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Utility of wound cultures in the management of open globe injuries: a 5-year retrospective review.

Drumright RT, Regan KA, Lin AL, Moroux MG, Iyer SSR.

J Ophthalmic Inflamm Infect. 2020 Feb 3;10(1):5. doi: 10.1186/s12348-020-0196-5.


A role for glia maturation factor dependent activation of mast cells and microglia in MPTP induced dopamine loss and behavioural deficits in mice.

Selvakumar GP, Ahmed ME, Thangavel R, Kempuraj D, Dubova I, Raikwar SP, Zaheer S, Iyer SS, Zaheer A.

Brain Behav Immun. 2020 Jan 23. pii: S0889-1591(19)31218-8. doi: 10.1016/j.bbi.2020.01.013. [Epub ahead of print]


Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.

Verma A, Schmidt BA, Elizaldi SR, Nguyen NK, Walter KA, Beck Z, Trinh HV, Dinsarapu AR, Lakshmanappa YS, Rane NN, Matyas GR, Rao M, Shen X, Tomaras GD, LaBranche CC, Reimann KA, Foehl DH, Gach JS, Forthal DN, Kozlowski PA, Amara RR, Iyer SS.

J Virol. 2019 Dec 11. pii: JVI.01737-19. doi: 10.1128/JVI.01737-19. [Epub ahead of print]


Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques.

Elizaldi SR, Verma A, Walter KA, Rolston M, Dinasarapu AR, Durbin-Johnson BP, Settles M, Kozlowski PA, Raeman R, Iyer SS.

mSphere. 2019 Dec 11;4(6). pii: e00824-19. doi: 10.1128/mSphere.00824-19.


Fluorescent sialic derivatives for the specific detection of influenza viruses.

Liu D, Cui X, Dhawane AN, Chivukula V, Iyer SS.

Bioorg Med Chem Lett. 2019 Dec 15;29(24):126773. doi: 10.1016/j.bmcl.2019.126773. Epub 2019 Oct 31.


Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.

Bedard M, Shrestha D, Priestman DA, Wang Y, Schneider F, Matute JD, Iyer SS, Gileadi U, Prota G, Kandasamy M, Veerapen N, Besra G, Fritzsche M, Zeissig S, Shevchenko A, Christianson JC, Platt FM, Eggeling C, Blumberg RS, Salio M, Cerundolo V.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23671-23681. doi: 10.1073/pnas.1910097116. Epub 2019 Nov 5.


Exercise band-induced lens dislocations: A case series.

Rosignoli LM, Regan KA, Gray MJ, Ohning CR, Iyer SSR.

Am J Ophthalmol Case Rep. 2019 Jun 13;15:100496. doi: 10.1016/j.ajoc.2019.100496. eCollection 2019 Sep.


Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation.

Taechangam N, Iyer SS, Walker NJ, Arzi B, Borjesson DL.

Stem Cell Res Ther. 2019 Jun 25;10(1):188. doi: 10.1186/s13287-019-1300-3.


Dosimetric dependence of ocular structures on eye size and shape for external radiation fields of electrons, photons, and neutrons.

Furuta T, Basha DE, Iyer SSR, Alfonso CMC, Bolch WE.

J Radiol Prot. 2019 Sep;39(3):825-837. doi: 10.1088/1361-6498/ab2bcb. Epub 2019 Jun 21.


Highly accelerated multishot echo planar imaging through synergistic machine learning and joint reconstruction.

Bilgic B, Chatnuntawech I, Manhard MK, Tian Q, Liao C, Iyer SS, Cauley SF, Huang SY, Polimeni JR, Wald LL, Setsompop K.

Magn Reson Med. 2019 Oct;82(4):1343-1358. doi: 10.1002/mrm.27813. Epub 2019 May 20.


Brain Injury-Mediated Neuroinflammatory Response and Alzheimer's Disease.

Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Dhaliwal AS, Dubova I, Mentor S, Premkumar K, Saeed D, Zahoor H, Raikwar SP, Zaheer S, Iyer SS, Zaheer A.

Neuroscientist. 2019 May 16:1073858419848293. doi: 10.1177/1073858419848293. [Epub ahead of print]


Surgical management of diabetic tractional retinal detachments.

Iyer SSR, Regan KA, Burnham JM, Chen CJ.

Surv Ophthalmol. 2019 Nov - Dec;64(6):780-809. doi: 10.1016/j.survophthal.2019.04.008. Epub 2019 May 9. Review.


Next Generation Precision Medicine: CRISPR-mediated Genome Editing for the Treatment of Neurodegenerative Disorders.

Raikwar SP, Kikkeri NS, Sakuru R, Saeed D, Zahoor H, Premkumar K, Mentor S, Thangavel R, Dubova I, Ahmed ME, Selvakumar GP, Kempuraj D, Zaheer S, Iyer SS, Zaheer A.

J Neuroimmune Pharmacol. 2019 Dec;14(4):608-641. doi: 10.1007/s11481-019-09849-y. Epub 2019 Apr 23. Review.


SLAM-ing the brakes on iNKT cell selection.

Iyer SS, Huang YH, Blumberg RS.

Nat Immunol. 2019 Apr;20(4):378-379. doi: 10.1038/s41590-019-0355-8. No abstract available.


Mast Cells in Stress, Pain, Blood-Brain Barrier, Neuroinflammation and Alzheimer's Disease.

Kempuraj D, Mentor S, Thangavel R, Ahmed ME, Selvakumar GP, Raikwar SP, Dubova I, Zaheer S, Iyer SS, Zaheer A.

Front Cell Neurosci. 2019 Feb 19;13:54. doi: 10.3389/fncel.2019.00054. eCollection 2019.


The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise.

Lam KC, Chung HR, Semplicio G, Iyer SS, Gaub A, Bhardwaj V, Holz H, Georgiev P, Akhtar A.

Genes Dev. 2019 Apr 1;33(7-8):452-465. doi: 10.1101/gad.321489.118. Epub 2019 Feb 28.


Multiloculated Ciliary Body Cysts and Lenticular Coloboma: A Rare Phenotypic Variation Associated With Persistent Fetal Vasculature.

Gonzalez A, Agarwal-Sinha S, Iyer SSR, Bolling JP.

J Pediatr Ophthalmol Strabismus. 2018 Nov 2;55:e39-e41. doi: 10.3928/01913913-20181010-01.


Glia Maturation Factor and Mast Cell-Dependent Expression of Inflammatory Mediators and Proteinase Activated Receptor-2 in Neuroinflammation.

Kempuraj D, Selvakumar GP, Thangavel R, Ahmed ME, Zaheer S, Kumar KK, Yelam A, Kaur H, Dubova I, Raikwar SP, Iyer SS, Zaheer A.

J Alzheimers Dis. 2018;66(3):1117-1129. doi: 10.3233/JAD-180786.


Comparison of sampling methods for profiling cervicovaginal microbiome in rhesus macaques.

Schmidt BA, Phillips R, Rolston M, Raeman R, Iyer SS.

J Med Primatol. 2019 Feb;48(1):54-57. doi: 10.1111/jmp.12381. Epub 2018 Oct 2.


Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV.

Mylvaganam GH, Chea LS, Tharp GK, Hicks S, Velu V, Iyer SS, Deleage C, Estes JD, Bosinger SE, Freeman GJ, Ahmed R, Amara RR.

JCI Insight. 2018 Sep 20;3(18). pii: 122940. doi: 10.1172/jci.insight.122940. eCollection 2018 Sep 20.


Molecular Association of Glia Maturation Factor with the Autophagic Machinery in Rat Dopaminergic Neurons: a Role for Endoplasmic Reticulum Stress and MAPK Activation.

Selvakumar GP, Iyer SS, Kempuraj D, Ahmed ME, Thangavel R, Dubova I, Raikwar SP, Zaheer S, Zaheer A.

Mol Neurobiol. 2019 Jun;56(6):3865-3881. doi: 10.1007/s12035-018-1340-1. Epub 2018 Sep 14.


Detection of Enzymes, Viruses, and Bacteria Using Glucose Meters.

Das A, Cui X, Chivukula V, Iyer SS.

Anal Chem. 2018 Oct 2;90(19):11589-11598. doi: 10.1021/acs.analchem.8b02960. Epub 2018 Sep 21.


Vulnerabilities and risks of HIV infection among migrants in the Thane district, India.

Chowdhury D, Saravanamurthy PS, Chakrabartty A, Purohit S, Iyer SS, Agarwal A, Gopal KM, Mishra P.

Public Health. 2018 Nov;164:49-56. doi: 10.1016/j.puhe.2018.07.019. Epub 2018 Sep 3.


Toxicity and Antigenotoxic Effect of Hispolon Derivatives: Role of Structure in Modulating Cellular Redox State and Thioredoxin Reductase.

Chethna P, Iyer SS, Gandhi VV, Kunwar A, Singh BG, Barik A, Balaji NV, Ramani MV, Subbaraju GV, Priyadarsini KI.

ACS Omega. 2018 Jun 30;3(6):5958-5970. doi: 10.1021/acsomega.8b00415. Epub 2018 Jun 1.


Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol.

Oldbury JW, Wain RAJ, Abas S, Dobson CM, Iyer SS.

J Skin Cancer. 2018 Jun 3;2018:6061395. doi: 10.1155/2018/6061395. eCollection 2018.


Fluid Phase Coexistence in Biological Membrane: Insights from Local Nonaffine Deformation of Lipids.

Iyer SS, Tripathy M, Srivastava A.

Biophys J. 2018 Jul 3;115(1):117-128. doi: 10.1016/j.bpj.2018.05.021.


Mast Cell Proteases Activate Astrocytes and Glia-Neurons and Release Interleukin-33 by Activating p38 and ERK1/2 MAPKs and NF-κB.

Kempuraj D, Thangavel R, Selvakumar GP, Ahmed ME, Zaheer S, Raikwar SP, Zahoor H, Saeed D, Dubova I, Giler G, Herr S, Iyer SS, Zaheer A.

Mol Neurobiol. 2019 Mar;56(3):1681-1693. doi: 10.1007/s12035-018-1177-7. Epub 2018 Jun 18.


Discrete roles of trehalose and Hsp104 in inhibition of protein aggregation in yeast cells.

Sethi R, Iyer SS, Das E, Roy I.

FEMS Yeast Res. 2018 Sep 1;18(6). doi: 10.1093/femsyr/foy058.


Ophthalmic artery occlusion after chiropractic neck manipulation.

Regan KA, Youn TS, Iyer SSR.

Acta Ophthalmol. 2018 Aug;96(5):e663-e664. doi: 10.1111/aos.13738. Epub 2018 May 31. No abstract available.


Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses.

Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F, Lavin R, Serra C, Glickman J, de Silva PSA, Sartor RB, Besra G, Hauser R, Maxwell A, Llebaria A, Blumberg RS.

Cell. 2018 May 17;173(5):1123-1134.e11. doi: 10.1016/j.cell.2018.04.037.


Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer's Disease Therapeutic Target.

Raikwar SP, Thangavel R, Dubova I, Selvakumar GP, Ahmed ME, Kempuraj D, Zaheer SA, Iyer SS, Zaheer A.

Mol Neurobiol. 2019 Jan;56(1):378-393. doi: 10.1007/s12035-018-1068-y. Epub 2018 Apr 27.


Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming.

Elliott EI, Miller AN, Banoth B, Iyer SS, Stotland A, Weiss JP, Gottlieb RA, Sutterwala FS, Cassel SL.

J Immunol. 2018 May 1;200(9):3047-3052. doi: 10.4049/jimmunol.1701723. Epub 2018 Mar 30.


A scalable and deformable stylized model of the adult human eye for radiation dose assessment.

El Basha D, Furuta T, Iyer SSR, Bolch WE.

Phys Med Biol. 2018 May 17;63(10):105017. doi: 10.1088/1361-6560/aab955.


A Young Patient With Floaters.

Lukowski ZL, Regan KA, Iyer SSR.

JAMA Ophthalmol. 2018 Jun 1;136(6):712-713. doi: 10.1001/jamaophthalmol.2017.5485. No abstract available.


Intralenticular Ozurdex® - One Year Later.

Regan KA, Blake CR, Lukowski ZL, Iyer SSR.

Case Rep Ophthalmol. 2017 Dec 21;8(3):590-594. doi: 10.1159/000485318. eCollection 2017 Sep-Dec.


Vision loss secondary to orbital extension of rhabdomyosarcoma in an adult.

Levenson JN, Regan KA, Asirvatham JR, Iyer SS.

Clin Exp Ophthalmol. 2018 Sep;46(7):831-833. doi: 10.1111/ceo.13169. Epub 2018 Mar 5. No abstract available.


Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells.

Selvakumar GP, Iyer SS, Kempuraj D, Raju M, Thangavel R, Saeed D, Ahmed ME, Zahoor H, Raikwar SP, Zaheer S, Zaheer A.

Mol Neurobiol. 2018 Sep;55(9):7132-7152. doi: 10.1007/s12035-018-0882-6. Epub 2018 Jan 30.


Editorial: CD4 T Follicular Helper Cells in HIV.

Iyer SS.

Front Immunol. 2017 Dec 22;8:1894. doi: 10.3389/fimmu.2017.01894. eCollection 2017. No abstract available.


Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer's Disease Pathogenesis.

Kempuraj D, Selvakumar GP, Thangavel R, Ahmed ME, Zaheer S, Raikwar SP, Iyer SS, Bhagavan SM, Beladakere-Ramaswamy S, Zaheer A.

Front Neurosci. 2017 Dec 12;11:703. doi: 10.3389/fnins.2017.00703. eCollection 2017. Review.


Co-Expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer's Disease Brain.

Thangavel R, Bhagavan SM, Ramaswamy SB, Surpur S, Govindarajan R, Kempuraj D, Zaheer S, Raikwar S, Ahmed ME, Selvakumar GP, Iyer SS, Zaheer A.

J Alzheimers Dis. 2018;61(2):553-560. doi: 10.3233/JAD-170777.


Multivalent oleanolic acid human serum albumin conjugate as nonglycosylated neomucin for influenza virus capture and entry inhibition.

Yang Y, He HJ, Chang H, Yu Y, Yang MB, He Y, Fan ZC, Iyer SS, Yu P.

Eur J Med Chem. 2018 Jan 1;143:1723-1731. doi: 10.1016/j.ejmech.2017.10.070. Epub 2017 Oct 28.


Effect of finishing/polishing techniques and time on surface roughness of esthetic restorative materials.

Madhyastha PS, Hegde S, Srikant N, Kotian R, Iyer SS.

Dent Res J (Isfahan). 2017 Sep-Oct;14(5):326-330.


Knowledge and Awareness of First Aid of Avulsed Tooth among Physicians and Nurses of Hospital Emergency Department.

Iyer SS, Panigrahi A, Sharma S.

J Pharm Bioallied Sci. 2017 Apr-Jun;9(2):94-98. doi: 10.4103/jpbs.JPBS_343_16.


Highly specific and rapid glycan based amperometric detection of influenza viruses.

Cui X, Das A, Dhawane AN, Sweeney J, Zhang X, Chivukula V, Iyer SS.

Chem Sci. 2017 May 1;8(5):3628-3634. doi: 10.1039/c6sc03720h. Epub 2017 Feb 14.


Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease Brain.

Thangavel R, Kempuraj D, Zaheer S, Raikwar S, Ahmed ME, Selvakumar GP, Iyer SS, Zaheer A.

Front Aging Neurosci. 2017 May 18;9:150. doi: 10.3389/fnagi.2017.00150. eCollection 2017.


Characteristics of HIV target CD4 T cells collected using different sampling methods from the genital tract of HIV seronegative women.

Iyer SS, Sabula MJ, Mehta CC, Haddad LB, Brown NL, Amara RR, Ofotokun I, Sheth AN.

PLoS One. 2017 Jun 1;12(6):e0178193. doi: 10.1371/journal.pone.0178193. eCollection 2017.


Neuroinflammation Induces Neurodegeneration.

Kempuraj D, Thangavel R, Natteru PA, Selvakumar GP, Saeed D, Zahoor H, Zaheer S, Iyer SS, Zaheer A.

J Neurol Neurosurg Spine. 2016;1(1). pii: 1003. Epub 2016 Nov 18.


Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness.

Iyer SS, Bibollet-Ruche F, Sherrill-Mix S, Learn GH, Plenderleith L, Smith AG, Barbian HJ, Russell RM, Gondim MV, Bahari CY, Shaw CM, Li Y, Decker T, Haynes BF, Shaw GM, Sharp PM, Borrow P, Hahn BH.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E590-E599. doi: 10.1073/pnas.1620144114. Epub 2017 Jan 9.

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