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Items: 1 to 50 of 627

1.

Alkaline Earth Metal-Organic Frameworks with Tailorable Ion Release: A Path for Supporting Biomineralization.

Matlinska M, Ha M, Hughton B, Oliynyk AO, Iyer A, Bernard GM, Lambkin GR, Lawrence MC, Katz MJ, Mar A, Michaelis VK.

ACS Appl Mater Interfaces. 2019 Aug 15. doi: 10.1021/acsami.9b11004. [Epub ahead of print]

PMID:
31414791
2.

TB or not TB: Type 3 ILCs may decide.

McManus D, Iyer A, Pillai AB.

Sci Immunol. 2019 Aug 2;4(38). pii: eaay7254. doi: 10.1126/sciimmunol.aay7254.

PMID:
31375529
3.

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation.

Loh Z, Fitzsimmons RL, Reid RC, Ramnath D, Clouston A, Gupta PK, Irvine KM, Powell EE, Schroder K, Stow JL, Sweet MJ, Fairlie DP, Iyer A.

Br J Pharmacol. 2019 Jun 24. doi: 10.1111/bph.14768. [Epub ahead of print]

PMID:
31236923
4.

Nanomaterials for tumor immunomodulation and overcoming current clinical challenges.

Sau S, Alzhrani R, Bhise K, Alsaab HO, Kashaw SK, Iyer AK.

Nanomedicine (Lond). 2019 Jun;14(12):1515-1519. doi: 10.2217/nnm-2019-0109. Epub 2019 Jun 24. No abstract available.

5.

Expression of cancer stem cell markers is prognostic in metastatic gastroesophageal adenocarcinoma.

Brungs D, Lochhead A, Iyer A, Illemann M, Colligan P, Hirst NG, Splitt A, Liauw W, Vine KL, Pathmanandavel S, Carolan M, Becker TM, Aghmesheh M, Ranson M.

Pathology. 2019 Aug;51(5):474-480. doi: 10.1016/j.pathol.2019.03.009. Epub 2019 Jun 20.

PMID:
31230819
6.

Systemic and local corticosteroid use is associated with reduced executive cognition, and mood and anxiety disorders.

Savas M, Vinkers C, Rosmalen J, Hartman C, Wester VL, van den Akker ELT, Iyer A, McEwen BS, van Rossum EFC.

Neuroendocrinology. 2019 Jun 21. doi: 10.1159/000501617. [Epub ahead of print]

PMID:
31220843
7.

Toward personalized dose-prescription in locally advanced non-small cell lung cancer: Validation of published normal tissue complication probability models.

Thor M, Deasy J, Iyer A, Bendau E, Fontanella A, Apte A, Yorke E, Rimner A, Jackson A.

Radiother Oncol. 2019 May 27;138:45-51. doi: 10.1016/j.radonc.2019.05.011. [Epub ahead of print]

PMID:
31146070
8.

International Collaborative Assessment of the Validity of the EAONO-JOS Cholesteatoma Staging System.

James AL, Tono T, Cohen MS, Iyer A, Cooke L, Morita Y, Matsuda K, Yamamoto Y, Sakagami M, Yung M.

Otol Neurotol. 2019 Jun;40(5):630-637. doi: 10.1097/MAO.0000000000002168.

PMID:
31083088
9.

Crystal Structures of Protein-Bound Cyclic Peptides.

Malde AK, Hill TA, Iyer A, Fairlie DP.

Chem Rev. 2019 May 2. doi: 10.1021/acs.chemrev.8b00807. [Epub ahead of print]

PMID:
31046237
10.

A Formative Evaluation of Patient and Family Caregiver Perspectives on Early Palliative Care in Chronic Obstructive Pulmonary Disease across Disease Severity.

Iyer AS, Dionne-Odom JN, Ford SM, Crump Tims SL, Sockwell ED, Ivankova NV, Brown CJ, Tucker RO, Dransfield MT, Bakitas MA.

Ann Am Thorac Soc. 2019 Aug;16(8):1024-1033. doi: 10.1513/AnnalsATS.201902-112OC.

PMID:
31039003
11.

Teixobactins: a new class of 21st century antibiotics to combat multidrug-resistant bacterial pathogens.

Iyer A, Madder A, Singh I.

Future Microbiol. 2019 Apr;14:457-460. doi: 10.2217/fmb-2019-0056. Epub 2019 Apr 29. No abstract available.

PMID:
31033354
12.

Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.

Lyttle MD, Rainford NEA, Gamble C, Messahel S, Humphreys A, Hickey H, Woolfall K, Roper L, Noblet J, Lee ED, Potter S, Tate P, Iyer A, Evans V, Appleton RE; Paediatric Emergency Research in the United Kingdom & Ireland (PERUKI) collaborative.

Lancet. 2019 May 25;393(10186):2125-2134. doi: 10.1016/S0140-6736(19)30724-X. Epub 2019 Apr 17.

13.

Functional Outcomes After Revascularization Procedures in Patients With Hemorrhagic Moyamoya Disease.

Abhinav K, Furtado SV, Nielsen TH, Iyer A, Gooderham PA, Teo M, Lee J, Han SS, Steinberg GK.

Neurosurgery. 2019 Apr 15. pii: nyz074. doi: 10.1093/neuros/nyz074. [Epub ahead of print]

PMID:
30989221
14.

Clonotypic heterogeneity in cutaneous T-cell lymphoma (mycosis fungoides) revealed by comprehensive whole-exome sequencing.

Iyer A, Hennessey D, O'Keefe S, Patterson J, Wang W, Salopek T, Wong GK, Gniadecki R.

Blood Adv. 2019 Apr 9;3(7):1175-1184. doi: 10.1182/bloodadvances.2018027482.

15.

Outcomes of Donation After Circulatory Death Heart Transplantation in Australia.

Chew HC, Iyer A, Connellan M, Scheuer S, Villanueva J, Gao L, Hicks M, Harkness M, Soto C, Dinale A, Nair P, Watson A, Granger E, Jansz P, Muthiah K, Jabbour A, Kotlyar E, Keogh A, Hayward C, Graham R, Spratt P, Macdonald P, Dhital K.

J Am Coll Cardiol. 2019 Apr 2;73(12):1447-1459. doi: 10.1016/j.jacc.2018.12.067.

PMID:
30922476
16.

The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells.

Yakisich JS, Azad N, Kaushik V, Iyer AKV.

Stem Cells Int. 2019 Feb 21;2019:6254269. doi: 10.1155/2019/6254269. eCollection 2019.

17.

Enhancing practitioners' confidence in recruitment and consent in the EcLiPSE trial: a mixed-method evaluation of site training - a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.

Woolfall K, Roper L, Humphreys A, Lyttle MD, Messahel S, Lee E, Noblet J, Iyer A, Gamble C, Hickey H, Rainford N, Appleton R.

Trials. 2019 Mar 21;20(1):181. doi: 10.1186/s13063-019-3273-z.

18.

Symptoms of anxiety and depression and use of anxiolytic-hypnotics and antidepressants in current and former smokers with and without COPD - A cross sectional analysis of the COPDGene cohort.

Iyer AS, Holm KE, Bhatt SP, Kim V, Kinney GL, Wamboldt FS, Jacobs MR, Regan EA, Armstrong HF, Lowe KE, Martinez CH, Dransfield MT, Foreman MG, Shinozaki G, Hanania NA, Wise RA, Make BJ, Hoth KF; COPDGene Investigators.

J Psychosom Res. 2019 Mar;118:18-26. doi: 10.1016/j.jpsychores.2019.01.002. Epub 2019 Jan 7.

PMID:
30782350
19.

PDL-1 Antibody Drug Conjugate for Selective Chemo-Guided Immune Modulation of Cancer.

Sau S, Petrovici A, Alsaab HO, Bhise K, Iyer AK.

Cancers (Basel). 2019 Feb 16;11(2). pii: E232. doi: 10.3390/cancers11020232.

20.

Preoperative MRI-radiomics features improve prediction of survival in glioblastoma patients over MGMT methylation status alone.

Tixier F, Um H, Bermudez D, Iyer A, Apte A, Graham MS, Nevel KS, Deasy JO, Young RJ, Veeraraghavan H.

Oncotarget. 2019 Jan 18;10(6):660-672. doi: 10.18632/oncotarget.26578. eCollection 2019 Jan 18.

21.

Learning clinical leadership.

Dovedi VK, Iyer A.

Clin Teach. 2019 Jun;16(3):290. doi: 10.1111/tct.13007. Epub 2019 Feb 11. No abstract available.

PMID:
30746852
22.

pH triggered and charge attracted nanogel for simultaneous evaluation of penetration and toxicity against skin cancer: In-vitro and ex-vivo study.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Int J Biol Macromol. 2019 May 1;128:740-751. doi: 10.1016/j.ijbiomac.2019.01.147. Epub 2019 Jan 27.

PMID:
30699336
23.

Computational Approaches to Photoelectrode Design through Molecular Functionalization for Enhanced Photoelectrochemical Water Splitting.

Iyer A, Kearney K, Ertekin E.

ChemSusChem. 2019 May 8;12(9):1858-1871. doi: 10.1002/cssc.201802514. Epub 2019 Mar 13. Review.

PMID:
30693653
24.

Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis.

Bansal M, He J, Peyton M, Kustagi M, Iyer A, Comb M, White M, Minna JD, Califano A.

PLoS One. 2019 Jan 7;14(1):e0208646. doi: 10.1371/journal.pone.0208646. eCollection 2019.

25.

Development of asialoglycoprotein receptor directed nanoparticles for selective delivery of curcumin derivative to hepatocellular carcinoma.

Yousef S, Alsaab HO, Sau S, Iyer AK.

Heliyon. 2018 Dec 22;4(12):e01071. doi: 10.1016/j.heliyon.2018.e01071. eCollection 2018 Dec.

26.

Neuroimmune Semaphorin 4A in Cancer Angiogenesis and Inflammation: A Promoter or a Suppressor?

Iyer AS, Chapoval SP.

Int J Mol Sci. 2018 Dec 30;20(1). pii: E124. doi: 10.3390/ijms20010124. Review.

27.

Long-term follow up data on difficult to treat intracranial arteriovenous malformations treated with the CyberKnife.

Gupta R, Moore JM, Amorin A, Appelboom G, Chaudhary N, Iyer A, Soltys SG, Gibbs IC, Steinberg GK, Chang SD.

J Clin Neurosci. 2019 Mar;61:120-123. doi: 10.1016/j.jocn.2018.10.109. Epub 2018 Dec 23.

PMID:
30587419
28.

JNK2 modulates the CD1d-dependent and -independent activation of iNKT cells.

Liu J, Gallo RM, Khan MA, Iyer AK, Kratzke IM, Brutkiewicz RR.

Eur J Immunol. 2019 Feb;49(2):255-265. doi: 10.1002/eji.201847755. Epub 2018 Dec 3.

PMID:
30467836
29.

pH Responsive 5-Fluorouracil Loaded Biocompatible Nanogels For Topical Chemotherapy of Aggressive Melanoma.

Sahu P, Kashaw SK, Sau S, Kushwah V, Jain S, Agrawal RK, Iyer AK.

Colloids Surf B Biointerfaces. 2019 Feb 1;174:232-245. doi: 10.1016/j.colsurfb.2018.11.018. Epub 2018 Nov 10.

PMID:
30465998
30.

Association of low income with pulmonary disease progression in smokers with and without chronic obstructive pulmonary disease.

Lowe KE, Make BJ, Crapo JD, Kinney GL, Hokanson JE, Kim V, Iyer AS, Bhatt SP, Hoth KF, Holm KE, Wise R, DeMeo D, Foreman MG, Stone TJ, Regan EA.

ERJ Open Res. 2018 Nov 12;4(4). pii: 00069-2018. doi: 10.1183/23120541.00069-2018. eCollection 2018 Oct.

31.

Persistent reduction in global longitudinal strain in the longer term after radiation therapy in patients with breast cancer.

Trivedi SJ, Choudhary P, Lo Q, Sritharan HP, Iyer A, Batumalai V, Delaney GP, Thomas L.

Radiother Oncol. 2019 Mar;132:148-154. doi: 10.1016/j.radonc.2018.10.023. Epub 2018 Nov 7.

PMID:
30414755
32.

Exploring the Role of Water Molecules in the Ligand Binding Domain of PDE4B and PDE4D: Virtual Screening Based Molecular Docking of Some Active Scaffolds.

Singh P, Mishra M, Agarwal S, Sau S, Iyer AK, Kashaw SK.

Curr Comput Aided Drug Des. 2019;15(4):334-366. doi: 10.2174/1573409914666181105153543.

PMID:
30394213
33.

Not Just Par for the Course: 73 Quaternary Germanides RE4 M2 XGe4 ( RE = La-Nd, Sm, Gd-Tm, Lu; M = Mn-Ni; X = Ag, Cd) and the Search for Intermetallics with Low Thermal Conductivity.

Zhang D, Oliynyk AO, Duarte GM, Iyer AK, Ghadbeigi L, Kauwe SK, Sparks TD, Mar A.

Inorg Chem. 2018 Nov 19;57(22):14249-14259. doi: 10.1021/acs.inorgchem.8b02279. Epub 2018 Oct 26.

PMID:
30365327
34.

Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents.

Kashaw SK, Agarwal S, Mishra M, Sau S, Iyer AK.

Curr Comput Aided Drug Des. 2019;15(1):55-66. doi: 10.2174/1573409914666181015150731.

PMID:
30324892
35.

Disruptive membrane interactions of alpha-synuclein aggregates.

Iyer A, Claessens MMAE.

Biochim Biophys Acta Proteins Proteom. 2019 May;1867(5):468-482. doi: 10.1016/j.bbapap.2018.10.006. Epub 2018 Oct 11. Review.

36.

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).

Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I.

Pharmaceutics. 2018 Oct 11;10(4). pii: E183. doi: 10.3390/pharmaceutics10040183.

37.

Pisces: an accurate and versatile variant caller for somatic and germline next-generation sequencing data.

Dunn T, Berry G, Emig-Agius D, Jiang Y, Lei S, Iyer A, Udar N, Chuang HY, Hegarty J, Dickover M, Klotzle B, Robbins J, Bibikova M, Peeters M, Strömberg M.

Bioinformatics. 2019 May 1;35(9):1579-1581. doi: 10.1093/bioinformatics/bty849.

38.

Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence.

Arena A, Zimmer TS, van Scheppingen J, Korotkov A, Anink JJ, Mühlebner A, Jansen FE, van Hecke W, Spliet WG, van Rijen PC, Vezzani A, Baayen JC, Idema S, Iyer AM, Perluigi M, Mills JD, van Vliet EA, Aronica E.

Brain Pathol. 2019 May;29(3):351-365. doi: 10.1111/bpa.12661. Epub 2018 Nov 20.

PMID:
30303592
39.

Addressing disrespect and abuse during childbirth in facilities.

Sen G, Reddy B, Iyer A, Heidari S.

Reprod Health Matters. 2018;26(53):1-5. doi: 10.1080/09688080.2018.1509970. No abstract available.

40.

Reviving old protecting group chemistry for site-selective peptide-protein conjugation.

Gunnoo SB, Iyer A, Vannecke W, Decoene KW, Hebbrecht T, Gettemans J, Laga M, Loverix S, Lasters I, Madder A.

Chem Commun (Camb). 2018 Oct 28;54(84):11929-11932. doi: 10.1039/c8cc06684a. Epub 2018 Oct 4.

PMID:
30285017
41.

Ionophores: Potential Use as Anticancer Drugs and Chemosensitizers.

Kaushik V, Yakisich JS, Kumar A, Azad N, Iyer AKV.

Cancers (Basel). 2018 Sep 27;10(10). pii: E360. doi: 10.3390/cancers10100360. Review.

42.

Immunotherapy and molecular role of T-cell in PD-1 antibody treated resectable lung cancer patients.

Sau S, Iyer AK.

J Thorac Dis. 2018 Aug;10(8):4682-4685. doi: 10.21037/jtd.2018.07.66. No abstract available.

43.

Life-Space mobility and clinical outcomes in COPD.

Iyer AS, Wells JM, Bhatt SP, Kirkpatrick DP, Sawyer P, Brown CJ, Allman RM, Bakitas MA, Dransfield MT.

Int J Chron Obstruct Pulmon Dis. 2018 Sep 4;13:2731-2738. doi: 10.2147/COPD.S170887. eCollection 2018.

44.

GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

Heinzman JT, Hoth KF, Cho MH, Sakornsakolpat P, Regan EA, Make BJ, Kinney GL, Wamboldt FS, Holm KE, Bormann N, Robles J, Kim V, Iyer AS, Silverman EK, Crapo JD, Han S, Potash JB, Shinozaki G; COPDGene Investigators.

J Affect Disord. 2019 Jan 15;243:16-22. doi: 10.1016/j.jad.2018.09.003. Epub 2018 Sep 7.

PMID:
30219690
45.

Conjugate addition from the excited state.

Iyer A, Ahuja S, Jockusch S, Ugrinov A, Sivaguru J.

Chem Commun (Camb). 2018 Sep 27;54(78):11021-11024. doi: 10.1039/c8cc05924a.

PMID:
30215437
46.

Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening.

Kaushik V, Yakisich JS, Way LF, Azad N, Iyer AKV.

J Cell Physiol. 2019 Apr;234(4):4445-4453. doi: 10.1002/jcp.27239. Epub 2018 Sep 7.

PMID:
30191978
47.

Beyond measurement: the drivers of disrespect and abuse in obstetric care.

Sen G, Reddy B, Iyer A.

Reprod Health Matters. 2018;26(53):6-18. doi: 10.1080/09688080.2018.1508173. Epub 2018 Sep 7.

48.

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages.

Alsaab HO, Sau S, Alzhrani RM, Cheriyan VT, Polin LA, Vaishampayan U, Rishi AK, Iyer AK.

Biomaterials. 2018 Nov;183:280-294. doi: 10.1016/j.biomaterials.2018.08.053. Epub 2018 Aug 30.

PMID:
30179778
49.

Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation.

Nabil G, Bhise K, Sau S, Atef M, El-Banna HA, Iyer AK.

Drug Discov Today. 2019 Feb;24(2):462-491. doi: 10.1016/j.drudis.2018.08.009. Epub 2018 Aug 16. Review.

PMID:
30121330
50.

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes.

Ramnath D, Irvine KM, Lukowski SW, Horsfall LU, Loh Z, Clouston AD, Patel PJ, Fagan KJ, Iyer A, Lampe G, Stow JL, Schroder K, Fairlie DP, Powell JE, Powell EE, Sweet MJ.

JCI Insight. 2018 Jul 26;3(14). pii: 120274. doi: 10.1172/jci.insight.120274. eCollection 2018 Jul 26.

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