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Items: 1 to 50 of 1342

1.

Gas Phase Electrodeposition Enabling the Programmable Three-Dimensional Growth of Multimodal Room Temperature Nano-Bridge Gas Sensor Array.

Isaac NA, Schlag L, Reiprich J, Katzer S, Nahrstedt H, Pezoldt J, Stauden T, Jacobs HO.

ACS Appl Mater Interfaces. 2019 Aug 19. doi: 10.1021/acsami.9b12545. [Epub ahead of print]

PMID:
31425645
2.

Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD.

Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA.

Neuroimage Clin. 2019 Aug 9;24:101978. doi: 10.1016/j.nicl.2019.101978. [Epub ahead of print]

3.

"In vivo imaging of the nucleus of the solitary tract with Magnetization Transfer at 7 Tesla".

Priovoulos N, Poser BA, Ivanov D, Verhey FR, Jacobs HI.

Neuroimage. 2019 Aug 6:116071. doi: 10.1016/j.neuroimage.2019.116071. [Epub ahead of print]

PMID:
31398435
4.

Optimal Detection of Subtle Gadolinium Leakage in CSF with Heavily T2-Weighted Fluid-Attenuated Inversion Recovery Imaging.

Freeze WM, Ter Weele DN, Palm WM, van Hooren RW, Hoff EI, Jansen JFA, Jacobs HIL, Verhey FR, Backes WH.

AJNR Am J Neuroradiol. 2019 Aug 8. doi: 10.3174/ajnr.A6145. [Epub ahead of print]

PMID:
31395665
5.

Fluidic Self-Assembly on Electroplated Multilayer Solder Bumps with Tailored Transformation Imprinted Melting Points.

Kaltwasser M, Schmidt U, Lösing L, Biswas S, Stauden T, Bund A, Jacobs HO.

Sci Rep. 2019 Aug 5;9(1):11325. doi: 10.1038/s41598-019-47690-8.

6.

Tropomyosin-related kinase A (TrkA) inhibition for the treatment of painful knee osteoarthritis: results from a randomized controlled phase 2a trial.

Watt F, Blauwet MB, Fakhoury A, Jacobs H, Smulders R, Lane NE.

Osteoarthritis Cartilage. 2019 Jul 26. pii: S1063-4584(19)31148-3. doi: 10.1016/j.joca.2019.05.029. [Epub ahead of print]

7.

GRAPH CONVOLUTIONAL NEURAL NETWORKS FOR ALZHEIMER'S DISEASE CLASSIFICATION.

Song TA, Roy Chowdhury S, Yang F, Jacobs H, El Fakhri G, Li Q, Johnson K, Dutta J.

Proc IEEE Int Symp Biomed Imaging. 2019 Apr;2019:414-417. doi: 10.1109/ISBI.2019.8759531. Epub 2019 Jul 11.

PMID:
31327984
8.

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.

Betts MJ, Kirilina E, Otaduy MCG, Ivanov D, Acosta-Cabronero J, Callaghan MF, Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu KY, Priovoulos N, Fliessbach K, Dahl MJ, Maaß A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner HR, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E, Hämmerer D.

Brain. 2019 Jul 20. pii: awz193. doi: 10.1093/brain/awz193. [Epub ahead of print]

PMID:
31327002
9.

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi-Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F.

EMBO J. 2019 Jul 15;38(14):e101564. doi: 10.15252/embj.2019101564. Epub 2019 Jun 17.

10.

Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model.

George J, Jacobs HT.

Biol Open. 2019 Jul 19;8(7). pii: bio042135. doi: 10.1242/bio.042135.

11.

[Utilization of individual out-of-pocket health services (IGeL) in persons with osteoarthritis in Germany : Results of a survey from the PROCLAIR study].

Jacobs H, Hoffmann F, Callhoff J, Postler A, Saam J, Zink A, Günther KP, Goronzy J.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Aug;62(8):1013-1019. doi: 10.1007/s00103-019-02986-y. German.

PMID:
31273415
12.

Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice.

Dhandapani PK, Lyyski AM, Paulin L, Khan NA, Suomalainen A, Auvinen P, Dufour E, Szibor M, Jacobs HT.

Physiol Rep. 2019 Aug;7(13):e14159. doi: 10.14814/phy2.14159.

13.

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.

Pilzecker B, Buoninfante OA, Jacobs H.

Nucleic Acids Res. 2019 Aug 22;47(14):7163-7181. doi: 10.1093/nar/gkz531.

PMID:
31251805
14.

Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults.

Biddle KD, d'Oleire Uquillas F, Jacobs HIL, Zide B, Kirn DR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.

Am J Geriatr Psychiatry. 2019 May 10. pii: S1064-7481(19)30360-4. doi: 10.1016/j.jagp.2019.05.005. [Epub ahead of print]

PMID:
31248770
15.

The Impact of a Group-Based Multidisciplinary Rehabilitation Program on the Quality of Life in Patients With Fibromyalgia: Results From the QUALIFIBRO Study.

Jacobs H, Bockaert M, Bonte J, DʼHaese M, Degrande J, Descamps L, Detaeye U, Goethals W, Janssens J, Matthys K, Muller L, Van de Walle H, Viane I, Vlieghe B, Grillet M, Asher R, Grillet B, De Bacquer D.

J Clin Rheumatol. 2019 Jun 19. doi: 10.1097/RHU.0000000000001120. [Epub ahead of print]

PMID:
31232906
16.

Alternative oxidase confers nutritional limitation on Drosophila development.

Saari S, Kemppainen E, Tuomela T, Oliveira MT, Dufour E, Jacobs HT.

J Exp Zool A Ecol Integr Physiol. 2019 Jul;331(6):341-356. doi: 10.1002/jez.2274. Epub 2019 Jun 20.

17.

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi-Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F.

EMBO J. 2019 Jun 17. pii: e101564. doi: 10.15252/embj.2019101564. [Epub ahead of print]

18.

Subthreshold amyloid and its biological and clinical meaning: Long way ahead.

Bischof GN, Jacobs HIL.

Neurology. 2019 Jul 9;93(2):72-79. doi: 10.1212/WNL.0000000000007747. Epub 2019 Jun 5. Review.

PMID:
31167933
19.

Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study.

Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedden T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson K.

JAMA Neurol. 2019 Jun 3. doi: 10.1001/jamaneurol.2019.1424. [Epub ahead of print]

20.

A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity.

Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J.

Inf Process Med Imaging. 2019;11492:384-393. doi: 10.1007/978-3-030-20351-1_29. Epub 2019 May 22.

PMID:
31156312
21.

Ultrasound-Guided Approaches to Improve Orthotopic Mouse Xenograft Models for Hepatocellular Carcinoma.

Bou About G, Thiebault E, Wattenhofer-Donzé M, Jacobs H, Guimond A, Sorg T, Robinet E, Baumert TF, Monassier L, Herault Y.

Curr Protoc Mouse Biol. 2019 Jun;9(2):e62. doi: 10.1002/cpmo.62. Epub 2019 May 30.

PMID:
31145554
22.

Alzheimer's disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms.

Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ.

Mol Psychiatry. 2019 May 28. doi: 10.1038/s41380-019-0437-x. [Epub ahead of print]

PMID:
31138892
23.

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma.

Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell SM, Feldman AL.

Blood. 2019 Jun 27;133(26):2776-2789. doi: 10.1182/blood.2019000626. Epub 2019 May 17.

PMID:
31101622
24.

Lethal Interaction of Nuclear and Mitochondrial Genotypes in Drosophila melanogaster.

Salminen TS, Cannino G, Oliveira MT, Lillsunde P, Jacobs HT, Kaguni LS.

G3 (Bethesda). 2019 Jul 9;9(7):2225-2234. doi: 10.1534/g3.119.400315.

25.

Premonitory Symptoms in Episodic and Chronic Migraine From a Pediatric Headache Clinic.

Jacobs H, Pakalnis A.

Pediatr Neurol. 2019 Aug;97:26-29. doi: 10.1016/j.pediatrneurol.2019.03.023. Epub 2019 Mar 29.

PMID:
31076200
26.

Water use indicators at farm scale - An agro-hydrological software solution.

Kraatz S, Libra JA, Drastig K, Hunstock U, Zare M, Jacobs H.

Sci Total Environ. 2019 Aug 15;678:133-145. doi: 10.1016/j.scitotenv.2019.04.368. Epub 2019 Apr 27.

PMID:
31075580
27.

Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid.

Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2019 Jun;78:178-185. doi: 10.1016/j.neurobiolaging.2019.02.019. Epub 2019 Mar 7.

PMID:
30947113
28.

Mutating for Good: DNA Damage Responses During Somatic Hypermutation.

Pilzecker B, Jacobs H.

Front Immunol. 2019 Mar 12;10:438. doi: 10.3389/fimmu.2019.00438. eCollection 2019. Review.

29.

Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred.

Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT.

J Prev Alzheimers Dis. 2019;6(2):112-120. doi: 10.14283/jpad.2019.6.

PMID:
30756118
30.

Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults.

Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, Price J, Chhatwal J, Rentz DM, Villemagne VL, Johnson KA, Sperling RA.

JAMA Neurol. 2019 May 1;76(5):542-551. doi: 10.1001/jamaneurol.2018.4693.

PMID:
30715078
31.

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress.

Villafañez F, García IA, Carbajosa S, Pansa MF, Mansilla S, Llorens MC, Angiolini V, Guantay L, Jacobs H, Madauss KP, Gloger I, Gottifredi V, Bocco JL, Soria G.

Oncogene. 2019 May;38(22):4310-4324. doi: 10.1038/s41388-019-0724-7. Epub 2019 Jan 31.

PMID:
30705406
32.

Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy.

Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ.

Stroke. 2019 Feb;50(2):328-335. doi: 10.1161/STROKEAHA.118.023788.

PMID:
30661497
33.

RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA.

González de Cózar JM, Gerards M, Teeri E, George J, Dufour E, Jacobs HT, Jõers P.

J Biol Chem. 2019 Mar 22;294(12):4331-4344. doi: 10.1074/jbc.RA118.007015. Epub 2019 Jan 11.

34.

Towards an understanding of C9orf82 protein/CAAP1 function.

Aslam MA, Alemdehy MF, Pritchard CEJ, Song JY, Muhaimin FI, Wijdeven RH, Huijbers IJ, Neefjes J, Jacobs H.

PLoS One. 2019 Jan 10;14(1):e0210526. doi: 10.1371/journal.pone.0210526. eCollection 2019.

35.

Resting-state fMRI in Parkinson's disease patients with cognitive impairment: A meta-analysis.

Wolters AF, van de Weijer SCF, Leentjens AFG, Duits AA, Jacobs HIL, Kuijf ML.

Parkinsonism Relat Disord. 2019 May;62:16-27. doi: 10.1016/j.parkreldis.2018.12.016. Epub 2018 Dec 17. Review.

PMID:
30580907
36.

STIM1 over-activation generates a multi-systemic phenotype affecting the skeletal muscle, spleen, eye, skin, bones and immune system in mice.

Silva-Rojas R, Treves S, Jacobs H, Kessler P, Messaddeq N, Laporte J, Böhm J.

Hum Mol Genet. 2019 May 15;28(10):1579-1593. doi: 10.1093/hmg/ddy446.

PMID:
30576443
37.

Regional tau pathology and loneliness in cognitively normal older adults.

d'Oleire Uquillas F, Jacobs HIL, Biddle KD, Properzi M, Hanseeuw B, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Donovan NJ.

Transl Psychiatry. 2018 Dec 18;8(1):282. doi: 10.1038/s41398-018-0345-x.

38.

The impact of amyloid-beta and tau on prospective cognitive decline in older individuals.

Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, Rabin JS, Jacobs H, Yang HS, Properzi M, Kirn DR, Rentz DM, Johnson KA.

Ann Neurol. 2019 Feb;85(2):181-193. doi: 10.1002/ana.25395. Epub 2019 Jan 21.

PMID:
30549303
39.

Where do white matter alterations dovetail with the cascade model of Alzheimer's disease?

Jacobs HIL, Buckley RF.

Brain. 2018 Oct 1;141(10):2830-2833. doi: 10.1093/brain/awy243. No abstract available.

PMID:
30535117
40.

Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy.

Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J.

EMBO Mol Med. 2019 Jan;11(1). pii: e9456. doi: 10.15252/emmm.201809456.

41.

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage.

Freeze WM, Jacobs HIL, Schreuder FHBM, van Oostenbrugge RJ, Backes WH, Verhey FR, Klijn CJM.

Front Neurol. 2018 Nov 12;9:926. doi: 10.3389/fneur.2018.00926. eCollection 2018.

42.

[Non-drug treatment of rheumatoid arthritis : An analysis of claims data and a survey of insured persons (Project PROCLAIR)].

Jacobs H, Callhoff J, Hoffmann F, Zink A, Albrecht K.

Z Rheumatol. 2019 Mar;78(2):119-126. doi: 10.1007/s00393-018-0567-6. German.

PMID:
30478638
43.

Core-Shell Transformation-Imprinted Solder Bumps Enabling Low-Temperature Fluidic Self-Assembly and Self-Alignment of Chips and High Melting Point Interconnects.

Kaltwasser M, Schmidt U, Biswas S, Reiprich J, Schlag L, Isaac NA, Stauden T, Jacobs HO.

ACS Appl Mater Interfaces. 2018 Nov 28;10(47):40608-40613. doi: 10.1021/acsami.8b12390. Epub 2018 Nov 15.

PMID:
30433752
44.

Neurogenetic contributions to amyloid beta and tau spreading in the human cortex.

Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA.

Nat Med. 2018 Dec;24(12):1910-1918. doi: 10.1038/s41591-018-0206-4. Epub 2018 Oct 29.

45.

Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells.

Du SW, Jacobs HM, Arkatkar T, Rawlings DJ, Jackson SW.

J Immunol. 2018 Dec 1;201(11):3258-3268. doi: 10.4049/jimmunol.1800393. Epub 2018 Oct 29.

PMID:
30373855
46.

Generation of functional murine CD11c+ age-associated B cells in the absence of B cell T-bet expression.

Du SW, Arkatkar T, Jacobs HM, Rawlings DJ, Jackson SW.

Eur J Immunol. 2019 Jan;49(1):170-178. doi: 10.1002/eji.201847641. Epub 2018 Nov 5.

PMID:
30353919
47.

Alternative respiratory chain enzymes: Therapeutic potential and possible pitfalls.

Saari S, Garcia GS, Bremer K, Chioda MM, Andjelković A, Debes PV, Nikinmaa M, Szibor M, Dufour E, Rustin P, Oliveira MT, Jacobs HT.

Biochim Biophys Acta Mol Basis Dis. 2019 Apr 1;1865(4):854-866. doi: 10.1016/j.bbadis.2018.10.012. Epub 2018 Oct 17.

48.

Alternative Oxidase Attenuates Cigarette Smoke-induced Lung Dysfunction and Tissue Damage.

Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M.

Am J Respir Cell Mol Biol. 2019 May;60(5):515-522. doi: 10.1165/rcmb.2018-0261OC.

49.

On the Extraction and Analysis of Graphs From Resting-State fMRI to Support a Correct and Robust Diagnostic Tool for Alzheimer's Disease.

Bachmann C, Jacobs HIL, Porta Mana P, Dillen K, Richter N, von Reutern B, Dronse J, Onur OA, Langen KJ, Fink GR, Kukolja J, Morrison A.

Front Neurosci. 2018 Sep 28;12:528. doi: 10.3389/fnins.2018.00528. eCollection 2018.

50.

Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes.

Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2018;66(2):811-823. doi: 10.3233/JAD-180676.

PMID:
30320590

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