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Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype.

Hesse R, Hurtado ML, Jackson RJ, Eaton SL, Herrmann AG, Colom-Cadena M, Tzioras M, King D, Rose J, Tulloch J, McKenzie CA, Smith C, Henstridge CM, Lamont D, Wishart TM, Spires-Jones TL.

Acta Neuropathol Commun. 2019 Dec 20;7(1):214. doi: 10.1186/s40478-019-0847-7.


Clusterin accumulates in synapses in Alzheimer's disease and is increased in apolipoprotein E4 carriers.

Jackson RJ, Rose J, Tulloch J, Henstridge C, Smith C, Spires-Jones TL.

Brain Commun. 2019;1(1):fcz003. doi: 10.1093/braincomms/fcz003. Epub 2019 Jun 24.


Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.

Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL.

Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044.


A hierarchical role of IL-25 in ILC development and function at the lung mucosae following viral-vector vaccination.

Li Z, Jackson RJ, Ranasinghe C.

Vaccine X. 2019 Jul 16;2:100035. doi: 10.1016/j.jvacx.2019.100035. eCollection 2019 Aug 9.


Mucosal and systemic SIV-specific cytotoxic CD4+ T cell hierarchy in protection following intranasal/intramuscular recombinant pox-viral vaccination of pigtail macaques.

Khanna M, Jackson RJ, Alcantara S, Amarasena TH, Li Z, Kelleher AD, Kent SJ, Ranasinghe C.

Sci Rep. 2019 Apr 5;9(1):5661. doi: 10.1038/s41598-019-41506-5.


Viral vector and route of administration determine the ILC and DC profiles responsible for downstream vaccine-specific immune outcomes.

Roy S, Jaeson MI, Li Z, Mahboob S, Jackson RJ, Grubor-Bauk B, Wijesundara DK, Gowans EJ, Ranasinghe C.

Vaccine. 2019 Feb 28;37(10):1266-1276. doi: 10.1016/j.vaccine.2019.01.045. Epub 2019 Feb 4.


Chemically Treated 3D Printed Polymer Scaffolds for Biomineral Formation.

Jackson RJ, Patrick PS, Page K, Powell MJ, Lythgoe MF, Miodownik MA, Parkin IP, Carmalt CJ, Kalber TL, Bear JC.

ACS Omega. 2018 Apr 30;3(4):4342-4351. doi: 10.1021/acsomega.8b00219. Epub 2018 Apr 19.


Unexpected involvement of IL-13 signalling via a STAT6 independent mechanism during murine IgG2a development following viral vaccination.

Hamid MA, Jackson RJ, Roy S, Khanna M, Ranasinghe C.

Eur J Immunol. 2018 Jul;48(7):1153-1163. doi: 10.1002/eji.201747463. Epub 2018 May 10.


Vaccination route can significantly alter the innate lymphoid cell subsets: a feedback between IL-13 and IFN-γ.

Li Z, Jackson RJ, Ranasinghe C.

NPJ Vaccines. 2018 Mar 12;3:10. doi: 10.1038/s41541-018-0048-6. eCollection 2018.


sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling.

Hesse R, von Einem B, Wagner F, Bott P, Schwanzar D, Jackson RJ, Föhr KJ, Lausser L, Kroker KS, Proepper C, Walther P, Kestler HA, Spires-Jones TL, Boeckers T, Rosenbrock H, von Arnim CAF.

Exp Neurol. 2018 Jun;304:1-13. doi: 10.1016/j.expneurol.2018.02.010. Epub 2018 Feb 18.


Long-term Evaluation of Cervical Disc Arthroplasty with the Mobi-C© Cervical Disc: A Randomized, Prospective, Multicenter Clinical Trial with Seven-Year Follow-up.

Radcliff K, Davis RJ, Hisey MS, Nunley PD, Hoffman GA, Jackson RJ, Bae HW, Albert T, Coric D.

Int J Spine Surg. 2017 Nov 28;11:31. doi: 10.14444/4031. eCollection 2017.


Sternocostal slipping rib syndrome.

Bonasso PC, Petrus SN, Smith SD, Jackson RJ.

Pediatr Surg Int. 2018 Mar;34(3):331-333. doi: 10.1007/s00383-017-4221-1. Epub 2017 Dec 6.


Conditional Deletion of PDK1 in the Forebrain Causes Neuron Loss and Increased Apoptosis during Cortical Development.

Xu C, Yu L, Hou J, Jackson RJ, Wang H, Huang C, Liu T, Wang Q, Zou X, Morris RG, Spires-Jones TL, Yang Z, Yin Z, Xu Y, Chen G.

Front Cell Neurosci. 2017 Oct 20;11:330. doi: 10.3389/fncel.2017.00330. eCollection 2017.


Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.

Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse TL, Spires-Jones TL, Walsh DM.

J Neurosci. 2017 Dec 6;37(49):11947-11966. doi: 10.1523/JNEUROSCI.2009-17.2017. Epub 2017 Nov 3.


Nd:YAG laser therapy for rectal and vaginal venous malformations.

Gurien LA, Jackson RJ, Kiser MM, Richter GT.

Pediatr Surg Int. 2017 Aug;33(8):887-891. doi: 10.1007/s00383-017-4113-4. Epub 2017 Jun 14.


Tau association with synaptic vesicles causes presynaptic dysfunction.

Zhou L, McInnes J, Wierda K, Holt M, Herrmann AG, Jackson RJ, Wang YC, Swerts J, Beyens J, Miskiewicz K, Vilain S, Dewachter I, Moechars D, De Strooper B, Spires-Jones TL, De Wit J, Verstreken P.

Nat Commun. 2017 May 11;8:15295. doi: 10.1038/ncomms15295.


The ROI-C zero-profile anchored spacer for anterior cervical discectomy and fusion: biomechanical profile and clinical outcomes.

Bucci MN, Oh D, Cowan RS, Davis RJ, Jackson RJ, Tyndall DS, Nehls D.

Med Devices (Auckl). 2017 Apr 18;10:61-69. doi: 10.2147/MDER.S127133. eCollection 2017.


Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK.

Ritchie DL, Adlard P, Peden AH, Lowrie S, Le Grice M, Burns K, Jackson RJ, Yull H, Keogh MJ, Wei W, Chinnery PF, Head MW, Ironside JW.

Acta Neuropathol. 2017 Aug;134(2):221-240. doi: 10.1007/s00401-017-1703-0. Epub 2017 Mar 27.


VICTOR: Vinflunine in advanced metastatic transitional cell carcinoma of the urothelium: A retrospective analysis of the use of vinflunine in multi-centre real life setting as second line chemotherapy through Free of Charge Programme for patients in the UK and Ireland.

Hussain SA, Ansari J, Huddart R, Power DG, Lyons J, Wylie J, Vilarino-Varlela M, Elander NO, McMenemin R, Pickering LM, Faust G, Chauhan S, Jackson RJ.

Int J Oncol. 2017 Mar;50(3):768-772. doi: 10.3892/ijo.2017.3847. Epub 2017 Jan 13.


Recombinant fowlpox virus vector-based vaccines: expression kinetics, dissemination and safety profile following intranasal delivery.

Townsend DG, Trivedi S, Jackson RJ, Ranasinghe C.

J Gen Virol. 2017 Mar;98(3):496-505. doi: 10.1099/jgv.0.000702. Epub 2017 Apr 1.


Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.

Jackson RJ, Rudinskiy N, Herrmann AG, Croft S, Kim JM, Petrova V, Ramos-Rodriguez JJ, Pitstick R, Wegmann S, Garcia-Alloza M, Carlson GA, Hyman BT, Spires-Jones TL.

Eur J Neurosci. 2016 Dec;44(12):3056-3066. doi: 10.1111/ejn.13442. Epub 2016 Nov 12.


Subsequent surgery rates after cervical total disc replacement using a Mobi-C Cervical Disc Prosthesis versus anterior cervical discectomy and fusion: a prospective randomized clinical trial with 5-year follow-up.

Jackson RJ, Davis RJ, Hoffman GA, Bae HW, Hisey MS, Kim KD, Gaede SE, Nunley PD.

J Neurosurg Spine. 2016 May;24(5):734-45. doi: 10.3171/2015.8.SPINE15219. Epub 2016 Jan 22.


Erratum to: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.

Henstridge CM, Jackson RJ, Kim JM, Herrmann AG, Wright AK, Harris SE, Bastin ME, Starr JM, Wardlaw J, Gillingwater TH, Smith C, McKenzie CA, Cox SR, Deary IJ, Spires-Jones TL.

Acta Neuropathol Commun. 2015 Dec 9;3(1):83. doi: 10.1186/s40478-015-0244-9.


"Independence" Day.

Lemery J, Jackson RJ.

Ann Glob Health. 2015 May-Jun;81(3):416-7. doi: 10.1016/j.aogh.2015.06.005. No abstract available.


Letter to the Editor: Response to letters regarding Mobi-C cervical artificial disc.

Nunley PD, Stone MB, Hisey MS, Kim KD, Jackson RJ, Bae HW, Hoffman GA, Gaede SE, Danielson GO 3rd, Gordon C, Davis RJ, Rami B.

J Neurosurg Spine. 2016 Mar;24(3):516-8. doi: 10.3171/2015.6.SPINE15707. Epub 2015 Nov 13. No abstract available.


Identification of biomarkers to measure HIV-specific mucosal and systemic CD8(+) T-cell immunity using single cell Fluidigm 48.48 Dynamic arrays.

Trivedi S, Neeman T, Jackson RJ, Ranasinghe R, Jack C, Ranasinghe C.

Vaccine. 2015 Dec 16;33(51):7315-7327. doi: 10.1016/j.vaccine.2015.10.085. Epub 2015 Nov 11.


Stand-alone interspinous spacer versus decompressive laminectomy for treatment of lumbar spinal stenosis.

Lauryssen C, Jackson RJ, Baron JM, Tallarico RA, Lavelle WF, Deutsch H, Block JE, Geisler FH.

Expert Rev Med Devices. 2015;12(6):763-9. doi: 10.1586/17434440.2015.1100071. Epub 2015 Oct 21.


Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.

Henstridge CM, Jackson RJ, Kim JM, Herrmann AG, Wright AK, Harris SE, Bastin ME, Starr JM, Wardlaw J, Gillingwater TH, Smith C, McKenzie CA, Cox SR, Deary IJ, Spires-Jones TL.

Acta Neuropathol Commun. 2015 Sep 4;3:53. doi: 10.1186/s40478-015-0232-0. Erratum in: Acta Neuropathol Commun. 2015;3(1):83.


Extensive Fetal Congenital Subcutaneous Mixed Venous Lymphatic Lesion: Prenatal Diagnosis and Postnatal Management.

Odibo IN, Linam LE, Richter GE, Jackson RJ, Dajani NK.

AJP Rep. 2015 Apr;5(1):e37-42. doi: 10.1055/s-0034-1544107. Epub 2015 Feb 25.


An internal thioester in a pathogen surface protein mediates covalent host binding.

Walden M, Edwards JM, Dziewulska AM, Bergmann R, Saalbach G, Kan SY, Miller OK, Weckener M, Jackson RJ, Shirran SL, Botting CH, Florence GJ, Rohde M, Banfield MJ, Schwarz-Linek U.

Elife. 2015 Jun 2;4. doi: 10.7554/eLife.06638.


Comparison of Clinical Outcomes of 1- and 2-Level Total Disc Replacement: Four-Year Results From a Prospective, Randomized, Controlled, Multicenter IDE Clinical Trial.

Bae HW, Kim KD, Nunley PD, Jackson RJ, Hisey MS, Davis RJ, Hoffman GA, Gaede SE, Danielson GO 3rd, Peterson DL, Stokes JM, Araghi A.

Spine (Phila Pa 1976). 2015 Jun 1;40(11):759-66. doi: 10.1097/BRS.0000000000000887.


Public awareness of and support for infrastructure changes designed to increase walking and biking in Los Angeles County.

Gase LN, Barragan NC, Simon PA, Jackson RJ, Kuo T.

Prev Med. 2015 Mar;72:70-5. doi: 10.1016/j.ypmed.2014.12.033. Epub 2015 Jan 5.


IL-17A expression in HIV-specific CD8 T cells is regulated by IL-4/IL-13 following HIV-1 prime-boost immunization.

Ravichandran J, Jackson RJ, Trivedi S, Ranasinghe C.

J Interferon Cytokine Res. 2015 Mar;35(3):176-85. doi: 10.1089/jir.2014.0078. Epub 2014 Dec 10.


Two-level total disc replacement with Mobi-C cervical artificial disc versus anterior discectomy and fusion: a prospective, randomized, controlled multicenter clinical trial with 4-year follow-up results.

Davis RJ, Nunley PD, Kim KD, Hisey MS, Jackson RJ, Bae HW, Hoffman GA, Gaede SE, Danielson GO 3rd, Gordon C, Stone MB.

J Neurosurg Spine. 2015 Jan;22(1):15-25. doi: 10.3171/2014.7.SPINE13953.


Different HIV pox viral vector-based vaccines and adjuvants can induce unique antigen presenting cells that modulate CD8 T cell avidity.

Trivedi S, Jackson RJ, Ranasinghe C.

Virology. 2014 Nov;468-470:479-489. doi: 10.1016/j.virol.2014.09.004. Epub 2014 Sep 28.


Use of an in vivo FTA assay to assess the magnitude, functional avidity and epitope variant cross-reactivity of T cell responses following HIV-1 recombinant poxvirus vaccination.

Wijesundara DK, Ranasinghe C, Jackson RJ, Lidbury BA, Parish CR, Quah BJ.

PLoS One. 2014 Aug 29;9(8):e105366. doi: 10.1371/journal.pone.0105366. eCollection 2014.


IL-4 and IL-13 receptors: Roles in immunity and powerful vaccine adjuvants.

Ranasinghe C, Trivedi S, Wijesundara DK, Jackson RJ.

Cytokine Growth Factor Rev. 2014 Aug;25(4):437-42. doi: 10.1016/j.cytogfr.2014.07.010. Epub 2014 Jul 23. Review.


Novel HIV IL-4R antagonist vaccine strategy can induce both high avidity CD8 T and B cell immunity with greater protective efficacy.

Jackson RJ, Worley M, Trivedi S, Ranasinghe C.

Vaccine. 2014 Sep 29;32(43):5703-14. doi: 10.1016/j.vaccine.2014.08.023. Epub 2014 Aug 20.


The organization of RNA contacts by PTB for regulation of FAS splicing.

Mickleburgh I, Kafasla P, Cherny D, Llorian M, Curry S, Jackson RJ, Smith CW.

Nucleic Acids Res. 2014 Jul;42(13):8605-20. doi: 10.1093/nar/gku519. Epub 2014 Jun 23.


Progresses in DNA-based heterologous prime-boost immunization strategies.

Jackson RJ, Boyle DB, Ranasinghe C.

Methods Mol Biol. 2014;1143:61-90. doi: 10.1007/978-1-4939-0410-5_5.


Persistent gastrocutaneous fistula: factors affecting the need for closure.

Wyrick DL, Bozeman AP, Smith SD, Jackson RJ, Maxson RT, Kelley KR, Mathews DL, Li J, Swearingen CJ, Dassinger MS.

J Pediatr Surg. 2013 Dec;48(12):2506-10. doi: 10.1016/j.jpedsurg.2013.06.001.


Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1.

Gilder AS, Chen YB, Jackson RJ 3rd, Jiang J, Maher JF.

Biochem Biophys Res Commun. 2013 Oct 25;440(3):431-6. doi: 10.1016/j.bbrc.2013.09.090. Epub 2013 Sep 25.


IL-4 and IL-13 mediated down-regulation of CD8 expression levels can dampen anti-viral CD8⁺ T cell avidity following HIV-1 recombinant pox viral vaccination.

Wijesundara DK, Jackson RJ, Tscharke DC, Ranasinghe C.

Vaccine. 2013 Sep 23;31(41):4548-55. doi: 10.1016/j.vaccine.2013.07.062. Epub 2013 Aug 6.


Health and the built environment: 10 years after.

Jackson RJ, Dannenberg AL, Frumkin H.

Am J Public Health. 2013 Sep;103(9):1542-4. doi: 10.2105/AJPH.2013.301482. Epub 2013 Jul 18. No abstract available.


Unique IL-13Rα2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8(+) T-cell avidity and protective immunity.

Ranasinghe C, Trivedi S, Stambas J, Jackson RJ.

Mucosal Immunol. 2013 Nov;6(6):1068-80. doi: 10.1038/mi.2013.1. Epub 2013 Feb 13.


Reduced interleukin-4 receptor α expression on CD8+ T cells correlates with higher quality anti-viral immunity.

Wijesundara DK, Tscharke DC, Jackson RJ, Ranasinghe C.

PLoS One. 2013;8(1):e55788. doi: 10.1371/journal.pone.0055788. Epub 2013 Jan 31.


The current status of vertebrate cellular mRNA IRESs.

Jackson RJ.

Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2). pii: a011569. doi: 10.1101/cshperspect.a011569. Review.


Defining the roles and interactions of PTB.

Kafasla P, Mickleburgh I, Llorian M, Coelho M, Gooding C, Cherny D, Joshi A, Kotik-Kogan O, Curry S, Eperon IC, Jackson RJ, Smith CW.

Biochem Soc Trans. 2012 Aug;40(4):815-20. doi: 10.1042/BST20120044. Review.


Mobility and aging: new directions for public health action.

Satariano WA, Guralnik JM, Jackson RJ, Marottoli RA, Phelan EA, Prohaska TR.

Am J Public Health. 2012 Aug;102(8):1508-15. doi: 10.2105/AJPH.2011.300631. Epub 2012 Jun 14. Review.


Role of novel type I interferon epsilon in viral infection and mucosal immunity.

Xi Y, Day SL, Jackson RJ, Ranasinghe C.

Mucosal Immunol. 2012 Nov;5(6):610-22. doi: 10.1038/mi.2012.35. Epub 2012 May 23.

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