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Items: 1 to 50 of 194


Case report: recurrent metastatic breast cancer in internal mammary dissection bed discovered at the time of coronary bypass.

Woodard GA, Lee H, Fels Elliott DR, Jones KD, Wong J, Jablons DM, Ihnken K.

J Cardiothorac Surg. 2019 Sep 5;14(1):158. doi: 10.1186/s13019-019-0980-1.


Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model.

Hsu PC, Tian B, Yang YL, Wang YC, Liu S, Urisman A, Yang CT, Xu Z, Jablons DM, You L.

Oncol Rep. 2019 Aug;42(2):697-707. doi: 10.3892/or.2019.7207. Epub 2019 Jun 20.


Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10.

Hung MS, Chen YC, Lin P, Li YC, Hsu CC, Lung JH, You L, Xu Z, Mao JH, Jablons DM, Yang CT.

Cancers (Basel). 2019 May 2;11(5). pii: E618. doi: 10.3390/cancers11050618.


Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging.

Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ.

J Thorac Oncol. 2019 Jul;14(7):1223-1232. doi: 10.1016/j.jtho.2019.03.015. Epub 2019 Apr 5.


Pathologic Complete Response to Neoadjuvant Crizotinib in a Lung Adenocarcinoma Patient With a MET Exon 14 Skipping Mutation.

Rotow JK, Woodard GA, Urisman A, McCoach CE, Bivona TG, Elicker BM, Jablons DM, Blakely CM.

Clin Lung Cancer. 2019 Mar;20(2):e137-e141. doi: 10.1016/j.cllc.2018.11.003. Epub 2018 Nov 20. No abstract available.


The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer.

Hsu PC, Yang CT, Jablons DM, You L.

Biomedicines. 2018 Dec 7;6(4). pii: E114. doi: 10.3390/biomedicines6040114. Review.


Central Airway Obstruction Due to Tracheal Glomus Tumor.

Haro GJ, Seeley EJ, Jablons DM, Kratz JR.

Thorac Cardiovasc Surg Rep. 2018 Jan;7(1):e43-e45. doi: 10.1055/s-0038-1675411. Epub 2018 Nov 20.


Scientific Advances and New Frontiers in Mesothelioma Therapeutics.

Mutti L, Peikert T, Robinson BWS, Scherpereel A, Tsao AS, de Perrot M, Woodard GA, Jablons DM, Wiens J, Hirsch FR, Yang H, Carbone M, Thomas A, Hassan R.

J Thorac Oncol. 2018 Sep;13(9):1269-1283. doi: 10.1016/j.jtho.2018.06.011. Review.


Transfer of multiple loci of donor's genes to induce recipient tolerance in organ transplantation.

Li T, Zhang W, Xu Q, Li S, Tong X, Ding J, Li H, Hou S, Xu Z, Jablons DM, You L.

Exp Ther Med. 2018 Jun;15(6):4961-4971. doi: 10.3892/etm.2018.6058. Epub 2018 Apr 13.


Old Sonic Hedgehog, new tricks: a new paradigm in thoracic malignancies.

Giroux Leprieur E, Jablons DM, He B.

Oncotarget. 2018 Feb 6;9(18):14680-14691. doi: 10.18632/oncotarget.24411. eCollection 2018 Mar 6. Review.


Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog.

Tolani B, Hoang NT, Acevedo LA, Giroux Leprieur E, Li H, He B, Jablons DM.

Oncotarget. 2018 Feb 16;9(18):14311-14323. doi: 10.18632/oncotarget.24510. eCollection 2018 Mar 6.


Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma.

Hsu PC, Miao J, Wang YC, Zhang WQ, Yang YL, Wang CW, Yang CT, Huang Z, You J, Xu Z, Jablons DM, You L.

J Cell Mol Med. 2018 Jun;22(6):3139-3148. doi: 10.1111/jcmm.13593. Epub 2018 Mar 24.


Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model.

Hsu PC, Miao J, Huang Z, Yang YL, Xu Z, You J, Dai Y, Yeh CC, Chan G, Liu S, Urisman A, Yang CT, Jablons DM, You L.

J Cell Mol Med. 2018 Jun;22(6):3073-3085. doi: 10.1111/jcmm.13582. Epub 2018 Mar 24.


Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma.

Wang L, Jin JQ, Zhou Y, Tian Z, Jablons DM, He B.

Oncotarget. 2017 Dec 1;9(1):853-865. doi: 10.18632/oncotarget.22856. eCollection 2018 Jan 2.


YAP regulates PD-L1 expression in human NSCLC cells.

Miao J, Hsu PC, Yang YL, Xu Z, Dai Y, Wang Y, Chan G, Huang Z, Hu B, Li H, Jablons DM, You L.

Oncotarget. 2017 Dec 9;8(70):114576-114587. doi: 10.18632/oncotarget.23051. eCollection 2017 Dec 29.


Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer.

Giroux Leprieur E, Tolani B, Li H, Leguay F, Hoang NT, Acevedo LA, Jin JQ, Tseng HH, Yue D, Kim IJ, Wislez M, Wang C, Jablons DM, He B.

Oncotarget. 2017 Oct 10;8(61):103744-103757. doi: 10.18632/oncotarget.21781. eCollection 2017 Nov 28.


Drug development against the hippo pathway in mesothelioma.

Woodard GA, Yang YL, You L, Jablons DM.

Transl Lung Cancer Res. 2017 Jun;6(3):335-342. doi: 10.21037/tlcr.2017.06.02. Review.


Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer.

Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM.

Clin Lung Cancer. 2018 Jan;19(1):58-64. doi: 10.1016/j.cllc.2017.05.015. Epub 2017 May 31.


DCLK1 is correlated with MET and ERK5 expression, and associated with prognosis in malignant pleural mesothelioma.

Wang H, Dai YY, Zhang WQ, Hsu PC, Yang YL, Wang YC, Chan G, Au A, Xu ZD, Jiang SJ, Wang W, Jablons DM, You L.

Int J Oncol. 2017 Jul;51(1):91-103. doi: 10.3892/ijo.2017.4021. Epub 2017 May 26.


Targeting YAP in malignant pleural mesothelioma.

Zhang WQ, Dai YY, Hsu PC, Wang H, Cheng L, Yang YL, Wang YC, Xu ZD, Liu S, Chan G, Hu B, Li H, Jablons DM, You L.

J Cell Mol Med. 2017 Nov;21(11):2663-2676. doi: 10.1111/jcmm.13182. Epub 2017 May 4.


Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device.

Yoon JH, Kim TW, Mendez P, Jablons DM, Kim IJ.

PLoS One. 2017 Apr 12;12(4):e0174696. doi: 10.1371/journal.pone.0174696. eCollection 2017.


Management of Lung Cancer Invading the Superior Sulcus.

Kratz JR, Woodard G, Jablons DM.

Thorac Surg Clin. 2017 May;27(2):149-157. doi: 10.1016/j.thorsurg.2017.01.008. Review.


YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells.

Dai Y, Liu S, Zhang WQ, Yang YL, Hang P, Wang H, Cheng L, Hsu PC, Wang YC, Xu Z, Jablons DM, You L.

Oncotarget. 2017 Jan 17;8(3):4096-4109. doi: 10.18632/oncotarget.13686.


Hybrid minimally invasive Ivor Lewis esophagectomy after neoadjuvant chemoradiation yields excellent long-term survival outcomes with minimal morbidity.

Woodard GA, Crockard JC, Clary-Macy C, Zoon-Besselink CT, Jones K, Korn WM, Ko AH, Gottschalk AR, Rogers SJ, Jablons DM.

J Surg Oncol. 2016 Dec;114(7):838-847. doi: 10.1002/jso.24409. Epub 2016 Aug 28.


FAIM2, as a novel diagnostic maker and a potential therapeutic target for small-cell lung cancer and atypical carcinoid.

Kang HC, Kim JI, Chang HK, Woodard G, Choi YS, Ku JL, Jablons DM, Kim IJ.

Sci Rep. 2016 Sep 28;6:34022. doi: 10.1038/srep34022.


Lung Cancer Staging and Prognosis.

Woodard GA, Jones KD, Jablons DM.

Cancer Treat Res. 2016;170:47-75. doi: 10.1007/978-3-319-40389-2_3. Review.


Development of a robust DNA quality and quantity assessment qPCR assay for targeted next-generation sequencing library preparation.

Dang J, Mendez P, Lee S, Kim JW, Yoon JH, Kim TW, Sailey CJ, Jablons DM, Kim IJ.

Int J Oncol. 2016 Oct;49(4):1755-65. doi: 10.3892/ijo.2016.3654. Epub 2016 Aug 11.


YAP promotes erlotinib resistance in human non-small cell lung cancer cells.

Hsu PC, You B, Yang YL, Zhang WQ, Wang YC, Xu Z, Dai Y, Liu S, Yang CT, Li H, Hu B, Jablons DM, You L.

Oncotarget. 2016 Aug 9;7(32):51922-51933. doi: 10.18632/oncotarget.10458.


Comprehensive evaluation and validation of targeted next-generation sequencing performance in two clinical laboratories.

Mendez P, Dang J, Kim JW, Lee S, Yoon JH, Kim T, Sailey CJ, Jablons DM, Kim IJ.

Int J Oncol. 2016 Jul;49(1):235-42. doi: 10.3892/ijo.2016.3497. Epub 2016 Apr 25.


Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells.

Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Lung JH, Yang CT, Liu ST.

J Cell Mol Med. 2016 Jul;20(7):1295-306. doi: 10.1111/jcmm.12811. Epub 2016 Mar 10.


SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer.

Lui NS, Yang YW, van Zante A, Buchanan P, Jablons DM, Lemjabbar-Alaoui H.

PLoS One. 2016 Feb 16;11(2):e0148911. doi: 10.1371/journal.pone.0148911. eCollection 2016.


Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas.

Kang HC, Kim HK, Lee S, Mendez P, Kim JW, Woodard G, Yoon JH, Jen KY, Fang LT, Jones K, Jablons DM, Kim IJ.

Oncotarget. 2016 Feb 16;7(7):8321-31. doi: 10.18632/oncotarget.7032.


Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells.

Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Hsieh MJ, Lin YC, Yang CT, Liu ST, Tsai YH.

Oncol Rep. 2015 Dec;34(6):3187-95.


Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene.

Wang Y, Xu Z, Mao JH, Hung MS, Hsieh D, Au A, Jablons DM, You L.

Thorac Cancer. 2015 Jul;6(4):480-7. doi: 10.1111/1759-7714.12257. Epub 2015 Jun 8.


Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma.

Yang YL, Ni J, Hsu PC, Mao JH, Hsieh D, Xu A, Chan G, Au A, Xu Z, Jablons DM, You L.

J Cell Mol Med. 2015 Oct;19(10):2385-96. doi: 10.1111/jcmm.12620. Epub 2015 Jul 27.


Operative and Perioperative Pulmonary Emboli.

Cox JC, Jablons DM.

Thorac Surg Clin. 2015 Aug;25(3):289-99. doi: 10.1016/j.thorsurg.2015.04.010. Epub 2015 Jun 12. Review.


EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas.

Yue D, Li H, Che J, Zhang Y, Tolani B, Mo M, Zhang H, Zheng Q, Yang Y, Cheng R, Jin JQ, Luh TW, Yang C, Tseng HH, Giroux-Leprieur E, Woodard GA, Hao X, Wang C, Jablons DM, He B.

PLoS One. 2015 Jul 1;10(7):e0132134. doi: 10.1371/journal.pone.0132134. eCollection 2015.


PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer.

Wang Y, Xu Z, Mao JH, Hsieh D, Au A, Jablons DM, Li H, You L.

Zhongguo Fei Ai Za Zhi. 2015 Jun;18(6):345-50. doi: 10.3779/j.issn.1009-3419.2015.06.15.


The Latest in Surgical Management of Stage IIIA Non-Small Cell Lung Cancer: Video-Assisted Thoracic Surgery and Tumor Molecular Profiling.

Woodard GA, Jablons DM.

Am Soc Clin Oncol Educ Book. 2015:e435-41. doi: 10.14694/EdBook_AM.2015.35.e435. Review.


NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.

Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, Krogan NJ, Bivona TG.

Cell Rep. 2015 Apr 7;11(1):98-110. doi: 10.1016/j.celrep.2015.03.012. Epub 2015 Apr 2.


Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14.

Letteboer TG, Benzinou M, Merrick CB, Quigley DA, Zhau K, Kim IJ, To MD, Jablons DM, van Amstel JK, Westermann CJ, Giraud S, Dupuis-Girod S, Lesca G, Berg JH, Balmain A, Akhurst RJ.

Front Genet. 2015 Mar 12;6:67. doi: 10.3389/fgene.2015.00067. eCollection 2015.


Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.

You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L.

Oncotarget. 2015 Feb 28;6(6):4357-68.


CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells.

Zhang S, Yang YL, Wang Y, You B, Dai Y, Chan G, Hsieh D, Kim IJ, Fang LT, Au A, Stoppler HJ, Xu Z, Jablons DM, You L.

J Exp Clin Cancer Res. 2014 Nov 25;33:93. doi: 10.1186/s13046-014-0093-6.


Measurement of genome-wide DNA methylation predicts survival benefits from chemotherapy in non-small cell lung cancer.

Mo ML, Ma J, Chen Z, Wei B, Li H, Zhou Y, Shi H, Tolani B, Jin JQ, Tseng HH, Shen D, Zhan Y, Li J, Jablons DM, Zhang RQ, Guo Y, He B, Zhou HM.

J Cancer Res Clin Oncol. 2015 May;141(5):901-8. doi: 10.1007/s00432-014-1860-7. Epub 2014 Nov 4.


Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma.

Capelletti M, Dodge ME, Ercan D, Hammerman PS, Park SI, Kim J, Sasaki H, Jablons DM, Lipson D, Young L, Stephens PJ, Miller VA, Lindeman NI, Munir KJ, Richards WG, Jänne PA.

Clin Cancer Res. 2014 Dec 15;20(24):6551-8. doi: 10.1158/1078-0432.CCR-14-1337. Epub 2014 Oct 7.


Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer.

Woodard GA, Gubens MA, Jahan TM, Jones KD, Kukreja J, Theodore PR, Cardozo S, Jew G, Clary-Macy C, Jablons DM, Mann MJ.

Clin Lung Cancer. 2014 Nov;15(6):426-32. doi: 10.1016/j.cllc.2014.07.004. Epub 2014 Aug 15.


The homeobox gene EMX2 is a prognostic and predictive marker in malignant pleural mesothelioma.

Giroux Leprieur E, Hirata T, Mo M, Chen Z, Okamoto J, Clement G, Li H, Wislez M, Jablons DM, He B.

Lung Cancer. 2014 Sep;85(3):465-71. doi: 10.1016/j.lungcan.2014.06.018. Epub 2014 Jun 30.


Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas.

Yue D, Li H, Che J, Zhang Y, Tseng HH, Jin JQ, Luh TM, Giroux-Leprieur E, Mo M, Zheng Q, Shi H, Zhang H, Hao X, Wang C, Jablons DM, He B.

J Exp Clin Cancer Res. 2014 Apr 24;33:34. doi: 10.1186/1756-9966-33-34.

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