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Items: 1 to 20 of 104

1.

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD.

Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR.

Blood. 2019 Nov 7;134(19):1670-1682. doi: 10.1182/blood.2019001950.

PMID:
31533918
2.

Photocleavable Cadherin Inhibits Cell-to-Cell Mechanotransduction by Light.

Endo M, Iwawaki T, Yoshimura H, Ozawa T.

ACS Chem Biol. 2019 Oct 18;14(10):2206-2214. doi: 10.1021/acschembio.9b00460. Epub 2019 Sep 20.

PMID:
31503442
3.

Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress.

Sekiguchi A, Motegi SI, Fujiwara C, Yamazaki S, Inoue Y, Uchiyama A, Akai R, Iwawaki T, Ishikawa O.

J Dermatol Sci. 2019 Oct;96(1):8-17. doi: 10.1016/j.jdermsci.2019.08.004. Epub 2019 Aug 16.

PMID:
31447184
4.

MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.

Takeda K, Nagashima S, Shiiba I, Uda A, Tokuyama T, Ito N, Fukuda T, Matsushita N, Ishido S, Iwawaki T, Uehara T, Inatome R, Yanagi S.

EMBO J. 2019 Aug 1;38(15):e100999. doi: 10.15252/embj.2018100999. Epub 2019 Jun 13.

5.

Zinc deficiency exacerbates pressure ulcers by increasing oxidative stress and ATP in the skin.

Nakamura H, Sekiguchi A, Ogawa Y, Kawamura T, Akai R, Iwawaki T, Makiguchi T, Yokoo S, Ishikawa O, Motegi SI.

J Dermatol Sci. 2019 Aug;95(2):62-69. doi: 10.1016/j.jdermsci.2019.07.004. Epub 2019 Jul 12.

PMID:
31327530
6.

IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.

Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR.

Science. 2019 Jul 19;365(6450). pii: eaau6499. doi: 10.1126/science.aau6499.

PMID:
31320508
7.

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.

Suzuki T, Muramatsu A, Saito R, Iso T, Shibata T, Kuwata K, Kawaguchi SI, Iwawaki T, Adachi S, Suda H, Morita M, Uchida K, Baird L, Yamamoto M.

Cell Rep. 2019 Jul 16;28(3):746-758.e4. doi: 10.1016/j.celrep.2019.06.047.

8.

ERdj5 in Innate Immune Cells Is a Crucial Factor for the Mucosal Adjuvanticity of Cholera Toxin.

Kim MS, Yi EJ, Kim YI, Kim SH, Jung YS, Kim SR, Iwawaki T, Ko HJ, Chang SY.

Front Immunol. 2019 Jun 4;10:1249. doi: 10.3389/fimmu.2019.01249. eCollection 2019.

9.

A ten-inch manipulator (TIM) based fast-electron spectrometer with multiple viewing angles (OU-ESM).

Habara H, Iwawaki T, Gong T, Wei MS, Ivancic ST, Theobald W, Krauland CM, Zhang S, Fiksel G, Tanaka KA.

Rev Sci Instrum. 2019 Jun;90(6):063501. doi: 10.1063/1.5088529.

PMID:
31255022
10.

Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients.

Apostolou E, Moustardas P, Iwawaki T, Tzioufas AG, Spyrou G.

Front Immunol. 2019 Mar 22;10:506. doi: 10.3389/fimmu.2019.00506. eCollection 2019.

11.

Correction: IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.

Tsuchiya Y, Saito M, Kadokura H, Miyazaki JI, Tashiro F, Imagawa Y, Iwawaki T, Kohno K.

J Cell Biol. 2019 May 6;218(5):1764. doi: 10.1083/jcb.20170714303252019c. Epub 2019 Mar 29. No abstract available.

12.

Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells.

Liu L, Zhao M, Jin X, Ney G, Yang KB, Peng F, Cao J, Iwawaki T, Del Valle J, Chen X, Li Q.

Nat Cell Biol. 2019 Mar;21(3):328-337. doi: 10.1038/s41556-019-0285-6. Epub 2019 Feb 18.

13.

IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming.

Medel B, Costoya C, Fernandez D, Pereda C, Lladser A, Sauma D, Pacheco R, Iwawaki T, Salazar-Onfray F, Osorio F.

Front Immunol. 2019 Jan 4;9:3050. doi: 10.3389/fimmu.2018.03050. eCollection 2018.

14.

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.

Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB.

Nat Commun. 2018 Dec 17;9(1):5340. doi: 10.1038/s41467-018-07758-x.

15.

Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication.

Antoniou AN, Lenart I, Kriston-Vizi J, Iwawaki T, Turmaine M, McHugh K, Ali S, Blake N, Bowness P, Bajaj-Elliott M, Gould K, Nesbeth D, Powis SJ.

Ann Rheum Dis. 2019 Jan;78(1):74-82. doi: 10.1136/annrheumdis-2018-213532. Epub 2018 Oct 24.

16.

Publisher Correction: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0186-0.

PMID:
30089843
17.

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Erratum in: Nat Cell Biol. 2018 Oct;20(10):1228.

PMID:
30013108
18.

Activation of Host IRE1α-Dependent Signaling Axis Contributes the Intracellular Parasitism of Brucella melitensis.

Pandey A, Lin F, Cabello AL, da Costa LF, Feng X, Feng HQ, Zhang MZ, Iwawaki T, Rice-Ficht A, Ficht TA, de Figueiredo P, Qin QM.

Front Cell Infect Microbiol. 2018 Apr 20;8:103. doi: 10.3389/fcimb.2018.00103. eCollection 2018.

19.

IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.

Tsuchiya Y, Saito M, Kadokura H, Miyazaki JI, Tashiro F, Imagawa Y, Iwawaki T, Kohno K.

J Cell Biol. 2018 Apr 2;217(4):1287-1301. doi: 10.1083/jcb.201707143. Epub 2018 Mar 5. Erratum in: J Cell Biol. 2019 Mar 29;:.

20.

ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response.

Chapple RH, Hu T, Tseng YJ, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D.

Elife. 2018 Feb 16;7. pii: e31159. doi: 10.7554/eLife.31159.

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