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Items: 1 to 50 of 408

1.

A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice.

Das K, Eisel D, Vormehr M, Müller-Decker K, Hommertgen A, Jäger D, Zörnig I, Feuerer M, Kopp-Schneider A, Osen W, Eichmüller SB.

BMC Cancer. 2019 Sep 13;19(1):914. doi: 10.1186/s12885-019-6102-6.

PMID:
31519152
2.

Sjögren's syndrome is not a risk factor for periodontal disease: a systematic review.

Maarse F, Jager DHJ, Alterch S, Korfage A, Forouzanfar T, Vissink A, Brand HS.

Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):225-233. Epub 2019 Aug 28. Review.

3.

Antibody responses to cancer antigens identify patients with a poor prognosis among HPV-positive and HPV-negative head and neck squamous cell carcinoma patients.

Laban S, Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende CC, Dyckhoff G, Boscolo-Rizzo P, Ezić J, Marienfeld R, Möller P, Kraus JM, Völkel G, Kestler HA, Brunner C, Schuler PJ, Wigand MC, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Waterboer T, Butt J.

Clin Cancer Res. 2019 Aug 23. pii: clincanres.1490.2019. doi: 10.1158/1078-0432.CCR-19-1490. [Epub ahead of print]

PMID:
31444248
4.
5.

CCR5 status and metastatic progression in colorectal cancer.

Suarez-Carmona M, Chaorentong P, Kather JN, Rothenheber R, Ahmed A, Berthel A, Heinzelmann A, Moraleda R, Valous NA, Kosaloglu Z, Eurich R, Wolf J, Grauling-Halama S, Hundemer M, Lasitschka F, Klupp F, Kahlert C, Ulrich A, Schneider M, Falk C, Jäger D, Zoernig I, Halama N.

Oncoimmunology. 2019 Jul 13;8(9):e1626193. doi: 10.1080/2162402X.2019.1626193. eCollection 2019.

6.

Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status.

Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende C, Dyckhoff G, Boscolo-Rizzo P, Ezic J, Marienfeld RB, Möller P, Völkel G, Kraus JM, Kestler HA, Brunner C, Schuler PJ, Wigand M, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Butt J, Waterboer T, Laban S.

Int J Cancer. 2019 Aug 12. doi: 10.1002/ijc.32623. [Epub ahead of print]

PMID:
31407331
7.

[Early oral symptoms of Parkinson's disease].

Jager DHJ, Verhoeff MC, van Dijk KD, de Baat C.

Ned Tijdschr Tandheelkd. 2019 Jul;126(7-8):363-368. doi: 10.5177/ntvt.2019.07/08.19033. Dutch.

PMID:
31309934
8.

Cancer Patients' Preferences for either Quality of Life or a Longer Life Determine Their Willingness to Talk about Forgoing Cancer-Specific Treatment.

Laryionava K, Hartmann M, Sklenarova H, Heussner P, Villalobos M, Jäger D, Winkler EC.

Oncol Res Treat. 2019;42(9):458-465. doi: 10.1159/000501129. Epub 2019 Jul 10.

PMID:
31291638
9.

Clinical Activity, Tolerability, and Long-term Follow-up of Durvalumab in Patients With Advanced NSCLC.

Antonia SJ, Balmanoukian A, Brahmer J, Ou SI, Hellmann MD, Kim SW, Ahn MJ, Kim DW, Gutierrez M, Liu SV, Schöffski P, Jäger D, Jamal R, Jerusalem G, Lutzky J, Nemunaitis J, Calabro L, Weiss J, Gadgeel S, Bhosle J, Ascierto PA, Rebelatto MC, Narwal R, Liang M, Xiao F, Antal J, Abdullah S, Angra N, Gupta AK, Khleif SN, Segal NH.

J Thorac Oncol. 2019 Jun 19. pii: S1556-0864(19)30475-7. doi: 10.1016/j.jtho.2019.06.010. [Epub ahead of print]

10.

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.

Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T.

Nat Med. 2019 Jul;25(7):1054-1056. doi: 10.1038/s41591-019-0462-y. Epub 2019 Jun 3.

PMID:
31160815
11.

Wound dehiscences following pre-implant bone augmentation with autogenous iliac crest bone grafts: A retrospective cohort study.

Jager DHJ, Maarse F, Klausch T, Karagozoglu KH, Ten Bruggenkate CM, Sándor GK, Wolff J, Schulten EAJM.

Int J Oral Implantol (New Malden). 2019;12(2):227-236.

PMID:
31090752
12.

Impact of post-surgical freezing delay on brain tumor metabolomics.

Mock A, Rapp C, Warta R, Abdollahi A, Jäger D, Sakowitz O, Brors B, von Deimling A, Jungk C, Unterberg A, Herold-Mende C.

Metabolomics. 2019 May 13;15(5):78. doi: 10.1007/s11306-019-1541-2.

PMID:
31087206
13.

Addition of platinum derivatives to fluoropyrimidine-based neoadjuvant chemoradiotherapy for stage II/III rectal cancer: systematic review and meta-analysis.

Hüttner FJ, Probst P, Kalkum E, Hackbusch M, Jensen K, Ulrich A, Debus J, Jäger D, Diener MK.

J Natl Cancer Inst. 2019 May 11. pii: djz081. doi: 10.1093/jnci/djz081. [Epub ahead of print]

PMID:
31077329
14.

Preclinical evaluation of peptide-based radiotracers for integrin αvβ6-positive pancreatic carcinoma.

Müller M, Altmann A, Sauter M, Lindner T, Jäger D, Rathke H, Herold-Mende C, Marmé F, Babich J, Mier W, Haberkorn U.

Nuklearmedizin. 2019 Aug;58(4):309-318. doi: 10.1055/a-0894-4127. Epub 2019 May 10.

PMID:
31075798
15.

Mismatch Repair Deficiency Drives Durable Complete Remission by Targeting Programmed Death Receptor 1 in a Metastatic Luminal Breast Cancer Patient.

Fremd C, Hlevnjak M, Zapatka M, Zoernig I, Halama N, Fejzibegovic N, Thewes V, Lichter P, Schirmacher P, Kloor M, Marmé F, Schütz F, Kosaloglu Z, Sinn HP, Jäger D, Schneeweiss A.

Breast Care (Basel). 2019 Mar;14(1):53-59. doi: 10.1159/000492580. Epub 2018 Nov 14.

PMID:
31019444
16.

68Ga-FAPI PET/CT: Tracer Uptake in 28 Different Kinds of Cancer.

Kratochwil C, Flechsig P, Lindner T, Abderrahim L, Altmann A, Mier W, Adeberg S, Rathke H, Röhrich M, Winter H, Plinkert PK, Marme F, Lang M, Kauczor HU, Jäger D, Debus J, Haberkorn U, Giesel FL.

J Nucl Med. 2019 Jun;60(6):801-805. doi: 10.2967/jnumed.119.227967. Epub 2019 Apr 6.

PMID:
30954939
17.

Chemotherapy for pancreatic cancer.

Springfeld C, Jäger D, Büchler MW, Strobel O, Hackert T, Palmer DH, Neoptolemos JP.

Presse Med. 2019 Mar;48(3 Pt 2):e159-e174. doi: 10.1016/j.lpm.2019.02.025. Epub 2019 Mar 15. Review.

PMID:
30879894
18.

Comparison of the Incidence and Severity of Traumatic Brain Injury Caused by Electrical Bicycle and Bicycle Accidents-A Retrospective Cohort Study From a Swiss Level I Trauma Center.

Baschera D, Jäger D, Preda R, Z'Graggen WJ, Raabe A, Exadaktylos AK, Hasler RM.

World Neurosurg. 2019 Mar 9. pii: S1878-8750(19)30658-8. doi: 10.1016/j.wneu.2019.03.032. [Epub ahead of print]

PMID:
30857998
19.

Analysis of the CDK4/6 Cell Cycle Pathway in Leiomyosarcomas as a Potential Target for Inhibition by Palbociclib.

Böhm MJ, Marienfeld R, Jäger D, Mellert K, von Witzleben A, Brüderlein S, Wittau M, von Baer A, Schultheiss M, Mayer-Steinacker R, Rücker FG, Möller P, Bullinger L, Barth TFE.

Sarcoma. 2019 Jan 21;2019:3914232. doi: 10.1155/2019/3914232. eCollection 2019.

20.

Idelalisib for optimized CD19-specific chimeric antigen receptor T cells in chronic lymphocytic leukemia patients.

Stock S, Übelhart R, Schubert ML, Fan F, He B, Hoffmann JM, Wang L, Wang S, Gong W, Neuber B, Hückelhoven-Krauss A, Gern U, Christ C, Hexel M, Schmitt A, Schmidt P, Krauss J, Jäger D, Müller-Tidow C, Dreger P, Schmitt M, Sellner L.

Int J Cancer. 2019 Sep 1;145(5):1312-1324. doi: 10.1002/ijc.32201. Epub 2019 Feb 28.

PMID:
30737788
21.

Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate.

Apostolidis L, Nientiedt C, Winkler EC, Berger AK, Kratochwil C, Kaiser A, Becker AS, Jäger D, Hohenfellner M, Hüttenbrink C, Pahernik S, Distler FA, Grüllich C.

Oncotarget. 2019 Jan 1;10(1):17-29. doi: 10.18632/oncotarget.26523. eCollection 2019 Jan 1.

22.

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study.

Kather JN, Krisam J, Charoentong P, Luedde T, Herpel E, Weis CA, Gaiser T, Marx A, Valous NA, Ferber D, Jansen L, Reyes-Aldasoro CC, Zörnig I, Jäger D, Brenner H, Chang-Claude J, Hoffmeister M, Halama N.

PLoS Med. 2019 Jan 24;16(1):e1002730. doi: 10.1371/journal.pmed.1002730. eCollection 2019 Jan.

23.

Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression.

Apostolidis L, Pfeiffenberger J, Gotthardt D, Radeleff B, Mehrabi A, Schemmer P, Jäger D, Schirmacher P, Stremmel W, Schulze-Bergkamen H, Springfeld C, Weiss KH.

Gastrointest Tumors. 2018 Sep;5(1-2):38-46. doi: 10.1159/000487635. Epub 2018 Apr 11.

24.

Surgical wound immunotherapy.

Liebers R, Jäger D.

Nat Nanotechnol. 2019 Jan;14(1):7-8. doi: 10.1038/s41565-018-0328-3. No abstract available.

PMID:
30531989
25.

Stereoselective synthesis and antiproliferative activity of the isomeric sphinganine analogues.

Čonková M, Martinková M, Gonda J, Jacková D, Pilátová MB, Kupka D, Jáger D.

Carbohydr Res. 2019 Jan 15;472:76-85. doi: 10.1016/j.carres.2018.09.008. Epub 2018 Nov 28.

PMID:
30529492
26.

Prognostic significance of microsatellite-instability in gastric and gastroesophageal junction cancer patients undergoing neoadjuvant chemotherapy.

Haag GM, Czink E, Ahadova A, Schmidt T, Sisic L, Blank S, Heger U, Apostolidis L, Berger AK, Springfeld C, Lasitschka F, Jäger D, von Knebel Doeberitz M, Kloor M.

Int J Cancer. 2019 Apr 1;144(7):1697-1703. doi: 10.1002/ijc.32030. Epub 2019 Jan 4.

PMID:
30499151
27.

Immunotherapy with ipilimumab plus nivolumab in a stage IV melanoma patient during pregnancy.

Menzer C, Beedgen B, Rom J, Duffert CM, Volckmar AL, Sedlaczek O, Richtig E, Enk A, Jäger D, Hassel JC.

Eur J Cancer. 2018 Nov;104:239-242. doi: 10.1016/j.ejca.2018.09.008. Epub 2018 Oct 25. No abstract available.

PMID:
30454709
28.

Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.

Elßner C, Goeppert B, Longerich T, Scherr AL, Stindt J, Nanduri LK, Rupp C, Kather JN, Schmitt N, Kautz N, Breuhahn K, Ismail L, Heide D, Hetzer J, García-Beccaria M, Hövelmeyer N, Waisman A, Urbanik T, Mueller S, Gdynia G, Banales JM, Roessler S, Schirmacher P, Jäger D, Schölch S, Keitel V, Heikenwalder M, Schulze-Bergkamen H, Köhler BC.

Gastroenterology. 2019 Mar;156(4):1190-1205.e14. doi: 10.1053/j.gastro.2018.11.018. Epub 2018 Nov 13.

PMID:
30445013
29.

Correlation between genomic index lesions and mpMRI and 68Ga-PSMA-PET/CT imaging features in primary prostate cancer.

Kesch C, Radtke JP, Wintsche A, Wiesenfarth M, Luttje M, Gasch C, Dieffenbacher S, Pecqueux C, Teber D, Hatiboglu G, Nyarangi-Dix J, Simpfendörfer T, Schönberg G, Dimitrakopoulou-Strauss A, Freitag M, Duensing A, Grüllich C, Jäger D, Götz M, Grabe N, Schweiger MR, Pahernik S, Perner S, Herpel E, Roth W, Wieczorek K, Maier-Hein K, Debus J, Haberkorn U, Giesel F, Galle J, Hadaschik B, Schlemmer HP, Hohenfellner M, Bonekamp D, Sültmann H, Duensing S.

Sci Rep. 2018 Nov 12;8(1):16708. doi: 10.1038/s41598-018-35058-3.

30.

HLA-E Peptide Repertoire and Dimorphism-Centerpieces in the Adaptive NK Cell Puzzle?

Rölle A, Jäger D, Momburg F.

Front Immunol. 2018 Oct 17;9:2410. doi: 10.3389/fimmu.2018.02410. eCollection 2018.

31.

Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer.

Vallet S, Fan F, Malvestiti S, Pecherstorfer M, Sattler M, Schneeweiss A, Schulze-Bergkamen H, Opferman JT, Cardone MH, Jäger D, Podar K.

Breast Cancer Res Treat. 2019 Feb;173(3):585-596. doi: 10.1007/s10549-018-5022-5. Epub 2018 Oct 29.

PMID:
30374681
32.

Optimizing the outcomes of pancreatic cancer surgery.

Strobel O, Neoptolemos J, Jäger D, Büchler MW.

Nat Rev Clin Oncol. 2019 Jan;16(1):11-26. doi: 10.1038/s41571-018-0112-1. Review.

PMID:
30341417
33.

Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer.

Jauch SF, Riethdorf S, Sprick MR, Schütz F, Schönfisch B, Brucker SY, Deutsch TM, Nees J, Saini M, Becker LM, Burwinkel B, Sinn P, Marmé F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A.

Breast Cancer Res Treat. 2019 Jan;173(1):155-165. doi: 10.1007/s10549-018-4972-y. Epub 2018 Oct 1.

PMID:
30276763
34.

Topography of cancer-associated immune cells in human solid tumors.

Kather JN, Suarez-Carmona M, Charoentong P, Weis CA, Hirsch D, Bankhead P, Horning M, Ferber D, Kel I, Herpel E, Schott S, Zörnig I, Utikal J, Marx A, Gaiser T, Brenner H, Chang-Claude J, Hoffmeister M, Jäger D, Halama N.

Elife. 2018 Sep 4;7. pii: e36967. doi: 10.7554/eLife.36967.

35.

Tooth loss in Sjögren's syndrome patients compared to age and gender matched controls.

Maarse F, Jager DH, Forouzanfar T, Wolff J, Brand HS.

Med Oral Patol Oral Cir Bucal. 2018 Sep 1;23(5):e545-e551. doi: 10.4317/medoral.22545.

36.

Distinct HLA-E Peptide Complexes Modify Antibody-Driven Effector Functions of Adaptive NK Cells.

Rölle A, Meyer M, Calderazzo S, Jäger D, Momburg F.

Cell Rep. 2018 Aug 21;24(8):1967-1976.e4. doi: 10.1016/j.celrep.2018.07.069.

37.

Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins.

Kuan SL, Fischer S, Hafner S, Wang T, Syrovets T, Liu W, Tokura Y, Ng DYW, Riegger A, Förtsch C, Jäger D, Barth TFE, Simmet T, Barth H, Weil T.

Adv Sci (Weinh). 2018 Jun 14;5(8):1701036. doi: 10.1002/advs.201701036. eCollection 2018 Aug.

38.

Synthesis of the cytotoxic phytosphingosines and their isomeric analogues.

Raschmanová JŠ, Martinková M, Gonda J, Pilátová MB, Kupka D, Jáger D.

Carbohydr Res. 2018 Oct;468:1-12. doi: 10.1016/j.carres.2018.08.001. Epub 2018 Aug 6.

PMID:
30120993
39.

Prognostic differences in 8th edition TNM staging of esophagogastric adenocarcinoma after neoadjuvant treatment.

Sisic L, Blank S, Nienhüser H, Dorr S, Haag GM, Jäger D, Bruckner T, Müller-Stich BP, Ott K, Büchler MW, Ulrich A, Schmidt T.

Eur J Surg Oncol. 2018 Oct;44(10):1646-1656. doi: 10.1016/j.ejso.2018.06.030. Epub 2018 Jul 7.

PMID:
30082176
40.

68Ga-FAPI PET/CT: Biodistribution and Preliminary Dosimetry Estimate of 2 DOTA-Containing FAP-Targeting Agents in Patients with Various Cancers.

Giesel FL, Kratochwil C, Lindner T, Marschalek MM, Loktev A, Lehnert W, Debus J, Jäger D, Flechsig P, Altmann A, Mier W, Haberkorn U.

J Nucl Med. 2019 Mar;60(3):386-392. doi: 10.2967/jnumed.118.215913. Epub 2018 Aug 2.

41.

HiGHmed - An Open Platform Approach to Enhance Care and Research across Institutional Boundaries.

Haarbrandt B, Schreiweis B, Rey S, Sax U, Scheithauer S, Rienhoff O, Knaup-Gregori P, Bavendiek U, Dieterich C, Brors B, Kraus I, Thoms CM, Jäger D, Ellenrieder V, Bergh B, Yahyapour R, Eils R, Consortium H, Marschollek M.

Methods Inf Med. 2018 Jul;57(S 01):e66-e81. doi: 10.3414/ME18-02-0002. Epub 2018 Jul 17.

42.

Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell.

Biere N, Ghaffar M, Doebbe A, Jäger D, Rothe N, Friedrich BM, Hofestädt R, Schreiber F, Kruse O, Sommer B.

J Integr Bioinform. 2018 Jul 11;15(2). pii: /j/jib.2018.15.issue-2/jib-2018-0003/jib-2018-0003.xml. doi: 10.1515/jib-2018-0003.

43.

Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites.

Leber MF, Baertsch MA, Anker SC, Henkel L, Singh HM, Bossow S, Engeland CE, Barkley R, Hoyler B, Albert J, Springfeld C, Jäger D, von Kalle C, Ungerechts G.

Mol Ther Oncolytics. 2018 Apr 12;9:30-40. doi: 10.1016/j.omto.2018.04.002. eCollection 2018 Jun 29.

44.

Early metabolic response in sequential FDG-PET/CT under cetuximab is a predictive marker for clinical response in first-line metastatic colorectal cancer patients: results of the phase II REMOTUX trial.

Berger AK, Lücke S, Abel U, Haag GM, Grüllich C, Stange A, Dietrich M, Apostolidis L, Freitag A, Trierweiler C, von Gall C, Ose J, Giesel F, Weber TF, Lordick F, Haberkorn U, Jäger D.

Br J Cancer. 2018 Jul;119(2):170-175. doi: 10.1038/s41416-018-0152-4. Epub 2018 Jul 2.

45.

Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy.

Kather JN, Berghoff AS, Ferber D, Suarez-Carmona M, Reyes-Aldasoro CC, Valous NA, Rojas-Moraleda R, Jäger D, Halama N.

Oncoimmunology. 2018 Mar 29;7(7):e1444412. doi: 10.1080/2162402X.2018.1444412. eCollection 2018.

46.

Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC18961 trial.

Michels J, Becker N, Suciu S, Kaiser I, Benner A, Kosaloglu-Yalcin Z, Agoussi S, Halama N, Pawlita M, Waterboer T, Eichmüller SB, Jäger D, Eggermont AMM, Zörnig I.

Oncoimmunology. 2018 Feb 12;7(6):e1428157. doi: 10.1080/2162402X.2018.1428157. eCollection 2018.

47.

Survival outcomes of patients with germ cell tumors treated with high-dose chemotherapy for refractory or relapsing disease.

Zschäbitz S, Distler FA, Krieger B, Wuchter P, Schäfer-Eckart K, Jenzer M, Hohenfellner M, Dreger P, Haag GM, Jäger D, Pahernik S, Grüllich C.

Oncotarget. 2018 Apr 27;9(32):22537-22545. doi: 10.18632/oncotarget.25162. eCollection 2018 Apr 27.

48.

An undifferentiated carcinoma at Klatskin-position with long-term complete remission after chemotherapy.

Köhler BC, Goeppert B, Waldburger N, Schlamp K, Sauer P, Jäger D, Weiss KH, Macher-Göppinger S, Schulze-Bergkamen H, Schirmacher P, Springfeld C.

Oncotarget. 2018 Apr 24;9(31):22230-22235. doi: 10.18632/oncotarget.25125. eCollection 2018 Apr 24.

49.

Genomic features of renal cell carcinoma with venous tumor thrombus.

Warsow G, Hübschmann D, Kleinheinz K, Nientiedt C, Heller M, Van Coile L, Tolstov Y, Trennheuser L, Wieczorek K, Pecqueux C, Gasch C, Kuru T, Nyarangi-Dix J, Hatiboglu G, Teber D, Perner S, Stenzinger A, Roth W, Hadaschik B, Pahernik S, Jäger D, Grüllich C, Duensing A, Eils R, Schlesner M, Sültmann H, Hohenfellner M, Duensing S.

Sci Rep. 2018 May 10;8(1):7477. doi: 10.1038/s41598-018-25544-z.

50.

MetaboDiff: an R package for differential metabolomic analysis.

Mock A, Warta R, Dettling S, Brors B, Jäger D, Herold-Mende C.

Bioinformatics. 2018 Oct 1;34(19):3417-3418. doi: 10.1093/bioinformatics/bty344.

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