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Items: 1 to 50 of 1285

1.

Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase.

Rodrigues APC, Camargo AF, Andjelković A, Jacobs HT, Oliveira MT.

Sci Rep. 2018 Jul 18;8(1):10882. doi: 10.1038/s41598-018-29150-x.

PMID:
30022066
2.

A schoolwide approach to promoting student bystander behavior in response to the use of the word "retard".

Siperstein GN, Albert AB, Jacobs HE, Osborne KJ, Stokes JE.

Res Dev Disabil. 2018 Jul 9;80:142-152. doi: 10.1016/j.ridd.2018.06.016. [Epub ahead of print]

PMID:
30015272
3.

Chronotype differences in cortical thickness: grey matter reflects when you go to bed.

Rosenberg J, Jacobs HIL, Maximov II, Reske M, Shah NJ.

Brain Struct Funct. 2018 Jun 15. doi: 10.1007/s00429-018-1697-y. [Epub ahead of print]

PMID:
29948193
4.

Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline.

Bos I, Verhey FR, Ramakers IHGB, Jacobs HIL, Soininen H, Freund-Levi Y, Hampel H, Tsolaki M, Wallin ÅK, van Buchem MA, Oleksik A, Verbeek MM, Rikkert MO, van der Flier WM, Scheltens P, Aalten P, Visser PJ, Vos SJB.

Alzheimers Res Ther. 2018 Jun 20;10(1):56. doi: 10.1186/s13195-018-0391-x.

5.

Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study.

Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A.

Neurobiol Aging. 2018 May 24;69:167-176. doi: 10.1016/j.neurobiolaging.2018.05.021. [Epub ahead of print]

PMID:
29908415
6.

TACI deletion protects against progressive murine lupus nephritis induced by BAFF overexpression.

Arkatkar T, Jacobs HM, Du SW, Li QZ, Hudkins KL, Alpers CE, Rawlings DJ, Jackson SW.

Kidney Int. 2018 Jun 12. pii: S0085-2538(18)30252-7. doi: 10.1016/j.kint.2018.03.012. [Epub ahead of print]

PMID:
29907458
7.

Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts.

Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, Maruff P, Donohue MC, Rentz DM, Kirn D, Hedden T, Chhatwal J, Schultz AP, Johnson KA, Villemagne VL, Sperling RA; Alzheimer's Disease Neuroimaging Initiative; Australian Imaging, Biomarker and Lifestyle study of ageing; Harvard Aging Brain Study.

Alzheimers Dement. 2018 May 24. pii: S1552-5260(18)30132-8. doi: 10.1016/j.jalz.2018.04.010. [Epub ahead of print]

PMID:
29803541
8.

Severe combined immunodeficiency in Sting V154M/WT mice.

Bouis D, Kirstetter P, Arbogast F, Lamon D, Delgado V, Jung S, Ebel C, Jacobs H, Knapp AM, Jeremiah N, Belot A, Martin T, Crow YJ, André-Schmutz I, Korganow AS, Rieux-Laucat F, Soulas-Sprauel P.

J Allergy Clin Immunol. 2018 May 23. pii: S0091-6749(18)30758-9. doi: 10.1016/j.jaci.2018.04.034. [Epub ahead of print]

PMID:
29800647
9.

PET staging of amyloidosis using striatum.

Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA; Alzheimer's Disease Neuroimaging Initiative; Harvard Aging Brain Study.

Alzheimers Dement. 2018 May 21. pii: S1552-5260(18)30133-X. doi: 10.1016/j.jalz.2018.04.011. [Epub ahead of print]

10.

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system.

Buoninfante OA, Pilzecker B, Aslam MA, Zavrakidis I, van der Wiel R, van de Ven M, van den Berk PCM, Jacobs H.

Oncotarget. 2018 Apr 10;9(27):18832-18843. doi: 10.18632/oncotarget.24777. eCollection 2018 Apr 10.

11.

Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia.

Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL.

Neurobiol Aging. 2018 Aug;68:48-58. doi: 10.1016/j.neurobiolaging.2018.03.029. Epub 2018 Apr 5.

12.

18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal.

Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA.

J Alzheimers Dis. 2018;62(4):1691-1702. doi: 10.3233/JAD-170840.

13.

Nrf2a modulates the embryonic antioxidant response to perfluorooctanesulfonic acid (PFOS) in the zebrafish, Danio rerio.

Sant KE, Sinno PP, Jacobs HM, Timme-Laragy AR.

Aquat Toxicol. 2018 May;198:92-102. doi: 10.1016/j.aquatox.2018.02.010. Epub 2018 Feb 20.

PMID:
29524743
14.

Polyadenylation and degradation of structurally abnormal mitochondrial tRNAs in human cells.

Toompuu M, Tuomela T, Laine P, Paulin L, Dufour E, Jacobs HT.

Nucleic Acids Res. 2018 Jun 1;46(10):5209-5226. doi: 10.1093/nar/gky159.

15.

Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase.

Ciesielski GL, Nadalutti CA, Oliveira MT, Jacobs HT, Griffith JD, Kaguni LS.

Nucleic Acids Res. 2018 Apr 6;46(6):3034-3046. doi: 10.1093/nar/gky094.

16.

Incidence Rates of and Mortality after Hip Fracture among German Nursing Home Residents.

Jacobs H, Zeeb H, Hoffmann F.

Int J Environ Res Public Health. 2018 Feb 7;15(2). pii: E289. doi: 10.3390/ijerph15020289.

17.

Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals.

Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA.

Nat Neurosci. 2018 Mar;21(3):424-431. doi: 10.1038/s41593-018-0070-z. Epub 2018 Feb 5.

PMID:
29403032
18.

Xenotopic expression of alternative electron transport enzymes in animal mitochondria and their impact in health and disease.

Camargo AF, Chioda MM, Rodrigues APC, Garcia GS, McKinney EA, Jacobs HT, Oliveira MT.

Cell Biol Int. 2018 Jun;42(6):664-669. doi: 10.1002/cbin.10943. Epub 2018 Feb 23. Review.

PMID:
29384231
19.

Mitochondria are physiologically maintained at close to 50 °C.

Chrétien D, Bénit P, Ha HH, Keipert S, El-Khoury R, Chang YT, Jastroch M, Jacobs HT, Rustin P, Rak M.

PLoS Biol. 2018 Jan 25;16(1):e2003992. doi: 10.1371/journal.pbio.2003992. eCollection 2018 Jan.

20.

Arabinoxylo-Oligosaccharides and Inulin Impact Inter-Individual Variation on Microbial Metabolism and Composition, Which Immunomodulates Human Cells.

Van den Abbeele P, Taminiau B, Pinheiro I, Duysburgh C, Jacobs H, Pijls L, Marzorati M.

J Agric Food Chem. 2018 Feb 7;66(5):1121-1130. doi: 10.1021/acs.jafc.7b04611. Epub 2018 Jan 24.

PMID:
29363966
21.

Intracellular vesicle trafficking plays an essential role in mitochondrial quality control.

Gerards M, Cannino G, de Cózar JMG, Jacobs HT.

Mol Biol Cell. 2018 Jan 17. pii: mbc.E17-10-0619. doi: 10.1091/mbc.E17-10-0619. [Epub ahead of print]

22.

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline.

Bos I, Verhey FR, Ramakers IHGB, Jacobs HIL, Soininen H, Freund-Levi Y, Hampel H, Tsolaki M, Wallin ÅK, van Buchem MA, Oleksik A, Verbeek MM, Olde Rikkert M, van der Flier WM, Scheltens P, Aalten P, Visser PJ, Vos SJB.

Alzheimers Res Ther. 2017 Dec 29;9(1):101. doi: 10.1186/s13195-017-0328-9. Erratum in: Alzheimers Res Ther. 2018 Jun 20;10(1):56.

23.

Embryonic exposure to Mono(2-ethylhexyl) phthalate (MEHP) disrupts pancreatic organogenesis in zebrafish (Danio rerio).

Jacobs HM, Sant KE, Basnet A, Williams LM, Moss JB, Timme-Laragy AR.

Chemosphere. 2018 Mar;195:498-507. doi: 10.1016/j.chemosphere.2017.12.094. Epub 2017 Dec 15.

PMID:
29277029
24.

Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals.

d'Oleire Uquillas F, Jacobs HIL, Hanseeuw B, Marshall GA, Properzi M, Schultz AP, LaPoint MR, Johnson KA, Sperling RA, Vannini P.

Neuroimage Clin. 2017 Oct 31;17:388-396. doi: 10.1016/j.nicl.2017.10.034. eCollection 2018.

25.

CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness.

Ahrends T, Spanjaard A, Pilzecker B, Bąbała N, Bovens A, Xiao Y, Jacobs H, Borst J.

Immunity. 2017 Nov 21;47(5):848-861.e5. doi: 10.1016/j.immuni.2017.10.009. Epub 2017 Nov 7.

PMID:
29126798
26.

Non-invasive quantitative imaging of hepatocellular carcinoma growth in mice by micro-CT using liver-targeted iodinated nano-emulsions.

Anton N, Parlog A, Bou About G, Attia MF, Wattenhofer-Donzé M, Jacobs H, Goncalves I, Robinet E, Sorg T, Vandamme TF.

Sci Rep. 2017 Oct 24;7(1):13935. doi: 10.1038/s41598-017-14270-7.

27.

The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline.

Jacobs HIL, Hopkins DA, Mayrhofer HC, Bruner E, van Leeuwen FW, Raaijmakers W, Schmahmann JD.

Brain. 2018 Jan 1;141(1):37-47. doi: 10.1093/brain/awx194.

PMID:
29053771
28.

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.

Arkatkar T, Du SW, Jacobs HM, Dam EM, Hou B, Buckner JH, Rawlings DJ, Jackson SW.

J Exp Med. 2017 Nov 6;214(11):3207-3217. doi: 10.1084/jem.20170580. Epub 2017 Sep 12.

29.

Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity.

Vujanovic M, Krietsch J, Raso MC, Terraneo N, Zellweger R, Schmid JA, Taglialatela A, Huang JW, Holland CL, Zwicky K, Herrador R, Jacobs H, Cortez D, Ciccia A, Penengo L, Lopes M.

Mol Cell. 2017 Sep 7;67(5):882-890.e5. doi: 10.1016/j.molcel.2017.08.010.

30.

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.

Wendling O, Champy MF, Jaubert S, Pavlovic G, Dubos A, Lindner L, Jacobs H, Mark M, Combe R, Da Cruz IG, Luche H, Mudgett JS, Rosahl T, Sorg T, Malissen M, Reilly PT, Hérault Y.

Sci Rep. 2017 Aug 29;7(1):9618. doi: 10.1038/s41598-017-08845-7.

31.

DNA damage tolerance in hematopoietic stem and progenitor cells in mice.

Pilzecker B, Buoninfante OA, van den Berk P, Lancini C, Song JY, Citterio E, Jacobs H.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6875-E6883. doi: 10.1073/pnas.1706508114. Epub 2017 Jul 31.

32.

High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T.

Priovoulos N, Jacobs HIL, Ivanov D, Uludağ K, Verhey FRJ, Poser BA.

Neuroimage. 2018 Mar;168:427-436. doi: 10.1016/j.neuroimage.2017.07.045. Epub 2017 Jul 22.

PMID:
28743460
33.

Multipole Vortex Blobs (MVB): Symplectic Geometry and Dynamics.

Holm DD, Jacobs HO.

J Nonlinear Sci. 2017;27(3):973-1006. doi: 10.1007/s00332-017-9367-4. Epub 2017 Mar 16.

34.

Pericortical Enhancement on Delayed Postgadolinium Fluid-Attenuated Inversion Recovery Images in Normal Aging, Mild Cognitive Impairment, and Alzheimer Disease.

Freeze WM, Schnerr RS, Palm WM, Jansen JF, Jacobs HI, Hoff EI, Verhey FR, Backes WH.

AJNR Am J Neuroradiol. 2017 Sep;38(9):1742-1747. doi: 10.3174/ajnr.A5273. Epub 2017 Jul 6.

PMID:
28684457
35.

Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogaster.

Saari S, Andjelković A, Garcia GS, Jacobs HT, Oliveira MT.

BMC Dev Biol. 2017 Jul 3;17(1):9. doi: 10.1186/s12861-017-0151-3.

36.

Functional Disintegration of the Default Mode Network in Prodromal Alzheimer's Disease.

Dillen KNH, Jacobs HIL, Kukolja J, Richter N, von Reutern B, Onur ÖA, Langen KJ, Fink GR.

J Alzheimers Dis. 2017;59(1):169-187. doi: 10.3233/JAD-161120.

PMID:
28598839
37.

Neuroimaging markers associated with maintenance of optimal memory performance in late-life.

Dekhtyar M, Papp KV, Buckley R, Jacobs HIL, Schultz AP, Johnson KA, Sperling RA, Rentz DM.

Neuropsychologia. 2017 Jun;100:164-170. doi: 10.1016/j.neuropsychologia.2017.04.037. Epub 2017 May 1.

38.

The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study.

Cleutjens FAHM, Ponds RWHM, Spruit MA, Burgmans S, Jacobs HIL, Gronenschild EHBM, Staals J, Franssen FME, Dijkstra JB, Vanfleteren LEGW, Hofman PA, Wouters EFM, Janssen DJA.

Front Aging Neurosci. 2017 Mar 30;9:88. doi: 10.3389/fnagi.2017.00088. eCollection 2017.

39.

Progressive Fatal Neurological Decline in an Adolescent.

Jacobs HS, Roach ES.

Pediatr Neurol. 2017 Jun;71:84-85. doi: 10.1016/j.pediatrneurol.2017.03.007. Epub 2017 Mar 22. No abstract available.

PMID:
28408151
40.

Assessment of Toxicological Perturbations and Variants of Pancreatic Islet Development in the Zebrafish Model.

Sant KE, Jacobs HM, Xu J, Borofski KA, Moss LG, Moss JB, Timme-Laragy AR.

Toxics. 2016 Sep;4(3). pii: 20. doi: 10.3390/toxics4030020. Epub 2016 Sep 2.

41.

Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells.

Hale M, Lee B, Honaker Y, Leung WH, Grier AE, Jacobs HM, Sommer K, Sahni J, Jackson SW, Scharenberg AM, Astrakhan A, Rawlings DJ.

Mol Ther Methods Clin Dev. 2017 Jan 10;4:192-203. doi: 10.1016/j.omtm.2016.12.008. eCollection 2017 Mar 17.

42.

Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila.

Salminen TS, Oliveira MT, Cannino G, Lillsunde P, Jacobs HT, Kaguni LS.

Mitochondrion. 2017 May;34:75-83. doi: 10.1016/j.mito.2017.02.001. Epub 2017 Feb 16.

PMID:
28214560
43.

Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction.

Badal SAM, Asuncion Valenzuela MM, Zylstra D, Huang G, Vendantam P, Francis S, Quitugua A, Amis LH, Davis W, Tzeng TJ, Jacobs H, Gangemi DJ, Raner G, Rowland L, Wooten J, Campbell P, Brantley E, Delgoda R.

J Appl Toxicol. 2017 Jul;37(7):873-883. doi: 10.1002/jat.3436. Epub 2017 Jan 31.

44.

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.

Szibor M, Dhandapani PK, Dufour E, Holmström KM, Zhuang Y, Salwig I, Wittig I, Heidler J, Gizatullina Z, Gainutdinov T; German Mouse Clinic Consortium, Fuchs H, Gailus-Durner V, de Angelis MH, Nandania J, Velagapudi V, Wietelmann A, Rustin P, Gellerich FN, Jacobs HT, Braun T.

Dis Model Mech. 2017 Feb 1;10(2):163-171. doi: 10.1242/dmm.027839. Epub 2016 Dec 14.

45.

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Sellier C, Buijsen RAM, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, Oulad-Abdelghani M, Eberling P, Ruffenach F, Joint M, Anheim M, Martinez-Cerdeno V, Tassone F, Willemsen R, Hukema RK, Viville S, Martinat C, Todd PK, Charlet-Berguerand N.

Neuron. 2017 Jan 18;93(2):331-347. doi: 10.1016/j.neuron.2016.12.016. Epub 2017 Jan 5.

46.

Capsaicin 8% patch repeat treatment plus standard of care (SOC) versus SOC alone in painful diabetic peripheral neuropathy: a randomised, 52-week, open-label, safety study.

Vinik AI, Perrot S, Vinik EJ, Pazdera L, Jacobs H, Stoker M, Long SK, Snijder RJ, van der Stoep M, Ortega E, Katz N.

BMC Neurol. 2016 Dec 6;16(1):251.

47.

Sticks, Stones, and Stigma: Student Bystander Behavior in Response to Hearing the Word "Retard".

Albert AB, Jacobs HE, Siperstein GN.

Intellect Dev Disabil. 2016 Dec;54(6):391-401.

PMID:
27893318
48.

Erratum to: Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development.

Jacobs HN, Rathod S, Wolf MT, Elisseeff JH.

AAPS J. 2017 Mar;19(2):595. doi: 10.1208/s12248-016-0012-1. No abstract available.

PMID:
27844404
49.

Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation.

Jackson SW, Scharping NE, Jacobs HM, Wang S, Chait A, Rawlings DJ.

J Immunol. 2016 Dec 15;197(12):4529-4534. Epub 2016 Nov 11.

50.

Embryonic exposures to perfluorooctanesulfonic acid (PFOS) disrupt pancreatic organogenesis in the zebrafish, Danio rerio.

Sant KE, Jacobs HM, Borofski KA, Moss JB, Timme-Laragy AR.

Environ Pollut. 2017 Jan;220(Pt B):807-817. doi: 10.1016/j.envpol.2016.10.057. Epub 2016 Oct 31.

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