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Items: 32

1.

Association of Body Fat and Risk of Breast Cancer in Postmenopausal Women With Normal Body Mass Index: A Secondary Analysis of a Randomized Clinical Trial and Observational Study.

Iyengar NM, Arthur R, Manson JE, Chlebowski RT, Kroenke CH, Peterson L, Cheng TD, Feliciano EC, Lane D, Luo J, Nassir R, Pan K, Wassertheil-Smoller S, Kamensky V, Rohan TE, Dannenberg AJ.

JAMA Oncol. 2018 Dec 6. doi: 10.1001/jamaoncol.2018.5327. [Epub ahead of print]

PMID:
30520976
2.

Prostaglandin E2down-regulates sirtuin 1 (SIRT1) leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.

Subbaramaiah K, Iyengar NM, Morrow M, Elemento O, Zhou XK, Dannenberg AJ.

J Biol Chem. 2018 Nov 8. pii: jbc.RA118.005866. doi: 10.1074/jbc.RA118.005866. [Epub ahead of print]

3.

Obesity-associated breast inflammation among Hispanic/Latina breast cancer patients.

Greenlee H, Shi Z, Hibshoosh H, Giri DD, Ahmed A, Williams S, Falcone DJ, Winston LA, Zhou XK, Hudis CA, Hershman DL, Dannenberg AJ, Iyengar NM.

Cancer Prev Res (Phila). 2018 Nov 7. pii: canprevres.0207.2018. doi: 10.1158/1940-6207.CAPR-18-0207. [Epub ahead of print]

PMID:
30404870
4.

FGFR1 underlies obesity-associated progression of estrogen receptor-positive breast cancer after estrogen deprivation.

Wellberg EA, Kabos P, Gillen AE, Jacobsen BM, Brechbuhl HM, Johnson SJ, Rudolph MC, Edgerton SM, Thor AD, Anderson SM, Elias A, Zhou XK, Iyengar NM, Morrow M, Falcone DJ, El-Hely O, Dannenberg AJ, Sartorius CA, MacLean PS.

JCI Insight. 2018 Jul 25;3(14). pii: 120594. doi: 10.1172/jci.insight.120594. [Epub ahead of print]

5.

Efficacy of Exercise Therapy on Cardiorespiratory Fitness in Patients With Cancer: A Systematic Review and Meta-Analysis.

Scott JM, Zabor EC, Schwitzer E, Koelwyn GJ, Adams SC, Nilsen TS, Moskowitz CS, Matsoukas K, Iyengar NM, Dang CT, Jones LW.

J Clin Oncol. 2018 Aug 1;36(22):2297-2305. doi: 10.1200/JCO.2017.77.5809. Epub 2018 Jun 12.

PMID:
29894274
6.

The Impact of Obesity on Breast Cancer.

Argolo DF, Hudis CA, Iyengar NM.

Curr Oncol Rep. 2018 Apr 11;20(6):47. doi: 10.1007/s11912-018-0688-8. Review.

PMID:
29644507
7.

Feasibility, safety, and efficacy of aerobic training in pretreated patients with metastatic breast cancer: A randomized controlled trial.

Scott JM, Iyengar NM, Nilsen TS, Michalski M, Thomas SM, Herndon J 2nd, Sasso J, Yu A, Chandarlapaty S, Dang CT, Comen EA, Dickler MN, Peppercorn JM, Jones LW.

Cancer. 2018 Jun 15;124(12):2552-2560. doi: 10.1002/cncr.31368. Epub 2018 Apr 6.

PMID:
29624641
8.

Exercise Implementation in Oncology: One Size Does Not Fit All.

Adams SC, Iyengar NM, Scott JM, Jones LW.

J Clin Oncol. 2018 Mar 20;36(9):925-926. doi: 10.1200/JCO.2017.76.2906. Epub 2018 Jan 26. No abstract available.

PMID:
29373093
9.

Effects of Rapid Weight Loss on Systemic and Adipose Tissue Inflammation and Metabolism in Obese Postmenopausal Women.

Alemán JO, Iyengar NM, Walker JM, Milne GL, Da Rosa JC, Liang Y, Giri DD, Zhou XK, Pollak MN, Hudis CA, Breslow JL, Holt PR, Dannenberg AJ.

J Endocr Soc. 2017 Apr 25;1(6):625-637. doi: 10.1210/js.2017-00020. eCollection 2017 Jun 1.

10.

Adiposity, Inflammation, and Breast Cancer Pathogenesis in Asian Women.

Iyengar NM, Chen IC, Zhou XK, Giri DD, Falcone DJ, Winston LA, Wang H, Williams S, Lu YS, Hsueh TH, Cheng AL, Hudis CA, Lin CH, Dannenberg AJ.

Cancer Prev Res (Phila). 2018 Apr;11(4):227-236. doi: 10.1158/1940-6207.CAPR-17-0283. Epub 2017 Dec 8.

PMID:
29222346
11.

Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity-breast cancer link.

Zahid H, Subbaramaiah K, Iyengar NM, Zhou XK, Chen IC, Bhardwaj P, Gucalp A, Morrow M, Hudis CA, Dannenberg AJ, Brown KA.

Int J Obes (Lond). 2018 Apr;42(4):711-720. doi: 10.1038/ijo.2017.273. Epub 2017 Nov 6.

12.

PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs.

Mattox AK, Lee J, Westra WH, Pierce RH, Ghossein R, Faquin WC, Diefenbach TJ, Morris LG, Lin DT, Wirth LJ, Lefranc-Torres A, Ishida E, Chakravarty PD, Johnson L, Zeng YC, Chen H, Poznansky MC, Iyengar NM, Pai SI.

Cancer Res. 2017 Nov 15;77(22):6365-6374. doi: 10.1158/0008-5472.CAN-16-3453. Epub 2017 Sep 25.

13.

Periprostatic adipose inflammation is associated with high-grade prostate cancer.

Gucalp A, Iyengar NM, Zhou XK, Giri DD, Falcone DJ, Wang H, Williams S, Krasne MD, Yaghnam I, Kunzel B, Morris PG, Jones LW, Pollak M, Laudone VP, Hudis CA, Scher HI, Scardino PT, Eastham JA, Dannenberg AJ.

Prostate Cancer Prostatic Dis. 2017 Dec;20(4):418-423. doi: 10.1038/pcan.2017.31. Epub 2017 Jun 27.

14.

Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers.

Brown KA, Iyengar NM, Zhou XK, Gucalp A, Subbaramaiah K, Wang H, Giri DD, Morrow M, Falcone DJ, Wendel NK, Winston LA, Pollak M, Dierickx A, Hudis CA, Dannenberg AJ.

J Clin Endocrinol Metab. 2017 May 1;102(5):1692-1701. doi: 10.1210/jc.2016-3606.

15.

Metabolic Obesity, Adipose Inflammation and Elevated Breast Aromatase in Women with Normal Body Mass Index.

Iyengar NM, Brown KA, Zhou XK, Gucalp A, Subbaramaiah K, Giri DD, Zahid H, Bhardwaj P, Wendel NK, Falcone DJ, Wang H, Williams S, Pollak M, Morrow M, Hudis CA, Dannenberg AJ.

Cancer Prev Res (Phila). 2017 Apr;10(4):235-243. doi: 10.1158/1940-6207.CAPR-16-0314. Epub 2017 Mar 7.

16.

Docosahexaenoic Acid Supplementation is Not Anti-Inflammatory in Adipose Tissue of Healthy Obese Postmenopausal Women.

Holt PR, Alemán JO, Walker JM, Jiang CS, Liang Y, de Rosa JC, Giri DD, Iyengar NM, Milne GL, Hudis CA, Breslow JL.

Int J Nutr. 2017;1(4):31-49. doi: 10.14302/issn.2379-7835.ijn-17-1636. Epub 2017 Jul 21.

17.

Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation.

Iyengar NM, Gucalp A, Dannenberg AJ, Hudis CA.

J Clin Oncol. 2016 Dec 10;34(35):4270-4276. Epub 2016 Nov 7. Review.

18.

White adipose tissue inflammation and cancer-specific survival in patients with squamous cell carcinoma of the oral tongue.

Iyengar NM, Ghossein RA, Morris LG, Zhou XK, Kochhar A, Morris PG, Pfister DG, Patel SG, Boyle JO, Hudis CA, Dannenberg AJ.

Cancer. 2016 Dec 15;122(24):3794-3802. doi: 10.1002/cncr.30251. Epub 2016 Aug 10.

19.

Weekly paclitaxel with trastuzumab and pertuzumab in patients with HER2-overexpressing metastatic breast cancer: overall survival and updated progression-free survival results from a phase II study.

Smyth LM, Iyengar NM, Chen MF, Popper SM, Patil S, Wasserheit-Lieblich C, Argolo DF, Singh JC, Chandarlapaty S, Sugarman SM, Comen EA, Drullinsky PR, Traina TA, Troso-Sandoval T, Baselga J, Norton L, Hudis CA, Dang CT.

Breast Cancer Res Treat. 2016 Jul;158(1):91-97. doi: 10.1007/s10549-016-3851-7. Epub 2016 Jun 15.

20.

Erratum to: Obesity and Cancer: Concepts and Challenges.

Argolo DF, Iyengar NM, Hudis CA.

Indian J Surg Oncol. 2015 Dec;6(4):399. doi: 10.1007/s13193-015-0484-y. Epub 2015 Dec 22.

21.

Obesity and Cancer: Concepts and Challenges.

Argolo DF, Iyengar NM, Hudis CA.

Indian J Surg Oncol. 2015 Dec;6(4):390-8. doi: 10.1007/s13193-015-0483-z. Epub 2015 Nov 23. Erratum in: Indian J Surg Oncol. 2015 Dec;6(4):399.

22.

Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression.

Gucalp A, Iyengar NM, Hudis CA, Dannenberg AJ.

Semin Oncol. 2016 Feb;43(1):154-160. doi: 10.1053/j.seminoncol.2015.09.012. Epub 2015 Sep 8. Review.

23.

Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer.

Iyengar NM, Zhou XK, Gucalp A, Morris PG, Howe LR, Giri DD, Morrow M, Wang H, Pollak M, Jones LW, Hudis CA, Dannenberg AJ.

Clin Cancer Res. 2016 May 1;22(9):2283-9. doi: 10.1158/1078-0432.CCR-15-2239. Epub 2015 Dec 28.

24.

A Pilot Study of Dose-Dense Paclitaxel With Trastuzumab and Lapatinib for Node-negative HER2-Overexpressed Breast Cancer.

Iyengar NM, Fornier MN, Sugarman SM, Theodoulou M, Troso-Sandoval TA, D'Andrea GM, Drullinsky PR, Gajria D, Goldfarb SB, Comen EA, Lake DE, Modi S, Traina TA, Lacouture ME, Chen MF, Patil S, Baselga J, Norton L, Hudis CA, Dang CT.

Clin Breast Cancer. 2016 Apr;16(2):87-94. doi: 10.1016/j.clbc.2015.09.009. Epub 2015 Sep 25.

25.

Menopause is a determinant of breast adipose inflammation.

Iyengar NM, Morris PG, Zhou XK, Gucalp A, Giri D, Harbus MD, Falcone DJ, Krasne MD, Vahdat LT, Subbaramaiah K, Morrow M, Hudis CA, Dannenberg AJ.

Cancer Prev Res (Phila). 2015 May;8(5):349-58. doi: 10.1158/1940-6207.CAPR-14-0243. Epub 2015 Feb 26.

26.

Obesity and cancer: local and systemic mechanisms.

Iyengar NM, Hudis CA, Dannenberg AJ.

Annu Rev Med. 2015;66:297-309. doi: 10.1146/annurev-med-050913-022228. Review.

PMID:
25587653
27.

Impact of obesity on the survival of patients with early-stage squamous cell carcinoma of the oral tongue.

Iyengar NM, Kochhar A, Morris PG, Morris LG, Zhou XK, Ghossein RA, Pino A, Fury MG, Pfister DG, Patel SG, Boyle JO, Hudis CA, Dannenberg AJ.

Cancer. 2014 Apr 1;120(7):983-91. doi: 10.1002/cncr.28532. Epub 2014 Jan 21.

28.

Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.

Jain N, Curran E, Iyengar NM, Diaz-Flores E, Kunnavakkam R, Popplewell L, Kirschbaum MH, Karrison T, Erba HP, Green M, Poire X, Koval G, Shannon K, Reddy PL, Joseph L, Atallah EL, Dy P, Thomas SP, Smith SE, Doyle LA, Stadler WM, Larson RA, Stock W, Odenike O.

Clin Cancer Res. 2014 Jan 15;20(2):490-8. doi: 10.1158/1078-0432.CCR-13-1311. Epub 2013 Oct 31.

29.

Omega-3 fatty acids for the prevention of breast cancer: an update and state of the science.

Iyengar NM, Hudis CA, Gucalp A.

Curr Breast Cancer Rep. 2013 Sep 1;5(3):247-254.

30.

Long-term cardiac safety and outcomes of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel and trastuzumab with and without lapatinib in patients with early breast cancer.

Morris PG, Iyengar NM, Patil S, Chen C, Abbruzzi A, Lehman R, Steingart R, Oeffinger KC, Lin N, Moy B, Come SE, Winer EP, Norton L, Hudis CA, Dang CT.

Cancer. 2013 Nov 15;119(22):3943-51. doi: 10.1002/cncr.28284. Epub 2013 Aug 26.

31.

Obesity and inflammation: new insights into breast cancer development and progression.

Iyengar NM, Hudis CA, Dannenberg AJ.

Am Soc Clin Oncol Educ Book. 2013:46-51. doi: 10.1200/EdBook_AM.2013.33.46. Review.

32.

Identifying the challenges of biomarkers that predict response to HER2-directed therapies.

Iyengar NM, Morris PG.

Expert Opin Pharmacother. 2013 Aug;14(11):1437-40. doi: 10.1517/14656566.2013.803069. Epub 2013 May 27.

PMID:
23705932

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