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Best matches for Jørgensen TN[au]:

Androgen-Induced Immunosuppression. Gubbels Bupp MR et al. Front Immunol. (2018)

Suppressive effects of androgens on the immune system. Trigunaite A et al. Cell Immunol. (2015)

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Zhang CJ et al. Nat Commun. (2018)

Search results

Items: 47

1.

Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice.

Davison LM, Liu JC, Huang L, Carroll TM, Mellor AL, Jørgensen TN.

Front Immunol. 2019 Aug 27;10:2017. doi: 10.3389/fimmu.2019.02017. eCollection 2019.

2.

Immunological effects of vitamin D and their relations to autoimmunity.

Yamamoto E, Jørgensen TN.

J Autoimmun. 2019 Jun;100:7-16. doi: 10.1016/j.jaut.2019.03.002. Epub 2019 Mar 8. Review.

PMID:
30853311
3.

Chronic myeloid leukemia: Two mysteries.

Radivoyevitch T, Jorgensen TN, Lindner DJ, Maciejewski JP, Miyazaki Y, Gale RP.

Leuk Res. 2019 Apr;79:3-5. doi: 10.1016/j.leukres.2019.02.003. Epub 2019 Feb 12. No abstract available.

PMID:
30780032
4.

Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?

Forsingdal A, Jørgensen TN, Olsen L, Werge T, Didriksen M, Nielsen J.

Biol Psychiatry. 2019 Jan 1;85(1):13-24. doi: 10.1016/j.biopsych.2018.07.004. Epub 2018 Jul 12. Review.

PMID:
30144930
5.

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.

Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X.

Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3.

6.

Androgen-Induced Immunosuppression.

Gubbels Bupp MR, Jorgensen TN.

Front Immunol. 2018 Apr 17;9:794. doi: 10.3389/fimmu.2018.00794. eCollection 2018. Review.

7.

New Treatments for Systemic Lupus Erythematosus on the Horizon: Targeting Plasmacytoid Dendritic Cells to Inhibit Cytokine Production.

Davison LM, Jorgensen TN.

J Clin Cell Immunol. 2017;8(6). pii: 534. doi: 10.4172/2155-9899.1000534. Epub 2017 Dec 20.

8.

Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains.

Rahbek-Clemmensen T, Lycas MD, Erlendsson S, Eriksen J, Apuschkin M, Vilhardt F, Jørgensen TN, Hansen FH, Gether U.

Nat Commun. 2017 Sep 29;8(1):740. doi: 10.1038/s41467-017-00790-3.

9.

A kinome wide screen identifies novel kinases involved in regulation of monoamine transporter function.

Vuorenpää A, Ammendrup-Johnsen I, Jørgensen TN, Gether U.

Neurochem Int. 2016 Sep;98:103-14. doi: 10.1016/j.neuint.2016.03.013. Epub 2016 Mar 26.

PMID:
27020406
10.

Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini.

Vuorenpää A, Jørgensen TN, Newman AH, Madsen KL, Scheinin M, Gether U.

J Biol Chem. 2016 Mar 11;291(11):5634-51. doi: 10.1074/jbc.M115.702050. Epub 2016 Jan 19.

11.

Suppressive effects of androgens on the immune system.

Trigunaite A, Dimo J, Jørgensen TN.

Cell Immunol. 2015 Apr;294(2):87-94. doi: 10.1016/j.cellimm.2015.02.004. Epub 2015 Feb 14. Review.

PMID:
25708485
12.

Sex disparities in the immune response.

Jørgensen TN.

Cell Immunol. 2015 Apr;294(2):61-2. doi: 10.1016/j.cellimm.2015.02.001. Epub 2015 Feb 4. No abstract available.

PMID:
25670393
13.
14.

The serotonin transporter undergoes constitutive internalization and is primarily sorted to late endosomes and lysosomal degradation.

Rahbek-Clemmensen T, Bay T, Eriksen J, Gether U, Jørgensen TN.

J Biol Chem. 2014 Aug 15;289(33):23004-19. doi: 10.1074/jbc.M113.495754. Epub 2014 Jun 27.

15.

Novel and high affinity fluorescent ligands for the serotonin transporter based on (s)-citalopram.

Kumar V, Rahbek-Clemmensen T, Billesbølle CB, Jorgensen TN, Gether U, Newman AH.

ACS Med Chem Lett. 2014 Mar 27;5(6):696-9. doi: 10.1021/ml5000806. eCollection 2014 Jun 12.

16.

Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice.

David A, Trigunaite A, Macleod MK, Johnson AC, Marrack P, Jørgensen TN.

Genes Immun. 2014 Apr-May;15(3):153-61. doi: 10.1038/gene.2014.2. Epub 2014 Jan 30.

17.

Serotonin-induced down-regulation of cell surface serotonin transporter.

Jørgensen TN, Christensen PM, Gether U.

Neurochem Int. 2014 Jul;73:107-12. doi: 10.1016/j.neuint.2014.01.005. Epub 2014 Jan 22.

18.

Gr1+ cells suppress T-dependent antibody responses in (NZB x NZW)F1 male mice through inhibition of T follicular helper cells and germinal center formation.

Der E, Dimo J, Trigunaite A, Jones J, Jørgensen TN.

J Immunol. 2014 Feb 15;192(4):1570-6. doi: 10.4049/jimmunol.1302479. Epub 2014 Jan 17.

19.

Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice.

Giltiay NV, Lu Y, Cullen JL, Jørgensen TN, Shlomchik MJ, Li X.

J Immunol. 2013 Sep 1;191(5):2155-63. doi: 10.4049/jimmunol.1300152. Epub 2013 Jul 31.

20.

Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

Rickhag M, Owens WA, Winkler MT, Strandfelt KN, Rathje M, Sørensen G, Andresen B, Madsen KL, Jørgensen TN, Wörtwein G, Woldbye DP, Sitte H, Daws LC, Gether U.

J Biol Chem. 2013 Sep 20;288(38):27534-44. doi: 10.1074/jbc.M112.441295. Epub 2013 Jul 24.

21.

Intracellular and circulating neuronal antinuclear antibodies in human epilepsy.

Iffland PH 2nd, Carvalho-Tavares J, Trigunaite A, Man S, Rasmussen P, Alexopoulos A, Ghosh C, Jørgensen TN, Janigro D.

Neurobiol Dis. 2013 Nov;59:206-19. doi: 10.1016/j.nbd.2013.07.006. Epub 2013 Jul 21.

22.

Gr-1(high) CD11b+ cells suppress B cell differentiation and lupus-like disease in lupus-prone male mice.

Trigunaite A, Khan A, Der E, Song A, Varikuti S, Jørgensen TN.

Arthritis Rheum. 2013 Sep;65(9):2392-402. doi: 10.1002/art.38048.

23.

A rhodamine-labeled citalopram analogue as a high-affinity fluorescent probe for the serotonin transporter.

Zhang P, Jørgensen TN, Loland CJ, Newman AH.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):323-6. doi: 10.1016/j.bmcl.2012.10.089. Epub 2012 Nov 1.

24.

Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease.

Johnson AC, Davison LM, Giltiay NV, Vareechon C, Li X, Jørgensen TN.

Eur J Immunol. 2012 Jul;42(7):1695-705. doi: 10.1002/eji.201142238.

25.

Brain-derived neurotrophic factor (BDNF) enhances GABA transport by modulating the trafficking of GABA transporter-1 (GAT-1) from the plasma membrane of rat cortical astrocytes.

Vaz SH, Jørgensen TN, Cristóvão-Ferreira S, Duflot S, Ribeiro JA, Gether U, Sebastião AM.

J Biol Chem. 2011 Nov 25;286(47):40464-76. doi: 10.1074/jbc.M111.232009. Epub 2011 Oct 3.

26.

SLC6 neurotransmitter transporters: structure, function, and regulation.

Kristensen AS, Andersen J, Jørgensen TN, Sørensen L, Eriksen J, Loland CJ, Strømgaard K, Gether U.

Pharmacol Rev. 2011 Sep;63(3):585-640. doi: 10.1124/pr.108.000869. Epub 2011 Jul 13. Review.

PMID:
21752877
27.

Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons.

Eriksen J, Bjørn-Yoshimoto WE, Jørgensen TN, Newman AH, Gether U.

J Biol Chem. 2010 Aug 27;285(35):27289-301. doi: 10.1074/jbc.M110.131003. Epub 2010 Jun 15.

28.

The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation.

Giltiay NV, Lu Y, Allman D, Jørgensen TN, Li X.

J Immunol. 2010 Jul 1;185(1):99-109. doi: 10.4049/jimmunol.0903312. Epub 2010 Jun 11.

29.

The N terminus of monoamine transporters is a lever required for the action of amphetamines.

Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH.

J Biol Chem. 2010 Apr 2;285(14):10924-38. doi: 10.1074/jbc.M109.083154. Epub 2010 Jan 29.

30.

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges.

Eriksen J, Jørgensen TN, Gether U.

J Neurochem. 2010 Apr;113(1):27-41. doi: 10.1111/j.1471-4159.2010.06599.x. Epub 2010 Jan 18. Review.

31.

Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.

Jørgensen TN, Alfaro J, Enriquez HL, Jiang C, Loo WM, Atencio S, Bupp MR, Mailloux CM, Metzger T, Flannery S, Rozzo SJ, Kotzin BL, Rosemblatt M, Bono MR, Erickson LD.

J Immunol. 2010 Jan 15;184(2):775-86. doi: 10.4049/jimmunol.0901322. Epub 2009 Dec 16.

32.

Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritis.

Baudino L, Yoshinobu K, Morito N, Kikuchi S, Fossati-Jimack L, Morley BJ, Vyse TJ, Hirose S, Jørgensen TN, Tucker RM, Roark CL, Kotzin BL, Evans LH, Izui S.

J Immunol. 2008 Aug 15;181(4):2846-54.

33.

Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome.

Qian Y, Giltiay N, Xiao J, Wang Y, Tian J, Han S, Scott M, Carter R, Jorgensen TN, Li X.

Eur J Immunol. 2008 Aug;38(8):2219-28. doi: 10.1002/eji.200738113.

34.

Identification of candidate genes that influence sex hormone-dependent disease phenotypes in mouse lupus.

Gubbels Bupp MR, Jørgensen TN, Kotzin BL.

Genes Immun. 2008 Jan;9(1):47-56. Epub 2007 Nov 29.

PMID:
18046341
35.

Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice.

Jørgensen TN, Roper E, Thurman JM, Marrack P, Kotzin BL.

Genes Immun. 2007 Dec;8(8):653-62. Epub 2007 Sep 20.

PMID:
17882225
36.

Bim and Bcl-2 mutually affect the expression of the other in T cells.

Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P.

J Immunol. 2007 Sep 15;179(6):3417-24.

37.

Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice.

Jørgensen TN, Thurman J, Izui S, Falta MT, Metzger TE, Flannery SA, Kappler J, Marrack P, Kotzin BL.

Genes Immun. 2006 Oct;7(7):555-67. Epub 2006 Aug 10.

PMID:
16900204
38.

Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis.

Xin H, D'Souza S, Jørgensen TN, Vaughan AT, Lengyel P, Kotzin BL, Choubey D.

J Immunol. 2006 May 15;176(10):5863-70.

39.

Effects of MHC and gender on lupus-like autoimmunity in Nba2 congenic mice.

Gubbels MR, Jørgensen TN, Metzger TE, Menze K, Steele H, Flannery SA, Rozzo SJ, Kotzin BL.

J Immunol. 2005 Nov 1;175(9):6190-6.

40.

BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus.

Stohl W, Xu D, Kim KS, Koss MN, Jorgensen TN, Deocharan B, Metzger TE, Bixler SA, Hong YS, Ambrose CM, Mackay F, Morel L, Putterman C, Kotzin BL, Kalled SL.

Arthritis Rheum. 2005 Jul;52(7):2080-91.

41.

New insights into disease pathogenesis from mouse lupus genetics.

Jørgensen TN, Gubbels MR, Kotzin BL.

Curr Opin Immunol. 2004 Dec;16(6):787-93. Review.

PMID:
15511674
42.

CD40 is necessary for activation of naïve T cells by a dendritic cell line in vivo but not in vitro.

Haase C, Michelsen BK, Jørgensen TN.

Scand J Immunol. 2004 Mar;59(3):237-45.

43.

Links between type I interferons and the genetic basis of disease in mouse lupus.

Jørgensen TN, Gubbels MR, Kotzin BL.

Autoimmunity. 2003 Dec;36(8):491-502. Review.

PMID:
14984026
44.

Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility.

Pramanik R, Jørgensen TN, Xin H, Kotzin BL, Choubey D.

J Biol Chem. 2004 Apr 16;279(16):16121-7. Epub 2004 Feb 5.

45.

Low expression of insulin in the thymus of non-obese diabetic mice.

Brimnes MK, Jensen T, Jørgensen TN, Michelsen BK, Troelsen J, Werdelin O.

J Autoimmun. 2002 Dec;19(4):203-13.

PMID:
12473241
47.

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