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Advanced glycation end products-related modulation of cathepsin L and NF-κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα.

Sharif U, Mahmud NM, Kay P, Yang YC, Harding SP, Grierson I, Kamalden TA, Jackson MJ, Paraoan L.

J Cell Mol Med. 2018 Oct 19. doi: 10.1111/jcmm.13944. [Epub ahead of print]


Developing a toolkit for the assessment and monitoring of musculoskeletal ageing.

Kemp GJ, Birrell F, Clegg PD, Cuthbertson DJ, De Vito G, van Dieën JH, Del Din S, Eastell R, Garnero P, Goljanek-Whysall K, Hackl M, Hodgson R, Jackson MJ, Lord S, Mazzà C, McArdle A, McCloskey EV, Narici M, Peffers MJ, Schiaffino S, Mathers JC.

Age Ageing. 2018 Sep 1;47(suppl_4):iv1-iv19. doi: 10.1093/ageing/afy143.


Towards a toolkit for the assessment and monitoring of musculoskeletal ageing.

Kemp GJ, Jackson MJ, McCloskey EV, Mathers JC; CIMA Toolkit Working Group.

Age Ageing. 2018 Nov 1;47(6):774-777. doi: 10.1093/ageing/afy078.


Redox responses are preserved across muscle fibres with differential susceptibility to aging.

Smith NT, Soriano-Arroquia A, Goljanek-Whysall K, Jackson MJ, McDonagh B.

J Proteomics. 2018 Apr 15;177:112-123. doi: 10.1016/j.jprot.2018.02.015. Epub 2018 Feb 10.


The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson's disease.

Fisher R, Lincoln L, Jackson MJ, Abbate V, Jenner P, Hider R, Lees A, Rose S.

Phytother Res. 2018 Apr;32(4):678-687. doi: 10.1002/ptr.6017. Epub 2018 Jan 24.


Selective placement of autogenous arteriovenous fistulae in an over 80-year-old population.

Werner-Gibbings K, Ischia L, Butcher W, Ward-Harvey R, Stewart J, Jackson MJ.

J Vasc Access. 2018 Jan;19(1):40-44. doi: 10.5301/jva.5000807.


Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle.

Sakellariou GK, McDonagh B, Porter H, Giakoumaki II, Earl KE, Nye GA, Vasilaki A, Brooks SV, Richardson A, Van Remmen H, McArdle A, Jackson MJ.

Antioxid Redox Signal. 2018 Feb 1;28(4):275-295. doi: 10.1089/ars.2017.7249. Epub 2017 Dec 12.


Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing.

Vasilaki A, Richardson A, Van Remmen H, Brooks SV, Larkin L, McArdle A, Jackson MJ.

J Physiol. 2017 Oct 15;595(20):6409-6415. doi: 10.1113/JP274336. Epub 2017 Sep 10. Review.


MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation.

Mercatelli N, Fittipaldi S, De Paola E, Dimauro I, Paronetto MP, Jackson MJ, Caporossi D.

Sci Rep. 2017 Aug 3;7(1):7219. doi: 10.1038/s41598-017-07575-0.


Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging.

Pollock N, Staunton CA, Vasilaki A, McArdle A, Jackson MJ.

Free Radic Biol Med. 2017 Nov;112:84-92. doi: 10.1016/j.freeradbiomed.2017.07.017. Epub 2017 Jul 21.


Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease.

Modo M, Crum WR, Gerwig M, Vernon AC, Patel P, Jackson MJ, Rose S, Jenner P, Iravani MM.

PLoS One. 2017 Jul 24;12(7):e0180733. doi: 10.1371/journal.pone.0180733. eCollection 2017.


The role of attenuated redox and heat shock protein responses in the age-related decline in skeletal muscle mass and function.

McArdle A, Jackson MJ.

Essays Biochem. 2017 Jul 11;61(3):339-348. doi: 10.1042/EBC20160088. Print 2017 Jul 15. Review.


Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia.

Pritchard S, Jackson MJ, Hikima A, Lione L, Benham CD, Chaudhuri KR, Rose S, Jenner P, Iravani MM.

PLoS One. 2017 May 17;12(5):e0175797. doi: 10.1371/journal.pone.0175797. eCollection 2017.


A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse.

Deepa SS, Bhaskaran S, Espinoza S, Brooks SV, McArdle A, Jackson MJ, Van Remmen H, Richardson A.

Geroscience. 2017 Apr;39(2):187-198. doi: 10.1007/s11357-017-9975-9. Epub 2017 Apr 13.


Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.

Sakellariou GK, Pearson T, Lightfoot AP, Nye GA, Wells N, Giakoumaki II, Griffiths RD, McArdle A, Jackson MJ.

FASEB J. 2016 Nov;30(11):3771-3785. Epub 2016 Aug 22.


Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy.

Sakellariou GK, Pearson T, Lightfoot AP, Nye GA, Wells N, Giakoumaki II, Vasilaki A, Griffiths RD, Jackson MJ, McArdle A.

Sci Rep. 2016 Sep 29;6:33944. doi: 10.1038/srep33944.


Casting a wider net in behavioral health screening in primary care: a preliminary study of the Outcome Rating Scale.

DeSantis B, Jackson MJ, Duncan BL, Reese RJ.

Prim Health Care Res Dev. 2017 Mar;18(2):188-193. doi: 10.1017/S1463423616000311. Epub 2016 Sep 9.


Incorporating X-ray summing into gamma-gamma signature quantification.

Britton R, Jackson MJ, Davies AV.

Appl Radiat Isot. 2016 Oct;116:128-33. doi: 10.1016/j.apradiso.2016.07.019. Epub 2016 Jul 21.


The effect of lengthening contractions on neuromuscular junction structure in adult and old mice.

Vasilaki A, Pollock N, Giakoumaki I, Goljanek-Whysall K, Sakellariou GK, Pearson T, Kayani A, Jackson MJ, McArdle A.

Age (Dordr). 2016 Aug;38(4):259-272. doi: 10.1007/s11357-016-9937-7. Epub 2016 Jul 29.


Reactive oxygen species in sarcopenia: Should we focus on excess oxidative damage or defective redox signalling?

Jackson MJ.

Mol Aspects Med. 2016 Aug;50:33-40. doi: 10.1016/j.mam.2016.05.002. Epub 2016 May 6. Review.


The Essential Role of Educator Development: 10 Years of the ACC Emerging Faculty Program.

Auseon AJ, O'Gara PT, Klodas E, Holmes DR Jr, Jackson MJ, Green JS, Konstam MA, Nishimura RA.

J Am Coll Cardiol. 2016 May 10;67(18):2177-2182. doi: 10.1016/j.jacc.2016.02.052. Review.


Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets.

Lincoln L, Fisher R, Jackson MJ, Jenner P, Neumeyer J, Sromek AW, Lees AJ, Rose S.

Mov Disord. 2016 Sep;31(9):1381-8. doi: 10.1002/mds.26626. Epub 2016 May 2. Review.


Recent advances and long-standing problems in detecting oxidative damage and reactive oxygen species in skeletal muscle.

Jackson MJ.

J Physiol. 2016 Sep 15;594(18):5185-93. doi: 10.1113/JP270657. Epub 2016 May 7. Review.


Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes.

Ford CT, Richardson S, McArdle F, Lotito SB, Crozier A, McArdle A, Jackson MJ.

Br J Nutr. 2016 May 28;115(10):1699-710. doi: 10.1017/S0007114516000805. Epub 2016 Mar 17.


Cellular mechanisms underlying oxidative stress in human exercise.

Jackson MJ, Vasilaki A, McArdle A.

Free Radic Biol Med. 2016 Sep;98:13-17. doi: 10.1016/j.freeradbiomed.2016.02.023. Epub 2016 Feb 18. Review.


Characterization of Supersaturated Danazol Solutions - Impact of Polymers on Solution Properties and Phase Transitions.

Jackson MJ, Kestur US, Hussain MA, Taylor LS.

Pharm Res. 2016 May;33(5):1276-88. doi: 10.1007/s11095-016-1871-y. Epub 2016 Feb 18.


Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage.

McDonagh B, Scullion SM, Vasilaki A, Pollock N, McArdle A, Jackson MJ.

Free Radic Biol Med. 2016 May;94:27-35. doi: 10.1016/j.freeradbiomed.2016.02.008. Epub 2016 Feb 10.


Perioperative management of diabetes in elective patients: a region-wide audit.

Jackson MJ, Patvardhan C, Wallace F, Martin A, Yusuff H, Briggs G, Malik RA; NWRAG Peri-Op Diabetes Audit Group.

Br J Anaesth. 2016 Apr;116(4):501-6. doi: 10.1093/bja/aev554. Epub 2016 Feb 11.


Role of reactive oxygen species in age-related neuromuscular deficits.

Jackson MJ, McArdle A.

J Physiol. 2016 Apr 15;594(8):1979-88. doi: 10.1113/JP270564. Review.


Diagnosing brain death.

Jackson MJ, Coleman L, Wilson A, Hanison J, Horner D; North West Research and Audit Group Journal Club.

Anaesthesia. 2016 Feb;71(2):232. doi: 10.1111/anae.13337. No abstract available.


Dissolution of Danazol Amorphous Solid Dispersions: Supersaturation and Phase Behavior as a Function of Drug Loading and Polymer Type.

Jackson MJ, Kestur US, Hussain MA, Taylor LS.

Mol Pharm. 2016 Jan 4;13(1):223-31. doi: 10.1021/acs.molpharmaceut.5b00652. Epub 2015 Dec 9.


Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers.

Rylance J, Chimpini C, Semple S, Russell DG, Jackson MJ, Heyderman RS, Gordon SB.

PLoS One. 2015 Sep 25;10(9):e0138762. doi: 10.1371/journal.pone.0138762. eCollection 2015.


SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes.

Lightfoot AP, Sakellariou GK, Nye GA, McArdle F, Jackson MJ, Griffiths RD, McArdle A.

Redox Biol. 2015 Dec;6:253-9. doi: 10.1016/j.redox.2015.08.007. Epub 2015 Aug 10.


Quantifying radionuclide signatures from a γ-γ coincidence system.

Britton R, Jackson MJ, Davies AV.

J Environ Radioact. 2015 Nov;149:158-63. doi: 10.1016/j.jenvrad.2015.07.025. Epub 2015 Aug 4.


Redox proteomic analysis of the gastrocnemius muscle from adult and old mice.

McDonagh B, Sakellariou GK, Smith NT, Brownridge P, Jackson MJ.

Data Brief. 2015 Jul 2;4:344-8. doi: 10.1016/j.dib.2015.06.012. eCollection 2015 Sep.


Intermittent self-dilatation for urethral stricture disease in males: A systematic review and meta-analysis.

Ivaz SL, Veeratterapillay R, Jackson MJ, Harding CK, Dorkin TJ, Andrich DE, Mundy AR.

Neurourol Urodyn. 2016 Sep;35(7):759-63. doi: 10.1002/nau.22803. Epub 2015 Jun 11. Review.


Alpha B-crystallin induction in skeletal muscle cells under redox imbalance is mediated by a JNK-dependent regulatory mechanism.

Fittipaldi S, Mercatelli N, Dimauro I, Jackson MJ, Paronetto MP, Caporossi D.

Free Radic Biol Med. 2015 Sep;86:331-42. doi: 10.1016/j.freeradbiomed.2015.05.035. Epub 2015 Jun 9.


In the idiopathic inflammatory myopathies (IIM), do reactive oxygen species (ROS) contribute to muscle weakness?

Lightfoot AP, McArdle A, Jackson MJ, Cooper RG.

Ann Rheum Dis. 2015 Jul;74(7):1340-6. doi: 10.1136/annrheumdis-2014-207172. Epub 2015 Apr 28. Review.


A high-efficiency HPGe coincidence system for environmental analysis.

Britton R, Davies AV, Burnett JL, Jackson MJ.

J Environ Radioact. 2015 Aug;146:1-5. doi: 10.1016/j.jenvrad.2015.03.033. Epub 2015 Apr 11.


Quality and length of life, money and urethral stricture disease.

Jackson MJ, Ivaz SL.

Curr Opin Urol. 2015 Jul;25(4):346-51. doi: 10.1097/MOU.0000000000000179. Review.


Redox regulation of muscle adaptations to contractile activity and aging.

Jackson MJ.

J Appl Physiol (1985). 2015 Aug 1;119(3):163-71. doi: 10.1152/japplphysiol.00760.2014. Epub 2015 Mar 19. Review.


Age affects the contraction-induced mitochondrial redox response in skeletal muscle.

Claflin DR, Jackson MJ, Brooks SV.

Front Physiol. 2015 Feb 4;6:21. doi: 10.3389/fphys.2015.00021. eCollection 2015.


Does fasting time alter fluid responsiveness after induction of anaesthesia?

Wythe S, Hanison J, Lund K, Aseri S, Shorrock P, Williams B, Jackson MJ; NWRAG.

Br J Anaesth. 2015 Mar;114(3):533. doi: 10.1093/bja/aev025. No abstract available.


Avoiding awareness in Caesarean sections under general anaesthesia.

Jackson MJ, McCormack V, Shorrock P, Lie J, Hanison J, Baylis C, Leech M, Scott A, Plummer N, Blomeley S.

Br J Anaesth. 2015 Mar;114(3):530-1. doi: 10.1093/bja/aev020. No abstract available.


Intermittent self-dilatation for urethral stricture disease in males.

Jackson MJ, Veeratterapillay R, Harding CK, Dorkin TJ.

Cochrane Database Syst Rev. 2014 Dec 19;(12):CD010258. doi: 10.1002/14651858.CD010258.pub2. Review.


Nitric oxide availability is increased in contracting skeletal muscle from aged mice, but does not differentially decrease muscle superoxide.

Pearson T, McArdle A, Jackson MJ.

Free Radic Biol Med. 2015 Jan;78:82-8. doi: 10.1016/j.freeradbiomed.2014.10.505. Epub 2014 Oct 22.


Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging.

McDonagh B, Sakellariou GK, Smith NT, Brownridge P, Jackson MJ.

J Proteome Res. 2014 Nov 7;13(11):5008-21. doi: 10.1021/pr5006394. Epub 2014 Sep 16.


Application of redox proteomics to skeletal muscle aging and exercise.

McDonagh B, Sakellariou GK, Jackson MJ.

Biochem Soc Trans. 2014 Aug;42(4):965-70. doi: 10.1042/BST20140085. Review.


Impact of polymers on the precipitation behavior of highly supersaturated aqueous danazol solutions.

Jackson MJ, Toth SJ, Kestur US, Huang J, Qian F, Hussain MA, Simpson GJ, Taylor LS.

Mol Pharm. 2014 Sep 2;11(9):3027-38. doi: 10.1021/mp500201s. Epub 2014 Aug 14.


Concise guidance: diagnosis and management of the epilepsies in adults.

Jackson MJ.

Clin Med (Lond). 2014 Aug;14(4):422-7. doi: 10.7861/clinmedicine.14-4-422.


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