02.015. No abstract available.

14.

Roads and livelihood activity choices in the Greater Serengeti Ecosystem, Tanzania.

Walelign SZ, Nielsen MR, Jacobsen JB.

PLoS One. 2019 Mar 8;14(3):e0213089. doi: 10.1371/journal.pone.0213089. eCollection 2019.

15.

Diabetic and non-diabetic patients report equal symptom relief after arthroscopic capsular release of frozen shoulder.

Lyhne JM, Jacobsen JR, Hansen SJ, Jensen CM, Deutch SR.

J Clin Orthop Trauma. 2019 Mar-Apr;10(2):261-264. doi: 10.1016/j.jcot.2018.05.004. Epub 2018 May 19.

PMID:
30828189
16.

To Prepare Patients Better: Reimagining Advance Care Planning.

Rosenberg LB, Greenwald JL, Jacobsen JC.

Am Fam Physician. 2019 Mar 1;99(5):278-280. No abstract available.

PMID:
30811161
17.

The Surprise Question Can Be Used to Identify Heart Failure Patients in the Emergency Department Who Would Benefit From Palliative Care.

Aaronson EL, George N, Ouchi K, Zheng H, Bowman J, Monette D, Jacobsen J, Jackson V.

J Pain Symptom Manage. 2019 May;57(5):944-951. doi: 10.1016/j.jpainsymman.2019.02.007. Epub 2019 Feb 16.

PMID:
30776539
18.

Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules.

Andersen TK, Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Fauskanger M, Tveita AA, Grødeland G, Bogen B.

NPJ Vaccines. 2019 Feb 11;4:9. doi: 10.1038/s41541-019-0101-0. eCollection 2019.

19.

Patient-reported outcome and muscle-tendon pain after periacetabular osteotomy are related: 1-year follow-up in 82 patients with hip dysplasia.

Jacobsen JS, Søballe K, Thorborg K, Bolvig L, Storgaard Jakobsen S, Hölmich P, Mechlenburg I.

Acta Orthop. 2019 Feb;90(1):40-45. doi: 10.1080/17453674.2018.1555637.

20.

Anaesthetic efficacy of Aqui-S, Benzoak, and MS-222 on lumpfish (Cyclopterus lumpus) fries. Impact from temperature, salinity, and fasting.

Jacobsen JV, Steen K, Nilssen KJ.

PLoS One. 2019 Jan 22;14(1):e0211080. doi: 10.1371/journal.pone.0211080. eCollection 2019.

21.

Utilising portfolio theory in environmental research - New perspectives and considerations.

Matthies BD, Jacobsen JB, Knoke T, Paul C, Valsta L.

J Environ Manage. 2019 Feb 1;231:926-939. doi: 10.1016/j.jenvman.2018.10.049. Epub 2018 Nov 16.

PMID:
30602254
22.

Exact Stoichiometry of Ce xZr6- x Cornerstones in Mixed-Metal UiO-66 Metal-Organic Frameworks Revealed by Extended X-ray Absorption Fine Structure Spectroscopy.

Lomachenko KA, Jacobsen J, Bugaev AL, Atzori C, Bonino F, Bordiga S, Stock N, Lamberti C.

J Am Chem Soc. 2018 Dec 19;140(50):17379-17383. doi: 10.1021/jacs.8b10343. Epub 2018 Dec 7.

PMID:
30497258
23.

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.

Köhler S, Carmody L, Vasilevsky N, Jacobsen JOB, Danis D, Gourdine JP, Gargano M, Harris NL, Matentzoglu N, McMurry JA, Osumi-Sutherland D, Cipriani V, Balhoff JP, Conlin T, Blau H, Baynam G, Palmer R, Gratian D, Dawkins H, Segal M, Jansen AC, Muaz A, Chang WH, Bergerson J, Laulederkind SJF, Yüksel Z, Beltran S, Freeman AF, Sergouniotis PI, Durkin D, Storm AL, Hanauer M, Brudno M, Bello SM, Sincan M, Rageth K, Wheeler MT, Oegema R, Lourghi H, Della Rocca MG, Thompson R, Castellanos F, Priest J, Cunningham-Rundles C, Hegde A, Lovering RC, Hajek C, Olry A, Notarangelo L, Similuk M, Zhang XA, Gómez-Andrés D, Lochmüller H, Dollfus H, Rosenzweig S, Marwaha S, Rath A, Sullivan K, Smith C, Milner JD, Leroux D, Boerkoel CF, Klion A, Carter MC, Groza T, Smedley D, Haendel MA, Mungall C, Robinson PN.

Nucleic Acids Res. 2019 Jan 8;47(D1):D1018-D1027. doi: 10.1093/nar/gky1105.

24.

The LASSO Program in Oslo: Harm Reduction Using Buprenorphine-Naloxone (Suboxone®) in a Low Threshold Setting.

Henriksen K, Jacobsen JA, Henriksen EM, Gomes L, Waal H, Krajci P.

Eur Addict Res. 2018;24(6):286-292. doi: 10.1159/000495188. Epub 2018 Nov 22.

PMID:
30466108
25.

Softening Our Approach to Discussing Prognosis.

Lakin JR, Jacobsen J.

JAMA Intern Med. 2019 Jan 1;179(1):5-6. doi: 10.1001/jamainternmed.2018.5786. No abstract available.

PMID:
30453318
26.

Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery.

Handler AM, Marxen E, Jacobsen J, Janfelt C.

Eur J Pharm Sci. 2019 Jan 15;127:276-281. doi: 10.1016/j.ejps.2018.11.011. Epub 2018 Nov 12.

PMID:
30439495
27.

Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa.

Hansen SE, Marxen E, Janfelt C, Jacobsen J.

Eur J Pharm Biopharm. 2018 Dec;133:250-257. doi: 10.1016/j.ejpb.2018.10.016. Epub 2018 Oct 22.

PMID:
30359717
28.

Communication Differences between Oncologists and Palliative Care Clinicians: A Qualitative Analysis of Early, Integrated Palliative Care in Patients with Advanced Cancer.

Thomas TH, Jackson VA, Carlson H, Rinaldi S, Sousa A, Hansen A, Kamdar M, Jacobsen J, Park ER, Pirl WF, Temel JS, Greer JA.

J Palliat Med. 2019 Jan;22(1):41-49. doi: 10.1089/jpm.2018.0092. Epub 2018 Oct 25.

PMID:
30359204
29.

Penetrance and expressivity of the R858H CACNA1C variant in a five-generation pedigree segregating an arrhythmogenic channelopathy.

Gardner RJM, Crozier IG, Binfield AL, Love DR, Lehnert K, Gibson K, Lintott CJ, Snell RG, Jacobsen JC, Jones PP, Waddell-Smith KE, Kennedy MA, Skinner JR.

Mol Genet Genomic Med. 2019 Jan;7(1):e00476. doi: 10.1002/mgg3.476. Epub 2018 Oct 21.

30.

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, Valence S, Buratti J, Fagerberg CR, Soerensen KP, Kibaek M, Kamsteeg EJ, Koolen DA, Gunning B, Schelhaas HJ, Kruer MC, Fox J, Bakhtiari S, Jarrar R, Padilla-Lopez S, Lindstrom K, Jin SC, Zeng X, Bilguvar K, Papavasileiou A, Xing Q, Zhu C, Boysen K, Vairo F, Lanpher BC, Klee EW, Tillema JM, Payne ET, Cousin MA, Kruisselbrink TM, Wick MJ, Baker J, Haan E, Smith N, Sadeghpour A, Davis EE, Katsanis N; Task Force for Neonatal Genomics, Corbett MA, MacLennan AH, Gecz J, Biskup S, Goldmann E, Rodan LH, Kichula E, Segal E, Jackson KE, Asamoah A, Dimmock D, McCarrier J, Botto LD, Filloux F, Tvrdik T, Cascino GD, Klingerman S, Neumann C, Wang R, Jacobsen JC, Nolan MA, Snell RG, Lehnert K, Sadleir LG, Anderlid BM, Kvarnung M, Guerrini R, Friez MJ, Lyons MJ, Leonhard J, Kringlen G, Casas K, El Achkar CM, Smith LA, Rotenberg A, Poduri A, Sanchis-Juan A, Carss KJ, Rankin J, Zeman A, Raymond FL, Blyth M, Kerr B, Ruiz K, Urquhart J, Hughes I, Banka S; Deciphering Developmental Disorders Study, Hedrich UBS, Scheffer IE, Helbig I, Zamponi GW, Lerche H, Mefford HC.

Am J Hum Genet. 2018 Nov 1;103(5):666-678. doi: 10.1016/j.ajhg.2018.09.006. Epub 2018 Oct 18. Erratum in: Am J Hum Genet. 2019 Mar 7;104(3):562.

31.

Analytical aspects of printed oral dosage forms.

Edinger M, Jacobsen J, Bar-Shalom D, Rantanen J, Genina N.

Int J Pharm. 2018 Dec 20;553(1-2):97-108. doi: 10.1016/j.ijpharm.2018.10.030. Epub 2018 Oct 11. Review.

PMID:
30316794
32.

Modelling brain dopamine-serotonin vesicular transport disease in Caenorhabditis elegans.

Young AT, Ly KN, Wilson C, Lehnert K, Snell RG, Reid SJ, Jacobsen JC.

Dis Model Mech. 2018 Nov 9;11(11). pii: dmm035709. doi: 10.1242/dmm.035709.

33.

Systematic Investigations of the Transition between Framework Topologies in Ce/Zr-MOFs.

Jacobsen J, Reinsch H, Stock N.

Inorg Chem. 2018 Oct 15;57(20):12820-12826. doi: 10.1021/acs.inorgchem.8b02019. Epub 2018 Sep 26.

PMID:
30256108
34.

LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial.

Game F, Jeffcoate W, Tarnow L, Jacobsen JL, Whitham DJ, Harrison EF, Ellender SJ, Fitzsimmons D, Löndahl M; LeucoPatch II trial team.

Lancet Diabetes Endocrinol. 2018 Nov;6(11):870-878. doi: 10.1016/S2213-8587(18)30240-7. Epub 2018 Sep 19.

PMID:
30243803
35.

matchbox: An open-source tool for patient matching via the Matchmaker Exchange.

Arachchi H, Wojcik MH, Weisburd B, Jacobsen JOB, Valkanas E, Baxter S, Byrne AB, O'Donnell-Luria AH, Haendel M, Smedley D, MacArthur DG, Philippakis AA, Rehm HL.

Hum Mutat. 2018 Dec;39(12):1827-1834. doi: 10.1002/humu.23655. Epub 2018 Oct 3.

PMID:
30240502
36.

Stimulation history affects vasomotor responses in rat mesenteric arterioles.

Hald BO, Sørensen RB, Sørensen PG, Sørensen CM, Jacobsen JCB.

Pflugers Arch. 2019 Feb;471(2):271-283. doi: 10.1007/s00424-018-2206-0. Epub 2018 Sep 15.

PMID:
30219946
37.

Shed-MEDS: pilot of a patient-centered deprescribing framework reduces medications in hospitalized older adults being transferred to inpatient postacute care.

Petersen AW, Shah AS, Simmons SF, Shotwell MS, Jacobsen JML, Myers AP, Mixon AS, Bell SP, Kripalani S, Schnelle JF, Vasilevskis EE.

Ther Adv Drug Saf. 2018 Jun 15;9(9):523-533. doi: 10.1177/2042098618781524. eCollection 2018 Sep.

38.

One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation.

Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD.

J Exp Med. 2018 Oct 1;215(10):2686-2695. doi: 10.1084/jem.20172064. Epub 2018 Sep 4.

39.

Progressive resistance training in patients with hip dysplasia: A feasibility study.

Mortensen L, Schultz J, Elsner A, Jakobsen SS, Søballe K, Jacobsen JS, Kierkegaard S, Dalgas U, Mechlenburg I.

J Rehabil Med. 2018 Aug 22;50(8):751-758. doi: 10.2340/16501977-2371.

40.

Genomic medicine must reduce, not compound, health inequities: the case for hauora-enhancing genomic resources for New Zealand.

Robertson SP, Hindmarsh JH, Berry S, Cameron VA, Cox MP, Dewes O, Doughty RN, Gray G, Jacobsen JC, Laurence A, Matisoo-Smith E, Morton S, Shelling AN, Sika-Paotonu D, Rolleston A, Skinner JR, Snell RG, Sporle A, Print C, Merriman TR, Hudson M, Wilcox P.

N Z Med J. 2018 Aug 17;131(1480):81-89.

PMID:
30116069
41.

Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2-M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells.

Bapat A, Keita N, Martelly W, Kang P, Seet C, Jacobsen JR, Stoilov P, Hu C, Crooks GM, Sharma S.

Stem Cells. 2018 Nov;36(11):1663-1675. doi: 10.1002/stem.2885. Epub 2018 Jul 27.

42.

Not Your Grandma's Advance Care Planning: Preparing (Ourselves) for a Systems-Based Approach.

Jacobsen J.

J Palliat Med. 2018 Jul;21(7):893-894. doi: 10.1089/jpm.2018.0099. No abstract available.

PMID:
29975611
43.

No QTc Prolongation with Semaglutide: A Thorough QT Study in Healthy Subjects.

Demmel V, Sandberg-Schaal A, Jacobsen JB, Golor G, Pettersson J, Flint A.

Diabetes Ther. 2018 Aug;9(4):1441-1456. doi: 10.1007/s13300-018-0442-0. Epub 2018 May 24.

44.

Lack of tone in mouse small mesenteric arteries leads to outward remodeling, which can be prevented by prolonged agonist-induced vasoconstriction.

Klein A, Joseph PD, Christensen VG, Jensen LJ, Jacobsen JCB.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H644-H657. doi: 10.1152/ajpheart.00111.2018. Epub 2018 May 18.

45.

Duality and the universality class of the three-state Potts antiferromagnet on plane quadrangulations.

Lv JP, Deng Y, Jacobsen JL, Salas J, Sokal AD.

Phys Rev E. 2018 Apr;97(4-1):040104. doi: 10.1103/PhysRevE.97.040104.

PMID:
29758740
46.

A Pivotal Field Study to Support the Registration of Levothyroxine Sodium Tablets for Canine Hypothyroidism.

Lewis VA, Morrow CMK, Jacobsen JA, Lloyd WE.

J Am Anim Hosp Assoc. 2018 Jul/Aug;54(4):201-208. doi: 10.5326/JAAHA-MS-6649. Epub 2018 May 14.

PMID:
29757661
47.

Isokinetic dynamometry and gait analysis reveal different hip joint status in patients with hip dysplasia.

Sørensen H, Nielsen DB, Jacobsen JS, Søballe K, Mechlenburg I.

Hip Int. 2019 Mar;29(2):215-221. doi: 10.1177/1120700018773401. Epub 2018 May 9.

PMID:
29739283
48.

Promoting biodiversity values of small forest patches in agricultural landscapes: Ecological drivers and social demand.

Varela E, Verheyen K, Valdés A, Soliño M, Jacobsen JB, De Smedt P, Ehrmann S, Gärtner S, Górriz E, Decocq G.

Sci Total Environ. 2018 Apr 1;619-620:1319-1329. doi: 10.1016/j.scitotenv.2017.11.190. Epub 2017 Nov 23.

PMID:
29734609
49.

Muscle-tendon-related abnormalities detected by ultrasonography are common in symptomatic hip dysplasia.

Jacobsen JS, Bolvig L, Hölmich P, Thorborg K, Jakobsen SS, Søballe K, Mechlenburg I.

Arch Orthop Trauma Surg. 2018 Aug;138(8):1059-1067. doi: 10.1007/s00402-018-2947-4. Epub 2018 May 4.

PMID:
29728835
50.

Contingent valuation of health and mood impacts of PM2.5 in Beijing, China.

Yin H, Pizzol M, Jacobsen JB, Xu L.

Sci Total Environ. 2018 Jul 15;630:1269-1282. doi: 10.1016/j.scitotenv.2018.02.275. Epub 2018 Mar 7.

PMID:
29554748

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