Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 352

1.

In vivo reprogramming of wound-resident cells generates skin epithelial tissue.

Kurita M, Araoka T, Hishida T, O'Keefe DD, Takahashi Y, Sakamoto A, Sakurai M, Suzuki K, Wu J, Yamamoto M, Hernandez-Benitez R, Ocampo A, Reddy P, Shokhirev MN, Magistretti P, Núñez Delicado E, Eto H, Harii K, Izpisua Belmonte JC.

Nature. 2018 Sep;561(7722):243-247. doi: 10.1038/s41586-018-0477-4. Epub 2018 Sep 5.

PMID:
30185909
2.

Forty years of IVF.

Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR.

Fertil Steril. 2018 Jul 15;110(2):185-324.e5. doi: 10.1016/j.fertnstert.2018.06.005. Review.

PMID:
30053940
3.

At the Heart of Genome Editing and Cardiovascular Diseases.

Hernandez-Benitez R, Martinez-Martinez ML, Lajara J, Magistretti P, Montserrat N, Izpisua Belmonte JC.

Circ Res. 2018 Jul 6;123(2):221-223. doi: 10.1161/CIRCRESAHA.118.312676. No abstract available.

PMID:
29976689
4.

Deconstructing the pluripotency gene regulatory network.

Li M, Izpisua Belmonte JC.

Nat Cell Biol. 2018 Apr;20(4):382-392. doi: 10.1038/s41556-018-0067-6. Epub 2018 Mar 28. Review.

PMID:
29593328
5.

Generation of two induced pluripotent stem cell (iPSC) lines from p.F508del Cystic Fibrosis patients.

Fleischer A, Lorenzo IM, Palomino E, Aasen T, Gómez F, Servera M, Asensio VJ, Gálvez V, Izpisúa-Belmonte JC, Bachiller D.

Stem Cell Res. 2018 May;29:1-5. doi: 10.1016/j.scr.2018.03.004. Epub 2018 Mar 11.

6.

Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts.

Bogliotti YS, Wu J, Vilarino M, Okamura D, Soto DA, Zhong C, Sakurai M, Sampaio RV, Suzuki K, Izpisua Belmonte JC, Ross PJ.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2090-2095. doi: 10.1073/pnas.1716161115. Epub 2018 Feb 9.

7.

Elixir of Life: Thwarting Aging With Regenerative Reprogramming.

Beyret E, Martinez Redondo P, Platero Luengo A, Izpisua Belmonte JC.

Circ Res. 2018 Jan 5;122(1):128-141. doi: 10.1161/CIRCRESAHA.117.311866. Review.

PMID:
29301845
8.

In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.

Liao HK, Hatanaka F, Araoka T, Reddy P, Wu MZ, Sui Y, Yamauchi T, Sakurai M, O'Keefe DD, Núñez-Delicado E, Guillen P, Campistol JM, Wu CJ, Lu LF, Esteban CR, Izpisua Belmonte JC.

Cell. 2017 Dec 14;171(7):1495-1507.e15. doi: 10.1016/j.cell.2017.10.025. Epub 2017 Dec 7.

PMID:
29224783
9.

In vivo genome editing via the HITI method as a tool for gene therapy.

Suzuki K, Izpisua Belmonte JC.

J Hum Genet. 2018 Feb;63(2):157-164. doi: 10.1038/s10038-017-0352-4. Epub 2017 Nov 13. Review.

PMID:
29215090
10.

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation.

Pei D, Beier DW, Levy-Lahad E, Marchant G, Rossant J, Izpisua Belmonte JC, Lovell-Badge R, Jaenisch R, Charo A, Baltimore D.

Cell Stem Cell. 2017 Oct 5;21(4):423-426. doi: 10.1016/j.stem.2017.09.010.

PMID:
28985523
11.

miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS.

Wu MZ, Cheng WC, Chen SF, Nieh S, O'Connor C, Liu CL, Tsai WW, Wu CJ, Martin L, Lin YS, Wu KJ, Lu LF, Izpisua Belmonte JC.

Nat Cell Biol. 2017 Oct;19(10):1286-1296. doi: 10.1038/ncb3615. Epub 2017 Sep 18.

12.

Regulation of Stem Cell Aging by Metabolism and Epigenetics.

Ren R, Ocampo A, Liu GH, Izpisua Belmonte JC.

Cell Metab. 2017 Sep 5;26(3):460-474. doi: 10.1016/j.cmet.2017.07.019. Epub 2017 Aug 17. Review.

13.

Keeping the Rhythm while Changing the Lyrics: Circadian Biology in Aging.

Hatanaka F, Ocampo A, Izpisua Belmonte JC.

Cell. 2017 Aug 10;170(4):599-600. doi: 10.1016/j.cell.2017.07.039.

14.

Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding.

Yang J, Li J, Suzuki K, Liu X, Wu J, Zhang W, Ren R, Zhang W, Chan P, Izpisua Belmonte JC, Qu J, Tang F, Liu GH.

Cell Res. 2017 Sep;27(9):1178-1181. doi: 10.1038/cr.2017.86. Epub 2017 Jul 7. No abstract available.

15.

Gathering by the Red Sea highlights links between environment and epigenetics.

Li M, Borrelli E, Magistretti PJ, Izpisua Belmonte JC, Sassone-Corsi P, Orlando V.

Nat Struct Mol Biol. 2017 Jun 6;24(6):491-493. doi: 10.1038/nsmb.3422. No abstract available.

PMID:
28586330
16.

Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing.

Garreta E, Prado P, Izpisua Belmonte JC, Montserrat N.

Noncoding RNA Res. 2017 May 17;2(2):93-99. doi: 10.1016/j.ncrna.2017.05.001. eCollection 2017 Jun. Review.

17.

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.

Panopoulos AD, D'Antonio M, Benaglio P, Williams R, Hashem SI, Schuldt BM, DeBoever C, Arias AD, Garcia M, Nelson BC, Harismendy O, Jakubosky DA, Donovan MKR, Greenwald WW, Farnam K, Cook M, Borja V, Miller CA, Grinstein JD, Drees F, Okubo J, Diffenderfer KE, Hishida Y, Modesto V, Dargitz CT, Feiring R, Zhao C, Aguirre A, McGarry TJ, Matsui H, Li H, Reyna J, Rao F, O'Connor DT, Yeo GW, Evans SM, Chi NC, Jepsen K, Nariai N, Müller FJ, Goldstein LSB, Izpisua Belmonte JC, Adler E, Loring JF, Berggren WT, D'Antonio-Chronowska A, Smith EN, Frazer KA.

Stem Cell Reports. 2017 Apr 11;8(4):1086-1100. doi: 10.1016/j.stemcr.2017.03.012.

18.

Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics.

Panopoulos AD, Smith EN, Arias AD, Shepard PJ, Hishida Y, Modesto V, Diffenderfer KE, Conner C, Biggs W, Sandoval E, D'Antonio-Chronowska A, Berggren WT, Izpisua Belmonte JC, Frazer KA.

Cell Stem Cell. 2017 Apr 6;20(4):505-517.e6. doi: 10.1016/j.stem.2017.03.010.

19.

Interspecies Chimerism with Mammalian Pluripotent Stem Cells.

Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Morales Valencia M, Okumura D, Luo J, Vilariño M, Parrilla I, Soto DA, Martinez CA, Hishida T, Sánchez-Bautista S, Martinez-Martinez ML, Wang H, Nohalez A, Aizawa E, Martinez-Redondo P, Ocampo A, Reddy P, Roca J, Maga EA, Esteban CR, Berggren WT, Nuñez Delicado E, Lajara J, Guillen I, Guillen P, Campistol JM, Martinez EA, Ross PJ, Izpisua Belmonte JC.

Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036.

20.

Genome editing in human pluripotent stem cells: a systematic approach unrevealing pancreas development and disease.

Garreta E, Marco A, Izpisua Belmonte JC, Montserrat N.

Stem Cell Investig. 2016 Nov 14;3:76. doi: 10.21037/sci.2016.10.11. eCollection 2016. No abstract available.

21.

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.

Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Rodriguez Esteban C, Nuñez G, Nuñez Delicado E, Campistol JM, Guillen I, Guillen P, Izpisua Belmonte JC.

Cell. 2016 Dec 15;167(7):1719-1733.e12. doi: 10.1016/j.cell.2016.11.052.

22.

Human Organs from Animal Bodies.

Izpisúa Belmonte JC.

Sci Am. 2016 Oct 18;315(5):32-37. doi: 10.1038/scientificamerican1116-32. No abstract available.

PMID:
27918510
23.

Generation of human organs in pigs via interspecies blastocyst complementation.

Wu J, Platero Luengo A, Gil MA, Suzuki K, Cuello C, Morales Valencia M, Parrilla I, Martinez CA, Nohalez A, Roca J, Martinez EA, Izpisua Belmonte JC.

Reprod Domest Anim. 2016 Oct;51 Suppl 2:18-24. doi: 10.1111/rda.12796.

PMID:
27762052
24.

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors.

Li Z, Araoka T, Wu J, Liao HK, Li M, Lazo M, Zhou B, Sui Y, Wu MZ, Tamura I, Xia Y, Beyret E, Matsusaka T, Pastan I, Rodriguez Esteban C, Guillen I, Guillen P, Campistol JM, Izpisua Belmonte JC.

Cell Stem Cell. 2016 Oct 6;19(4):516-529. doi: 10.1016/j.stem.2016.07.016. Epub 2016 Aug 25.

25.

Looking to the future following 10 years of induced pluripotent stem cell technologies.

Li M, Izpisua Belmonte JC.

Nat Protoc. 2016 Sep;11(9):1579-85. doi: 10.1038/nprot.2016.108. Epub 2016 Aug 4. Review.

PMID:
27490631
26.

Stem Cells: A Renaissance in Human Biology Research.

Wu J, Izpisua Belmonte JC.

Cell. 2016 Jun 16;165(7):1572-1585. doi: 10.1016/j.cell.2016.05.043. Review.

27.

Reprogramming strategies for the establishment of novel human cancer models.

Sancho-Martinez I, Izpisua Belmonte JC.

Cell Cycle. 2016 Sep 16;15(18):2393-7. doi: 10.1080/15384101.2016.1196305. Epub 2016 Jun 17. Review.

28.

Characterization of the Epigenetic Changes During Human Gonadal Primordial Germ Cells Reprogramming.

Eguizabal C, Herrera L, De Oñate L, Montserrat N, Hajkova P, Izpisua Belmonte JC.

Stem Cells. 2016 Sep;34(9):2418-28. doi: 10.1002/stem.2422. Epub 2016 Jun 30.

29.

An overview of mammalian pluripotency.

Wu J, Yamauchi T, Izpisua Belmonte JC.

Development. 2016 May 15;143(10):1644-8. doi: 10.1242/dev.132928. Review.

30.

Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts.

Garreta E, de Oñate L, Fernández-Santos ME, Oria R, Tarantino C, Climent AM, Marco A, Samitier M, Martínez E, Valls-Margarit M, Matesanz R, Taylor DA, Fernández-Avilés F, Izpisua Belmonte JC, Montserrat N.

Biomaterials. 2016 Aug;98:64-78. doi: 10.1016/j.biomaterials.2016.04.003. Epub 2016 Apr 26.

31.

Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells.

Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, Nishimoto M, Nakachi Y, Mizuno Y, Okazaki Y, Matsui Y, Izpisua Belmonte JC, Okuda A.

Nat Commun. 2016 Mar 30;7:11056. doi: 10.1038/ncomms11056.

32.

Regenerative strategies for kidney engineering.

Montserrat N, Garreta E, Izpisua Belmonte JC.

FEBS J. 2016 Sep;283(18):3303-24. doi: 10.1111/febs.13704. Epub 2016 Mar 24. Review.

33.

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells.

Sancho-Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, Ma L, Morey R, Krause MN, Zembrzycki A, Ansorge O, Vazquez-Ferrer E, Dubova I, Reddy P, Lam D, Hishida Y, Wu MZ, Esteban CR, O'Leary D, Wahl GM, Verma IM, Laurent LC, Izpisua Belmonte JC.

Nat Commun. 2016 Feb 22;7:10743. doi: 10.1038/ncomms10743.

34.

Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs.

Fu L, Xu X, Ren R, Wu J, Zhang W, Yang J, Ren X, Wang S, Zhao Y, Sun L, Yu Y, Wang Z, Yang Z, Yuan Y, Qiao J, Izpisua Belmonte JC, Qu J, Liu GH.

Protein Cell. 2016 Mar;7(3):210-21. doi: 10.1007/s13238-016-0244-y. Epub 2016 Feb 13.

35.

Mending a Faltering Heart.

Li M, Izpisua Belmonte JC.

Circ Res. 2016 Jan 22;118(2):344-51. doi: 10.1161/CIRCRESAHA.115.306820. Review.

PMID:
26838318
36.

Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts.

Wu J, Izpisua Belmonte JC.

Transgenic Res. 2016 Jun;25(3):375-84. doi: 10.1007/s11248-016-9930-z. Epub 2016 Jan 28. Review.

PMID:
26820411
37.

The XEN of reprogramming.

Beyret E, Izpisua Belmonte JC.

Cell Res. 2016 Feb;26(2):147-8. doi: 10.1038/cr.2016.9. Epub 2016 Jan 22.

38.

Understanding the molecular mechanisms of reprogramming.

Krause MN, Sancho-Martinez I, Izpisua Belmonte JC.

Biochem Biophys Res Commun. 2016 May 6;473(3):693-7. doi: 10.1016/j.bbrc.2015.11.120. Epub 2015 Dec 2. Review.

PMID:
26655812
39.

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.

Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, Wu J, Xu X, Fu L, Li Y, Yang J, Zhang W, Bai R, Yi F, Suzuki K, Gao H, Esteban CR, Zhang C, Izpisua Belmonte JC, Chen Z, Wang X, Jiang T, Qu J, Tang F, Liu GH.

Nat Commun. 2015 Dec 3;6:10068. doi: 10.1038/ncomms10068.

40.

Metabolic exit from naive pluripotency.

Wu J, Izpisua Belmonte JC.

Nat Cell Biol. 2015 Dec;17(12):1519-21. doi: 10.1038/ncb3269.

PMID:
26612574
41.

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R.

Stem Cell Reports. 2015 Dec 8;5(6):933-945. doi: 10.1016/j.stemcr.2015.10.011. Epub 2015 Nov 21.

42.

Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes.

Jiménez G, López-Ruiz E, Kwiatkowski W, Montañez E, Arrebola F, Carrillo E, Gray PC, Izpisua Belmonte JC, Choe S, Perán M, Marchal JA.

Sci Rep. 2015 Nov 13;5:16400. doi: 10.1038/srep16400.

43.

Dynamic Pluripotent Stem Cell States and Their Applications.

Wu J, Izpisua Belmonte JC.

Cell Stem Cell. 2015 Nov 5;17(5):509-25. doi: 10.1016/j.stem.2015.10.009. Review.

44.

Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.

Wu MZ, Chen SF, Nieh S, Benner C, Ger LP, Jan CI, Ma L, Chen CH, Hishida T, Chang HT, Lin YS, Montserrat N, Gascon P, Sancho-Martinez I, Izpisua Belmonte JC.

Cancer Res. 2015 Sep 15;75(18):3912-24. doi: 10.1158/0008-5472.CAN-14-3208. Epub 2015 Aug 20.

45.

Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders.

Féron F, Gepner B, Lacassagne E, Stephan D, Mesnage B, Blanchard MP, Boulanger N, Tardif C, Devèze A, Rousseau S, Suzuki K, Izpisua Belmonte JC, Khrestchatisky M, Nivet E, Erard-Garcia M.

Mol Psychiatry. 2016 Sep;21(9):1215-24. doi: 10.1038/mp.2015.106. Epub 2015 Aug 4.

46.

Metabolic rescue in pluripotent cells from patients with mtDNA disease.

Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez NM, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, Wolf DP, Huang T, Terzic A, Laurent LC, Izpisua Belmonte JC, Mitalipov S.

Nature. 2015 Aug 13;524(7564):234-8. doi: 10.1038/nature14546. Epub 2015 Jul 15.

PMID:
26176921
47.

Stem cell, CRISPR and HIV.

Liao HK, Li M, Martinez Martinez L, Izpisua Belmonte JC.

Cell Cycle. 2015;14(13):1991-2. doi: 10.1080/15384101.2015.1046791. Epub 2015 Jun 3. No abstract available.

48.

Brains, genes, and primates.

Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J, Zhang F.

Neuron. 2015 May 6;86(3):617-31. doi: 10.1016/j.neuron.2015.03.021. Review. Erratum in: Neuron. 2015 Aug 5;87(3):671.

49.

An alternative pluripotent state confers interspecies chimaeric competency.

Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC.

Nature. 2015 May 21;521(7552):316-21. doi: 10.1038/nature14413. Epub 2015 May 6.

50.

Selective elimination of mitochondrial mutations in the germline by genome editing.

Reddy P, Ocampo A, Suzuki K, Luo J, Bacman SR, Williams SL, Sugawara A, Okamura D, Tsunekawa Y, Wu J, Lam D, Xiong X, Montserrat N, Esteban CR, Liu GH, Sancho-Martinez I, Manau D, Civico S, Cardellach F, Del Mar O'Callaghan M, Campistol J, Zhao H, Campistol JM, Moraes CT, Izpisua Belmonte JC.

Cell. 2015 Apr 23;161(3):459-469. doi: 10.1016/j.cell.2015.03.051.

Supplemental Content

Loading ...
Support Center