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Items: 1 to 50 of 498

1.

Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent.

Barnes MD, Kumar V, Bethel CR, Moussa SH, O'Donnell J, Rutter JD, Good CE, Hujer KM, Hujer AM, Marshall SH, Kreiswirth BN, Richter SS, Rather PN, Jacobs MR, Papp-Wallace KM, van den Akker F, Bonomo RA.

MBio. 2019 Mar 12;10(2). pii: e00159-19. doi: 10.1128/mBio.00159-19.

2.

Beyond piperacillin-tazobactam: cefepime and AAI101 as a potent β-lactam-β-lactamase inhibitor combination.

Papp-Wallace KM, Bethel CR, Caillon J, Barnes MD, Potel G, Bajaksouzian S, Rutter JD, Reghal A, Shapiro S, Taracila MA, Jacobs MR, Bonomo RA, Jacqueline C.

Antimicrob Agents Chemother. 2019 Mar 11. pii: AAC.00105-19. doi: 10.1128/AAC.00105-19. [Epub ahead of print]

PMID:
30858223
3.

Symptoms of anxiety and depression and use of anxiolytic-hypnotics and antidepressants in current and former smokers with and without COPD - A cross sectional analysis of the COPDGene cohort.

Iyer AS, Holm KE, Bhatt SP, Kim V, Kinney GL, Wamboldt FS, Jacobs MR, Regan EA, Armstrong HF, Lowe KE, Martinez CH, Dransfield MT, Foreman MG, Shinozaki G, Hanania NA, Wise RA, Make BJ, Hoth KF; COPDGene Investigators.

J Psychosom Res. 2019 Mar;118:18-26. doi: 10.1016/j.jpsychores.2019.01.002. Epub 2019 Jan 7.

PMID:
30782350
4.

Effects of Roflumilast on Rehospitalization and Mortality in Patients.

Criner GJ, Jacobs MR, Zhao H, Marchetti N.

Chronic Obstr Pulm Dis. 2018 Dec 20;6(1):74-85. doi: 10.15326/jcopdf.6.1.2018.0139.

5.

Effect of Lung Volume Reduction Surgery on Respiratory Muscle Strength in Advanced Emphysema.

Criner RN, Yu D, Jacobs MR, Criner GJ.

Chronic Obstr Pulm Dis. 2018 Oct 12;6(1):40-50. doi: 10.15326/jcopdf.6.1.2018.0188.

6.

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases.

Jacobs MR, Abdelhamed AM, Good CE, Rhoads DD, Hujer KM, Hujer AM, Domitrovic TN, Rudin SD, Richter SS, van Duin D, Kreiswirth BN, Greco C, Fouts DE, Bonomo RA.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01801-18. doi: 10.1128/AAC.01801-18. Print 2019 Jan.

PMID:
30323050
7.

Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam against Pseudomonas aeruginosa: PRIMERS IV.

Evans SR, Tran TTT, Hujer AM, Hill CB, Hujer KM, Mediavilla JR, Manca C, Domitrovic TN, Perez F, Farmer M, Pitzer KM, Wilson BM, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Fowler VG Jr, Chambers HF, Bonomo RA; Antibacterial Resistance Leadership Group (ARLG).

Clin Infect Dis. 2018 Sep 20. doi: 10.1093/cid/ciy801. [Epub ahead of print]

PMID:
30239599
8.

Emergence of Resistance to Colistin During the Treatment of Bloodstream Infection Caused by Klebsiella pneumoniae Carbapenemase-Producing Klebsiella pneumoniae.

Kanwar A, Marshall SH, Perez F, Tomas M, Jacobs MR, Hujer AM, Domitrovic TN, Rudin SD, Rojas LJ, Kreiswirth BN, Chen L, Quinones-Mateu M, van Duin D, Bonomo RA; Antibacterial Resistance Leadership Group.

Open Forum Infect Dis. 2018 Apr 23;5(4):ofy054. doi: 10.1093/ofid/ofy054. eCollection 2018 Apr.

9.

Mycobactericidal activity of bedaquiline plus rifabutin or rifampin in ex vivo whole blood cultures of healthy volunteers: A randomized controlled trial.

Wallis RS, Good CE, O'Riordan MA, Blumer JL, Jacobs MR, Griffiss JM, Healan A, Salata RA.

PLoS One. 2018 May 2;13(5):e0196756. doi: 10.1371/journal.pone.0196756. eCollection 2018.

10.

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.

Papp-Wallace KM, Nguyen NQ, Jacobs MR, Bethel CR, Barnes MD, Kumar V, Bajaksouzian S, Rudin SD, Rather PN, Bhavsar S, Ravikumar T, Deshpande PK, Patil V, Yeole R, Bhagwat SS, Patel MV, van den Akker F, Bonomo RA.

J Med Chem. 2018 May 10;61(9):4067-4086. doi: 10.1021/acs.jmedchem.8b00091. Epub 2018 Apr 20.

PMID:
29627985
11.

Effect of alcohol-based hand rub on hand microbiome and hand skin health in hospitalized adult stem cell transplant patients: A pilot study.

Mukherjee PK, Chandra J, Retuerto M, Arters KA, Consolo MC, Patterson A, Bajaksouzian S, Arbogast JW, Cartner TJ, Jacobs MR, Ghannoum MA, Salata RA.

J Am Acad Dermatol. 2018 Jun;78(6):1218-1221.e5. doi: 10.1016/j.jaad.2017.11.046. Epub 2017 Dec 1. No abstract available.

PMID:
29203437
12.

Enlargement of the WHO international repository for platelet transfusion-relevant bacteria reference strains.

Spindler-Raffel E, Benjamin RJ, McDonald CP, Ramirez-Arcos S, Aplin K, Bekeredjian-Ding I, de Korte D, Gabriel C, Gathof B, Hanschmann KM, Hourfar K, Ingram C, Jacobs MR, Keil SD, Kou Y, Lambrecht B, Marcelis J, Mukhtar Z, Nagumo H, Niekerk T, Rojo J, Marschner S, Satake M, Seltsam A, Seifried E, Sharafat S, Störmer M, Süßner S, Wagner SJ, Yomtovian R; ISBT Working Party Transfusion-Transmitted Infectious Diseases (WP-TTID), Subgroup on Bacteria.

Vox Sang. 2017 Nov;112(8):713-722. doi: 10.1111/vox.12548. Epub 2017 Sep 27.

PMID:
28960367
13.

Nosocomial Outbreak of Extensively Drug-Resistant Acinetobacter baumannii Isolates Containing blaOXA-237 Carried on a Plasmid.

Hujer AM, Higgins PG, Rudin SD, Buser GL, Marshall SH, Xanthopoulou K, Seifert H, Rojas LJ, Domitrovic TN, Cassidy PM, Cunningham MC, Vega R, Furuno JP, Pfeiffer CD, Beldavs ZG, Wright MS, Jacobs MR, Adams MD, Bonomo RA.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00797-17. doi: 10.1128/AAC.00797-17. Print 2017 Nov.

14.

Failure to Communicate: Transmission of Extensively Drug-Resistant bla OXA-237-Containing Acinetobacter baumannii-Multiple Facilities in Oregon, 2012-2014.

Buser GL, Cassidy PM, Cunningham MC, Rudin S, Hujer AM, Vega R, Furuno JP, Marshall SH, Higgins PG, Jacobs MR, Wright MS, Adams MD, Bonomo RA, Pfeiffer CD, Beldavs ZG.

Infect Control Hosp Epidemiol. 2017 Nov;38(11):1335-1341. doi: 10.1017/ice.2017.189. Epub 2017 Sep 5.

15.

Avibactam Restores the Susceptibility of Clinical Isolates of Stenotrophomonas maltophilia to Aztreonam.

Mojica MF, Papp-Wallace KM, Taracila MA, Barnes MD, Rutter JD, Jacobs MR, LiPuma JJ, Walsh TJ, Vila AJ, Bonomo RA.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00777-17. doi: 10.1128/AAC.00777-17. Print 2017 Oct.

16.

The negative secondary test for bacterial contamination: reducing the risk of septic transfusion reactions from platelets.

Tomasulo PA, Jacobs MR.

Transfusion. 2017 Aug;57(8):2054-2055. doi: 10.1111/trf.14221. Epub 2017 Jun 27. No abstract available.

PMID:
28656692
17.

Multicenter Clinical Evaluation of BacT/Alert Virtuo Blood Culture System.

Jacobs MR, Mazzulli T, Hazen KC, Good CE, Abdelhamed AM, Lo P, Shum B, Roman KP, Robinson DC.

J Clin Microbiol. 2017 Aug;55(8):2413-2421. doi: 10.1128/JCM.00307-17. Epub 2017 May 24.

18.

Correction for Evans et al., "Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III".

Evans SR, Hujer AM, Jiang H, Hill CB, Hujer KM, Mediavilla JR, Manca C, Tran TTT, Domitrovic TN, Higgins PG, Seifert H, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Sampath R, Hall T, Marzan C, Fowler VG Jr, Chambers HF, Bonomo RA.

J Clin Microbiol. 2017 Jun;55(6):1970. doi: 10.1128/JCM.00525-17. No abstract available.

19.

Probing skin physiology through the volatile footprint: Discriminating volatile emissions before and after acute barrier disruption.

Duffy E, Jacobs MR, Kirby B, Morrin A.

Exp Dermatol. 2017 Oct;26(10):919-925. doi: 10.1111/exd.13344. Epub 2017 Jul 3.

PMID:
28370710
20.

Correction: Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial.

Wise RA, Holbrook JT, Criner G, Sethi S, Rayapudi S, Sudini KR, Sugar EA, Burke A, Thimmulappa R, Singh A, Talalay P, Fahey JW, Berenson CS, Jacobs MR, Biswal S; Broccoli Sprout Extract Trial Research Group.

PLoS One. 2017 Mar 28;12(3):e0175077. doi: 10.1371/journal.pone.0175077. eCollection 2017.

21.

Transcriptome Remodeling of Acinetobacter baumannii during Infection and Treatment.

Wright MS, Jacobs MR, Bonomo RA, Adams MD.

MBio. 2017 Mar 7;8(2). pii: e02193-16. doi: 10.1128/mBio.02193-16.

22.

Multicenter Clinical and Molecular Epidemiological Analysis of Bacteremia Due to Carbapenem-Resistant Enterobacteriaceae (CRE) in the CRE Epicenter of the United States.

Satlin MJ, Chen L, Patel G, Gomez-Simmonds A, Weston G, Kim AC, Seo SK, Rosenthal ME, Sperber SJ, Jenkins SG, Hamula CL, Uhlemann AC, Levi MH, Fries BC, Tang YW, Juretschko S, Rojtman AD, Hong T, Mathema B, Jacobs MR, Walsh TJ, Bonomo RA, Kreiswirth BN.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02349-16. doi: 10.1128/AAC.02349-16. Print 2017 Apr.

23.

Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG Jr, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02243-16. doi: 10.1128/AAC.02243-16. Print 2017 Apr.

24.

Bacterial Colonization and Antibiotic Resistance in a Prospective Cohort of Newborn Infants During the First Year of Life.

Meropol SB, Stange KC, Jacobs MR, Weiss JK, Bajaksouzian S, Bonomo RA.

Open Forum Infect Dis. 2016 Dec 5;3(4):ofw221. eCollection 2016 Oct. Erratum in: Open Forum Infect Dis. 2017 Jun 17;4(2):ofx114.

25.

Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial.

Wise RA, Holbrook JT, Criner G, Sethi S, Rayapudi S, Sudini KR, Sugar EA, Burke A, Thimmulappa R, Singh A, Talalay P, Fahey JW, Berenson CS, Jacobs MR, Biswal S; Broccoli Sprout Extract Trial Research Group.

PLoS One. 2016 Nov 10;11(11):e0163716. doi: 10.1371/journal.pone.0163716. eCollection 2016. Erratum in: PLoS One. 2017 Mar 28;12 (3):e0175077.

26.

Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III.

Evans SR, Hujer AM, Jiang H, Hill CB, Hujer KM, Mediavilla JR, Manca C, Tran TT, Domitrovic TN, Higgins PG, Seifert H, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Sampath R, Hall T, Marzan C, Fowler VG Jr, Chambers HF, Bonomo RA.

J Clin Microbiol. 2016 Dec 28;55(1):134-144. doi: 10.1128/JCM.01524-16. Print 2017 Jan. Erratum in: J Clin Microbiol. 2017 Jun;55(6):1970.

27.

Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs.

Guzzo MB, Nguyen HT, Pham TH, Wyszczelska-Rokiel M, Jakubowski H, Wolff KA, Ogwang S, Timpona JL, Gogula S, Jacobs MR, Ruetz M, Kräutler B, Jacobsen DW, Zhang GF, Nguyen L.

PLoS Pathog. 2016 Oct 19;12(10):e1005949. doi: 10.1371/journal.ppat.1005949. eCollection 2016 Oct.

28.

Evaluation of a miniaturised single-stage thermal modulator for comprehensive two-dimensional gas chromatography of petroleum contaminated soils.

Jacobs MR, Edwards M, Górecki T, Nesterenko PN, Shellie RA.

J Chromatogr A. 2016 Sep 9;1463:162-8. doi: 10.1016/j.chroma.2016.08.009. Epub 2016 Aug 10.

PMID:
27527879
29.

Whole-Genome Comparative Analysis of Two Carbapenem-Resistant ST-258 Klebsiella pneumoniae Strains Isolated during a North-Eastern Ohio Outbreak: Differences within the High Heterogeneity Zones.

Ramirez MS, Xie G, Traglia GM, Johnson SL, Davenport KW, van Duin D, Ramazani A, Perez F, Jacobs MR, Sherratt DJ, Bonomo RA, Chain PS, Tolmasky ME.

Genome Biol Evol. 2016 Jul 3;8(6):2036-43. doi: 10.1093/gbe/evw135.

30.

The Changing Role of the Clinical Microbiology Laboratory in Defining Resistance in Gram-negatives.

Endimiani A, Jacobs MR.

Infect Dis Clin North Am. 2016 Jun;30(2):323-345. doi: 10.1016/j.idc.2016.02.002. Review.

PMID:
27208762
31.

Benefit-risk Evaluation for Diagnostics: A Framework (BED-FRAME).

Evans SR, Pennello G, Pantoja-Galicia N, Jiang H, Hujer AM, Hujer KM, Manca C, Hill C, Jacobs MR, Chen L, Patel R, Kreiswirth BN, Bonomo RA; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2016 Sep 15;63(6):812-7. doi: 10.1093/cid/ciw329. Epub 2016 May 18.

32.

Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Pneumococcal Carriage Among American Indians.

Grant LR, Hammitt LL, O'Brien SE, Jacobs MR, Donaldson C, Weatherholtz RC, Reid R, Santosham M, O'Brien KL.

Pediatr Infect Dis J. 2016 Aug;35(8):907-14. doi: 10.1097/INF.0000000000001207.

33.

Activity of nitazoxanide and tizoxanide against Mycobacterium tuberculosis in vitro and in whole blood culture.

Harausz EP, Chervenak KA, Good CE, Jacobs MR, Wallis RS, Sanchez-Felix M, Boom WH; TB Research Unit (TBRU) at Case Western Reserve University.

Tuberculosis (Edinb). 2016 May;98:92-6. doi: 10.1016/j.tube.2016.03.002. Epub 2016 Mar 22.

34.

Molecular Diversity and Plasmid Analysis of KPC-Producing Escherichia coli.

Chavda KD, Chen L, Jacobs MR, Bonomo RA, Kreiswirth BN.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4073-81. doi: 10.1128/AAC.00452-16. Print 2016 Jul.

35.

Hospitalizations and ED Visits in COPD: A Collision of Socioeconomic Realities with Chronic Comorbid Medical Illnesses.

Jacobs MR, Rastogi A, Criner GJ.

Chronic Obstr Pulm Dis. 2016 Apr 7;3(2):509-511. doi: 10.15326/jcopdf.3.2.2016.0139. No abstract available.

36.

Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment.

Wright MS, Iovleva A, Jacobs MR, Bonomo RA, Adams MD.

Genome Med. 2016 Mar 3;8(1):26. doi: 10.1186/s13073-016-0279-y.

37.

Could digital health applications improve the health of COPD patients?

Jacobs MR, Criner GJ.

Expert Rev Respir Med. 2016 Mar 10:1-2. [Epub ahead of print] No abstract available.

PMID:
26901449
38.

Environmental challenge: An effective approach for diagnosis and remediation of exacerbations of hypersensitivity pneumonitis.

Jacobs MR, Jacobs RL.

J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):537-8. doi: 10.1016/j.jaip.2015.12.004. Epub 2016 Feb 13. No abstract available.

PMID:
26883542
39.

PHOTO QUIZ: Immunosuppressed Patient Presenting With Fever, Interstitial Pneumonia, and Brain Lesions.

Stefaniuk CM, Stehura M, Sandhaus LM, Saade E, Fulton SA, Jacobs MR.

Clin Infect Dis. 2015 Dec 15;61(12):1839, 1888-9. doi: 10.1093/cid/civ702. No abstract available.

PMID:
26602031
40.

Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance.

Hong H, Xiao W, Lazarus HM, Good CE, Maitta RW, Jacobs MR.

Blood. 2016 Jan 28;127(4):496-502. doi: 10.1182/blood-2015-07-655944. Epub 2015 Nov 23.

41.

Back-flushing and heart cut capillary gas chromatography using planar microfluidic Deans' switching for the separation of benzene and alkylbenzenes in industrial samples.

Jacobs MR, Gras R, Nesterenko PN, Luong J, Shellie RA.

J Chromatogr A. 2015 Nov 20;1421:123-8. doi: 10.1016/j.chroma.2015.10.027. Epub 2015 Oct 22.

PMID:
26592465
42.

Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.

Viau R, Frank KM, Jacobs MR, Wilson B, Kaye K, Donskey CJ, Perez F, Endimiani A, Bonomo RA.

Clin Microbiol Rev. 2016 Jan;29(1):1-27. doi: 10.1128/CMR.00108-14. Review.

43.

Use of a SmartPhone/Tablet-Based Bidirectional Telemedicine Disease Management Program Facilitates Early Detection and Treatment of COPD Exacerbation Symptoms.

Smith HS, Criner AJ, Fehrle D, Grabianowski CL, Jacobs MR, Criner GJ.

Telemed J E Health. 2016 May;22(5):395-9. doi: 10.1089/tmj.2015.0135. Epub 2015 Oct 9.

44.

Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II.

Evans SR, Hujer AM, Jiang H, Hujer KM, Hall T, Marzan C, Jacobs MR, Sampath R, Ecker DJ, Manca C, Chavda K, Zhang P, Fernandez H, Chen L, Mediavilla JR, Hill CB, Perez F, Caliendo AM, Fowler VG Jr, Chambers HF, Kreiswirth BN, Bonomo RA; Antibacterial Resistance Leadership Group.

Clin Infect Dis. 2016 Jan 15;62(2):181-9. doi: 10.1093/cid/civ837. Epub 2015 Sep 25.

45.

The Safety of the Blood Supply--Time to Raise the Bar.

Jacobs MR, Lazarus HM, Maitta RW.

N Engl J Med. 2015 Aug 27;373(9):882. doi: 10.1056/NEJMc1507761. No abstract available.

PMID:
26308699
46.

A Telemedicine-Based Intervention Reduces the Frequency and Severity of COPD Exacerbation Symptoms: A Randomized, Controlled Trial.

Cordova FC, Ciccolella D, Grabianowski C, Gaughan J, Brennan K, Goldstein F, Jacobs MR, Criner GJ.

Telemed J E Health. 2016 Feb;22(2):114-122. doi: 10.1089/tmj.2015.0035. Epub 2015 Aug 10.

47.

Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae.

Khatri A, Naeger Murphy N, Wiest P, Osborn M, Garber K, Hecker M, Hurless K, Rudin SD, Jacobs MR, Kalayjian RC, Salata RA, van Duin D, Perez F, Bonomo RA, Paterson DL, Harris PN.

Antimicrob Agents Chemother. 2015 Aug;59(8):4375-8. doi: 10.1128/AAC.00553-15.

48.

Sulfamethoxazole susceptibility of Mycobacterium tuberculosis isolates from HIV-infected Ugandan adults with tuberculosis taking trimethoprim-sulfamethoxazole prophylaxis.

Ogwang S, Good CE, Okware B, Nsereko M, Jacobs MR, Boom WH, Bark CM.

Antimicrob Agents Chemother. 2015 Sep;59(9):5844-6. doi: 10.1128/AAC.01101-15. Epub 2015 Jul 13.

49.

Genome Sequence of a Klebsiella pneumoniae Sequence Type 258 Isolate with Prophage-Encoded K. pneumoniae Carbapenemase.

Chen L, Chavda KD, DeLeo FR, Bryant KA, Jacobs MR, Bonomo RA, Kreiswirth BN.

Genome Announc. 2015 Jun 18;3(3). pii: e00659-15. doi: 10.1128/genomeA.00659-15.

50.

Erratum for "New Insights into Dissemination and Variation of the Health Care-Associated Pathogen Acinetobacter baumannii from Genomic Analysis".

Wright MS, Haft DH, Harkins DM, Perez F, Hujer KM, Bajaksouzian S, Benard MF, Jacobs MR, Bonomo RA, Adams MD.

MBio. 2015 Jun 4;6(3):e00585. doi: 10.1128/mBio.00585-15. No abstract available.

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