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Items: 1 to 50 of 265

1.

Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.

Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.

EBioMedicine. 2019 Jul;45:362-378. doi: 10.1016/j.ebiom.2019.06.013. Epub 2019 Jun 29.

2.

The updated retrospective questionnaire study of sporadic inclusion body myositis in Japan.

Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Mori M, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Ito H, Higuchi I, Hashiguchi A, Nodera H, Kaji R, Tateyama M, Izumi R, Ono H, Kato M, Warita H, Takahashi T, Nishino I, Aoki M.

Orphanet J Rare Dis. 2019 Jun 26;14(1):155. doi: 10.1186/s13023-019-1122-5.

3.

Acalabrutinib monotherapy in patients with chronic lymphocytic leukemia who are intolerant to ibrutinib.

Awan FT, Schuh A, Brown JR, Furman RR, Pagel JM, Hillmen P, Stephens DM, Woyach J, Bibikova E, Charuworn P, Frigault MM, Hamdy A, Izumi R, Linghu B, Patel P, Wang MH, Byrd JC.

Blood Adv. 2019 May 14;3(9):1553-1562. doi: 10.1182/bloodadvances.2018030007.

4.

Interstitial pneumonia and other adverse events in riluzole-administered amyotrophic lateral sclerosis patients: a retrospective observational study.

Inoue-Shibui A, Kato M, Suzuki N, Kobayashi J, Takai Y, Izumi R, Kawauchi Y, Kuroda H, Warita H, Aoki M.

BMC Neurol. 2019 Apr 27;19(1):72. doi: 10.1186/s12883-019-1299-1.

5.

FDG-PET detects extensive calcinosis cutis in anti-NXP2 antibody-positive dermatomyositis.

Nakamura N, Izumi R, Hoshi Y, Takai Y, Ono R, Suzuki N, Nagai T, Ishii Y, Ishii T, Harigae H, Okada S, Aiba S, Okiyama N, Fujimoto M, Kuroda H, Tateyama M, Aoki M.

Rheumatology (Oxford). 2019 Mar 16. pii: kez083. doi: 10.1093/rheumatology/kez083. [Epub ahead of print] No abstract available.

PMID:
30879053
6.

[A Case of Type 4 Gastric Cancer with Esophageal Invasion That Responded to Neoadjuvant Chemotherapy Containing S-1 and Oxaliplatin followed by Surgery].

Hagino S, Fujimura T, Kurata T, Shoji Y, Sasaki S, Terada I, Yoshikawa A, Kitagawa H, Izumi R, Saito K.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2327-2329. Japanese.

PMID:
30692453
7.

Extranodal NK/T-cell Lymphoma Mimicking Granulomatous Myositis.

Kawaguchi N, Izumi R, Kobayashi M, Tateyama M, Suzuki N, Fujishima F, Fujimori J, Aoki M, Nakashima I.

Intern Med. 2019 Jan 15;58(2):277-282. doi: 10.2169/internalmedicine.0859-18. Epub 2018 Aug 24.

8.

CRISPR/Cas9-mediated Angptl8 knockout suppresses plasma triglyceride concentrations and adiposity in rats.

Izumi R, Kusakabe T, Noguchi M, Iwakura H, Tanaka T, Miyazawa T, Aotani D, Hosoda K, Kangawa K, Nakao K.

J Lipid Res. 2018 Sep;59(9):1575-1585. doi: 10.1194/jlr.M082099. Epub 2018 Jul 24.

PMID:
30042156
9.

Antagonizing bone morphogenetic protein 4 attenuates disease progression in a rat model of amyotrophic lateral sclerosis.

Shijo T, Warita H, Suzuki N, Ikeda K, Mitsuzawa S, Akiyama T, Ono H, Nishiyama A, Izumi R, Kitajima Y, Aoki M.

Exp Neurol. 2018 Sep;307:164-179. doi: 10.1016/j.expneurol.2018.06.009. Epub 2018 Jun 20.

PMID:
29932880
10.

TARDBP p.G376D mutation, found in rapid progressive familial ALS, induces mislocalization of TDP-43.

Mitsuzawa S, Akiyama T, Nishiyama A, Suzuki N, Kato M, Warita H, Izumi R, Osana S, Koyama S, Kato T, Suzuki Y, Aoki M.

eNeurologicalSci. 2018 Apr 12;11:20-22. doi: 10.1016/j.ensci.2018.04.001. eCollection 2018 Jun. No abstract available.

11.

Retraction: Azuma, K. et al. Chitin, Chitosan, and Its Derivatives for Wound Healing: Old and New Materials. J. Funct. Biomater. 2015, 6, 104⁻142.

Azuma K, Izumi R, Osaki T, Ifuku S, Morimoto M, Saimoto H, Minami S, Okamoto Y; Journal of Functional Biomaterials Editorial Office.

J Funct Biomater. 2018 Jun 7;9(2). pii: E38. doi: 10.3390/jfb9020038.

12.

Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.

Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K.

Cell Rep. 2018 Jan 9;22(2):482-496. doi: 10.1016/j.celrep.2017.12.051.

13.

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.

Wang M, Rule S, Zinzani PL, Goy A, Casasnovas O, Smith SD, Damaj G, Doorduijn J, Lamy T, Morschhauser F, Panizo C, Shah B, Davies A, Eek R, Dupuis J, Jacobsen E, Kater AP, Le Gouill S, Oberic L, Robak T, Covey T, Dua R, Hamdy A, Huang X, Izumi R, Patel P, Rothbaum W, Slatter JG, Jurczak W.

Lancet. 2018 Feb 17;391(10121):659-667. doi: 10.1016/S0140-6736(17)33108-2. Epub 2017 Dec 11.

PMID:
29241979
14.

Focal Segmental Glomerulosclerosis Associated with Chronic Progressive External Ophthalmoplegia and Mitochondrial DNA A3243G Mutation.

Narumi K, Mishima E, Akiyama Y, Matsuhashi T, Nakamichi T, Kisu K, Nishiyama S, Ikenouchi H, Kikuchi A, Izumi R, Miyazaki M, Abe T, Sato H, Ito S.

Nephron. 2018;138(3):243-248. doi: 10.1159/000485109. Epub 2017 Nov 30.

PMID:
29190634
15.

Five-year history of dysphagia as a sole initial symptom in inclusion body myositis.

Shibata S, Izumi R, Hara T, Ohshima R, Nakamura N, Suzuki N, Kato K, Katori Y, Tateyama M, Kuroda H, Aoki M.

J Neurol Sci. 2017 Oct 15;381:325-327. doi: 10.1016/j.jns.2017.09.014. Epub 2017 Sep 12. No abstract available.

PMID:
28991709
16.

Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile.

Barf T, Covey T, Izumi R, van de Kar B, Gulrajani M, van Lith B, van Hoek M, de Zwart E, Mittag D, Demont D, Verkaik S, Krantz F, Pearson PG, Ulrich R, Kaptein A.

J Pharmacol Exp Ther. 2017 Nov;363(2):240-252. doi: 10.1124/jpet.117.242909. Epub 2017 Sep 7.

PMID:
28882879
17.

Aberrant astrocytic expression of chondroitin sulfate proteoglycan receptors in a rat model of amyotrophic lateral sclerosis.

Shijo T, Warita H, Suzuki N, Kitajima Y, Ikeda K, Akiyama T, Ono H, Mitsuzawa S, Nishiyama A, Izumi R, Aoki M.

J Neurosci Res. 2018 Feb;96(2):222-233. doi: 10.1002/jnr.24127. Epub 2017 Jul 28.

PMID:
28752900
18.

Development of ghrelin transgenic mice for elucidation of clinical implication of ghrelin.

Aotani D, Ariyasu H, Shimazu-Kuwahara S, Shimizu Y, Nomura H, Murofushi Y, Kaneko K, Izumi R, Matsubara M, Kanda H, Noguchi M, Tanaka T, Kusakabe T, Miyazawa T, Nakao K.

Endocr J. 2017;64(Suppl.):S31-S33. doi: 10.1507/endocrj.64.S31. Review.

19.

Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.

Niemann CU, Mora-Jensen HI, Dadashian EL, Krantz F, Covey T, Chen SS, Chiorazzi N, Izumi R, Ulrich R, Lannutti BJ, Wiestner A, Herman SEM.

Clin Cancer Res. 2017 Oct 1;23(19):5814-5823. doi: 10.1158/1078-0432.CCR-17-0650. Epub 2017 Jun 23.

20.

Efficacy of an emollient containing diethylene glycol/dilinoleic acid copolymer for the treatment of dry skin and pruritus in patients with senile xerosis.

Izumi R, Negi O, Suzuki T, Tominaga M, Kamo A, Suga Y, Matsukuma S, Takamori K.

J Cosmet Dermatol. 2017 Dec;16(4):e37-e41. doi: 10.1111/jocd.12332. Epub 2017 Mar 30.

PMID:
28371078
21.

Nationwide survey of Baller‑Gerold syndrome in Japanese population.

Kaneko H, Izumi R, Oda H, Ohara O, Sameshima K, Ohnishi H, Fukao T, Funato M.

Mol Med Rep. 2017 May;15(5):3222-3224. doi: 10.3892/mmr.2017.6408. Epub 2017 Mar 28.

PMID:
28358413
22.

[Therapeutic development for GNE myopathy.]

Suzuki N, Izumi R, Kato M, Warita H, Aoki M.

Clin Calcium. 2017;27(3):429-434. doi: CliCa1703429434. Japanese.

PMID:
28232658
23.

Cost effectiveness of the occupation-based approach for subacute stroke patients: result of a randomized controlled trial.

Nagayama H, Tomori K, Ohno K, Takahashi K, Nagatani R, Izumi R, Moriwaki K, Yamauchi K.

Top Stroke Rehabil. 2017 Jul;24(5):337-344. doi: 10.1080/10749357.2017.1289686. Epub 2017 Feb 15.

PMID:
28198661
24.

Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis.

Nishiyama A, Niihori T, Warita H, Izumi R, Akiyama T, Kato M, Suzuki N, Aoki Y, Aoki M.

Neurobiol Aging. 2017 May;53:194.e1-194.e8. doi: 10.1016/j.neurobiolaging.2017.01.004. Epub 2017 Jan 10.

PMID:
28160950
25.

[A Case of Gastrointestinal Stromal Tumor(GIST)Originating in the Anal Canal].

Terada I, Yoshikawa A, Maruzen S, Yagi Y, Sasaki S, Fukushima W, Kitagawa H, Fujimura T, Izumi R.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2453-2455. Japanese.

PMID:
28133352
26.

Sporadic Inclusion Body Myositis Manifesting as Isolated Muscle Weakness of the Finger Flexors Three Years after Disease Onset.

Suwa Y, Suzuki N, Soga T, Harada R, Shibui A, Kuroda H, Izumi R, Tateyama M, Nakashima I, Sonoo M, Aoki M.

Intern Med. 2016;55(23):3521-3524. Epub 2016 Dec 1.

27.

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia.

Herman SEM, Montraveta A, Niemann CU, Mora-Jensen H, Gulrajani M, Krantz F, Mantel R, Smith LL, McClanahan F, Harrington BK, Colomer D, Covey T, Byrd JC, Izumi R, Kaptein A, Ulrich R, Johnson AJ, Lannutti BJ, Wiestner A, Woyach JA.

Clin Cancer Res. 2017 Jun 1;23(11):2831-2841. doi: 10.1158/1078-0432.CCR-16-0463. Epub 2016 Nov 30.

28.

Multicenter questionnaire survey for sporadic inclusion body myositis in Japan.

Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Higuchi I, Kaji R, Tateyama M, Izumi R, Ono H, Kato M, Warita H, Takahashi T, Nishino I, Aoki M.

Orphanet J Rare Dis. 2016 Nov 8;11(1):146.

29.

Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether β-cyclodextrin gel in wound dressing applications.

Tabuchi R, Azuma K, Izumi R, Tanou T, Okamoto Y, Nagae T, Iohara D, Uekama K, Otagiri M, Hirayama F, Ifuku S, Anraku M.

Int J Pharm. 2016 Sep 25;511(2):1080-7. doi: 10.1016/j.ijpharm.2016.08.019. Epub 2016 Aug 10.

PMID:
27521704
30.

Age-Dependent Morphologic Alterations in the Outer Retinal and Choroidal Thicknesses Using Swept Source Optical Coherence Tomography.

Maruko I, Arakawa H, Koizumi H, Izumi R, Sunagawa H, Iida T.

PLoS One. 2016 Jul 28;11(7):e0159439. doi: 10.1371/journal.pone.0159439. eCollection 2016.

31.

Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma.

Harrington BK, Gardner HL, Izumi R, Hamdy A, Rothbaum W, Coombes KR, Covey T, Kaptein A, Gulrajani M, Van Lith B, Krejsa C, Coss CC, Russell DS, Zhang X, Urie BK, London CA, Byrd JC, Johnson AJ, Kisseberth WC.

PLoS One. 2016 Jul 19;11(7):e0159607. doi: 10.1371/journal.pone.0159607. eCollection 2016.

32.

[A Study of Patients with Regional Lymph Node Recurrence after Breast Surgery].

Fukushima W, Maruzen S, Yagi Y, Sasaki S, Terada I, Yoshikawa A, Kitagawa H, Fujimura T, Izumi R, Saito K.

Gan To Kagaku Ryoho. 2016 Jul;43(7):879-83. Japanese.

PMID:
27431633
33.

Chitin nanofibrils suppress skin inflammation in atopic dermatitis-like skin lesions in NC/Nga mice.

Izumi R, Azuma K, Izawa H, Morimoto M, Nagashima M, Osaki T, Tsuka T, Imagawa T, Ito N, Okamoto Y, Saimoto H, Ifuku S.

Carbohydr Polym. 2016 Aug 1;146:320-7. doi: 10.1016/j.carbpol.2016.03.068. Epub 2016 Mar 25.

PMID:
27112880
34.

Genetic profile for suspected dysferlinopathy identified by targeted next-generation sequencing.

Izumi R, Niihori T, Takahashi T, Suzuki N, Tateyama M, Watanabe C, Sugie K, Nakanishi H, Sobue G, Kato M, Warita H, Aoki Y, Aoki M.

Neurol Genet. 2015 Dec 10;1(4):e36. doi: 10.1212/NXG.0000000000000036. eCollection 2015 Dec.

35.

Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.

Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.

Neurol Genet. 2015 Sep 24;1(3):e23. doi: 10.1212/NXG.0000000000000023. eCollection 2015 Oct.

36.

Galectin-7 in the stratum corneum: a biomarker of the skin barrier function.

Niiyama S, Yoshino T, Yasuda C, Yu X, Izumi R, Ishiwatari S, Matsukuma S, Mukai H.

Int J Cosmet Sci. 2016 Oct;38(5):487-95. doi: 10.1111/ics.12326. Epub 2016 May 27.

PMID:
27028525
37.

Genotype-phenotype relationships in familial amyotrophic lateral sclerosis with FUS/TLS mutations in Japan.

Akiyama T, Warita H, Kato M, Nishiyama A, Izumi R, Ikeda C, Kamada M, Suzuki N, Aoki M.

Muscle Nerve. 2016 Sep;54(3):398-404. doi: 10.1002/mus.25061. Epub 2016 Feb 23.

PMID:
26823199
38.

Metastatic gastric carcinoma from breast cancer mimicking primary linitis plastica: A case report.

Yagi Y, Sasaki S, Yoshikawa A, Tsukioka Y, Fukushima W, Fujimura T, Hirosawa H, Izumi R, Saito K.

Oncol Lett. 2015 Dec;10(6):3483-3487. Epub 2015 Oct 9.

39.

Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.

Byrd JC, Harrington B, O'Brien S, Jones JA, Schuh A, Devereux S, Chaves J, Wierda WG, Awan FT, Brown JR, Hillmen P, Stephens DM, Ghia P, Barrientos JC, Pagel JM, Woyach J, Johnson D, Huang J, Wang X, Kaptein A, Lannutti BJ, Covey T, Fardis M, McGreivy J, Hamdy A, Rothbaum W, Izumi R, Diacovo TG, Johnson AJ, Furman RR.

N Engl J Med. 2016 Jan 28;374(4):323-32. doi: 10.1056/NEJMoa1509981. Epub 2015 Dec 7.

40.

Massive pneumoretroperitoneum arising from emphysematous cholecystitis: a case report and the literature review.

Yagi Y, Sasaki S, Terada I, Yoshikawa A, Fukushima W, Kitagawa H, Fujimura T, Izumi R, Saito K.

BMC Gastroenterol. 2015 Sep 8;15:114. doi: 10.1186/s12876-015-0345-8. Review.

41.

Effects of Oral Administration of Chitin Nanofiber on Plasma Metabolites and Gut Microorganisms.

Azuma K, Izumi R, Kawata M, Nagae T, Osaki T, Murahata Y, Tsuka T, Imagawa T, Ito N, Okamoto Y, Morimoto M, Izawa H, Saimoto H, Ifuku S.

Int J Mol Sci. 2015 Sep 10;16(9):21931-49. doi: 10.3390/ijms160921931.

42.

Favorable effects of superficially deacetylated chitin nanofibrils on the wound healing process.

Izumi R, Komada S, Ochi K, Karasawa L, Osaki T, Murahata Y, Tsuka T, Imagawa T, Itoh N, Okamoto Y, Izawa H, Morimoto M, Saimoto H, Azuma K, Ifuku S.

Carbohydr Polym. 2015 Jun 5;123:461-7. doi: 10.1016/j.carbpol.2015.02.005. Epub 2015 Feb 12.

PMID:
25843880
43.

Chitin, chitosan, and its derivatives for wound healing: old and new materials.

Azuma K, Izumi R, Osaki T, Ifuku S, Morimoto M, Saimoto H, Minami S, Okamoto Y.

J Funct Biomater. 2015 Mar 13;6(1):104-42. doi: 10.3390/jfb6010104. Review. Retraction in: J Funct Biomater. 2018 Jun 07;9(2):.

44.

Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway.

Funakoshi-Tago M, Okamoto K, Izumi R, Tago K, Yanagisawa K, Narukawa Y, Kiuchi F, Kasahara T, Tamura H.

Int Immunopharmacol. 2015 Mar;25(1):189-98. doi: 10.1016/j.intimp.2015.01.012. Epub 2015 Jan 19.

PMID:
25614224
45.

Proteasome dysfunction induces muscle growth defects and protein aggregation.

Kitajima Y, Tashiro Y, Suzuki N, Warita H, Kato M, Tateyama M, Ando R, Izumi R, Yamazaki M, Abe M, Sakimura K, Ito H, Urushitani M, Nagatomi R, Takahashi R, Aoki M.

J Cell Sci. 2014 Dec 15;127(Pt 24):5204-17. doi: 10.1242/jcs.150961. Epub 2014 Nov 6.

46.

Long-Term Grading of Health-Related Quality of Life of Care-Needed Elderly: A 2-Yr Follow-Up Study.

Noto S, Izumi R, Moriwaki K.

Value Health. 2014 Nov;17(7):A514. doi: 10.1016/j.jval.2014.08.1587. Epub 2014 Oct 26. No abstract available.

47.

A Comparison of Value for Health States Worse Than Dead Between Japan and Uk.

Noto S, Shimozuma K, Saito S, Shiroiwa T, Fukuda T, Moriwaki K, Izumi R.

Value Health. 2014 Nov;17(7):A514. doi: 10.1016/j.jval.2014.08.1585. Epub 2014 Oct 26. No abstract available.

48.

Cost-Effectiveness of Multiple Anti-Osteoporotic Therapies for Secondary Fracture Prevention in Japan.

Moriwaki K, Yoshimura M, Izumi R, Noto S.

Value Health. 2014 Nov;17(7):A381. doi: 10.1016/j.jval.2014.08.2620. Epub 2014 Oct 26. No abstract available.

49.

GNE myopathy associated with congenital thrombocytopenia: a report of two siblings.

Izumi R, Niihori T, Suzuki N, Sasahara Y, Rikiishi T, Nishiyama A, Nishiyama S, Endo K, Kato M, Warita H, Konno H, Takahashi T, Tateyama M, Nagashima T, Funayama R, Nakayama K, Kure S, Matsubara Y, Aoki Y, Aoki M.

Neuromuscul Disord. 2014 Dec;24(12):1068-72. doi: 10.1016/j.nmd.2014.07.008. Epub 2014 Aug 8.

PMID:
25257349
50.

Modeling absolute lymphocyte counts after treatment of chronic lymphocytic leukemia with ibrutinib.

Smith DD, Goldstein L, Cheng M, James DF, Kunkel LA, Fardis M, Hamdy A, Izumi R, Buggy JJ, Clow F.

Ann Hematol. 2015 Feb;94(2):249-56. doi: 10.1007/s00277-014-2187-9. Epub 2014 Sep 3.

PMID:
25178517

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