Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 74

1.

Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication.

Athreya AP, Neavin D, Carrillo-Roa T, Skime M, Biernacka J, Frye MA, Rush AJ, Wang L, Binder EB, Iyer RK, Weinshilboum RM, Bobo WV.

Clin Pharmacol Ther. 2019 Apr 23. doi: 10.1002/cpt.1482. [Epub ahead of print]

PMID:
31012492
2.

Human Verbal Memory Encoding Is Hierarchically Distributed in a Continuous Processing Stream.

Kucewicz MT, Saboo K, Berry BM, Kremen V, Miller LR, Khadjevand F, Inman CS, Wanda P, Sperling MR, Gorniak R, Davis KA, Jobst BC, Lega B, Sheth SA, Rizzuto DS, Iyer RK, Kahana MJ, Worrell GA.

eNeuro. 2019 Mar 4;6(1). pii: ENEURO.0214-18.2018. doi: 10.1523/ENEURO.0214-18.2018. eCollection 2019 Jan-Feb.

3.

Genomic and molecular characterization of preterm birth.

Knijnenburg TA, Vockley JG, Chambwe N, Gibbs DL, Humphries C, Huddleston KC, Klein E, Kothiyal P, Tasseff R, Dhankani V, Bodian DL, Wong WSW, Glusman G, Mauldin DE, Miller M, Slagel J, Elasady S, Roach JC, Kramer R, Leinonen K, Linthorst J, Baveja R, Baker R, Solomon BD, Eley G, Iyer RK, Maxwell GL, Bernard B, Shmulevich I, Hood L, Niederhuber JE.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5819-5827. doi: 10.1073/pnas.1716314116. Epub 2019 Mar 4.

4.

Detection and visualization of complex structural variants from long reads.

Stephens Z, Wang C, Iyer RK, Kocher JP.

BMC Bioinformatics. 2018 Dec 21;19(Suppl 20):508. doi: 10.1186/s12859-018-2539-x.

5.

Machine Learning Helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer.

Athreya AP, Gaglio AJ, Cairns J, Kalari KR, Weinshilboum RM, Wang L, Kalbarczyk ZT, Iyer RK.

IEEE Trans Nanobioscience. 2018 Jul;17(3):251-259. doi: 10.1109/TNB.2018.2851997. Epub 2018 Jul 2.

6.

Industrializing Autologous Adoptive Immunotherapies: Manufacturing Advances and Challenges.

Iyer RK, Bowles PA, Kim H, Dulgar-Tulloch A.

Front Med (Lausanne). 2018 May 23;5:150. doi: 10.3389/fmed.2018.00150. eCollection 2018. Review.

7.

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T, Nakamura Y, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM.

Transl Psychiatry. 2018 Jan 10;8(1):10. doi: 10.1038/s41398-017-0056-8.

8.

Surgeon Training in Telerobotic Surgery via a Hardware-in-the-Loop Simulator.

Li X, Alemzadeh H, Chen D, Kalbarczyk Z, Iyer RK, Kesavadas T.

J Healthc Eng. 2017;2017:6702919. doi: 10.1155/2017/6702919. Epub 2017 Aug 3.

9.

Prediction of adenocarcinoma development using game theory.

Athreya AP, Armstrong D, Gundling W, Wildman D, Kalbarczyk ZT, Iyer RK.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1668-1671. doi: 10.1109/EMBC.2017.8037161.

PMID:
29060205
10.

Utilization of genomic sequencing for population screening of immunodeficiencies in the newborn.

Pavey AR, Bodian DL, Vilboux T, Khromykh A, Hauser NS, Huddleston K, Klein E, Black A, Kane MS, Iyer RK, Niederhuber JE, Solomon BD.

Genet Med. 2017 Dec;19(12):1367-1375. doi: 10.1038/gim.2017.57. Epub 2017 Jun 15.

PMID:
28617419
11.

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer.

Athreya AP, Kalari KR, Cairns J, Gaglio AJ, Wills QF, Niu N, Weinshilboum R, Iyer RK, Wang L.

Oncotarget. 2017 Apr 18;8(16):27199-27215. doi: 10.18632/oncotarget.16109.

12.

Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models.

Stephens ZD, Hudson ME, Mainzer LS, Taschuk M, Weber MR, Iyer RK.

PLoS One. 2016 Nov 28;11(11):e0167047. doi: 10.1371/journal.pone.0167047. eCollection 2016.

13.

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation.

Mordant P, Nakajima D, Kalaf R, Iskender I, Maahs L, Behrens P, Coutinho R, Iyer RK, Davies JE, Cypel M, Liu M, Waddell TK, Keshavjee S.

J Heart Lung Transplant. 2016 Oct;35(10):1245-1254. doi: 10.1016/j.healun.2016.04.017. Epub 2016 May 6.

PMID:
27444694
14.

Seizure Forecasting and the Preictal State in Canine Epilepsy.

Varatharajah Y, Iyer RK, Berry BM, Worrell GA, Brinkmann BH.

Int J Neural Syst. 2017 Feb;27(1):1650046. Epub 2016 Jun 14.

15.

Adverse Events in Robotic Surgery: A Retrospective Study of 14 Years of FDA Data.

Alemzadeh H, Raman J, Leveson N, Kalbarczyk Z, Iyer RK.

PLoS One. 2016 Apr 20;11(4):e0151470. doi: 10.1371/journal.pone.0151470. eCollection 2016.

16.

New observations on maternal age effect on germline de novo mutations.

Wong WS, Solomon BD, Bodian DL, Kothiyal P, Eley G, Huddleston KC, Baker R, Thach DC, Iyer RK, Vockley JG, Niederhuber JE.

Nat Commun. 2016 Jan 19;7:10486. doi: 10.1038/ncomms10486.

17.

Diagnosis of D-Bifunctional Protein Deficiency through Whole-Genome Sequencing: Implications for Cost-Effective Care.

Khromykh A, Solomon BD, Bodian DL, Leon EL, Iyer RK, Baker RL, Ascher DP, Baveja R, Vockley JG, Niederhuber JE.

Mol Syndromol. 2015 Sep;6(3):141-6. doi: 10.1159/000433621. Epub 2015 Jul 3.

18.

Utility of whole-genome sequencing for detection of newborn screening disorders in a population cohort of 1,696 neonates.

Bodian DL, Klein E, Iyer RK, Wong WS, Kothiyal P, Stauffer D, Huddleston KC, Gaither AD, Remsburg I, Khromykh A, Baker RL, Maxwell GL, Vockley JG, Niederhuber JE, Solomon BD.

Genet Med. 2016 Mar;18(3):221-30. doi: 10.1038/gim.2015.111. Epub 2015 Sep 3.

PMID:
26334177
19.

Expanding the phenotypic spectrum in EP300-related Rubinstein-Taybi syndrome.

Solomon BD, Bodian DL, Khromykh A, Mora GG, Lanpher BC, Iyer RK, Baveja R, Vockley JG, Niederhuber JE.

Am J Med Genet A. 2015 May;167A(5):1111-6. doi: 10.1002/ajmg.a.36883. Epub 2015 Feb 25.

PMID:
25712426
20.

Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio.

Bodian DL, Solomon BD, Khromykh A, Thach DC, Iyer RK, Link K, Baker RL, Baveja R, Vockley JG, Niederhuber JE.

Mol Genet Genomic Med. 2014 Nov;2(6):530-8. doi: 10.1002/mgg3.107. Epub 2014 Aug 26.

21.

Mutations in NOTCH1 cause Adams-Oliver syndrome.

Stittrich AB, Lehman A, Bodian DL, Ashworth J, Zong Z, Li H, Lam P, Khromykh A, Iyer RK, Vockley JG, Baveja R, Silva ES, Dixon J, Leon EL, Solomon BD, Glusman G, Niederhuber JE, Roach JC, Patel MS.

Am J Hum Genet. 2014 Sep 4;95(3):275-84. doi: 10.1016/j.ajhg.2014.07.011. Epub 2014 Aug 14.

22.

Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

Bodian DL, McCutcheon JN, Kothiyal P, Huddleston KC, Iyer RK, Vockley JG, Niederhuber JE.

PLoS One. 2014 Apr 11;9(4):e94554. doi: 10.1371/journal.pone.0094554. eCollection 2014.

23.

Development of a genomic DNA reference material panel for Rett syndrome (MECP2-related disorders) genetic testing.

Kalman LV, Tarleton JC, Percy AK, Aradhya S, Bale S, Barker SD, Bayrak-Toydemir P, Bridges C, Buller-Burckle AM, Das S, Iyer RK, Vo TD, Zvereff VV, Toji LH.

J Mol Diagn. 2014 Mar;16(2):273-9. doi: 10.1016/j.jmoldx.2013.11.004. Epub 2014 Feb 7.

24.

Future drugs for the treatment of dry cough.

Iyer RK, Joshi JM.

J Assoc Physicians India. 2013 May;61(5 Suppl):14-6.

PMID:
24490444
25.

Gram stains: a resource for retrospective analysis of bacterial pathogens in clinical studies.

Srinivasan U, Ponnaluri S, Villareal L, Gillespie B, Wen A, Miles A, Bucholz B, Marrs CF, Iyer RK, Misra D, Foxman B.

PLoS One. 2012;7(10):e42898. doi: 10.1371/journal.pone.0042898. Epub 2012 Oct 11.

26.
27.

Vascular endothelial growth factor secretion by nonmyocytes modulates Connexin-43 levels in cardiac organoids.

Iyer RK, Odedra D, Chiu LL, Vunjak-Novakovic G, Radisic M.

Tissue Eng Part A. 2012 Sep;18(17-18):1771-83. doi: 10.1089/ten.TEA.2011.0468. Epub 2012 Aug 6.

28.

Chromosome 4q deletion syndrome: narrowing the cardiovascular critical region to 4q32.2-q34.3.

Xu W, Ahmad A, Dagenais S, Iyer RK, Innis JW.

Am J Med Genet A. 2012 Mar;158A(3):635-40. doi: 10.1002/ajmg.a.34425. Epub 2012 Feb 2.

29.

An embedded reconfigurable architecture for patient-specific multi-paramater medical monitoring.

Alemzadeh H, Jin Z, Kalbarczyk Z, Iyer RK.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1896-900. doi: 10.1109/IEMBS.2011.6090537.

PMID:
22254701
30.

Cardiac tissue engineering: current state and perspectives.

Chiu LL, Iyer RK, Reis LA, Nunes SS, Radisic M.

Front Biosci (Landmark Ed). 2012 Jan 1;17:1533-50.

PMID:
22201819
31.

An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities.

Kaminsky EB, Kaul V, Paschall J, Church DM, Bunke B, Kunig D, Moreno-De-Luca D, Moreno-De-Luca A, Mulle JG, Warren ST, Richard G, Compton JG, Fuller AE, Gliem TJ, Huang S, Collinson MN, Beal SJ, Ackley T, Pickering DL, Golden DM, Aston E, Whitby H, Shetty S, Rossi MR, Rudd MK, South ST, Brothman AR, Sanger WG, Iyer RK, Crolla JA, Thorland EC, Aradhya S, Ledbetter DH, Martin CL.

Genet Med. 2011 Sep;13(9):777-84. doi: 10.1097/GIM.0b013e31822c79f9.

32.

Engineered cardiac tissues.

Iyer RK, Chiu LL, Reis LA, Radisic M.

Curr Opin Biotechnol. 2011 Oct;22(5):706-14. doi: 10.1016/j.copbio.2011.04.004. Epub 2011 Apr 27. Review.

33.

Multiple congenital anomalies and developmental delay in a boy associated with a de novo 16p13.3 deletion.

Nelson M, Quinonez S, Ackley T, Iyer RK, Innis JW.

Am J Med Genet A. 2011 Mar;155A(3):612-7. doi: 10.1002/ajmg.a.33808. Epub 2011 Feb 22.

PMID:
21344629
34.

Copy number variations and clinical outcome in atypical spitz tumors.

Raskin L, Ludgate M, Iyer RK, Ackley TE, Bradford CR, Johnson TM, Fullen DR.

Am J Surg Pathol. 2011 Feb;35(2):243-52. doi: 10.1097/PAS.0b013e31820393ee.

PMID:
21263245
35.

A complex 6p25 rearrangement in a child with multiple epiphyseal dysplasia.

Bedoyan JK, Lesperance MM, Ackley T, Iyer RK, Innis JW, Misra VK.

Am J Med Genet A. 2011 Jan;155A(1):154-63. doi: 10.1002/ajmg.a.33751. Epub 2010 Dec 10.

36.

Deletion at chromosomal band Xp22.12-Xp22.13 involving PDHA1 in a patient with congenital lactic acidosis.

Singer BH, Iyer RK, Kerr DS, Ahmad A.

Mol Genet Metab. 2010 Sep;101(1):87-9. doi: 10.1016/j.ymgme.2010.05.008. Epub 2010 Jun 11.

PMID:
20591708
37.

Duplication 16p11.2 in a child with infantile seizure disorder.

Bedoyan JK, Kumar RA, Sudi J, Silverstein F, Ackley T, Iyer RK, Christian SL, Martin DM.

Am J Med Genet A. 2010 Jun;152A(6):1567-74. doi: 10.1002/ajmg.a.33415.

38.

Influence of substrate stiffness on the phenotype of heart cells.

Bhana B, Iyer RK, Chen WL, Zhao R, Sider KL, Likhitpanichkul M, Simmons CA, Radisic M.

Biotechnol Bioeng. 2010 Apr 15;105(6):1148-60. doi: 10.1002/bit.22647.

PMID:
20014437
39.

Engineering surfaces for site-specific vascular differentiation of mouse embryonic stem cells.

Chiang CK, Chowdhury MF, Iyer RK, Stanford WL, Radisic M.

Acta Biomater. 2010 Jun;6(6):1904-16. doi: 10.1016/j.actbio.2009.12.005. Epub 2009 Dec 11.

PMID:
20004260
40.

Controlled capture and release of cardiac fibroblasts using peptide-functionalized alginate gels in microfluidic channels.

Plouffe BD, Brown MA, Iyer RK, Radisic M, Murthy SK.

Lab Chip. 2009 Jun 7;9(11):1507-10. doi: 10.1039/b823523f. Epub 2009 Mar 12.

PMID:
19458855
41.

Spatiotemporal tracking of cells in tissue-engineered cardiac organoids.

Iyer RK, Chui J, Radisic M.

J Tissue Eng Regen Med. 2009 Mar;3(3):196-207. doi: 10.1002/term.153.

42.

Pulsatile perfusion bioreactor for cardiac tissue engineering.

Brown MA, Iyer RK, Radisic M.

Biotechnol Prog. 2008 Jul-Aug;24(4):907-20. doi: 10.1002/btpr.11.

PMID:
19194900
43.

Optical mapping of impulse propagation in engineered cardiac tissue.

Radisic M, Fast VG, Sharifov OF, Iyer RK, Park H, Vunjak-Novakovic G.

Tissue Eng Part A. 2009 Apr;15(4):851-60. doi: 10.1089/ten.tea.2008.0223.

44.

Biphasic electrical field stimulation aids in tissue engineering of multicell-type cardiac organoids.

Chiu LL, Iyer RK, King JP, Radisic M.

Tissue Eng Part A. 2011 Jun;17(11-12):1465-77. doi: 10.1089/ten.tea.2007.0244. Epub 2008 Sep 10.

45.

Microfabricated poly(ethylene glycol) templates enable rapid screening of triculture conditions for cardiac tissue engineering.

Iyer RK, Chiu LL, Radisic M.

J Biomed Mater Res A. 2009 Jun;89(3):616-31. doi: 10.1002/jbm.a.32014.

PMID:
18442120
46.

Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia.

Deignan JL, Marescau B, Livesay JC, Iyer RK, De Deyn PP, Cederbaum SD, Grody WW.

Mol Genet Metab. 2008 Feb;93(2):172-8. Epub 2007 Nov 7.

PMID:
17997338
47.

Micro- and nanotechnology in cell separation.

Radisic M, Iyer RK, Murthy SK.

Int J Nanomedicine. 2006;1(1):3-14. Review.

48.

Polyamine homeostasis in arginase knockout mice.

Deignan JL, Livesay JC, Shantz LM, Pegg AE, O'Brien WE, Iyer RK, Cederbaum SD, Grody WW.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1296-301. Epub 2007 Aug 8.

49.

Synthetic oxygen carriers in cardiac tissue engineering.

Iyer RK, Radisic M, Cannizzaro C, Vunjak-Novakovic G.

Artif Cells Blood Substit Immobil Biotechnol. 2007;35(1):135-48. Review.

PMID:
17364478
50.

Arginase induction by sodium phenylbutyrate in mouse tissues and human cell lines.

Kern RM, Yang Z, Kim PS, Grody WW, Iyer RK, Cederbaum SD.

Mol Genet Metab. 2007 Jan;90(1):37-41. Epub 2006 Aug 28.

PMID:
16935537

Supplemental Content

Support Center