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Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates.

Gardner AF, Jackson KM, Boyle MM, Buss JA, Potapov V, Gehring AM, Zatopek KM, Corrêa IR Jr, Ong JL, Jack WE.

Front Mol Biosci. 2019 Apr 24;6:28. doi: 10.3389/fmolb.2019.00028. eCollection 2019. Review.


Cash on delivery: Results of a randomized experiment to promote maternal health care in Kenya.

Grépin KA, Habyarimana J, Jack W.

J Health Econ. 2019 May;65:15-30. doi: 10.1016/j.jhealeco.2018.12.001. Epub 2019 Feb 18.


The Stressed Executive: Sources and Predictors of Stress Among Participants in an Executive Health Program.

Ganesh R, Mahapatra S, Fuehrer DL, Folkert LJ, Jack WA, Jenkins SM, Bauer BA, Wahner-Roedler DL, Sood A.

Glob Adv Health Med. 2018 Oct 17;7:2164956118806150. doi: 10.1177/2164956118806150. eCollection 2018.


Effect of community health clubs on child diarrhoea in western Rwanda: cluster-randomised controlled trial.

Sinharoy SS, Schmidt WP, Wendt R, Mfura L, Crossett E, Grépin KA, Jack W, Rwabufigiri BN, Habyarimana J, Clasen T.

Lancet Glob Health. 2017 Jul;5(7):e699-e709. doi: 10.1016/S2214-109X(17)30217-6.


The long-run poverty and gender impacts of mobile money.

Suri T, Jack W.

Science. 2016 Dec 9;354(6317):1288-1292. Epub 2016 Dec 8.


Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series.

Green AR, Soria D, Stephen J, Powe DG, Nolan CC, Kunkler I, Thomas J, Kerr GR, Jack W, Cameron D, Piper T, Ball GR, Garibaldi JM, Rakha EA, Bartlett JM, Ellis IO.

J Pathol Clin Res. 2016 Jan 15;2(1):32-40. doi: 10.1002/cjp2.32. eCollection 2016 Jan.


Child diarrhoea and nutritional status in rural Rwanda: a cross-sectional study to explore contributing environmental and demographic factors.

Sinharoy SS, Schmidt WP, Cox K, Clemence Z, Mfura L, Wendt R, Boisson S, Crossett E, Grépin KA, Jack W, Condo J, Habyarimana J, Clasen T.

Trop Med Int Health. 2016 Aug;21(8):956-964. doi: 10.1111/tmi.12725. Epub 2016 Jun 16.


Results of a large-scale randomized behavior change intervention on road safety in Kenya.

Habyarimana J, Jack W.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4661-70. doi: 10.1073/pnas.1422009112. Epub 2015 Aug 10.


FKBPL: a marker of good prognosis in breast cancer.

Nelson L, McKeen HD, Marshall A, Mulrane L, Starczynski J, Storr SJ, Lanigan F, Byrne C, Arthur K, Hegarty S, Ali AA, Furlong F, McCarthy HO, Ellis IO, Green AR, Rakha E, Young L, Kunkler I, Thomas J, Jack W, Cameron D, Jirström K, Yakkundi A, McClements L, Martin SG, Gallagher WM, Dunn J, Bartlett J, O'Connor D, Robson T.

Oncotarget. 2015 May 20;6(14):12209-23.


Correction to Lancet Oncol 2015; 16: 266.

Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM; PRIME II investigators.

Lancet Oncol. 2015 Mar;16(3):e105. doi: 10.1016/S1470-2045(15)70094-X. No abstract available.


Impact of intermittent preventive treatment in pregnancy with azithromycin-containing regimens on maternal nasopharyngeal carriage and antibiotic sensitivity of Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus: a cross-sectional survey at delivery.

Unger HW, Aho C, Ome-Kaius M, Wangnapi RA, Umbers AJ, Jack W, Lafana A, Michael A, Hanieh S, Siba P, Mueller I, Greenhill AR, Rogerson SJ.

J Clin Microbiol. 2015 Apr;53(4):1317-23. doi: 10.1128/JCM.03570-14. Epub 2015 Feb 11.


Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial.

Kunkler IH, Williams LJ, Jack WJ, Cameron DA, Dixon JM; PRIME II investigators.

Lancet Oncol. 2015 Mar;16(3):266-73. doi: 10.1016/S1470-2045(14)71221-5. Epub 2015 Jan 28. Erratum in: Lancet Oncol. 2015 Mar;16(3):e105.


Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer.

Stephen J, Murray G, Cameron DA, Thomas J, Kunkler IH, Jack W, Kerr GR, Piper T, Brookes CL, Rea DW, van de Velde CJ, Hasenburg A, Markopoulos C, Dirix L, Seynaeve C, Bartlett JM.

Br J Cancer. 2014 Dec 9;111(12):2242-7. doi: 10.1038/bjc.2014.530. Epub 2014 Oct 14.


A Morbidity Screening Tool for identifying fatigue, pain, upper limb dysfunction and lymphedema after breast cancer treatment: a validity study.

Bulley C, Coutts F, Blyth C, Jack W, Chetty U, Barber M, Tan CW.

Eur J Oncol Nurs. 2014 Apr;18(2):218-27. doi: 10.1016/j.ejon.2013.10.006. Epub 2013 Nov 15.


Comparison of breast cancer-related lymphedema (upper limb swelling) prevalence estimated using objective and subjective criteria and relationship with quality of life.

Bulley C, Gaal S, Coutts F, Blyth C, Jack W, Chetty U, Barber M, Tan CW.

Biomed Res Int. 2013;2013:807569. doi: 10.1155/2013/807569. Epub 2013 Jun 18.


Authors' reply.

Spears M, Cunningham CA, Taylor KJ, Mallon EA, Thomas JS, Kerr GR, Jack WJ, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

J Pathol. 2013 Feb;229(3):e2-3. doi: 10.1002/path.4144. No abstract available.


GSK3β and cyclin D1 expression predicts outcome in early breast cancer patients.

Quintayo MA, Munro AF, Thomas J, Kunkler IH, Jack W, Kerr GR, Dixon JM, Chetty U, Bartlett JM.

Breast Cancer Res Treat. 2012 Nov;136(1):161-8. doi: 10.1007/s10549-012-2229-8. Epub 2012 Sep 14.


Documenting the birth of a financial economy.

Suri T, Jack W, Stoker TM.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10257-62. doi: 10.1073/pnas.1115843109. Epub 2012 Jun 11.


Glad to be retiring.

Jack WA.

Br Dent J. 2012 May 11;212(9):407. doi: 10.1038/sj.bdj.2012.396. No abstract available.


Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.

Gardner AF, Wang J, Wu W, Karouby J, Li H, Stupi BP, Jack WE, Hersh MN, Metzker ML.

Nucleic Acids Res. 2012 Aug;40(15):7404-15. doi: 10.1093/nar/gks330. Epub 2012 May 8.


Expression of activated type I receptor tyrosine kinases in early breast cancer.

Spears M, Pederson HC, Lyttle N, Gray C, Quintayo MA, Brogan L, J Thomas JS, Kerr GR, Jack WJ, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

Breast Cancer Res Treat. 2012 Jul;134(2):701-8. doi: 10.1007/s10549-012-2076-7. Epub 2012 May 5.


Proximity ligation assays for isoform-specific Akt activation in breast cancer identify activated Akt1 as a driver of progression.

Spears M, Cunningham CA, Taylor KJ, Mallon EA, Thomas JS, Kerr GR, Jack WJ, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

J Pathol. 2012 Aug;227(4):481-9. doi: 10.1002/path.4022. Epub 2012 Apr 30.


Impact of screening and risk factors for local recurrence and survival after conservative surgery and radiotherapy for early breast cancer: results from a large series with long-term follow-up.

Kunkler IH, Kerr GR, Thomas JS, Jack WJ, Bartlett JM, Pedersen HC, Cameron DA, Dixon JM, Chetty U; Edinburgh Breast Group.

Int J Radiat Oncol Biol Phys. 2012 Jul 1;83(3):829-38. doi: 10.1016/j.ijrobp.2011.08.018. Epub 2011 Dec 22.


Polbase: a repository of biochemical, genetic and structural information about DNA polymerases.

Langhorst BW, Jack WE, Reha-Krantz L, Nichols NM.

Nucleic Acids Res. 2012 Jan;40(Database issue):D381-7. doi: 10.1093/nar/gkr847. Epub 2011 Oct 12.


The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews registry database analyses and economic evaluation.

Robertson C, Arcot Ragupathy SK, Boachie C, Dixon JM, Fraser C, Hernández R, Heys S, Jack W, Kerr GR, Lawrence G, MacLennan G, Maxwell A, McGregor J, Mowatt G, Pinder S, Ternent L, Thomas RE, Vale L, Wilson R, Zhu S, Gilbert FJ.

Health Technol Assess. 2011 Sep;15(34):v-vi, 1-322. doi: 10.3310/hta15340. Review.


Biochemical characterization of a structure-specific resolving enzyme from Sulfolobus islandicus rod-shaped virus 2.

Gardner AF, Guan C, Jack WE.

PLoS One. 2011;6(8):e23668. doi: 10.1371/journal.pone.0023668. Epub 2011 Aug 17.


Characterization of Sulfolobus islandicus rod-shaped virus 2 gp19, a single-strand specific endonuclease.

Gardner AF, Prangishvili D, Jack WE.

Extremophiles. 2011 Sep;15(5):619-24. doi: 10.1007/s00792-011-0385-0. Epub 2011 Jun 11.


The p160 ER co-regulators predict outcome in ER negative breast cancer.

Spears M, Oesterreich S, Migliaccio I, Guiterrez C, Hilsenbeck S, Quintayo MA, Pedraza J, Munro AF, Thomas JS, Kerr GR, Jack WJ, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

Breast Cancer Res Treat. 2012 Jan;131(2):463-72. doi: 10.1007/s10549-011-1426-1. Epub 2011 Mar 9.


A randomised controlled trial of post-operative radiotherapy following breast-conserving surgery in a minimum-risk population. Quality of life at 5 years in the PRIME trial.

Williams LJ, Kunkler IH, King CC, Jack W, van der Pol M.

Health Technol Assess. 2011 Mar;15(12):i-xi, 1-57. doi: 10.3310/hta15120.


Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial.

Lester RT, Ritvo P, Mills EJ, Kariri A, Karanja S, Chung MH, Jack W, Habyarimana J, Sadatsafavi M, Najafzadeh M, Marra CA, Estambale B, Ngugi E, Ball TB, Thabane L, Gelmon LJ, Kimani J, Ackers M, Plummer FA.

Lancet. 2010 Nov 27;376(9755):1838-45. doi: 10.1016/S0140-6736(10)61997-6. Epub 2010 Nov 9.


Intraoperative radiotherapy for early breast cancer.

Cameron D, Kunkler I, Dixon M, Jack W, Thomas J, Kerr G.

Lancet. 2010 Oct 2;376(9747):1142; author reply 1143-4. doi: 10.1016/S0140-6736(10)61532-2. No abstract available.


Incentives could induce Ethiopian doctors and nurses to work in rural settings.

Hanson K, Jack W.

Health Aff (Millwood). 2010 Aug;29(8):1452-60. doi: 10.1377/hlthaff.2009.0164.


Mammostrat as a tool to stratify breast cancer patients at risk of recurrence during endocrine therapy.

Bartlett JM, Thomas J, Ross DT, Seitz RS, Ring BZ, Beck RA, Pedersen HC, Munro A, Kunkler IH, Campbell FM, Jack W, Kerr GR, Johnstone L, Cameron DA, Chetty U.

Breast Cancer Res. 2010;12(4):R47. doi: 10.1186/bcr2604. Epub 2010 Jul 8.


Histological grading of invasive breast carcinoma--a simplification of existing methods in a large conservation series with long-term follow-up.

Thomas JS, Kerr GR, Jack WJ, Campbell F, McKay L, Pedersen HC, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

Histopathology. 2009 Dec;55(6):724-31. doi: 10.1111/j.1365-2559.2009.03429.x.


The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol.

Lester RT, Mills EJ, Kariri A, Ritvo P, Chung M, Jack W, Habyarimana J, Karanja S, Barasa S, Nguti R, Estambale B, Ngugi E, Ball TB, Thabane L, Kimani J, Gelmon L, Ackers M, Plummer FA.

Trials. 2009 Sep 22;10:87. doi: 10.1186/1745-6215-10-87.


Hygiene controls.

Ewart JM, Jack WA, Jack AA.

Br Dent J. 2009 Jul 11;207(1):5. doi: 10.1038/sj.bdj.2009.564. No abstract available.


Undesirable rhythms.

Jack WA.

Br Dent J. 2009 Feb 14;206(3):117. doi: 10.1038/sj.bdj.2009.65. No abstract available.


Breast radiotherapy: considerations in older patients.

Kunkler IH, Williams LJ, King CC, Jack W.

Clin Oncol (R Coll Radiol). 2009 Mar;21(2):111-7. doi: 10.1016/j.clon.2008.11.012. Epub 2009 Jan 4.


A randomised controlled trial of postoperative radiotherapy following breast-conserving surgery in a minimum-risk older population. The PRIME trial.

Prescott RJ, Kunkler IH, Williams LJ, King CC, Jack W, van der Pol M, Goh TT, Lindley R, Cairns J.

Health Technol Assess. 2007 Aug;11(31):1-149, iii-iv.


Health care costs for the treatment of breast cancer recurrent events: estimates from a UK-based patient-level analysis.

Karnon J, Kerr GR, Jack W, Papo NL, Cameron DA.

Br J Cancer. 2007 Aug 20;97(4):479-85. Epub 2007 Jul 24.


Changing pattern of the detection of locoregional relapse in breast cancer: the Edinburgh experience.

Montgomery DA, Krupa K, Jack WJ, Kerr GR, Kunkler IH, Thomas J, Dixon JM.

Br J Cancer. 2007 Jun 18;96(12):1802-7. Epub 2007 May 29.


Combination blue dye sentinel lymph node biopsy and axillary node sampling: the Edinburgh experience.

Chetty U, Chin PK, Soon PH, Jack W, Thomas JS; Edinburgh Breast Unit.

Eur J Surg Oncol. 2008 Jan;34(1):13-6. Epub 2007 May 11.


Optimal risk adjustment with adverse selection and spatial competition.

Jack W.

J Health Econ. 2006 Sep;25(5):908-26. Epub 2006 May 19.


Purchasing health care services from providers with unknown altruism.

Jack W.

J Health Econ. 2005 Jan;24(1):73-93.


What is the evidence for a reduced risk of local recurrence with age among older patients treated by breast conserving therapy?

Kunkler IH, King CC, Williams IJ, Prescott RJ, Jack W.

Breast. 2001 Dec;10(6):464-9.


Diagnostic delay in breast cancer.

Barber MD, Jack W, Dixon JM.

Br J Surg. 2004 Jan;91(1):49-53.


Comparative kinetics of nucleotide analog incorporation by vent DNA polymerase.

Gardner AF, Joyce CM, Jack WE.

J Biol Chem. 2004 Mar 19;279(12):11834-42. Epub 2003 Dec 29.


Falling short of expectations: public health interventions in developing and transition economies.

Jack W, Lewis M.

Soc Sci Med. 2004 Jan;58(2):223-5. No abstract available.


Contracting for health services: an evaluation of recent reforms in Nicaragua.

Jack W.

Health Policy Plan. 2003 Jun;18(2):195-204.


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