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Items: 1 to 50 of 152

1.

Nanoparticles for Immune Cell Reprogramming and Reengineering of Tumor Microenvironment.

Bhise K, Sau S, Alzhrani R, Iyer AK.

Methods Mol Biol. 2020;2097:211-221. doi: 10.1007/978-1-0716-0203-4_13.

PMID:
31776928
2.

Discovering pH triggered charge rebound surface modulated topical nanotherapy against aggressive skin papilloma.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Iyer AK.

Mater Sci Eng C Mater Biol Appl. 2020 Feb;107:110263. doi: 10.1016/j.msec.2019.110263. Epub 2019 Oct 12.

PMID:
31761163
3.

Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems.

Alzhrani R, Alsaab HO, Petrovici A, Bhise K, Vanamala K, Sau S, Krinock MJ, Iyer AK.

Drug Discov Today. 2019 Nov 20. pii: S1359-6446(19)30427-1. doi: 10.1016/j.drudis.2019.11.006. [Epub ahead of print] Review.

PMID:
31758914
4.

Consideration of Aggressive and Strategic Approaches to Address Declining Enrollment in US Pharmacy Schools.

Pavuluri N, Aparasu RR, Boje KMK, Danielson J, El-Ibiary SY, Iyer AKV, Ochs LA, Robinson JD, Shah S, Williams CC, Moore TM, Wargo KA.

Am J Pharm Educ. 2019 Aug;83(6):6959. doi: 10.5688/ajpe6959. Review.

5.

An Old Dog with New Tricks - Additions to the Cesium Lithium Chloride System: Cs3Li2Cl5 and the Hydrated Cs3LiCl4 · 4H2O.

Ortner TS, Scheifers JP, Flores J, Zhang Y, Iyer AK, Gesing TM, Fokwa BPT.

Eur J Inorg Chem. 2019 Aug 15;2019(30):3526-3535. doi: 10.1002/ejic.201900774. Epub 2019 Jul 19.

PMID:
31501644
6.

Alkaline Earth Metal-Organic Frameworks with Tailorable Ion Release: A Path for Supporting Biomineralization.

Matlinska MA, Ha M, Hughton B, Oliynyk AO, Iyer AK, Bernard GM, Lambkin G, Lawrence MC, Katz MJ, Mar A, Michaelis VK.

ACS Appl Mater Interfaces. 2019 Sep 11;11(36):32739-32745. doi: 10.1021/acsami.9b11004. Epub 2019 Aug 27.

PMID:
31414791
7.

Nanomaterials for tumor immunomodulation and overcoming current clinical challenges.

Sau S, Alzhrani R, Bhise K, Alsaab HO, Kashaw SK, Iyer AK.

Nanomedicine (Lond). 2019 Jun;14(12):1515-1519. doi: 10.2217/nnm-2019-0109. Epub 2019 Jun 24. No abstract available.

8.

The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells.

Yakisich JS, Azad N, Kaushik V, Iyer AKV.

Stem Cells Int. 2019 Feb 21;2019:6254269. doi: 10.1155/2019/6254269. eCollection 2019.

9.

PDL-1 Antibody Drug Conjugate for Selective Chemo-Guided Immune Modulation of Cancer.

Sau S, Petrovici A, Alsaab HO, Bhise K, Iyer AK.

Cancers (Basel). 2019 Feb 16;11(2). pii: E232. doi: 10.3390/cancers11020232.

10.

pH triggered and charge attracted nanogel for simultaneous evaluation of penetration and toxicity against skin cancer: In-vitro and ex-vivo study.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Int J Biol Macromol. 2019 May 1;128:740-751. doi: 10.1016/j.ijbiomac.2019.01.147. Epub 2019 Jan 27.

PMID:
30699336
11.

Development of asialoglycoprotein receptor directed nanoparticles for selective delivery of curcumin derivative to hepatocellular carcinoma.

Yousef S, Alsaab HO, Sau S, Iyer AK.

Heliyon. 2018 Dec 22;4(12):e01071. doi: 10.1016/j.heliyon.2018.e01071. eCollection 2018 Dec.

12.

JNK2 modulates the CD1d-dependent and -independent activation of iNKT cells.

Liu J, Gallo RM, Khan MA, Iyer AK, Kratzke IM, Brutkiewicz RR.

Eur J Immunol. 2019 Feb;49(2):255-265. doi: 10.1002/eji.201847755. Epub 2018 Dec 3.

PMID:
30467836
13.

pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Colloids Surf B Biointerfaces. 2019 Feb 1;174:232-245. doi: 10.1016/j.colsurfb.2018.11.018. Epub 2018 Nov 10.

PMID:
30465998
14.

Exploring the Role of Water Molecules in the Ligand Binding Domain of PDE4B and PDE4D: Virtual Screening Based Molecular Docking of Some Active Scaffolds.

Singh P, Mishra M, Agarwal S, Sau S, Iyer AK, Kashaw SK.

Curr Comput Aided Drug Des. 2019;15(4):334-366. doi: 10.2174/1573409914666181105153543.

PMID:
30394213
15.

Not Just Par for the Course: 73 Quaternary Germanides RE4 M2 XGe4 ( RE = La-Nd, Sm, Gd-Tm, Lu; M = Mn-Ni; X = Ag, Cd) and the Search for Intermetallics with Low Thermal Conductivity.

Zhang D, Oliynyk AO, Duarte GM, Iyer AK, Ghadbeigi L, Kauwe SK, Sparks TD, Mar A.

Inorg Chem. 2018 Nov 19;57(22):14249-14259. doi: 10.1021/acs.inorgchem.8b02279. Epub 2018 Oct 26.

PMID:
30365327
16.

Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents.

Kashaw SK, Agarwal S, Mishra M, Sau S, Iyer AK.

Curr Comput Aided Drug Des. 2019;15(1):55-66. doi: 10.2174/1573409914666181015150731.

PMID:
30324892
17.

Ionophores: Potential Use as Anticancer Drugs and Chemosensitizers.

Kaushik V, Yakisich JS, Kumar A, Azad N, Iyer AKV.

Cancers (Basel). 2018 Sep 27;10(10). pii: E360. doi: 10.3390/cancers10100360. Review.

18.

Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients.

Sau S, Iyer AK.

J Thorac Dis. 2018 Aug;10(8):4682-4685. doi: 10.21037/jtd.2018.07.66. No abstract available.

19.

Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening.

Kaushik V, Yakisich JS, Way LF, Azad N, Iyer AKV.

J Cell Physiol. 2019 Apr;234(4):4445-4453. doi: 10.1002/jcp.27239. Epub 2018 Sep 7.

PMID:
30191978
20.

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Alsaab HO, Sau S, Alzhrani RM, Cheriyan VT, Polin LA, Vaishampayan U, Rishi AK, Iyer AK.

Biomaterials. 2018 Nov;183:280-294. doi: 10.1016/j.biomaterials.2018.08.053. Epub 2018 Aug 30.

21.

Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation.

Nabil G, Bhise K, Sau S, Atef M, El-Banna HA, Iyer AK.

Drug Discov Today. 2019 Feb;24(2):462-491. doi: 10.1016/j.drudis.2018.08.009. Epub 2018 Aug 16. Review.

PMID:
30121330
22.

A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers.

Cheriyan VT, Alsaab H, Sekhar S, Venkatesh J, Mondal A, Vhora I, Sau S, Muthu M, Polin LA, Levi E, Bepler G, Iyer AK, Singh M, Rishi AK.

Oncotarget. 2018 Jul 3;9(51):29680-29697. doi: 10.18632/oncotarget.25671. eCollection 2018 Jul 3.

23.

Combination of Vancomycin and Cefazolin Lipid Nanoparticles for Overcoming Antibiotic Resistance of MRSA.

Bhise K, Sau S, Kebriaei R, Rice SA, Stamper KC, Alsaab HO, Rybak MJ, Iyer AK.

Materials (Basel). 2018 Jul 20;11(7). pii: E1245. doi: 10.3390/ma11071245.

24.

Intracranial Hemorrhage in Deep Vein Thrombosis/Pulmonary Embolus Patients Without Atrial Fibrillation.

Lamsam L, Sussman ES, Iyer AK, Bhambhvani HP, Han SS, Skirboll S, Ratliff JK.

Stroke. 2018 Aug;49(8):1866-1871. doi: 10.1161/STROKEAHA.118.022156.

PMID:
29991654
25.

An integrated computational approach of molecular dynamics simulations, receptor binding studies and pharmacophore mapping analysis in search of potent inhibitors against tuberculosis.

Agarwal S, Verma E, Kumar V, Lall N, Sau S, Iyer AK, Kashaw SK.

J Mol Graph Model. 2018 Aug;83:17-32. doi: 10.1016/j.jmgm.2018.04.019. Epub 2018 May 3.

PMID:
29753941
26.

A student perspective: Medical students and intimate examinations.

Bhanot R, Iyer AK.

Med Teach. 2018 Sep;40(9):972-973. doi: 10.1080/0142159X.2018.1463434. Epub 2018 Apr 24. No abstract available.

PMID:
29688107
27.

CD44 directed nanomicellar payload delivery platform for selective anticancer effect and tumor specific imaging of triple negative breast cancer.

Wang Z, Sau S, Alsaab HO, Iyer AK.

Nanomedicine. 2018 Jun;14(4):1441-1454. doi: 10.1016/j.nano.2018.04.004. Epub 2018 Apr 17.

28.

Paclitaxel and di-fluorinated curcumin loaded in albumin nanoparticles for targeted synergistic combination therapy of ovarian and cervical cancers.

Gawde KA, Sau S, Tatiparti K, Kashaw SK, Mehrmohammadi M, Azmi AS, Iyer AK.

Colloids Surf B Biointerfaces. 2018 Jul 1;167:8-19. doi: 10.1016/j.colsurfb.2018.03.046. Epub 2018 Mar 28.

PMID:
29625422
29.

A tumor multicomponent targeting chemoimmune drug delivery system for reprograming the tumor microenvironment and personalized cancer therapy.

Sau S, Tatiparti K, Alsaab HO, Kashaw SK, Iyer AK.

Drug Discov Today. 2018 Jul;23(7):1344-1356. doi: 10.1016/j.drudis.2018.03.003. Epub 2018 Mar 15. Review.

30.
31.

Temporospatial Analysis and New Players in the Immunology of Amyotrophic Lateral Sclerosis.

Iyer AK, Jones KJ, Sanders VM, Walker CL.

Int J Mol Sci. 2018 Feb 23;19(2). pii: E631. doi: 10.3390/ijms19020631. Review.

32.

Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor environment.

Sau S, Alsaab HO, Bhise K, Alzhrani R, Nabil G, Iyer AK.

J Control Release. 2018 Mar 28;274:24-34. doi: 10.1016/j.jconrel.2018.01.028. Epub 2018 Jan 31. Review.

33.

A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma.

Cheriyan VT, Alsaab HO, Sekhar S, Stieber C, Kesharwani P, Sau S, Muthu M, Polin LA, Levi E, Iyer AK, Rishi AK.

Oncotarget. 2017 Sep 5;8(62):104928-104945. doi: 10.18632/oncotarget.20650. eCollection 2017 Dec 1.

34.

A Lipidomics Approach to Identifying Key Lipid Species Involved in VEGF-Inhibitor Mediated Attenuation of Bleomycin-Induced Pulmonary Fibrosis.

Kulkarni YM, Dutta S, Iyer AKV, Wright CA, Ramesh V, Kaushik V, Semmes OJ, Azad N.

Proteomics Clin Appl. 2018 May;12(3):e1700086. doi: 10.1002/prca.201700086. Epub 2018 Jan 19.

35.

Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib.

Yakisich JS, Kulkarni Y, Azad N, Iyer AKV.

Stem Cells Int. 2017;2017:5987015. doi: 10.1155/2017/5987015. Epub 2017 Oct 19.

36.

Translational gap in ongoing clinical trials for glioma.

Guishard AF, Yakisich JS, Azad N, Iyer AKV.

J Clin Neurosci. 2018 Jan;47:28-42. doi: 10.1016/j.jocn.2017.10.001. Epub 2017 Oct 21. Review.

37.

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.

Xie H, Hoffmann HM, Iyer AK, Brayman MJ, Ngo C, Sunshine MJ, Mellon PL.

Reprod Biol Endocrinol. 2017 Oct 24;15(1):86. doi: 10.1186/s12958-017-0304-z.

38.

Nanomedicine for cancer diagnosis and therapy: advancement, success and structure-activity relationship.

Bhise K, Sau S, Alsaab H, Kashaw SK, Tekade RK, Iyer AK.

Ther Deliv. 2017 Nov;8(11):1003-1018. doi: 10.4155/tde-2017-0062. Review.

PMID:
29061101
39.

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome.

Alsaab HO, Sau S, Alzhrani R, Tatiparti K, Bhise K, Kashaw SK, Iyer AK.

Front Pharmacol. 2017 Aug 23;8:561. doi: 10.3389/fphar.2017.00561. eCollection 2017. Review.

40.

pH responsive biodegradable nanogels for sustained release of bleomycin.

Sahu P, Kashaw SK, Kushwah V, Sau S, Jain S, Iyer AK.

Bioorg Med Chem. 2017 Sep 1;25(17):4595-4613. doi: 10.1016/j.bmc.2017.06.038. Epub 2017 Jun 27.

PMID:
28734664
41.

Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy.

Choudhury H, Gorain B, Pandey M, Kumbhar SA, Tekade RK, Iyer AK, Kesharwani P.

Int J Pharm. 2017 Aug 30;529(1-2):506-522. doi: 10.1016/j.ijpharm.2017.07.018. Epub 2017 Jul 12. Review.

PMID:
28711640
42.

Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery.

Kesharwani P, Gothwal A, Iyer AK, Jain K, Chourasia MK, Gupta U.

Drug Discov Today. 2018 Feb;23(2):300-314. doi: 10.1016/j.drudis.2017.06.009. Epub 2017 Jul 8. Review.

PMID:
28697371
43.

Folic acid conjugated polymeric micelles loaded with a curcumin difluorinated analog for targeting cervical and ovarian cancers.

Luong D, Kesharwani P, Alsaab HO, Sau S, Padhye S, Sarkar FH, Iyer AK.

Colloids Surf B Biointerfaces. 2017 Sep 1;157:490-502. doi: 10.1016/j.colsurfb.2017.06.025. Epub 2017 Jun 21.

44.

Advances in antibody-drug conjugates: A new era of targeted cancer therapy.

Sau S, Alsaab HO, Kashaw SK, Tatiparti K, Iyer AK.

Drug Discov Today. 2017 Oct;22(10):1547-1556. doi: 10.1016/j.drudis.2017.05.011. Epub 2017 Jun 13. Review.

45.

Anti-tumorigenic effects of a novel digitoxin derivative on both estrogen receptor-positive and triple-negative breast cancer cells.

Kulkarni YM, Yakisich JS, Azad N, Venkatadri R, Kaushik V, O'Doherty G, Iyer AKV.

Tumour Biol. 2017 Jun;39(6):1010428317705331. doi: 10.1177/1010428317705331.

PMID:
28618929
46.

A novel resveratrol-salinomycin combination sensitizes ER-positive breast cancer cells to apoptosis.

Venkatadri R, Iyer AKV, Kaushik V, Azad N.

Pharmacol Rep. 2017 Aug;69(4):788-797. doi: 10.1016/j.pharep.2017.03.024. Epub 2017 Apr 7.

PMID:
28605700
47.

Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drug.

Sau S, Mondal SK, Kashaw SK, Iyer AK, Banerjee R.

Mol Cell Biochem. 2017 Dec;436(1-2):119-136. doi: 10.1007/s11010-017-3084-z. Epub 2017 Jun 5.

PMID:
28585089
48.

A tale of motor neurons and CD4+ T cells: moving forward by looking back.

Iyer AK, Jones KJ.

Neural Regen Res. 2017 Apr;12(4):562-565. doi: 10.4103/1673-5374.205086. Review.

49.

Gamma Knife Radiosurgery for Vestibular Schwannomas and Quality of Life Evaluation.

Berkowitz O, Han YY, Talbott EO, Iyer AK, Kano H, Kondziolka D, Brown MA, Lunsford LD.

Stereotact Funct Neurosurg. 2017;95(3):166-173. doi: 10.1159/000472156. Epub 2017 May 23.

50.

Nanostructured lipid carriers employing polyphenols as promising anticancer agents: Quality by design (QbD) approach.

Bhise K, Kashaw SK, Sau S, Iyer AK.

Int J Pharm. 2017 Jun 30;526(1-2):506-515. doi: 10.1016/j.ijpharm.2017.04.078. Epub 2017 May 11. Review.

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