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Items: 1 to 50 of 63

1.

MicroRNA-125b Regulates Fibroblast Apoptosis Proliferation in Systemic Sclerosis.

Kozlova A, Pachera E, Maurer B, Jüngel A, Distler JHW, Kania G, Distler O.

Arthritis Rheumatol. 2019 Jul 16. doi: 10.1002/art.41041. [Epub ahead of print]

PMID:
31309742
2.

OTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis.

Takata M, Pachera E, Frank-Bertoncelj M, Kozlova A, Jüngel A, Whitfield ML, Assassi S, Calcagni M, de Vries-Bouwstra J, Huizinga TW, Kurreeman F, Kania G, Distler O.

Front Immunol. 2019 May 17;10:1100. doi: 10.3389/fimmu.2019.01100. eCollection 2019.

3.

Finite-volume scheme for a degenerate cross-diffusion model motivated from ion transport.

Cancès C, Chainais-Hillairet C, Gerstenmayer A, Jüngel A.

Numer Methods Partial Differ Equ. 2019 Mar;35(2):545-575. doi: 10.1002/num.22313. Epub 2018 Aug 20.

4.

PU.1 controls fibroblast polarization and tissue fibrosis.

Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A.

Nature. 2019 Feb;566(7744):344-349. doi: 10.1038/s41586-019-0896-x. Epub 2019 Jan 30.

PMID:
30700907
5.

Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models.

Randall MJ, Jüngel A, Rimann M, Wuertz-Kozak K.

Front Bioeng Biotechnol. 2018 Oct 31;6:154. doi: 10.3389/fbioe.2018.00154. eCollection 2018. Review.

6.

Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway.

Iwamoto N, Fukui S, Takatani A, Shimizu T, Umeda M, Nishino A, Igawa T, Koga T, Kawashiri SY, Ichinose K, Tmai M, Nakamura H, Origuchi T, Chiba K, Osaki M, Jüngel A, Gay S, Kawakami A.

Arthritis Res Ther. 2018 Aug 29;20(1):189. doi: 10.1186/s13075-018-1703-z.

7.

TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles.

Frank-Bertoncelj M, Pisetsky DS, Kolling C, Michel BA, Gay RE, Jüngel A, Gay S.

Front Immunol. 2018 Jan 29;9:28. doi: 10.3389/fimmu.2018.00028. eCollection 2018.

8.

Association between circulating miRNAs and spinal involvement in patients with axial spondyloarthritis.

Prajzlerová K, Grobelná K, Hušáková M, Forejtová Š, Jüngel A, Gay S, Vencovský J, Pavelka K, Šenolt L, Filková M.

PLoS One. 2017 Sep 22;12(9):e0185323. doi: 10.1371/journal.pone.0185323. eCollection 2017.

9.

Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis.

Pleštilová L, Neidhart M, Russo G, Frank-Bertoncelj M, Ospelt C, Ciurea A, Kolling C, Gay RE, Michel BA, Vencovský J, Gay S, Jüngel A.

PLoS One. 2016 Nov 28;11(11):e0166920. doi: 10.1371/journal.pone.0166920. eCollection 2016.

10.

MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts.

Gaur N, Karouzakis E, Glück S, Bagdonas E, Jüngel A, Michel BA, Gay RE, Gay S, Frank-Bertoncelj M, Neidhart M.

RMD Open. 2016 Oct 14;2(2):e000299. eCollection 2016.

11.

A review of recent advances in the spherical harmonics expansion method for semiconductor device simulation.

Rupp K, Jungemann C, Hong SM, Bina M, Grasser T, Jüngel A.

J Comput Electron. 2016;15:939-958. Epub 2016 May 11. Review.

12.

Protein tyrosine phosphatase nonreceptor type 2: an important regulator of lnterleukin-6 production in rheumatoid arthritis synovial fibroblasts.

Aradi B, Kato M, Filkova M, Karouzakis E, Klein K, Scharl M, Kolling C, Michel BA, Gay RE, Buzas EI, Gay S, Jüngel A.

Arthritis Rheumatol. 2015 Oct;67(10):2624-33. doi: 10.1002/art.39256.

13.

Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression.

Iwamoto N, Vettori S, Maurer B, Brock M, Pachera E, Jüngel A, Calcagni M, Gay RE, Whitfield ML, Distler JH, Gay S, Distler O.

Ann Rheum Dis. 2016 Jan;75(1):303-10. doi: 10.1136/annrheumdis-2014-205326. Epub 2014 Nov 10.

PMID:
25384965
14.

Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis.

Svegliati S, Marrone G, Pezone A, Spadoni T, Grieco A, Moroncini G, Grieco D, Vinciguerra M, Agnese S, Jüngel A, Distler O, Musti AM, Gabrielli A, Avvedimento EV.

Sci Signal. 2014 Sep 2;7(341):ra84. doi: 10.1126/scisignal.2004592.

PMID:
25185156
15.

[Epigenetic modifications in autoimmune diseases].

Ramming A, Distler JH, Schett G, Gay S, Jüngel A.

Z Rheumatol. 2014 Sep;73(7):636-8. doi: 10.1007/s00393-014-1388-x. German. No abstract available.

PMID:
25135041
16.

Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis.

Neidhart M, Karouzakis E, Jüngel A, Gay RE, Gay S.

Arthritis Rheumatol. 2014 Jul;66(7):1723-33. doi: 10.1002/art.38574.

17.

Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells.

Schuberth PC, Hagedorn C, Jensen SM, Gulati P, van den Broek M, Mischo A, Soltermann A, Jüngel A, Marroquin Belaunzaran O, Stahel R, Renner C, Petrausch U.

J Transl Med. 2013 Aug 12;11:187. doi: 10.1186/1479-5876-11-187.

18.

Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis.

Filková M, Aradi B, Senolt L, Ospelt C, Vettori S, Mann H, Filer A, Raza K, Buckley CD, Snow M, Vencovský J, Pavelka K, Michel BA, Gay RE, Gay S, Jüngel A.

Ann Rheum Dis. 2014 Oct;73(10):1898-904. doi: 10.1136/annrheumdis-2012-202815. Epub 2013 Jul 29.

19.

MicroRNAs in rheumatoid arthritis: potential role in diagnosis and therapy.

Filková M, Jüngel A, Gay RE, Gay S.

BioDrugs. 2012 Jun 1;26(3):131-41. doi: 10.2165/11631480-000000000-00000. Review.

PMID:
22494429
20.

Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.

Kesel N, Köhler D, Herich L, Laudien M, Holl-Ulrich K, Jüngel A, Neidhart M, Gay S, Gay RE, Csernok E, Lamprecht P, Gross WL, Schumacher U, Ullrich S.

Am J Pathol. 2012 May;180(5):2144-55. doi: 10.1016/j.ajpath.2012.01.021. Epub 2012 Mar 23.

PMID:
22449947
21.

Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance.

Niederer F, Trenkmann M, Ospelt C, Karouzakis E, Neidhart M, Stanczyk J, Kolling C, Gay RE, Detmar M, Gay S, Jüngel A, Kyburz D.

Arthritis Rheum. 2012 Jun;64(6):1771-9. doi: 10.1002/art.34334. Epub 2011 Dec 12.

22.

Epigenetic modifications: novel therapeutic strategies for systemic sclerosis?

Jüngel A, Distler JH, Gay S, Distler O.

Expert Rev Clin Immunol. 2011 Jul;7(4):475-80. doi: 10.1586/eci.11.37. Review.

PMID:
21790290
23.

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts.

Karouzakis E, Rengel Y, Jüngel A, Kolling C, Gay RE, Michel BA, Tak PP, Gay S, Neidhart M, Ospelt C.

Genes Immun. 2011 Dec;12(8):643-52. doi: 10.1038/gene.2011.45. Epub 2011 Jul 14.

24.

Animal models for arthritis: innovative tools for prevention and treatment.

Kollias G, Papadaki P, Apparailly F, Vervoordeldonk MJ, Holmdahl R, Baumans V, Desaintes C, Di Santo J, Distler J, Garside P, Hegen M, Huizinga TW, Jüngel A, Klareskog L, McInnes I, Ragoussis I, Schett G, Hart B', Tak PP, Toes R, van den Berg W, Wurst W, Gay S.

Ann Rheum Dis. 2011 Aug;70(8):1357-62. doi: 10.1136/ard.2010.148551. Epub 2011 May 30. Review.

25.

Platelet-derived serotonin links vascular disease and tissue fibrosis.

Dees C, Akhmetshina A, Zerr P, Reich N, Palumbo K, Horn A, Jüngel A, Beyer C, Krönke G, Zwerina J, Reiter R, Alenina N, Maroteaux L, Gay S, Schett G, Distler O, Distler JH.

J Exp Med. 2011 May 9;208(5):961-72. doi: 10.1084/jem.20101629. Epub 2011 Apr 25.

26.

Induction of apoptosis in circulating angiogenic cells by microparticles.

Distler JH, Akhmetshina A, Dees C, Jüngel A, Stürzl M, Gay S, Pisetsky DS, Schett G, Distler O.

Arthritis Rheum. 2011 Jul;63(7):2067-77. doi: 10.1002/art.30361.

27.

[Epigentics in rheumatic diseases].

Jüngel A, Gay S.

Z Rheumatol. 2011 Apr;70(3):205-8, 210-2. doi: 10.1007/s00393-010-0689-y. German.

28.

[miRNA in epigenetics of rheumatic diseases].

Jüngel A, Gay S.

Praxis (Bern 1994). 2011 Jan 5;100(1):37-43. doi: 10.1024/1661-8157/a00404. Review. German.

29.

What can we learn from epigenetics in the year 2009?

Jüngel A, Ospelt C, Gay S.

Curr Opin Rheumatol. 2010 May;22(3):284-92. doi: 10.1097/BOR.0b013e3283389641. Review.

30.

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis.

Maurer B, Stanczyk J, Jüngel A, Akhmetshina A, Trenkmann M, Brock M, Kowal-Bielecka O, Gay RE, Michel BA, Distler JH, Gay S, Distler O.

Arthritis Rheum. 2010 Jun;62(6):1733-43. doi: 10.1002/art.27443.

31.

Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.

Ospelt C, Mertens JC, Jüngel A, Brentano F, Maciejewska-Rodriguez H, Huber LC, Hemmatazad H, Wüest T, Knuth A, Gay RE, Michel BA, Gay S, Renner C, Bauer S.

Arthritis Rheum. 2010 May;62(5):1224-35. doi: 10.1002/art.27395.

32.

Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression.

Maciejewska-Rodrigues H, Karouzakis E, Strietholt S, Hemmatazad H, Neidhart M, Ospelt C, Gay RE, Michel BA, Pap T, Gay S, Jüngel A.

J Autoimmun. 2010 Aug;35(1):15-22. doi: 10.1016/j.jaut.2009.12.010. Epub 2010 Jan 15.

33.

Functional autoantibodies against serpin E2 in rheumatoid arthritis.

Maciejewska-Rodrigues H, Al-Shamisi M, Hemmatazad H, Ospelt C, Bouton MC, Jäger D, Cope AP, Charles P, Plant D, Distler JH, Gay RE, Michel BA, Knuth A, Neidhart M, Gay S, Jüngel A.

Arthritis Rheum. 2010 Jan;62(1):93-104. doi: 10.1002/art.25038.

34.

Inhibitor of DNA binding/differentiation 2 induced by hypoxia promotes synovial fibroblast-dependent osteoclastogenesis.

Kurowska-Stolarska M, Distler JH, Jüngel A, Rudnicka W, Neumann E, Pap T, Wenger RH, Michel BA, Müller-Ladner U, Gay RE, Maslinski W, Gay S, Distler O.

Arthritis Rheum. 2009 Dec;60(12):3663-75. doi: 10.1002/art.25001.

35.

Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis.

Maurer B, Busch N, Jüngel A, Pileckyte M, Gay RE, Michel BA, Schett G, Gay S, Distler J, Distler O.

Circulation. 2009 Dec 8;120(23):2367-76. doi: 10.1161/CIRCULATIONAHA.109.855114. Epub 2009 Nov 23.

36.

Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity.

Sellam J, Proulle V, Jüngel A, Ittah M, Miceli Richard C, Gottenberg JE, Toti F, Benessiano J, Gay S, Freyssinet JM, Mariette X.

Arthritis Res Ther. 2009;11(5):R156. doi: 10.1186/ar2833. Epub 2009 Oct 15.

37.

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.

Jüngel A, Ospelt C, Lesch M, Thiel M, Sunyer T, Schorr O, Michel BA, Gay RE, Kolling C, Flory C, Gay S, Neidhart M.

Ann Rheum Dis. 2010 May;69(5):898-902. doi: 10.1136/ard.2008.106021. Epub 2009 Jun 3.

38.

Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis.

Hemmatazad H, Rodrigues HM, Maurer B, Brentano F, Pileckyte M, Distler JH, Gay RE, Michel BA, Gay S, Huber LC, Distler O, Jüngel A.

Arthritis Rheum. 2009 May;60(5):1519-29. doi: 10.1002/art.24494.

39.

Innate immunity, epigenetics and autoimmunity in rheumatoid arthritis.

Maciejewska Rodrigues H, Jüngel A, Gay RE, Gay S.

Mol Immunol. 2009 Nov;47(1):12-8. doi: 10.1016/j.molimm.2009.01.010. Epub 2009 Feb 15.

PMID:
19232437
40.

Expression, regulation, and signaling of the pattern-recognition receptor nucleotide-binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts.

Ospelt C, Brentano F, Jüngel A, Rengel Y, Kolling C, Michel BA, Gay RE, Gay S.

Arthritis Rheum. 2009 Feb;60(2):355-63. doi: 10.1002/art.24226.

41.

Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo.

Venalis P, Maurer B, Akhmetshina A, Busch N, Dees C, Stürzl M, Zwerina J, Jüngel A, Gay S, Schett G, Distler O, Distler JH.

J Cell Mol Med. 2009 Oct;13(10):4185-91. doi: 10.1111/j.1582-4934.2008.00492.x.

42.

The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis.

Guiducci S, Distler JH, Jüngel A, Huscher D, Huber LC, Michel BA, Gay RE, Pisetsky DS, Gay S, Matucci-Cerinic M, Distler O.

Arthritis Rheum. 2008 Sep;58(9):2845-53. doi: 10.1002/art.23735.

43.

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis.

Akhmetshina A, Dees C, Pileckyte M, Maurer B, Axmann R, Jüngel A, Zwerina J, Gay S, Schett G, Distler O, Distler JH.

FASEB J. 2008 Jul;22(7):2214-22. doi: 10.1096/fj.07-105627. Epub 2008 Mar 7.

PMID:
18326784
44.

Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis.

Distler JH, Jüngel A, Pileckyte M, Zwerina J, Michel BA, Gay RE, Kowal-Bielecka O, Matucci-Cerinic M, Schett G, Marti HH, Gay S, Distler O.

Arthritis Rheum. 2007 Dec;56(12):4203-15.

45.

Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.

Jüngel A, Distler O, Schulze-Horsel U, Huber LC, Ha HR, Simmen B, Kalden JR, Pisetsky DS, Gay S, Distler JH.

Arthritis Rheum. 2007 Nov;56(11):3564-74.

46.

Epigenetics in inflammatory rheumatic diseases.

Huber LC, Stanczyk J, Jüngel A, Gay S.

Arthritis Rheum. 2007 Nov;56(11):3523-31. Review. No abstract available.

47.

Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis.

Huber LC, Distler JH, Moritz F, Hemmatazad H, Hauser T, Michel BA, Gay RE, Matucci-Cerinic M, Gay S, Distler O, Jüngel A.

Arthritis Rheum. 2007 Aug;56(8):2755-64.

48.

Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients.

Huber LC, Brock M, Hemmatazad H, Giger OT, Moritz F, Trenkmann M, Distler JH, Gay RE, Kolling C, Moch H, Michel BA, Gay S, Distler O, Jüngel A.

Arthritis Rheum. 2007 Apr;56(4):1087-93.

49.

Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.

Distler JH, Jüngel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S, Distler O.

Arthritis Rheum. 2007 Jan;56(1):311-22.

50.

The role of membrane lipids in the induction of macrophage apoptosis by microparticles.

Huber LC, Jüngel A, Distler JH, Moritz F, Gay RE, Michel BA, Pisetsky DS, Gay S, Distler O.

Apoptosis. 2007 Feb;12(2):363-74.

PMID:
17191114

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