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Items: 1 to 50 of 221

1.

Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic drive.

Odenthal-Hesse L, Berg IL, Veselis A, Jeffreys AJ, May CA.

PLoS Genet. 2014 Feb 6;10(2):e1004106. doi: 10.1371/journal.pgen.1004106. eCollection 2014 Feb.

2.

The man behind the DNA fingerprints: an interview with Professor Sir Alec Jeffreys.

Jeffreys AJ.

Investig Genet. 2013 Nov 18;4(1):21. doi: 10.1186/2041-2223-4-21.

3.

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome.

Huang Y, Hidalgo-Bravo A, Zhang E, Cotton VE, Mendez-Bermudez A, Wig G, Medina-Calzada Z, Neumann R, Jeffreys AJ, Winney B, Wilson JF, Clark DA, Dyer MJ, Royle NJ.

Nucleic Acids Res. 2014 Jan;42(1):315-27. doi: 10.1093/nar/gkt840. Epub 2013 Sep 19.

4.

Recombination regulator PRDM9 influences the instability of its own coding sequence in humans.

Jeffreys AJ, Cotton VE, Neumann R, Lam KW.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):600-5. doi: 10.1073/pnas.1220813110. Epub 2012 Dec 24.

5.

A major recombination hotspot in the XqYq pseudoautosomal region gives new insight into processing of human gene conversion events.

Sarbajna S, Denniff M, Jeffreys AJ, Neumann R, Soler Artigas M, Veselis A, May CA.

Hum Mol Genet. 2012 May 1;21(9):2029-38. doi: 10.1093/hmg/dds019. Epub 2012 Jan 30.

PMID:
22291443
6.

Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations.

Berg IL, Neumann R, Sarbajna S, Odenthal-Hesse L, Butler NJ, Jeffreys AJ.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12378-83. doi: 10.1073/pnas.1109531108. Epub 2011 Jul 12.

7.

L1 hybridization enrichment: a method for directly accessing de novo L1 insertions in the human germline.

Freeman P, Macfarlane C, Collier P, Jeffreys AJ, Badge RM.

Hum Mutat. 2011 Aug;32(8):978-88. doi: 10.1002/humu.21533. Epub 2011 Jul 12.

8.

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans.

Berg IL, Neumann R, Lam KW, Sarbajna S, Odenthal-Hesse L, May CA, Jeffreys AJ.

Nat Genet. 2010 Oct;42(10):859-63. doi: 10.1038/ng.658. Epub 2010 Sep 5.

9.

Dynamics and processes of copy number instability in human gamma-globin genes.

Neumann R, Lawson VE, Jeffreys AJ.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8304-9. doi: 10.1073/pnas.1003634107. Epub 2010 Apr 19.

10.

Analysis of meiotic recombination products from human sperm.

Kauppi L, May CA, Jeffreys AJ.

Methods Mol Biol. 2009;557:323-55. doi: 10.1007/978-1-59745-527-5_20. Review.

PMID:
19799191
11.

The rise and fall of a human recombination hot spot.

Jeffreys AJ, Neumann R.

Nat Genet. 2009 May;41(5):625-9. doi: 10.1038/ng.346. Epub 2009 Apr 6.

12.

Minisatellite MS32 alleles show population specificity among Thai, Chinese, and Japanese.

Yuan QH, Tanaka A, Kaszynski RH, Iino M, Okuno T, Tsuruyama T, Yamamoto T, Jeffreys AJ, Tamaki K.

J Mol Evol. 2009 Feb;68(2):126-33. doi: 10.1007/s00239-008-9196-z. Epub 2009 Jan 22.

PMID:
19159965
13.

Processes of de novo duplication of human alpha-globin genes.

Lam KW, Jeffreys AJ.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10950-5. Epub 2007 Jun 15.

14.
15.

Processes of copy-number change in human DNA: the dynamics of {alpha}-globin gene deletion.

Lam KW, Jeffreys AJ.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):8921-7. Epub 2006 May 18.

16.

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.

Neumann R, Jeffreys AJ.

Hum Mol Genet. 2006 May 1;15(9):1401-11. Epub 2006 Mar 16.

PMID:
16543360
17.

Seventh international meeting on single nucleotide polymorphism and complex genome analysis: 'ever bigger scans and an increasingly variable genome'.

Rocha D, Gut I, Jeffreys AJ, Kwok PY, Brookes AJ, Chanock SJ.

Hum Genet. 2006 May;119(4):451-6. Epub 2006 Feb 24.

PMID:
16501918
18.

Allelic recombination and de novo deletions in sperm in the human beta-globin gene region.

Holloway K, Lawson VE, Jeffreys AJ.

Hum Mol Genet. 2006 Apr 1;15(7):1099-111. Epub 2006 Feb 24.

PMID:
16501000
19.

Genetic fingerprinting.

Jeffreys AJ.

Nat Med. 2005 Oct;11(10):1035-9. No abstract available.

PMID:
16211029
20.

Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot.

Jeffreys AJ, Neumann R.

Hum Mol Genet. 2005 Aug 1;14(15):2277-87. Epub 2005 Jun 29.

PMID:
15987698
21.

Human tandem repeat sequences in forensic DNA typing.

Tamaki K, Jeffreys AJ.

Leg Med (Tokyo). 2005 Jul;7(4):244-50. Review.

PMID:
15939656
22.

Activation of the ALT pathway for telomere maintenance can affect other sequences in the human genome.

Jeyapalan JN, Varley H, Foxon JL, Pollock RE, Jeffreys AJ, Henson JD, Reddel RR, Royle NJ.

Hum Mol Genet. 2005 Jul 1;14(13):1785-94. Epub 2005 May 11.

PMID:
15888482
23.
24.

Human recombination hot spots hidden in regions of strong marker association.

Jeffreys AJ, Neumann R, Panayi M, Myers S, Donnelly P.

Nat Genet. 2005 Jun;37(6):601-6. Epub 2005 May 8.

PMID:
15880103
25.

Where the crossovers are: recombination distributions in mammals.

Kauppi L, Jeffreys AJ, Keeney S.

Nat Rev Genet. 2004 Jun;5(6):413-24. Review. No abstract available.

PMID:
15153994
26.

Meiotic recombination hot spots and human DNA diversity.

Jeffreys AJ, Holloway JK, Kauppi L, May CA, Neumann R, Slingsby MT, Webb AJ.

Philos Trans R Soc Lond B Biol Sci. 2004 Jan 29;359(1441):141-52. Review.

27.

Intense and highly localized gene conversion activity in human meiotic crossover hot spots.

Jeffreys AJ, May CA.

Nat Genet. 2004 Feb;36(2):151-6. Epub 2004 Jan 4. Erratum in: Nat Genet. 2004;36(4):427.

PMID:
14704667
29.

Global haplotype diversity in the human insulin gene region.

Stead JD, Hurles ME, Jeffreys AJ.

Genome Res. 2003 Sep;13(9):2101-11.

30.

Two modes of germline instability at human minisatellite MS1 (locus D1S7): complex rearrangements and paradoxical hyperdeletion.

Berg I, Neumann R, Cederberg H, Rannug U, Jeffreys AJ.

Am J Hum Genet. 2003 Jun;72(6):1436-47. Epub 2003 May 12.

31.

High-resolution sperm typing of meiotic recombination in the mouse MHC Ebeta gene.

Yauk CL, Bois PR, Jeffreys AJ.

EMBO J. 2003 Mar 17;22(6):1389-97.

32.

Recombination hotspots rather than population history dominate linkage disequilibrium in the MHC class II region.

Kauppi L, Sajantila A, Jeffreys AJ.

Hum Mol Genet. 2003 Jan 1;12(1):33-40.

PMID:
12490530
33.
34.

Crossover clustering and rapid decay of linkage disequilibrium in the Xp/Yp pseudoautosomal gene SHOX.

May CA, Shone AC, Kalaydjieva L, Sajantila A, Jeffreys AJ.

Nat Genet. 2002 Jul;31(3):272-5. Epub 2002 Jun 24.

PMID:
12089524
35.

Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot.

Jeffreys AJ, Neumann R.

Nat Genet. 2002 Jul;31(3):267-71. Epub 2002 Jun 24.

PMID:
12089523
36.

Minisatellites show rare and simple intra-allelic instability in the mouse germ line.

Bois PR, Grant GR, Jeffreys AJ.

Genomics. 2002 Jul;80(1):2-4.

PMID:
12079275
37.

Allelic structures at hypervariable minisatellite B6.7 in Japanese show population specificity.

Mizukoshi T, Tamaki K, Azumi J, Matsumoto H, Imai K, Jeffreys AJ.

J Hum Genet. 2002;47(5):232-8.

PMID:
12032590
38.

A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus.

Yauk CL, Dubrova YE, Grant GR, Jeffreys AJ.

Mutat Res. 2002 Mar 20;500(1-2):147-56.

PMID:
11890944
39.

Evolutionary fate of an unstable human minisatellite deduced from sperm-mutation spectra of individual alleles.

Buard J, Brenner C, Jeffreys AJ.

Am J Hum Genet. 2002 Apr;70(4):1038-43. Epub 2002 Feb 21.

40.
41.

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex.

Jeffreys AJ, Kauppi L, Neumann R.

Nat Genet. 2001 Oct;29(2):217-22.

PMID:
11586303
42.
43.

The application of minisatellite variant repeat mapping by PCR (MVR-PCR) in a paternity case showing false exclusion due to STR mutation.

Yamamoto T, Tamaki K, Huang XL, Yoshimoto T, Mizutani M, Uchihi R, Katsumata Y, Jeffreys AJ.

J Forensic Sci. 2001 Mar;46(2):374-8.

PMID:
11305445
45.

Amount of elemental calcium in calcium solutions.

Jeffreys AJ.

Anaesthesia. 2001 Feb;56(2):195. No abstract available.

46.

Influence of allele lineage on the role of the insulin minisatellite in susceptibility to type 1 diabetes.

Stead JD, Buard J, Todd JA, Jeffreys AJ.

Hum Mol Genet. 2000 Dec 12;9(20):2929-35.

PMID:
11115836
47.

No correlation between germline mutation at repeat DNA and meiotic crossover in male mice exposed to X-rays or cisplatin.

Barber R, Plumb M, Smith AG, Cesar CE, Boulton E, Jeffreys AJ, Dubrova YE.

Mutat Res. 2000 Dec 20;457(1-2):79-91.

PMID:
11106800
48.

Are DNA profiles breed-specific? A pilot study in pigs.

Signer EN, Dubrova YE, Jeffreys AJ.

Anim Genet. 2000 Aug;31(4):273-6.

PMID:
11086537
49.

Minisatellite mutation frequency in human sperm following radiotherapy.

May CA, Tamaki K, Neumann R, Wilson G, Zagars G, Pollack A, Dubrova YE, Jeffreys AJ, Meistrich ML.

Mutat Res. 2000 Sep 20;453(1):67-75.

PMID:
11006413
50.

Induction of minisatellite mutations in the mouse germline by low-dose chronic exposure to gamma-radiation and fission neutrons.

Dubrova YE, Plumb M, Brown J, Boulton E, Goodhead D, Jeffreys AJ.

Mutat Res. 2000 Sep 20;453(1):17-24.

PMID:
11006408

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