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Items: 1 to 50 of 368

1.

HiGHmed - An Open Platform Approach to Enhance Care and Research across Institutional Boundaries.

Haarbrandt B, Schreiweis B, Rey S, Sax U, Scheithauer S, Rienhoff O, Knaup-Gregori P, Bavendiek U, Dieterich C, Brors B, Kraus I, Thoms CM, Jäger D, Ellenrieder V, Bergh B, Yahyapour R, Eils R, Consortium H, Marschollek M.

Methods Inf Med. 2018 Jul;57(S 01):e66-e81. doi: 10.3414/ME18-02-0002. Epub 2018 Jul 17.

2.

Heuristic Modeling and 3D Stereoscopic Visualization of a Chlamydomonas reinhardtii Cell.

Biere N, Ghaffar M, Doebbe A, Jäger D, Rothe N, Friedrich BM, Hofestädt R, Schreiber F, Kruse O, Sommer B.

J Integr Bioinform. 2018 Jul 11;15(2). pii: /j/jib.2018.15.issue-2/jib-2018-0003/jib-2018-0003.xml. doi: 10.1515/jib-2018-0003.

PMID:
30001212
3.

Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites.

Leber MF, Baertsch MA, Anker SC, Henkel L, Singh HM, Bossow S, Engeland CE, Barkley R, Hoyler B, Albert J, Springfeld C, Jäger D, von Kalle C, Ungerechts G.

Mol Ther Oncolytics. 2018 Apr 12;9:30-40. doi: 10.1016/j.omto.2018.04.002. eCollection 2018 Jun 29.

4.

Early metabolic response in sequential FDG-PET/CT under cetuximab is a predictive marker for clinical response in first-line metastatic colorectal cancer patients: results of the phase II REMOTUX trial.

Berger AK, Lücke S, Abel U, Haag GM, Grüllich C, Stange A, Dietrich M, Apostolidis L, Freitag A, Trierweiler C, von Gall C, Ose J, Giesel F, Weber TF, Lordick F, Haberkorn U, Jäger D.

Br J Cancer. 2018 Jul;119(2):170-175. doi: 10.1038/s41416-018-0152-4. Epub 2018 Jul 2.

PMID:
29961759
5.

Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy.

Kather JN, Berghoff AS, Ferber D, Suarez-Carmona M, Reyes-Aldasoro CC, Valous NA, Rojas-Moraleda R, Jäger D, Halama N.

Oncoimmunology. 2018 Mar 29;7(7):e1444412. doi: 10.1080/2162402X.2018.1444412. eCollection 2018.

6.

Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC18961 trial.

Michels J, Becker N, Suciu S, Kaiser I, Benner A, Kosaloglu-Yalcin Z, Agoussi S, Halama N, Pawlita M, Waterboer T, Eichmüller SB, Jäger D, Eggermont AMM, Zörnig I.

Oncoimmunology. 2018 Feb 12;7(6):e1428157. doi: 10.1080/2162402X.2018.1428157. eCollection 2018.

7.

Survival outcomes of patients with germ cell tumors treated with high-dose chemotherapy for refractory or relapsing disease.

Zschäbitz S, Distler FA, Krieger B, Wuchter P, Schäfer-Eckart K, Jenzer M, Hohenfellner M, Dreger P, Haag GM, Jäger D, Pahernik S, Grüllich C.

Oncotarget. 2018 Apr 27;9(32):22537-22545. doi: 10.18632/oncotarget.25162. eCollection 2018 Apr 27.

8.

An undifferentiated carcinoma at Klatskin-position with long-term complete remission after chemotherapy.

Köhler BC, Goeppert B, Waldburger N, Schlamp K, Sauer P, Jäger D, Weiss KH, Macher-Göppinger S, Schulze-Bergkamen H, Schirmacher P, Springfeld C.

Oncotarget. 2018 Apr 24;9(31):22230-22235. doi: 10.18632/oncotarget.25125. eCollection 2018 Apr 24.

9.

Genomic features of renal cell carcinoma with venous tumor thrombus.

Warsow G, Hübschmann D, Kleinheinz K, Nientiedt C, Heller M, Van Coile L, Tolstov Y, Trennheuser L, Wieczorek K, Pecqueux C, Gasch C, Kuru T, Nyarangi-Dix J, Hatiboglu G, Teber D, Perner S, Stenzinger A, Roth W, Hadaschik B, Pahernik S, Jäger D, Grüllich C, Duensing A, Eils R, Schlesner M, Sültmann H, Hohenfellner M, Duensing S.

Sci Rep. 2018 May 10;8(1):7477. doi: 10.1038/s41598-018-25544-z.

10.

MetaboDiff: an R package for differential metabolomic analysis.

Mock A, Warta R, Dettling S, Brors B, Jäger D, Herold-Mende C.

Bioinformatics. 2018 Apr 26. doi: 10.1093/bioinformatics/bty344. [Epub ahead of print]

PMID:
29718102
11.

A new method for tumor imaging by targeting cancer associated fibroblasts.

Loktev A, Lindner T, Mier W, Debus J, Altmann A, Jäger D, Giesel F, Kratochwil C, Barthe P, Roumestand C, Haberkorn U.

J Nucl Med. 2018 Apr 6. pii: jnumed.118.210435. doi: 10.2967/jnumed.118.210435. [Epub ahead of print]

PMID:
29626120
12.

Development of quinoline based theranostic ligands for the targeting of fibroblast activation protein.

Lindner T, Loktev A, Altmann A, Giesel F, Kratochwil C, Debus J, Jäger D, Mier W, Haberkorn U.

J Nucl Med. 2018 Apr 6. pii: jnumed.118.210443. doi: 10.2967/jnumed.118.210443. [Epub ahead of print]

PMID:
29626119
13.

Sialendoscopy enhances salivary gland function in Sjögren's syndrome: a 6-month follow-up, randomised and controlled, single blind study.

Karagozoglu KH, Vissink A, Forouzanfar T, Brand HS, Maarse F, Jager DHJ.

Ann Rheum Dis. 2018 Jul;77(7):1025-1031. doi: 10.1136/annrheumdis-2017-212672. Epub 2018 Feb 23.

PMID:
29475854
14.

Clinical oral dryness score: evaluation of a new screening method for oral dryness.

Jager DHJ, Bots CP, Forouzanfar T, Brand HS.

Odontology. 2018 Jan 22. doi: 10.1007/s10266-018-0339-4. [Epub ahead of print]

PMID:
29356914
15.

Palliative chemotherapy for pancreatic adenocarcinoma: a retrospective cohort analysis of efficacy and toxicity of the FOLFIRINOX regimen focusing on the older patient.

Berger AK, Haag GM, Ehmann M, Byl A, Jäger D, Springfeld C.

BMC Gastroenterol. 2017 Dec 6;17(1):143. doi: 10.1186/s12876-017-0709-3.

16.

Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy.

Chen X, Bernemann C, Tolkach Y, Heller M, Nientiedt C, Falkenstein M, Herpel E, Jenzer M, Grüllich C, Jäger D, Sültmann H, Duensing A, Perner S, Cronauer MV, Stephan C, Debus J, Schrader AJ, Kristiansen G, Hohenfellner M, Duensing S.

Urol Oncol. 2018 Apr;36(4):161.e19-161.e30. doi: 10.1016/j.urolonc.2017.11.001. Epub 2017 Dec 1.

PMID:
29198908
17.

Highly efficient destruction of squamous carcinoma cells of the head and neck by photochemical internalization of Ranpirnase.

Liebers N, Holland-Letz T, Welschof M, Høgset A, Jäger D, Arndt MAE, Krauss J.

J Exp Ther Oncol. 2017 Nov;12(2):113-120.

PMID:
29161778
18.

U-CH17P, -M and -S, a new cell culture system for tumor diversity and progression in chordoma.

Jäger D, Lechel A, Tharehalli U, Seeling C, Möller P, Barth TFE, Mellert K.

Int J Cancer. 2018 Apr 1;142(7):1369-1378. doi: 10.1002/ijc.31161. Epub 2017 Nov 27.

PMID:
29148152
19.

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response.

Muckenhuber A, Berger AK, Schlitter AM, Steiger K, Konukiewitz B, Trumpp A, Eils R, Werner J, Friess H, Esposito I, Klöppel G, Ceyhan GO, Jesinghaus M, Denkert C, Bahra M, Stenzinger A, Sprick MR, Jäger D, Springfeld C, Weichert W.

Clin Cancer Res. 2018 Jan 15;24(2):351-359. doi: 10.1158/1078-0432.CCR-17-2180. Epub 2017 Nov 3.

PMID:
29101303
20.

Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy.

Dietz S, Sültmann H, Du Y, Reisinger E, Riediger AL, Volckmar AL, Stenzinger A, Schlesner M, Jäger D, Hohenfellner M, Duensing S, Grüllich C, Pahernik S.

Oncotarget. 2017 May 23;8(43):74049-74057. doi: 10.18632/oncotarget.18200. eCollection 2017 Sep 26.

21.

Degradation of Reactive Black 5 by electrochemical oxidation.

Jager D, Kupka D, Vaclavikova M, Ivanicova L, Gallios G.

Chemosphere. 2018 Jan;190:405-416. doi: 10.1016/j.chemosphere.2017.09.126. Epub 2017 Sep 27.

PMID:
29024885
22.

Liver cancers with stem/progenitor-cell features - a rare chemotherapy-sensitive malignancy.

Köhler BC, Waldburger N, Schlamp K, Jäger D, Weiss KH, Schulze-Bergkamen H, Schirmacher P, Springfeld C.

Oncotarget. 2017 Jun 5;8(35):59991-59998. doi: 10.18632/oncotarget.19000. eCollection 2017 Aug 29.

23.

Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe).

Hassel JC, Jiang H, Bender C, Winkler J, Sevko A, Shevchenko I, Halama N, Dimitrakopoulou-Strauss A, Haefeli WE, Jäger D, Enk A, Utikal J, Umansky V.

Oncoimmunology. 2017 May 16;6(9):e1326440. doi: 10.1080/2162402X.2017.1326440. eCollection 2017.

24.

In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer.

Kather JN, Poleszczuk J, Suarez-Carmona M, Krisam J, Charoentong P, Valous NA, Weis CA, Tavernar L, Leiss F, Herpel E, Klupp F, Ulrich A, Schneider M, Marx A, Jäger D, Halama N.

Cancer Res. 2017 Nov 15;77(22):6442-6452. doi: 10.1158/0008-5472.CAN-17-2006. Epub 2017 Sep 18.

PMID:
28923860
25.

A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol.

Hajda J, Lehmann M, Krebs O, Kieser M, Geletneky K, Jäger D, Dahm M, Huber B, Schöning T, Sedlaczek O, Stenzinger A, Halama N, Daniel V, Leuchs B, Angelova A, Rommelaere J, Engeland CE, Springfeld C, Ungerechts G.

BMC Cancer. 2017 Aug 29;17(1):576. doi: 10.1186/s12885-017-3604-y.

26.

Dorsal root ganglia hypertrophy as in vivo correlate of oxaliplatin-induced polyneuropathy.

Apostolidis L, Schwarz D, Xia A, Weiler M, Heckel A, Godel T, Heiland S, Schlemmer HP, Jäger D, Bendszus M, Bäumer P.

PLoS One. 2017 Aug 24;12(8):e0183845. doi: 10.1371/journal.pone.0183845. eCollection 2017.

27.

A Tupaia paramyxovirus vector system for targeting and transgene expression.

Engeland CE, Bossow S, Hudacek AW, Hoyler B, Förster J, Veinalde R, Jäger D, Cattaneo R, Ungerechts G, Springfeld C.

J Gen Virol. 2017 Sep;98(9):2248-2257. doi: 10.1099/jgv.0.000887. Epub 2017 Sep 8.

PMID:
28809150
28.

Prevention of HPV-Related Oral Cancer by Dentists: Assessing the Opinion of Dutch Dental Students.

Poelman MR, Brand HS, Forouzanfar T, Daley EM, Jager DHJ.

J Cancer Educ. 2017 Jul 24. doi: 10.1007/s13187-017-1257-9. [Epub ahead of print]

PMID:
28741269
29.

Postoperative follow-up programs improve survival in curatively resected gastric and junctional cancer patients: a propensity score matched analysis.

Sisic L, Strowitzki MJ, Blank S, Nienhueser H, Dorr S, Haag GM, Jäger D, Ott K, Büchler MW, Ulrich A, Schmidt T.

Gastric Cancer. 2018 May;21(3):552-568. doi: 10.1007/s10120-017-0751-4. Epub 2017 Jul 24.

PMID:
28741059
30.

Morphological variation, phylogenetic relationships, and geographic distribution of the Baenidae (Testudines), based on new specimens from the Uinta Formation (Uinta Basin), Utah (USA).

Smith HF, Hutchison JH, Townsend KEB, Adrian B, Jager D.

PLoS One. 2017 Jul 7;12(7):e0180574. doi: 10.1371/journal.pone.0180574. eCollection 2017.

31.

The postoperative part of perioperative chemotherapy fails to provide a survival benefit in completely resected esophagogastric adenocarcinoma.

Sisic L, Blank S, Nienhüser H, Haag GM, Jäger D, Bruckner T, Ott K, Schmidt T, Ulrich A.

Surg Oncol. 2017 Jun 29. pii: S0960-7404(17)30119-6. doi: 10.1016/j.suronc.2017.06.001. [Epub ahead of print]

PMID:
28684226
32.

Mutations in BRCA2 and taxane resistance in prostate cancer.

Nientiedt C, Heller M, Endris V, Volckmar AL, Zschäbitz S, Tapia-Laliena MA, Duensing A, Jäger D, Schirmacher P, Sültmann H, Stenzinger A, Hohenfellner M, Grüllich C, Duensing S.

Sci Rep. 2017 Jul 4;7(1):4574. doi: 10.1038/s41598-017-04897-x.

33.

Resistance training as supportive measure in advanced cancer patients undergoing TKI therapy-a controlled feasibility trial.

Rosenberger F, Wiskemann J, Vallet S, Haag GM, Schembri E, Jäger D, Grüllich C.

Support Care Cancer. 2017 Dec;25(12):3655-3664. doi: 10.1007/s00520-017-3788-3. Epub 2017 Jun 30.

PMID:
28667563
34.

Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer.

Czink E, Kloor M, Goeppert B, Fröhling S, Uhrig S, Weber TF, Meinel J, Sutter C, Weiss KH, Schirmacher P, Doeberitz MVK, Jäger D, Springfeld C.

Cold Spring Harb Mol Case Stud. 2017 Sep 1;3(5). pii: a001974. doi: 10.1101/mcs.a001974. Print 2017 Sep.

35.

HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas.

Jäger D, Barth TFE, Brüderlein S, Scheuerle A, Rinner B, von Witzleben A, Lechel A, Meyer P, Mayer-Steinacker R, Baer AV, Schultheiss M, Wirtz CR, Möller P, Mellert K.

Sci Rep. 2017 May 17;7(1):2032. doi: 10.1038/s41598-017-02174-5.

36.

Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation.

Veinalde R, Grossardt C, Hartmann L, Bourgeois-Daigneault MC, Bell JC, Jäger D, von Kalle C, Ungerechts G, Engeland CE.

Oncoimmunology. 2017 Jan 31;6(4):e1285992. doi: 10.1080/2162402X.2017.1285992. eCollection 2017.

37.

Friends and family: A software program for identification of unrelated individuals from molecular marker data.

de Jager D, Swarts P, Harper C, Bloomer P.

Mol Ecol Resour. 2017 Nov;17(6):e225-e233. doi: 10.1111/1755-0998.12691. Epub 2017 Jun 13.

PMID:
28503747
38.

Complications of Sialendoscopy in Patients With Sjögren Syndrome.

Karagozoglu KH, De Visscher JG, Forouzanfar T, van der Meij EH, Jager DJ.

J Oral Maxillofac Surg. 2017 May;75(5):978-983. doi: 10.1016/j.joms.2016.09.046. Epub 2016 Oct 6.

PMID:
28481749
39.

High prevalence of incidental and symptomatic venous thromboembolic events in patients with advanced pancreatic cancer under palliative chemotherapy: A retrospective cohort study.

Berger AK, Singh HM, Werft W, Muckenhuber A, Sprick MR, Trumpp A, Weichert W, Jäger D, Springfeld C.

Pancreatology. 2017 Jul - Aug;17(4):629-634. doi: 10.1016/j.pan.2017.04.012. Epub 2017 Apr 22.

PMID:
28462862
40.

Efficacy of Cabazitaxel Treatment in Metastatic Castration Resistant Prostate Cancer in Second and Later Lines. An Experience from Two German Centers.

Zschäbitz S, Vallet S, Hadaschik B, Debatin D, Fuxius S, Karcher A, Pahernik S, Spath C, Duensing S, Jäger D, Hohenfellner M, Grüllich C.

J Cancer. 2017 Feb 11;8(4):507-512. doi: 10.7150/jca.17644. eCollection 2017.

41.

sRNA154 a newly identified regulator of nitrogen fixation in Methanosarcina mazei strain Gö1.

Prasse D, Förstner KU, Jäger D, Backofen R, Schmitz RA.

RNA Biol. 2017 Nov 2;14(11):1544-1558. doi: 10.1080/15476286.2017.1306170. Epub 2017 Apr 27.

42.

Response to anti-programmed cell death protein-1 antibodies in men treated for platinum refractory germ cell cancer relapsed after high-dose chemotherapy and stem cell transplantation.

Zschäbitz S, Lasitschka F, Hadaschik B, Hofheinz RD, Jentsch-Ullrich K, Grüner M, Jäger D, Grüllich C.

Eur J Cancer. 2017 May;76:1-7. doi: 10.1016/j.ejca.2017.01.033. Epub 2017 Mar 4.

PMID:
28262583
44.

Targeting the Immune Niche within the Bone Marrow Microenvironment: The Rise of Immunotherapy in Multiple Myeloma.

Podar K, Jager D.

Curr Cancer Drug Targets. 2017;17(9):782-805. doi: 10.2174/1568009617666170214103834. Review.

PMID:
28201977
45.

Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases.

Koşaloğlu Z, Zörnig I, Halama N, Kaiser I, Buchhalter I, Grabe N, Eils R, Schlesner M, Califano A, Jäger D.

Oncoimmunology. 2016 Jul 22;5(11):e1213931. doi: 10.1080/2162402X.2016.1213931. eCollection 2016.

46.

Pancreatic Cancer Surgery: The New R-status Counts.

Strobel O, Hank T, Hinz U, Bergmann F, Schneider L, Springfeld C, Jäger D, Schirmacher P, Hackert T, Büchler MW.

Ann Surg. 2017 Mar;265(3):565-573. doi: 10.1097/SLA.0000000000001731.

PMID:
27918310
47.

Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification.

Gröschel S, Bommer M, Hutter B, Budczies J, Bonekamp D, Heining C, Horak P, Fröhlich M, Uhrig S, Hübschmann D, Geörg C, Richter D, Pfarr N, Pfütze K, Wolf S, Schirmacher P, Jäger D, von Kalle C, Brors B, Glimm H, Weichert W, Stenzinger A, Fröhling S.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001180.

48.

In silico SNP analysis of the breast cancer antigen NY-BR-1.

Kosaloglu Z, Bitzer J, Halama N, Huang Z, Zapatka M, Schneeweiss A, Jäger D, Zörnig I.

BMC Cancer. 2016 Nov 18;16(1):901.

49.
50.

Impact of resection and systemic therapy on the survival of patients with brain metastasis of metastatic renal cell carcinoma.

Du Y, Pahernik S, Hadaschik B, Teber D, Duensing S, Jäger D, Hohenfellner M, Grüllich C.

J Neurooncol. 2016 Oct;130(1):221-228. Epub 2016 Aug 18.

PMID:
27538910

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