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Items: 16


Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.

Desta Z, Gammal RS, Gong L, Whirl-Carrillo M, Gaur AH, Sukasem C, Hockings J, Myers A, Swart M, Tyndale RF, Masimirembwa C, Iwuchukwu OF, Chirwa S, Lennox J, Gaedigk A, Klein TE, Haas DW.

Clin Pharmacol Ther. 2019 Oct;106(4):726-733. doi: 10.1002/cpt.1477. Epub 2019 Jul 5.


Using Personalized Medicine in the Management of Diabetes Mellitus.

Elk N, Iwuchukwu OF.

Pharmacotherapy. 2017 Sep;37(9):1131-1149. doi: 10.1002/phar.1976. Epub 2017 Aug 15. Review.


Genetic determinants of variability in warfarin response after the dose-titration phase.

Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM.

Pharmacogenet Genomics. 2016 Nov;26(11):510-516.


Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.

Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2016 Apr;99(4):363-9. doi: 10.1002/cpt.269. Epub 2015 Nov 9. Review.


Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins.

Wei WQ, Feng Q, Weeke P, Bush W, Waitara MS, Iwuchukwu OF, Roden DM, Wilke RA, Stein CM, Denny JC.

AMIA Jt Summits Transl Sci Proc. 2014 Apr 7;2014:112-9. eCollection 2014.


Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting.

Iwuchukwu OF, Feng Q, Wei WQ, Jiang L, Jiang M, Xu H, Denny JC, Wilke RA, Krauss RM, Roden DM, Stein CM.

Pharmacogenomics. 2014 Nov;15(14):1739-1747.


Case study 1. Practical considerations with experimental design and interpretation.

Barr JT, Flora DR, Iwuchukwu OF.

Methods Mol Biol. 2014;1113:419-29. doi: 10.1007/978-1-62703-758-7_18.


Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, Crews KR, Scott SA, Wadelius M, Swen JJ, Tyndale RF, Stein CM, Roden D, Relling MV, Williams MS, Johnson SG.

Curr Drug Metab. 2014 Feb;15(2):209-17.


Characterization of statin dose response in electronic medical records.

Wei WQ, Feng Q, Jiang L, Waitara MS, Iwuchukwu OF, Roden DM, Jiang M, Xu H, Krauss RM, Rotter JI, Nickerson DA, Davis RL, Berg RL, Peissig PL, McCarty CA, Wilke RA, Denny JC.

Clin Pharmacol Ther. 2014 Mar;95(3):331-8. doi: 10.1038/clpt.2013.202. Epub 2013 Oct 4.


In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide.

Sharan S, Iwuchukwu OF, Canney DJ, Zimmerman CL, Nagar S.

Drug Metab Dispos. 2012 Oct;40(10):1993-2001. doi: 10.1124/dmd.112.046417. Epub 2012 Jul 17. Erratum in: Drug Metab Dispos. 2012 Dec;40(12):2382.


Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies.

Iwuchukwu OF, Sharan S, Canney DJ, Nagar S.

J Pharm Biomed Anal. 2012 Apr 7;63:1-8. doi: 10.1016/j.jpba.2011.12.006. Epub 2011 Dec 16.


Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.

Iwuchukwu OF, Tallarida RJ, Nagar S.

Life Sci. 2011 Jun 6;88(23-24):1047-54. doi: 10.1016/j.lfs.2011.03.016. Epub 2011 Apr 3.


Cis-resveratrol glucuronidation kinetics in human and recombinant UGT1A sources.

Iwuchukwu OF, Nagar S.

Xenobiotica. 2010 Feb;40(2):102-8. doi: 10.3109/00498250903406754.


Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation.

Iwuchukwu OF, Ajetunmobi J, Ung D, Nagar S.

Drug Metab Dispos. 2009 Aug;37(8):1726-32. doi: 10.1124/dmd.109.027391. Epub 2009 Apr 30.


Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms.

Argikar UA, Iwuchukwu OF, Nagar S.

Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):879-94. doi: 10.1517/17425255.4.7.879 . Review.


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