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Items: 26

1.

Influenza A: New Therapeutic Targets for a Deadly Disease.

Manzano D, Izquierdo-Garcia JL, Martín-Loeches I, Lorente JA.

Arch Bronconeumol. 2018 Nov 5. pii: S0300-2896(18)30354-5. doi: 10.1016/j.arbres.2018.09.020. [Epub ahead of print] English, Spanish. No abstract available.

2.

Identification of novel metabolomic biomarkers in an experimental model of septic acute kidney injury.

Izquierdo-Garcia JL, Nin N, Cardinal-Fernandez P, Rojas Y, de Paula M, Granados R, Martínez-Caro L, Ruíz-Cabello J, Lorente JA.

Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F54-F62. doi: 10.1152/ajprenal.00315.2018. Epub 2018 Oct 31.

PMID:
30379100
3.

Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension.

Izquierdo-Garcia JL, Arias T, Rojas Y, Garcia-Ruiz V, Santos A, Martin-Puig S, Ruiz-Cabello J.

Front Cardiovasc Med. 2018 Aug 15;5:110. doi: 10.3389/fcvm.2018.00110. eCollection 2018.

4.

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome.

Callejo M, Mondejar-Parreño G, Barreira B, Izquierdo-Garcia JL, Morales-Cano D, Esquivel-Ruiz S, Moreno L, Cogolludo Á, Duarte J, Perez-Vizcaino F.

Sci Rep. 2018 Jun 26;8(1):9681. doi: 10.1038/s41598-018-27682-w.

5.

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM.

Cancer Metab. 2018 Apr 3;6:3. doi: 10.1186/s40170-018-0178-3. eCollection 2018.

6.

2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas.

Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM.

Cancer Res. 2018 May 1;78(9):2290-2304. doi: 10.1158/0008-5472.CAN-17-2926. Epub 2018 Jan 22.

PMID:
29358170
7.

Metabolomic Profile of ARDS by Nuclear Magnetic Resonance Spectroscopy in Patients With H1N1 Influenza Virus Pneumonia.

Izquierdo-Garcia JL, Nin N, Jimenez-Clemente J, Horcajada JP, Arenas-Miras MDM, Gea J, Esteban A, Ruiz-Cabello J, Lorente JA.

Shock. 2018 Nov;50(5):504-510. doi: 10.1097/SHK.0000000000001099.

PMID:
29293175
8.

The future of metabolomics in ELIXIR.

van Rijswijk M, Beirnaert C, Caron C, Cascante M, Dominguez V, Dunn WB, Ebbels TMD, Giacomoni F, Gonzalez-Beltran A, Hankemeier T, Haug K, Izquierdo-Garcia JL, Jimenez RC, Jourdan F, Kale N, Klapa MI, Kohlbacher O, Koort K, Kultima K, Le Corguillé G, Moreno P, Moschonas NK, Neumann S, O'Donovan C, Reczko M, Rocca-Serra P, Rosato A, Salek RM, Sansone SA, Satagopam V, Schober D, Shimmo R, Spicer RA, Spjuth O, Thévenot EA, Viant MR, Weber RJM, Willighagen EL, Zanetti G, Steinbeck C.

Version 2. F1000Res. 2017 Sep 6 [revised 2017 Jan 1];6. pii: ELIXIR-1649. doi: 10.12688/f1000research.12342.2. eCollection 2017.

9.

Brain Tumor Imaging.

Brindle KM, Izquierdo-García JL, Lewis DY, Mair RJ, Wright AJ.

J Clin Oncol. 2017 Jul 20;35(21):2432-2438. doi: 10.1200/JCO.2017.72.7636. Epub 2017 Jun 22. Review.

PMID:
28640699
10.

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.

Menendez-Montes I, Escobar B, Palacios B, Gómez MJ, Izquierdo-Garcia JL, Flores L, Jiménez-Borreguero LJ, Aragones J, Ruiz-Cabello J, Torres M, Martin-Puig S.

Dev Cell. 2016 Dec 19;39(6):724-739. doi: 10.1016/j.devcel.2016.11.012.

11.

New Biochemical Insights into the Mechanisms of Pulmonary Arterial Hypertension in Humans.

Bujak R, Mateo J, Blanco I, Izquierdo-García JL, Dudzik D, Markuszewski MJ, Peinado VI, Laclaustra M, Barberá JA, Barbas C, Ruiz-Cabello J.

PLoS One. 2016 Aug 3;11(8):e0160505. doi: 10.1371/journal.pone.0160505. eCollection 2016.

12.

Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters.

Viswanath P, Najac C, Izquierdo-Garcia JL, Pankov A, Hong C, Eriksson P, Costello JF, Pieper RO, Ronen SM.

Oncotarget. 2016 Jun 7;7(23):34942-55. doi: 10.18632/oncotarget.9006.

13.

IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.

Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM.

Cancer Res. 2015 Aug 1;75(15):2999-3009. doi: 10.1158/0008-5472.CAN-15-0840. Epub 2015 Jun 4.

14.

Metabolic reprogramming in mutant IDH1 glioma cells.

Izquierdo-Garcia JL, Viswanath P, Eriksson P, Chaumeil MM, Pieper RO, Phillips JJ, Ronen SM.

PLoS One. 2015 Feb 23;10(2):e0118781. doi: 10.1371/journal.pone.0118781. eCollection 2015.

15.

Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase.

Izquierdo-Garcia JL, Cai LM, Chaumeil MM, Eriksson P, Robinson AE, Pieper RO, Phillips JJ, Ronen SM.

PLoS One. 2014 Sep 22;9(9):e108289. doi: 10.1371/journal.pone.0108289. eCollection 2014.

16.

HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer.

Wang AS, Lodi A, Rivera LB, Izquierdo-Garcia JL, Firpo MA, Mulvihill SJ, Tempero MA, Bergers G, Ronen SM.

NMR Biomed. 2014 Nov;27(11):1361-70. doi: 10.1002/nbm.3198. Epub 2014 Sep 9.

17.

β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.

García-Prieto J, García-Ruiz JM, Sanz-Rosa D, Pun A, García-Alvarez A, Davidson SM, Fernández-Friera L, Nuno-Ayala M, Fernández-Jiménez R, Bernal JA, Izquierdo-Garcia JL, Jimenez-Borreguero J, Pizarro G, Ruiz-Cabello J, Macaya C, Fuster V, Yellon DM, Ibanez B.

Basic Res Cardiol. 2014 Jul;109(4):422. doi: 10.1007/s00395-014-0422-0. Epub 2014 Jun 21.

PMID:
24951958
18.

A Metabolomic Approach to the Pathogenesis of Ventilator-induced Lung Injury.

Izquierdo-García JL, Naz S, Nin N, Rojas Y, Erazo M, Martínez-Caro L, García A, de Paula M, Fernández-Segoviano P, Casals C, Esteban A, Ruíz-Cabello J, Barbas C, Lorente JA.

Anesthesiology. 2014 Mar;120(3):694-702. doi: 10.1097/ALN.0000000000000074.

PMID:
24253045
19.

HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells.

Ward CS, Eriksson P, Izquierdo-Garcia JL, Brandes AH, Ronen SM.

PLoS One. 2013 Apr 23;8(4):e62610. doi: 10.1371/journal.pone.0062610. Print 2013.

20.

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.

Luxán G, Casanova JC, Martínez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-García JL, Fernández-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibañez B, Medrano C, García-Pavía P, Gimeno JR, Monserrat L, Jiménez-Borreguero LJ, de la Pompa JL.

Nat Med. 2013 Feb;19(2):193-201. doi: 10.1038/nm.3046. Epub 2013 Jan 13.

PMID:
23314057
21.

Influence of ambient air on NMR-based metabolomics of exhaled breath condensates.

Izquierdo-García JL, Peces-Barba G, Ruiz-Cabello J.

Eur Respir J. 2012 Nov;40(5):1294-6. doi: 10.1183/09031936.00049012. No abstract available.

22.

Dynamic ventilation 3He MRI for the quantification of disease in the rat lung.

Kyriazis A, Rodriguez I, Nin N, Izquierdo-Garcia JL, Lorente JA, Perez-Sanchez JM, Pesic J, Olsson LE, Ruiz-Cabello J.

IEEE Trans Biomed Eng. 2012 Mar;59(3):777-86. doi: 10.1109/TBME.2011.2179299. Epub 2011 Dec 9.

PMID:
22167560
23.

A metabolomic approach for diagnosis of experimental sepsis.

Izquierdo-García JL, Nin N, Ruíz-Cabello J, Rojas Y, de Paula M, López-Cuenca S, Morales L, Martínez-Caro L, Fernández-Segoviano P, Esteban A, Lorente JA.

Intensive Care Med. 2011 Dec;37(12):2023-32. doi: 10.1007/s00134-011-2359-1. Epub 2011 Oct 6.

PMID:
21976186
24.

Descriptive review of current NMR-based metabolomic data analysis packages.

Izquierdo-García JL, Villa P, Kyriazis A, del Puerto-Nevado L, Pérez-Rial S, Rodriguez I, Hernandez N, Ruiz-Cabello J.

Prog Nucl Magn Reson Spectrosc. 2011 Oct;59(3):263-70. doi: 10.1016/j.pnmrs.2011.02.001. Epub 2011 Feb 21. Review. No abstract available.

PMID:
21920221
25.

Is NMR-based metabolomic analysis of exhaled breath condensate accurate?

Izquierdo-García JL, Peces-Barba G, Heili S, Diaz R, Want E, Ruiz-Cabello J.

Eur Respir J. 2011 Feb;37(2):468-70. doi: 10.1183/09031936.00094010. No abstract available.

26.

A novel R-package graphic user interface for the analysis of metabonomic profiles.

Izquierdo-García JL, Rodríguez I, Kyriazis A, Villa P, Barreiro P, Desco M, Ruiz-Cabello J.

BMC Bioinformatics. 2009 Oct 29;10:363. doi: 10.1186/1471-2105-10-363.

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