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Items: 1 to 50 of 379

1.

Adult T-Cell Leukemia/Lymphoma-Related Ocular Manifestations: Analysis of the First Large-Scale Nationwide Survey.

Kamoi K, Okayama A, Izumo S, Hamaguchi I, Uchimaru K, Tojo A, Ohno-Matsui K.

Front Microbiol. 2019 Jan 8;9:3240. doi: 10.3389/fmicb.2018.03240. eCollection 2018.

2.

Multiple spotty lesions of the spinal cord in a Chinese patient with human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis.

Gao H, Ye X, Cai R, Xu Q, Liang L, Izumo S, Xing HQ, Kubota R.

Int J Infect Dis. 2018 Mar;68:1-3. doi: 10.1016/j.ijid.2017.12.022. Epub 2017 Dec 29.

3.

Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.

Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, Shichino S, Shiino T, Saito Y, Watanabe S, Sugimoto C, Kuroda MJ, Ato M, Nagai Y, Izumo S, Matsushima K, Miyazawa M, Ansari AA, Villinger F, Mori K.

J Virol. 2017 Jun 9;91(13). pii: e00439-17. doi: 10.1128/JVI.00439-17. Print 2017 Jul 1.

4.

Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis.

Nozuma S, Matsuura E, Kodama D, Tashiro Y, Matsuzaki T, Kubota R, Izumo S, Takashima H.

Retrovirology. 2017 Apr 19;14(1):26. doi: 10.1186/s12977-017-0350-9.

5.

Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells.

Wang J, Zhang Y, Xu Q, Qiu J, Zheng H, Ye X, Xue Y, Yin Y, Zhang Z, Liu Y, Hao Y, Wei Q, Wang W, Mori K, Izumo S, Kubota R, Shao Y, Xing HQ.

Oncotarget. 2017 Mar 14;8(11):18082-18094. doi: 10.18632/oncotarget.14993.

6.

Recapitulation of Clinical Individual Susceptibility to Drug-Induced QT Prolongation in Healthy Subjects Using iPSC-Derived Cardiomyocytes.

Shinozawa T, Nakamura K, Shoji M, Morita M, Kimura M, Furukawa H, Ueda H, Shiramoto M, Matsuguma K, Kaji Y, Ikushima I, Yono M, Liou SY, Nagai H, Nakanishi A, Yamamoto K, Izumo S.

Stem Cell Reports. 2017 Feb 14;8(2):226-234. doi: 10.1016/j.stemcr.2016.12.014. Epub 2017 Jan 19.

8.

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): A comparative study to identify factors that influence disease progression.

Matsuura E, Nozuma S, Tashiro Y, Kubota R, Izumo S, Takashima H.

J Neurol Sci. 2016 Dec 15;371:112-116. doi: 10.1016/j.jns.2016.10.030. Epub 2016 Oct 21.

9.

Decrease of aquaporin-4 and excitatory amino acid transporter-2 indicate astrocyte dysfunction for pathogenesis of cortical degeneration in HIV-associated neurocognitive disorders.

Xing HQ, Zhang Y, Izumo K, Arishima S, Kubota R, Ye X, Xu Q, Mori K, Izumo S.

Neuropathology. 2017 Feb;37(1):25-34. doi: 10.1111/neup.12321. Epub 2016 Aug 10.

PMID:
27506782
10.

Correction: Familial Clusters of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.

Nozuma S, Matsuura E, Matsuzaki T, Watanabe O, Kubota R, Izumo S, Takashima H.

PLoS One. 2016 Mar 30;11(3):e0152954. doi: 10.1371/journal.pone.0152954. eCollection 2016. No abstract available.

11.

New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan.

Sakiyama Y, Kanda N, Higuchi Y, Yoshimura M, Wakaguri H, Takata Y, Watanabe O, Yuan J, Tashiro Y, Saigo R, Nozuma S, Yoshimura A, Arishima S, Ikeda K, Shinohara K, Arata H, Michizono K, Higashi K, Hashiguchi A, Okamoto Y, Hirano R, Shiraishi T, Matsuura E, Okubo R, Higuchi I, Goto M, Hirano H, Sano A, Iwasaki T, Matsuda F, Izumo S, Takashima H.

Neurol Neuroimmunol Neuroinflamm. 2015 Aug 13;2(5):e143. doi: 10.1212/NXI.0000000000000143. eCollection 2015 Oct.

12.

Standardization of Quantitative PCR for Human T-Cell Leukemia Virus Type 1 in Japan: a Collaborative Study.

Kuramitsu M, Okuma K, Yamochi T, Sato T, Sasaki D, Hasegawa H, Umeki K, Kubota R, Sobata R, Matsumoto C, Kaneko N, Naruse I, Yamagishi M, Nakashima M, Momose H, Araki K, Mizukami T, Mizusawa S, Okada Y, Ochiai M, Utsunomiya A, Koh KR, Ogata M, Nosaka K, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Satake M, Okayama A, Mochizuki M, Izumo S, Saito S, Itabashi K, Kamihira S, Yamaguchi K, Watanabe T, Hamaguchi I.

J Clin Microbiol. 2015 Nov;53(11):3485-91. doi: 10.1128/JCM.01628-15. Epub 2015 Aug 19.

13.

Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.

Matsuura E, Kubota R, Tanaka Y, Takashima H, Izumo S.

J Neuropathol Exp Neurol. 2015 Jan;74(1):2-14. doi: 10.1097/NEN.0000000000000141.

14.

Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis.

Nozuma S, Matsuura E, Matsuzaki T, Watanabe O, Kubota R, Izumo S, Takashima H.

PLoS One. 2014 May 6;9(5):e86144. doi: 10.1371/journal.pone.0086144. eCollection 2014. Erratum in: PLoS One. 2016;11(3):e0152954.

15.

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis.

Sato T, Coler-Reilly A, Utsunomiya A, Araya N, Yagishita N, Ando H, Yamauchi J, Inoue E, Ueno T, Hasegawa Y, Nishioka K, Nakajima T, Jacobson S, Izumo S, Yamano Y.

PLoS Negl Trop Dis. 2013 Oct 10;7(10):e2479. doi: 10.1371/journal.pntd.0002479. eCollection 2013.

16.

Increased expression of OX40 is associated with progressive disease in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.

Saito M, Tanaka R, Arishima S, Matsuzaki T, Ishihara S, Tokashiki T, Ohya Y, Takashima H, Umehara F, Izumo S, Tanaka Y.

Retrovirology. 2013 May 7;10:51. doi: 10.1186/1742-4690-10-51.

17.

Hereditary sensory and autonomic neuropathy type IID caused by an SCN9A mutation.

Yuan J, Matsuura E, Higuchi Y, Hashiguchi A, Nakamura T, Nozuma S, Sakiyama Y, Yoshimura A, Izumo S, Takashima H.

Neurology. 2013 Apr 30;80(18):1641-9. doi: 10.1212/WNL.0b013e3182904fdd. Epub 2013 Apr 17.

PMID:
23596073
18.

Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma.

Hasui K, Wang J, Tanaka Y, Izumo S, Eizuru Y, Matsuyama T.

Acta Histochem Cytochem. 2012 Apr 26;45(2):83-106. doi: 10.1267/ahc.11034. Epub 2012 Apr 21.

19.

Human T-lymphotropic virus type I (HTLV-I)-specific CD8+ cells accumulate in the lungs of patients infected with HTLV-I with pulmonary involvement.

Kawabata T, Higashimoto I, Takashima H, Izumo S, Kubota R.

J Med Virol. 2012 Jul;84(7):1120-7. doi: 10.1002/jmv.23307.

PMID:
22585731
20.

Transcription factor GATA4 is activated but not required for insulin-like growth factor 1 (IGF1)-induced cardiac hypertrophy.

Bisping E, Ikeda S, Sedej M, Wakula P, McMullen JR, Tarnavski O, Sedej S, Izumo S, Pu WT, Pieske B.

J Biol Chem. 2012 Mar 23;287(13):9827-34. doi: 10.1074/jbc.M111.338749. Epub 2012 Jan 6.

21.

Immunohistochemistry of programmed cell death in archival human pathology specimens.

Hasui K, Nagai T, Wang J, Jia X, Aozasa K, Izumo S, Kawano Y, Kanekura T, Eizuru Y, Matsuyama T.

Cells. 2012 May 7;1(2):74-88. doi: 10.3390/cells1020074.

22.

Programmed death-1 (PD-1)/PD-1 ligand pathway-mediated immune responses against human T-lymphotropic virus type 1 (HTLV-1) in HTLV-1-associated myelopathy/tropical spastic paraparesis and carriers with autoimmune disorders.

Kozako T, Yoshimitsu M, Akimoto M, White Y, Matsushita K, Soeda S, Shimeno H, Kubota R, Izumo S, Arima N.

Hum Immunol. 2011 Nov;72(11):1001-6. doi: 10.1016/j.humimm.2011.07.308. Epub 2011 Aug 2.

PMID:
21851845
23.

Reduced Tim-3 expression on human T-lymphotropic virus type I (HTLV-I) Tax-specific cytotoxic T lymphocytes in HTLV-I infection.

Abdelbary NH, Abdullah HM, Matsuzaki T, Hayashi D, Tanaka Y, Takashima H, Izumo S, Kubota R.

J Infect Dis. 2011 Apr 1;203(7):948-59. doi: 10.1093/infdis/jiq153.

PMID:
21402546
24.

Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders.

Kozako T, Akimoto M, Toji S, White Y, Suzuki S, Arima T, Suruga Y, Matsushita K, Shimeno H, Soeda S, Kubota R, Izumo S, Uozumi K, Arima N.

J Med Virol. 2011 Mar;83(3):501-9. doi: 10.1002/jmv.21985.

PMID:
21264872
25.

Intra- and inter-laboratory variability in human T-cell leukemia virus type-1 proviral load quantification using real-time polymerase chain reaction assays: a multi-center study.

Kamihira S, Yamano Y, Iwanaga M, Sasaki D, Satake M, Okayama A, Umeki K, Kubota R, Izumo S, Yamaguchi K, Watanabe T.

Cancer Sci. 2010 Nov;101(11):2361-7. doi: 10.1111/j.1349-7006.2010.01720.x. Epub 2010 Sep 28.

26.

Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure.

Fujimura M, Usuki F, Kawamura M, Izumo S.

Toxicol Appl Pharmacol. 2011 Jan 1;250(1):1-9. doi: 10.1016/j.taap.2010.09.011. Epub 2010 Sep 24.

PMID:
20869980
27.

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.

Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY.

Circ Res. 2010 Nov 12;107(10):1275-89. doi: 10.1161/CIRCRESAHA.110.229054. Epub 2010 Sep 16.

PMID:
20847309
28.

Neuropathology of HTLV-1-associated myelopathy (HAM/TSP): The 50th Anniversary of Japanese Society of Neuropathology.

Izumo S.

Neuropathology. 2010 Oct;30(5):480-5. doi: 10.1111/j.1440-1789.2010.01135.x.

PMID:
20573027
29.

PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.

Lin RC, Weeks KL, Gao XM, Williams RB, Bernardo BC, Kiriazis H, Matthews VB, Woodcock EA, Bouwman RD, Mollica JP, Speirs HJ, Dawes IW, Daly RJ, Shioi T, Izumo S, Febbraio MA, Du XJ, McMullen JR.

Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):724-32. doi: 10.1161/ATVBAHA.109.201988.

PMID:
20237330
30.

Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction.

Buss SJ, Muenz S, Riffel JH, Malekar P, Hagenmueller M, Weiss CS, Bea F, Bekeredjian R, Schinke-Braun M, Izumo S, Katus HA, Hardt SE.

J Am Coll Cardiol. 2009 Dec 15;54(25):2435-46. doi: 10.1016/j.jacc.2009.08.031.

31.

Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation.

Pretorius L, Du XJ, Woodcock EA, Kiriazis H, Lin RC, Marasco S, Medcalf RL, Ming Z, Head GA, Tan JW, Cemerlang N, Sadoshima J, Shioi T, Izumo S, Lukoshkova EV, Dart AM, Jennings GL, McMullen JR.

Am J Pathol. 2009 Sep;175(3):998-1009. doi: 10.2353/ajpath.2009.090126. Epub 2009 Aug 13.

32.

Wnt3a-induced mesoderm formation and cardiomyogenesis in human embryonic stem cells.

Tran TH, Wang X, Browne C, Zhang Y, Schinke M, Izumo S, Burcin M.

Stem Cells. 2009 Aug;27(8):1869-78. doi: 10.1002/stem.95.

33.

CD8 positive T-cell infiltration in the dentate nucleus of paraneoplastic cerebellar degeneration.

Aye MM, Kasai T, Tashiro Y, Xing HQ, Shirahama H, Mitsuda M, Suetsugu T, Tanaka K, Osame M, Izumo S.

J Neuroimmunol. 2009 Mar 31;208(1-2):136-40. doi: 10.1016/j.jneuroim.2009.01.017. Epub 2009 Feb 13.

PMID:
19217169
34.

In vivo expression of proinflammatory cytokines in HIV encephalitis: an analysis of 11 autopsy cases.

Xing HQ, Hayakawa H, Izumo K, Kubota R, Gelpi E, Budka H, Izumo S.

Neuropathology. 2009 Aug;29(4):433-42. doi: 10.1111/j.1440-1789.2008.00996.x. Epub 2009 Jan 9.

PMID:
19170891
35.

Reduced expression of excitatory amino acid transporter 2 and diffuse microglial activation in the cerebral cortex in AIDS cases with or without HIV encephalitis.

Xing HQ, Hayakawa H, Gelpi E, Kubota R, Budka H, Izumo S.

J Neuropathol Exp Neurol. 2009 Feb;68(2):199-209. doi: 10.1097/NEN.0b013e31819715df.

PMID:
19151621
36.

Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.

Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H566-72. doi: 10.1152/ajpheart.00562.2008. Epub 2009 Jan 2.

37.

Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy.

Hayashi D, Kubota R, Takenouchi N, Nakamura T, Umehara F, Arimura K, Izumo S, Osame M.

J Neurovirol. 2008 Oct;14(5):459-63. doi: 10.1080/13550280802178538. Epub 2008 Nov 12.

PMID:
18989817
38.

Phosphatidylinositol 3-kinase gamma is a critical mediator of myocardial ischemic and adenosine-mediated preconditioning.

Ban K, Cooper AJ, Samuel S, Bhatti A, Patel M, Izumo S, Penninger JM, Backx PH, Oudit GY, Tsushima RG.

Circ Res. 2008 Sep 12;103(6):643-53. doi: 10.1161/CIRCRESAHA.108.175018. Epub 2008 Aug 7.

PMID:
18688045
39.

Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy.

Hayashi D, Kubota R, Takenouchi N, Tanaka Y, Hirano R, Takashima H, Osame M, Izumo S, Arimura K.

J Neuroimmunol. 2008 Aug 30;200(1-2):115-24. doi: 10.1016/j.jneuroim.2008.06.005. Epub 2008 Jul 18.

PMID:
18639344
40.

Impaired astrocytes and diffuse activation of microglia in the cerebral cortex in simian immunodeficiency virus-infected Macaques without simian immunodeficiency virus encephalitis.

Xing HQ, Mori K, Sugimoto C, Ono F, Izumo K, Kuboda R, Izumo S.

J Neuropathol Exp Neurol. 2008 Jun;67(6):600-11. doi: 10.1097/NEN.0b013e3181772ce0.

PMID:
18520778
41.

Expression of proinflammatory cytokines and its relationship with virus infection in the brain of macaques inoculated with macrophage-tropic simian immunodeficiency virus.

Xing HQ, Moritoyo T, Mori K, Sugimoto C, Ono F, Izumo S.

Neuropathology. 2009 Feb;29(1):13-9. doi: 10.1111/j.1440-1789.2008.00929.x. Epub 2008 May 27.

PMID:
18507770
42.

Impaired function of human T-lymphotropic virus type 1 (HTLV-1)-specific CD8+ T cells in HTLV-1-associated neurologic disease.

Sabouri AH, Usuku K, Hayashi D, Izumo S, Ohara Y, Osame M, Saito M.

Blood. 2008 Sep 15;112(6):2411-20. doi: 10.1182/blood-2008-02-140335. Epub 2008 May 23.

PMID:
18502825
43.

Significantly increased antibody response to heterogeneous nuclear ribonucleoproteins in cerebrospinal fluid of multiple sclerosis patients but not in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.

Yukitake M, Sueoka E, Sueoka-Aragane N, Sato A, Ohashi H, Yakushiji Y, Saito M, Osame M, Izumo S, Kuroda Y.

J Neurovirol. 2008 Apr;14(2):130-5. doi: 10.1080/13550280701883840.

PMID:
18444084
44.

Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism.

Ha T, Hua F, Liu X, Ma J, McMullen JR, Shioi T, Izumo S, Kelley J, Gao X, Browder W, Williams DL, Kao RL, Li C.

Cardiovasc Res. 2008 Jun 1;78(3):546-53. doi: 10.1093/cvr/cvn037. Epub 2008 Feb 11.

PMID:
18267957
45.

Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide.

Nose H, Kubota R, Seth NP, Goon PK, Tanaka Y, Izumo S, Usuku K, Ohara Y, Wucherpfennig KW, Bangham CR, Osame M, Saito M.

J Infect Dis. 2007 Dec 15;196(12):1761-72. doi: 10.1086/522966.

46.

Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.

Matsuura E, Umehara F, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.

J Neuropathol Exp Neurol. 2008 Jan;67(1):41-9.

PMID:
18091562
47.

Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF.

EMBO J. 2007 Nov 14;26(22):4732-43. Epub 2007 Oct 18.

48.

A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED.

Cell Metab. 2007 Oct;6(4):294-306.

49.

Resistin, an adipocytokine, offers protection against acute myocardial infarction.

Gao J, Chang Chua C, Chen Z, Wang H, Xu X, C Hamdy R, McMullen JR, Shioi T, Izumo S, Chua BH.

J Mol Cell Cardiol. 2007 Nov;43(5):601-9. Epub 2007 Aug 22.

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