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In Situ Gel of Triamcinolone Acetonide-Loaded Solid Lipid Nanoparticles for Improved Topical Ocular Delivery: Tear Kinetics and Ocular Disposition Studies.

Tatke A, Dudhipala N, Janga KY, Balguri SP, Avula B, Jablonski MM, Majumdar S.

Nanomaterials (Basel). 2018 Dec 27;9(1). pii: E33. doi: 10.3390/nano9010033.


The long-term effects of gene therapy in a novel mouse model of human MFRP-associated retinopathy.

Chekuri A, Sahu B, Chavali VRM, Voronchikhina M, Hermida AS, Suk JJ, Alapati AN, Bartsch DU, Ayala-Ramirez R, Zenteno JC, Dinculescu A, Jablonski MM, Borooah S, Ayyagari R.

Hum Gene Ther. 2018 Nov 30. doi: 10.1089/hum.2018.192. [Epub ahead of print]


Data sets of eQTL loci, correlation analysis, and overlapped genes among gene sets that their expression levels are closely related to genes of Vegf family.

Cui J, Li J, Lu H, Yu H, Wei D, Jiao Y, Jablonski MM, Gu W, Chen H.

Data Brief. 2018 Sep 8;20:1854-1860. doi: 10.1016/j.dib.2018.09.004. eCollection 2018 Oct.


Potential effect on molecular pathways in different targeted genes in the VEGF family in retina - From the genomic point of view.

Cui J, Liu L, Lu H, Wei D, Jiao Y, Jablonski MM, Williams RW, Gu W, Chen H.

Exp Eye Res. 2018 Nov;176:78-87. doi: 10.1016/j.exer.2018.06.024. Epub 2018 Jun 23.


Retina Compatible Interactions and Effective Modulation of Blood Ocular Barrier P-gp Activity by Third-Generation Inhibitors Improve the Ocular Penetration of Loperamide.

Janga KY, Tatke A, Shukla S, Lamichhane SP, Avula B, Wang X, Jablonski MM, Khan IA, Majumdar S.

J Pharm Sci. 2018 Aug;107(8):2128-2135. doi: 10.1016/j.xphs.2018.04.008. Epub 2018 Apr 17.


P-glycoprotein Restricts Ocular Penetration of Loperamide across the Blood-Ocular Barriers: a Comparative Study in Mdr1a Knock-out and Wild Type Sprague Dawley Rats.

Tatke A, Janga KY, Avula B, Wang X, Jablonski MM, Khan IA, Majumdar S.

AAPS PharmSciTech. 2018 May;19(4):1662-1671. doi: 10.1208/s12249-018-0979-2. Epub 2018 Mar 8.


Ion-sensitive in situ hydrogels of natamycin bilosomes for enhanced and prolonged ocular pharmacotherapy: in vitro permeability, cytotoxicity and in vivo evaluation.

Janga KY, Tatke A, Balguri SP, Lamichanne SP, Ibrahim MM, Maria DN, Jablonski MM, Majumdar S.

Artif Cells Nanomed Biotechnol. 2018 Feb 23:1-12. doi: 10.1080/21691401.2018.1443117. [Epub ahead of print]


Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility.

Chintalapudi SR, Maria D, Di Wang X, Bailey JNC; NEIGHBORHOOD consortium; International Glaucoma Genetics consortium, Hysi PG, Wiggs JL, Williams RW, Jablonski MM.

Nat Commun. 2017 Nov 24;8(1):1755. doi: 10.1038/s41467-017-00837-5.


Comparison of effectiveness and safety between conbercept and ranibizumab for treatment of neovascular age-related macular degeneration. A retrospective case-controlled non-inferiority multiple center study.

Cui J, Sun D, Lu H, Dai R, Xing L, Dong H, Wang L, Wei D, Jiang B, Jiao Y, Jablonski MM, Charles S, Gu W, Chen H.

Eye (Lond). 2018 Feb;32(2):391-399. doi: 10.1038/eye.2017.187. Epub 2017 Sep 22.


Current drug and molecular therapies for the treatment of atrophic age-related macular degeneration: phase I to phase III clinical development.

Li H, Chintalapudi SR, Jablonski MM.

Expert Opin Investig Drugs. 2017 Oct;26(10):1103-1114. doi: 10.1080/13543784.2017.1369042. Epub 2017 Aug 24. Review.


Isolation of Primary Murine Retinal Ganglion Cells (RGCs) by Flow Cytometry.

Chintalapudi SR, Patel NN, Goldsmith ZK, Djenderedjian L, Wang XD, Marion TN, Jablonski MM, Morales-Tirado VM.

J Vis Exp. 2017 Jul 5;(125). doi: 10.3791/55785.


Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome.

Godisela KK, Reddy SS, Kumar CU, Saravanan N, Reddy PY, Jablonski MM, Ayyagari R, Reddy GB.

Mol Vis. 2017 Apr 14;23:263-274. eCollection 2017.


Nimodipine Ophthalmic Formulations for Management of Glaucoma.

Maria DN, Abd-Elgawad AH, Soliman OA, El-Dahan MS, Jablonski MM.

Pharm Res. 2017 Apr;34(4):809-824. doi: 10.1007/s11095-017-2110-x. Epub 2017 Feb 2.


Systems Genetics Analysis to Identify the Genetic Modulation of a Glaucoma-Associated Gene.

Chintalapudi SR, Jablonski MM.

Methods Mol Biol. 2017;1488:391-417.


Genetic and immunohistochemical analysis of HSPA5 in mouse and human retinas.

Chintalapudi SR, Wang X, Li H, Lau YH, Williams RW, Jablonski MM.

Mol Vis. 2016 Nov 10;22:1318-1331. eCollection 2016.


Stability and Ocular Pharmacokinetics of Celecoxib-Loaded Nanoparticles Topical Ophthalmic Formulations.

Ibrahim MM, Abd-Elgawad AH, Soliman OA, Jablonski MM.

J Pharm Sci. 2016 Dec;105(12):3691-3701. doi: 10.1016/j.xphs.2016.09.019. Epub 2016 Oct 24.


Water-soluble Complex of Curcumin with Cyclodextrins: Enhanced Physical Properties For Ocular Drug Delivery.

Maria DN, Mishra SR, Wang L, Abd-Elgawad AH, Soliman OA, El-Dahan MS, Jablonski MM.

Curr Drug Deliv. 2017 Sep 6;14(6):875-886. doi: 10.2174/1567201813666160808111209.


Isolation and Molecular Profiling of Primary Mouse Retinal Ganglion Cells: Comparison of Phenotypes from Healthy and Glaucomatous Retinas.

Chintalapudi SR, Djenderedjian L, Stiemke AB, Steinle JJ, Jablonski MM, Morales-Tirado VM.

Front Aging Neurosci. 2016 May 18;8:93. doi: 10.3389/fnagi.2016.00093. eCollection 2016.


Poly(ortho ester) nanoparticles targeted for chronic intraocular diseases: ocular safety and localization after intravitreal injection.

Li H, Palamoor M, Jablonski MM.

Nanotoxicology. 2016 Oct;10(8):1152-9. doi: 10.1080/17435390.2016.1181808. Epub 2016 May 16.


Multipronged approach to identify and validate a novel upstream regulator of Sncg in mouse retinal ganglion cells.

Chintalapudi SR, Morales-Tirado VM, Williams RW, Jablonski MM.

FEBS J. 2016 Feb;283(4):678-93. doi: 10.1111/febs.13620. Epub 2016 Jan 18.


Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma.

Ibrahim MM, Abd-Elgawad AH, Soliman OA, Jablonski MM.

Transl Vis Sci Technol. 2015 Jun 30;4(3):12. eCollection 2015 Jun.


Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model.

Sahu B, Chavali VR, Alapati A, Suk J, Bartsch DU, Jablonski MM, Ayyagari R.

Mol Vis. 2015 Mar 13;21:273-84. eCollection 2015.


Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene.

Mary-Sinclair MN, Wang X, Swanson DJ, Sung CY, Mendonca EA, Wroblewski K, Baumer SH, Goldowitz D, Jablonski MM, Skapek SX.

Mol Vis. 2014 Mar 3;20:215-30. eCollection 2014.


Novel endogenous glycan therapy for retinal diseases: safety, in vitro stability, ocular pharmacokinetic modeling, and biodistribution.

Swaminathan S, Li H, Palamoor M, de Obarrio WT, Madhura D, Meibohm B, Jablonski MM.

AAPS J. 2014 Mar;16(2):311-23. doi: 10.1208/s12248-014-9563-1. Epub 2014 Jan 28.


Synthesis, characterization and in vitro studies of celecoxib-loaded poly(ortho ester) nanoparticles targeted for intraocular drug delivery.

Palamoor M, Jablonski MM.

Colloids Surf B Biointerfaces. 2013 Dec 1;112:474-82. doi: 10.1016/j.colsurfb.2013.07.039. Epub 2013 Jul 26.


Novel topical ophthalmic formulations for management of glaucoma.

Ibrahim MM, Abd-Elgawad AE, Soliman OA, Jablonski MM.

Pharm Res. 2013 Nov;30(11):2818-31. doi: 10.1007/s11095-013-1109-1. Epub 2013 Jun 15.


Genetic modulation of the iris transillumination defect: a systems genetics analysis using the expanded family of BXD glaucoma strains.

Swaminathan S, Lu H, Williams RW, Lu L, Jablonski MM.

Pigment Cell Melanoma Res. 2013 Jul;26(4):487-98. doi: 10.1111/pcmr.12106. Epub 2013 May 13.


Innate immune network in the retina activated by optic nerve crush.

Templeton JP, Freeman NE, Nickerson JM, Jablonski MM, Rex TS, Williams RW, Geisert EE.

Invest Ophthalmol Vis Sci. 2013 Apr 9;54(4):2599-606. doi: 10.1167/iovs.12-11175.


Nanoparticle-based topical ophthalmic formulations for sustained celecoxib release.

Ibrahim MM, Abd-Elgawad AE, Soliman OA, Jablonski MM.

J Pharm Sci. 2013 Mar;102(3):1036-53. doi: 10.1002/jps.23417. Epub 2013 Jan 3.


Poly(ortho ester) nanoparticle-based targeted intraocular therapy for controlled release of hydrophilic molecules.

Palamoor M, Jablonski MM.

Mol Pharm. 2013 Feb 4;10(2):701-8. doi: 10.1021/mp300488s. Epub 2013 Jan 7.


Complex interactions of Tyrp1 in the eye.

Lu H, Li L, Watson ER, Williams RW, Geisert EE, Jablonski MM, Lu L.

Mol Vis. 2011;17:2455-68. Epub 2011 Sep 22.


Genetic dissection of the Gpnmb network in the eye.

Lu H, Wang X, Pullen M, Guan H, Chen H, Sahu S, Zhang B, Chen H, Williams RW, Geisert EE, Lu L, Jablonski MM.

Invest Ophthalmol Vis Sci. 2011 Jun 13;52(7):4132-42. doi: 10.1167/iovs.10-6493.


A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration.

Chavali VR, Khan NW, Cukras CA, Bartsch DU, Jablonski MM, Ayyagari R.

Hum Mol Genet. 2011 May 15;20(10):2000-14. doi: 10.1093/hmg/ddr080. Epub 2011 Feb 24.


Genetic pathways regulating glutamate levels in retinal Müller cells.

Jablonski MM, Freeman NE, Orr WE, Templeton JP, Lu L, Williams RW, Geisert EE.

Neurochem Res. 2011 Apr;36(4):594-603. doi: 10.1007/s11064-010-0277-1. Epub 2010 Sep 30.


Cellular retinol binding protein 1 modulates photoreceptor outer segment folding in the isolated eye.

Wang X, Tong Y, Giorgianni F, Beranova-Giorgianni S, Penn JS, Jablonski MM.

Dev Neurobiol. 2010 Aug;70(9):623-35. doi: 10.1002/dneu.20798.


In search of the identity of the XAP-1 antigen: a protein localized to cone outer segments.

Nookala S, Gandrakota R, Wohabrebbi A, Wang X, Howell D, Giorgianni F, Beranova-Giorgianni S, Desiderio DM, Jablonski MM.

Invest Ophthalmol Vis Sci. 2010 May;51(5):2736-43. doi: 10.1167/iovs.09-4286. Epub 2009 Dec 30.


Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin.

Vasireddy V, Jablonski MM, Khan NW, Wang XF, Sahu P, Sparrow JR, Ayyagari R.

Exp Eye Res. 2009 Dec;89(6):905-12. doi: 10.1016/j.exer.2009.07.021. Epub 2009 Aug 13.


A novel rat model with obesity-associated retinal degeneration.

Reddy GB, Vasireddy V, Mandal MN, Tiruvalluru M, Wang XF, Jablonski MM, Nappanveettil G, Ayyagari R.

Invest Ophthalmol Vis Sci. 2009 Jul;50(7):3456-63. doi: 10.1167/iovs.08-2498. Epub 2009 Apr 15.


Proteomic analysis of the retina: removal of RPE alters outer segment assembly and retinal protein expression.

Wang X, Nookala S, Narayanan C, Giorgianni F, Beranova-Giorgianni S, McCollum G, Gerling I, Penn JS, Jablonski MM.

Glia. 2009 Mar;57(4):380-92. doi: 10.1002/glia.20765.


Contribution of Müller cells toward the regulation of photoreceptor outer segment assembly.

Wang X, Iannaccone A, Jablonski MM.

Neuron Glia Biol. 2004 Aug;1(3):291-6. doi: doi:10.1017/S1740925X05000049.


Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks.

Berry RB, Werner DF, Wang X, Jablonski MM, Homanics GE, Mittleman G, Matthews DB.

Neurobiol Learn Mem. 2008 Oct;90(3):580-3. doi: 10.1016/j.nlm.2008.06.004. Epub 2008 Jul 26.


Clinical and functional findings in choroideremia due to complete deletion of the CHM gene.

Mura M, Sereda C, Jablonski MM, MacDonald IM, Iannaccone A.

Arch Ophthalmol. 2007 Aug;125(8):1107-13.


Age-related decline in VIP-positive parasympathetic nerve fibers in the human submacular choroid.

Jablonski MM, Iannaccone A, Reynolds DH, Gallaher P, Allen S, Wang X, Reiner A.

Invest Ophthalmol Vis Sci. 2007 Feb;48(2):479-85.


Spatial and temporal expression of MFRP and its interaction with CTRP5.

Mandal MN, Vasireddy V, Jablonski MM, Wang X, Heckenlively JR, Hughes BA, Reddy GB, Ayyagari R.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5514-21.


CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion.

Mandal MN, Vasireddy V, Reddy GB, Wang X, Moroi SE, Pattnaik BR, Hughes BA, Heckenlively JR, Hitchcock PF, Jablonski MM, Ayyagari R.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5505-13.


Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration.

Vasireddy V, Jablonski MM, Mandal MN, Raz-Prag D, Wang XF, Nizol L, Iannaccone A, Musch DC, Bush RA, Salem N Jr, Sieving PA, Ayyagari R.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4558-68. Erratum in: Invest Ophthalmol Vis Sci. 2007 May;48(5):2083.


An unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutation.

Iannaccone A, Mura M, Dyka FM, Ciccarelli ML, Yashar BM, Ayyagari R, Jablonski MM, Molday RS.

Vision Res. 2006 Oct;46(22):3845-52. Epub 2006 Aug 1.


Early transposable element insertion in intron 9 of the Hsf4 gene results in autosomal recessive cataracts in lop11 and ldis1 mice.

Talamas E, Jackson L, Koeberl M, Jackson T, McElwee JL, Hawes NL, Chang B, Jablonski MM, Sidjanin DJ.

Genomics. 2006 Jul;88(1):44-51. Epub 2006 Apr 3.


Contribution of Müller cells toward the regulation of photoreceptor outer segment assembly.

Wang X, Iannaccone A, Jablonski MM.

Neuron Glia Biol. 2005 Jan;1:1-6.

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