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Best matches for Jänicke RU[au]:

Emerging roles of caspase-3 in apoptosis. Porter AG et al. Cell Death Differ. (1999)

Mechanisms of skin aging induced by EGFR inhibitors. Gerber PA et al. Support Care Cancer. (2016)

The DEAD-box RNA helicase DDX41 is a novel repressor of p21<sup>WAF1/CIP1</sup> mRNA translation. Peters D et al. J Biol Chem. (2017)

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Items: 1 to 50 of 58


The RNA-binding protein RBM47 is a novel regulator of cell fate decisions by transcriptionally controlling the p53-p21-axis.

Radine C, Peters D, Reese A, Neuwahl J, Budach W, Jänicke RU, Sohn D.

Cell Death Differ. 2019 Sep 11. doi: 10.1038/s41418-019-0414-6. [Epub ahead of print]


The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells.

Ingenhag D, Reister S, Auer F, Bhatia S, Wildenhain S, Picard D, Remke M, Hoell JI, Kloetgen A, Sohn D, Jänicke RU, Koegler G, Borkhardt A, Hauer J.

Haematologica. 2019 Jan;104(1):35-46. doi: 10.3324/haematol.2018.189407. Epub 2018 Aug 9.


The DEAD-box RNA helicase DDX41 is a novel repressor of p21WAF1/CIP1 mRNA translation.

Peters D, Radine C, Reese A, Budach W, Sohn D, Jänicke RU.

J Biol Chem. 2017 May 19;292(20):8331-8341. doi: 10.1074/jbc.M116.772327. Epub 2017 Mar 27.


Simulated Space Radiation: Impact of Four Different Types of High-Dose Ionizing Radiation on the Lichen Xanthoria elegans.

Brandt A, Meeßen J, Jänicke RU, Raguse M, Ott S.

Astrobiology. 2017 Feb;17(2):136-144. doi: 10.1089/ast.2015.1455.


Mechanisms of skin aging induced by EGFR inhibitors.

Gerber PA, Buhren BA, Schrumpf H, Hevezi P, Bölke E, Sohn D, Jänicke RU, Belum VR, Robert C, Lacouture ME, Homey B.

Support Care Cancer. 2016 Oct;24(10):4241-8. doi: 10.1007/s00520-016-3254-7. Epub 2016 May 10.


miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3.

Sohn D, Peters D, Piekorz RP, Budach W, Jänicke RU.

Oncotarget. 2016 Mar 29;7(13):15915-29. doi: 10.18632/oncotarget.7432.


The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.

Neise D, Sohn D, Stefanski A, Goto H, Inagaki M, Wesselborg S, Budach W, Stühler K, Jänicke RU.

Cell Death Dis. 2013 Oct 17;4:e859. doi: 10.1038/cddis.2013.386.


p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.

Milojkovic A, Hemmati PG, Müer A, Overkamp T, Chumduri C, Jänicke RU, Gillissen B, Daniel PT.

Int J Cancer. 2013 Dec 1;133(11):2551-62. doi: 10.1002/ijc.28279. Epub 2013 Aug 1.


Oppositional regulation of Noxa by JNK1 and JNK2 during apoptosis induced by proteasomal inhibitors.

Pietkiewicz S, Sohn D, Piekorz RP, Grether-Beck S, Budach W, Sabapathy K, Jänicke RU.

PLoS One. 2013 Apr 11;8(4):e61438. doi: 10.1371/journal.pone.0061438. Print 2013.


XRCC4 controls nuclear import and distribution of Ligase IV and exchanges faster at damaged DNA in complex with Ligase IV.

Berg E, Christensen MO, Dalla Rosa I, Wannagat E, Jänicke RU, Rösner LM, Dirks WG, Boege F, Mielke C.

DNA Repair (Amst). 2011 Dec 10;10(12):1232-42. doi: 10.1016/j.dnarep.2011.09.012. Epub 2011 Oct 5.


Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway.

Zhang Y, Johansson E, Miller ML, Jänicke RU, Ferguson DJ, Plas D, Meller J, Anderson MW.

PLoS One. 2011;6(9):e25284. doi: 10.1371/journal.pone.0025284. Epub 2011 Sep 30.


Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1).

Sohn D, Budach W, Jänicke RU.

Cell Death Differ. 2011 Oct;18(10):1664-74. doi: 10.1038/cdd.2011.34. Epub 2011 Apr 8.


Caspase-3-dependent mitotic checkpoint inactivation by the small-molecule inducers of mitotic slippage SU6656 and geraldol.

Riffell JL, Jänicke RU, Roberge M.

Mol Cancer Ther. 2011 May;10(5):839-49. doi: 10.1158/1535-7163.MCT-10-0909. Epub 2011 Mar 25.


The centrosome and mitotic spindle apparatus in cancer and senescence.

Schmidt S, Essmann F, Cirstea IC, Kuck F, Thakur HC, Singh M, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

Cell Cycle. 2010 Nov 15;9(22):4469-73.


Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAF1/CIP1.

Neise D, Sohn D, Budach W, Jänicke RU.

Cell Cycle. 2010 Sep 1;9(17):3575-83. Epub 2010 Sep 25.


The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program.

Schmidt S, Schneider L, Essmann F, Cirstea IC, Kuck F, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP.

Oncogene. 2010 Nov 18;29(46):6184-92. doi: 10.1038/onc.2010.354. Epub 2010 Aug 23.


The do's and don'ts of p53 isoforms.

Jänicke RU, Graupner V, Budach W, Essmann F.

Biol Chem. 2009 Oct;390(10):951-63. doi: 10.1515/BC.2009.093. Review.


Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin-cAMP pathway.

Twarock S, Röck K, Sarbia M, Weber AA, Jänicke RU, Fischer JW.

Br J Pharmacol. 2009 May;157(2):234-43. doi: 10.1111/j.1476-5381.2009.00138.x. Epub 2009 Mar 26.


Functional characterization of p53beta and p53gamma, two isoforms of the tumor suppressor p53.

Graupner V, Schulze-Osthoff K, Essmann F, Jänicke RU.

Cell Cycle. 2009 Apr 15;8(8):1238-48. Epub 2009 Apr 23.


Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.

Sohn D, Graupner V, Neise D, Essmann F, Schulze-Osthoff K, Jänicke RU.

Cell Death Differ. 2009 Jun;16(6):869-78. doi: 10.1038/cdd.2009.17. Epub 2009 Feb 20.


MCF-7 breast carcinoma cells do not express caspase-3.

Jänicke RU.

Breast Cancer Res Treat. 2009 Sep;117(1):219-21. doi: 10.1007/s10549-008-0217-9. Epub 2008 Oct 14. No abstract available.


The dark side of a tumor suppressor: anti-apoptotic p53.

Jänicke RU, Sohn D, Schulze-Osthoff K.

Cell Death Differ. 2008 Jun;15(6):959-76. doi: 10.1038/cdd.2008.33. Epub 2008 Mar 21. Review.


Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.

Neise D, Graupner V, Gillissen BF, Daniel PT, Schulze-Osthoff K, Jänicke RU, Essmann F.

Oncogene. 2008 Feb 28;27(10):1387-96. Epub 2007 Sep 3.


Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment.

Janssen K, Pohlmann S, Jänicke RU, Schulze-Osthoff K, Fischer U.

Blood. 2007 Nov 15;110(10):3662-72. Epub 2007 Jul 25.


The multiple battles fought by anti-apoptotic p21.

Jänicke RU, Sohn D, Essmann F, Schulze-Osthoff K.

Cell Cycle. 2007 Feb 15;6(4):407-13. Epub 2007 Feb 19.


Caspase-10 in mouse or not?

Jänicke RU, Sohn D, Totzke G, Schulze-Osthoff K.

Science. 2006 Jun 30;312(5782):1874. No abstract available.


Cell death, caspase activation, and HMGB1 release of porcine choroid plexus epithelial cells during Streptococcus suis infection in vitro.

Tenenbaum T, Essmann F, Adam R, Seibt A, Jänicke RU, Novotny GE, Galla HJ, Schroten H.

Brain Res. 2006 Jul 19;1100(1):1-12. Epub 2006 Jun 15.


Friend or foe? The proteasome in combined cancer therapy.

Sohn D, Totzke G, Schulze-Osthoff K, Jänicke RU.

Cell Cycle. 2006 Apr;5(8):841-5. Epub 2006 Apr 17. Review.


A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.

Totzke G, Essmann F, Pohlmann S, Lindenblatt C, Jänicke RU, Schulze-Osthoff K.

J Biol Chem. 2006 May 5;281(18):12645-54. Epub 2006 Mar 2.


The proteasome is required for rapid initiation of death receptor-induced apoptosis.

Sohn D, Totzke G, Essmann F, Schulze-Osthoff K, Levkau B, Jänicke RU.

Mol Cell Biol. 2006 Mar;26(5):1967-78.


Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.

Essmann F, Pohlmann S, Gillissen B, Daniel PT, Schulze-Osthoff K, Jänicke RU.

J Biol Chem. 2005 Nov 4;280(44):37169-77. Epub 2005 Sep 7.


Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner.

Engels IH, Totzke G, Fischer U, Schulze-Osthoff K, Jänicke RU.

Mol Cell Biol. 2005 Apr;25(7):2808-18.


Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis.

Sohn D, Schulze-Osthoff K, Jänicke RU.

J Biol Chem. 2005 Feb 18;280(7):5267-73. Epub 2004 Dec 15.


Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation.

Essmann F, Bantel H, Totzke G, Engels IH, Sinha B, Schulze-Osthoff K, Jänicke RU.

Cell Death Differ. 2003 Nov;10(11):1260-72.


A rapid nonradioactive peptide phosphorylation assay.

Zeller M, Essmann F, Jänicke RU, Schulze-Osthoff K, König S.

J Exp Ther Oncol. 2003 Mar-Apr;3(2):59-61.


Many cuts to ruin: a comprehensive update of caspase substrates.

Fischer U, Jänicke RU, Schulze-Osthoff K.

Cell Death Differ. 2003 Jan;10(1):76-100. Review.


Tributyltin (TBT) induces ultra-rapid caspase activation independent of apoptosome formation in human platelets.

Berg CP, Rothbart A, Lauber K, Stein GM, Engels IH, Belka C, Jänicke RU, Schulze-Osthoff K, Wesselborg S.

Oncogene. 2003 Feb 6;22(5):775-80.


Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.

Rehm M, Dussmann H, Janicke RU, Tavare JM, Kogel D, Prehn JH.

J Biol Chem. 2002 Jul 5;277(27):24506-14. Epub 2002 Apr 18.


alpha-Toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling.

Bantel H, Sinha B, Domschke W, Peters G, Schulze-Osthoff K, Jänicke RU.

J Cell Biol. 2001 Nov 12;155(4):637-48. Epub 2001 Nov 5.


Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells.

Jänicke RU, Engels IH, Dunkern T, Kaina B, Schulze-Osthoff K, Porter AG.

Oncogene. 2001 Aug 16;20(36):5043-53.


Caspases: more than just killers?

Los M, Stroh C, Jänicke RU, Engels IH, Schulze-Osthoff K.

Trends Immunol. 2001 Jan;22(1):31-4. Review.


Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.

Engels IH, Stepczynska A, Stroh C, Lauber K, Berg C, Schwenzer R, Wajant H, Jänicke RU, Porter AG, Belka C, Gregor M, Schulze-Osthoff K, Wesselborg S.

Oncogene. 2000 Sep 21;19(40):4563-73.


Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells.

Blanc C, Deveraux QL, Krajewski S, Jänicke RU, Porter AG, Reed JC, Jaggi R, Marti A.

Cancer Res. 2000 Aug 15;60(16):4386-90.


Caspase-3 is necessary and sufficient for cleavage of protein synthesis eukaryotic initiation factor 4G during apoptosis.

Bushell M, McKendrick L, Jänicke RU, Clemens MJ, Morley SJ.

FEBS Lett. 1999 May 28;451(3):332-6.


Emerging roles of caspase-3 in apoptosis.

Porter AG, Jänicke RU.

Cell Death Differ. 1999 Feb;6(2):99-104. Review.


Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10.

Ng PW, Porter AG, Jänicke RU.

J Biol Chem. 1999 Apr 9;274(15):10301-8.


Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

Yang X, Stennicke HR, Wang B, Green DR, Jänicke RU, Srinivasan A, Seth P, Salvesen GS, Froelich CJ.

J Biol Chem. 1998 Dec 18;273(51):34278-83.

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