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Xanthan gum and locust bean gum gel supports in vitro development of porcine oocytes derived from early antral follicles.

Munakata Y, Sugimoto A, Shirasuna K, Kuwayama T, Iwata H.

J Reprod Dev. 2019 Oct 6. doi: 10.1262/jrd.2019-074. [Epub ahead of print]


Proton Beam Therapy for Histologically or Clinically Diagnosed Stage I Non-small Cell Lung Cancer (NSCLC): The First Nationwide Retrospective Study in Japan.

Ohnishi K, Nakamura N, Harada H, Tokumaru S, Wada H, Arimura T, Iwata H, Sato Y, Sekino Y, Tamamura H, Mizoe JE, Ogino T, Ishikawa H, Kikuchi Y, Okimoto T, Murayama S, Akimoto T, Sakurai H.

Int J Radiat Oncol Biol Phys. 2019 Sep 30. pii: S0360-3016(19)33837-4. doi: 10.1016/j.ijrobp.2019.09.013. [Epub ahead of print]


Enzalutamide versus flutamide for castration-resistant prostate cancer after combined androgen blockade therapy with bicalutamide: the OCUU-CRPC study.

Iguchi T, Tamada S, Kato M, Yasuda S, Machida Y, Ohmachi T, Ishii K, Iwata H, Yamamoto S, Kanamaru T, Morimoto K, Hase T, Tashiro K, Harimoto K, Deguchi T, Adachi T, Iwamoto K, Takegaki Y, Nakatani T.

Int J Clin Oncol. 2019 Sep 28. doi: 10.1007/s10147-019-01554-3. [Epub ahead of print]


CT and MRI characteristics for differentiating mediastinal Müllerian cysts from bronchogenic cysts.

Kawaguchi M, Kato H, Hara A, Suzui N, Tomita H, Miyazaki T, Iwata H, Matsuo M.

Clin Radiol. 2019 Sep 21. pii: S0009-9260(19)30525-2. doi: 10.1016/j.crad.2019.08.013. [Epub ahead of print]


Patient-reported outcomes and objective assessments with arm measurement and bioimpedance analysis for lymphedema among breast cancer survivors.

Terada M, Yoshimura A, Sawaki M, Hattori M, Naomi G, Kotani H, Adachi Y, Iwase M, Kataoka A, Sugino K, Mori M, Horisawa N, Ozaki Y, Iwata H.

Breast Cancer Res Treat. 2019 Sep 18. doi: 10.1007/s10549-019-05443-1. [Epub ahead of print]


Distinct gene expression profiles between primary breast cancers and brain metastases from pair-matched samples.

Iwamoto T, Niikura N, Ogiya R, Yasojima H, Watanabe KI, Kanbayashi C, Tsuneizumi M, Matsui A, Fujisawa T, Iwasa T, Shien T, Saji S, Masuda N, Iwata H.

Sci Rep. 2019 Sep 16;9(1):13343. doi: 10.1038/s41598-019-50099-y.


Experiences of transition to motherhood among pregnant women following assisted reproductive technology: a systematic review protocol of qualitative evidence.

Maehara K, Iwata H, Kosaka M, Kimura K, Mori E.

JBI Database System Rev Implement Rep. 2019 Sep 12. doi: 10.11124/JBISRIR-D-19-00071. [Epub ahead of print]


Mechanism of palmitic acid-induced deterioration of in vitro development of porcine oocytes and granulosa cells.

Shibahara H, Ishiguro A, Inoue Y, Koumei S, Kuwayama T, Iwata H.

Theriogenology. 2019 Sep 6;141:54-61. doi: 10.1016/j.theriogenology.2019.09.006. [Epub ahead of print]


The expression of cell adhesion molecule 1 and its splicing variants in Sézary cells and cell lines from cutaneous T-cell lymphoma.

Yamaguchi M, Morizane S, Hamada T, Miyake T, Sugaya M, Iwata H, Fujii K, Haramoto-Shiratsuki R, Nakagawa Y, Miura M, Ohshima K, Morishita K, Takahashi T, Imada M, Okada K, Uehara J, Sowa-Osako J, Iwatsuki K.

J Dermatol. 2019 Sep 12. doi: 10.1111/1346-8138.15078. [Epub ahead of print]


Oncolytic activity of HF10 in head and neck squamous cell carcinomas.

Esaki S, Goshima F, Ozaki H, Takano G, Hatano Y, Kawakita D, Ijichi K, Watanabe T, Sato Y, Murata T, Iwata H, Shibamoto Y, Murakami S, Nishiyama Y, Kimura H.

Cancer Gene Ther. 2019 Sep 3. doi: 10.1038/s41417-019-0129-3. [Epub ahead of print]


Mitochondrial cell-free DNA secreted from porcine granulosa cells.

Kansaku K, Munakata Y, Shirasuna K, Kuwayama T, Iwata H.

Zygote. 2019 Oct;27(5):272-278. doi: 10.1017/S096719941900025X. Epub 2019 Aug 14.


Establishment of human trophoblast stem cells from human induced pluripotent stem cell-derived cystic cells under micromesh culture.

Li Z, Kurosawa O, Iwata H.

Stem Cell Res Ther. 2019 Aug 7;10(1):245. doi: 10.1186/s13287-019-1339-1.


Preeclamptic patient-derived circulating cell-free DNA activates the production of inflammatory cytokines via toll-like receptor 9 signalling in the human placenta.

Ozeki A, Tani K, Takahashi H, Suzuki H, Nagayama S, Hirashima C, Iwata H, Kuwayama T, Ohkuchi A, Shirasuna K.

J Hypertens. 2019 Aug 2. doi: 10.1097/HJH.0000000000002208. [Epub ahead of print]


The transfer of parthenogenetic embryos following artificial insemination in cows can enhance pregnancy recognition via the secretion of interferon tau.

Funeshima N, Noguchi T, Onizawa Y, Yaginuma H, Miyamura M, Tsuchiya H, Iwata H, Kuwayama T, Hamano S, Shirasuna K.

J Reprod Dev. 2019 Aug 3. doi: 10.1262/jrd.2019-026. [Epub ahead of print]


Identification of Spring Coefficient for Heel Rocker Function Support Based on Estimated Dorsiflexion Torque.

Hong JC, Hayashi Y, Suzuki S, Fukushima Y, Yasuda K, Ohashi H, Iwata H.

IEEE Int Conf Rehabil Robot. 2019 Jun;2019:355-359. doi: 10.1109/ICORR.2019.8779393.


Factors affecting the accuracy of respiratory tracking of the image-guided robotic radiosurgery system.

Inoue M, Okawa K, Taguchi J, Hirota Y, Yanagiya Y, Kikuchi C, Iwabuchi M, Murai T, Iwata H, Shiomi H, Koike I, Tatewaki K, Ohta S.

Jpn J Radiol. 2019 Oct;37(10):727-734. doi: 10.1007/s11604-019-00859-7. Epub 2019 Jul 31.


ASO Author Reflections: The Strengths and Weaknesses of Intraoperative Radiotherapy for Early Breast Cancer and Ipsilateral Tumor Recurrence.

Sawaki M, Kodaira T, Iwata H.

Ann Surg Oncol. 2019 Jul 29. doi: 10.1245/s10434-019-07658-4. [Epub ahead of print] No abstract available.


Clinical impact of complex percutaneous coronary intervention in patients with coronary artery disease.

Endo H, Dohi T, Miyauchi K, Takahashi D, Funamizu T, Shitara J, Wada H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Daida H.

Cardiovasc Interv Ther. 2019 Jul 26. doi: 10.1007/s12928-019-00608-7. [Epub ahead of print]


Presence of small residual malignant lesions in pathologic complete response after neo-adjuvant chemotherapy in patients with breast cancer.

Iwase M, Hattori M, Sawaki M, Yoshimura A, Kotani H, Gondo N, Adachi Y, Kataoka A, Onishi S, Sugino K, Horisawa N, Mori M, Terada M, Iwata H.

Breast J. 2019 Jul 18. doi: 10.1111/tbj.13473. [Epub ahead of print] No abstract available.


Follicular factors determining the developmental competence of porcine oocyte.

Shibahara H, Ishiguro A, Shirasuna K, Kuwayama T, Iwata H.

Reprod Med Biol. 2019 Apr 10;18(3):256-262. doi: 10.1002/rmb2.12269. eCollection 2019 Jul.


Clinical indicators and coronary angiographic features of expansive arterial remodelling in patients with abdominal aortic aneurysms.

Endo H, Dohi T, Dohi S, Wada H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Yamamoto T, Miyauchi K, Amano A, Daida H.

PLoS One. 2019 Jul 16;14(7):e0219730. doi: 10.1371/journal.pone.0219730. eCollection 2019.


Expression of precipitating factors of pruritus found in humans in an imiquimod-induced psoriasis mouse model.

Oishi N, Iwata H, Kambe N, Kobayashi N, Fujimoto K, Sato H, Hisaka A, Ueno K, Yamaura K.

Heliyon. 2019 Jun 20;5(6):e01981. doi: 10.1016/j.heliyon.2019.e01981. eCollection 2019 Jun.


Immune Reaction to Type XVII Collagen Induces Intramolecular and Intermolecular Epitope Spreading in Experimental Bullous Pemphigoid Models.

Ujiie H, Yoshimoto N, Natsuga K, Muramatsu K, Iwata H, Nishie W, Shimizu H.

Front Immunol. 2019 Jun 19;10:1410. doi: 10.3389/fimmu.2019.01410. eCollection 2019.


A Novel Nutritional Index Serves as A Useful Prognostic Indicator in Cardiac Critical Patients Requiring Mechanical Circulatory Support.

Minami-Takano A, Iwata H, Miyosawa K, Kubota K, Kimura A, Osawa S, Shitara M, Okazaki S, Suwa S, Miyauchi K, Sumiyoshi M, Amano A, Daida H.

Nutrients. 2019 Jun 24;11(6). pii: E1420. doi: 10.3390/nu11061420.


S100A8, which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells.

Nakamura Y, Iwata H, Kuwayama T, Shirasuna K.

Am J Reprod Immunol. 2019 Sep;82(3):e13163. doi: 10.1111/aji.13163. Epub 2019 Jul 10.


In vitro assessment of effects of persistent organic pollutants on the transactivation of estrogen receptor α and β (ERα and ERβ) from the Baikal seal (Pusa sibirica).

Yoshinouchi Y, Shimizu S, Lee JS, Hirano M, Suzuki KT, Kim EY, Iwata H.

Ecotoxicol Environ Saf. 2019 Oct 15;181:463-471. doi: 10.1016/j.ecoenv.2019.06.033. Epub 2019 Jun 19.


A survey on awareness of the "finger-tip unit" and medication guidance for the use of topical steroids among community pharmacists.

Oishi N, Iwata H, Kobayashi N, Fujimoto K, Yamaura K.

Drug Discov Ther. 2019 Jul 22;13(3):128-132. doi: 10.5582/ddt.2019.01007. Epub 2019 Jun 14.


In vitro and in silico AHR assays for assessing the risk of heavy oil-derived polycyclic aromatic hydrocarbons in fish.

Bak SM, Nakata H, Koh DH, Yoo J, Iwata H, Kim EY.

Ecotoxicol Environ Saf. 2019 Oct 15;181:214-223. doi: 10.1016/j.ecoenv.2019.06.008. Epub 2019 Jun 10.


Targeted metabolome analysis of the dog brain exposed to PCBs suggests inhibition of oxidative phosphorylation by hydroxylated PCBs.

Nomiyama K, Eguchi A, Takaguchi K, Yoo J, Mizukawa H, Oshihoi T, Tanabe S, Iwata H.

Toxicol Appl Pharmacol. 2019 Aug 15;377:114620. doi: 10.1016/j.taap.2019.114620. Epub 2019 Jun 10.


Preoperative screening for nasal carriage of methicillin-resistant Staphylococcus aureus in patients undergoing general thoracic surgery.

Mizuno Y, Shirahashi K, Yamamoto H, Matsumoto M, Miyamoto Y, Komuro H, Doi K, Iwata H.

J Rural Med. 2019 May;14(1):73-77. doi: 10.2185/jrm.2987. Epub 2019 May 30.


Gut microbiota development of preterm infants hospitalised in intensive care units.

Tauchi H, Yahagi K, Yamauchi T, Hara T, Yamaoka R, Tsukuda N, Watakabe Y, Tajima S, Ochi F, Iwata H, Ohta M, Ishii E, Matsumoto S, Matsuki T.

Benef Microbes. 2019 Jun 9:1-12. doi: 10.3920/BM2019.0003. [Epub ahead of print]


Correction to: Neutropenia management with palbociclib in Japanese patients with advanced breast cancer.

Masuda N, Mukai H, Inoue K, Rai Y, Ohno S, Mori Y, Hashigaki S, Muramatsu Y, Umeyama Y, Iwata H, Toi M.

Breast Cancer. 2019 Sep;26(5):651. doi: 10.1007/s12282-019-00984-1.


Impact of serum 1,5-anhydro-D-glucitol level on the prediction of severe coronary artery calcification: an intravascular ultrasound study.

Wada H, Dohi T, Miyauchi K, Takahashi N, Endo H, Kato Y, Ogita M, Okai I, Iwata H, Okazaki S, Isoda K, Shimada K, Suwa S, Daida H.

Cardiovasc Diabetol. 2019 Jun 3;18(1):69. doi: 10.1186/s12933-019-0878-1.


A single-arm, phase 2 study of steroid-containing mouthwash for the prevention of everolimus-associated stomatitis in multiple tumor types.

Hattori M, Hagiwara S, Kotani H, Tatematsu M, Tachi M, Hijioka S, Shimizu J, Andoh M, Mizuno Y, Sawaki M, Yoshimura A, Gondo N, Adachi Y, Yoshimura K, Iwata H.

Int J Clin Oncol. 2019 Oct;24(10):1320-1327. doi: 10.1007/s10147-019-01476-0. Epub 2019 Jun 1.


Proton therapy for non-squamous cell carcinoma of the head and neck: planning comparison and toxicity.

Iwata H, Toshito T, Hayashi K, Yamada M, Omachi C, Nakajima K, Hattori Y, Hashimoto S, Kuroda Y, Okumura Y, Mizoe JE, Ogino H, Shibamoto Y.

J Radiat Res. 2019 May 31. pii: rrz036. doi: 10.1093/jrr/rrz036. [Epub ahead of print]


Neratinib after trastuzumab-based adjuvant therapy in patients from Asia with early stage HER2-positive breast cancer.

Iwata H, Masuda N, Kim SB, Inoue K, Rai Y, Fujita T, Chiu J, Ohtani S, Takahashi M, Miyaki T, Lu YS, Xu B, Yap YS, Bustam A, Yao B, Zhang B, Bryce R, Chan A.

Future Oncol. 2019 Jul;15(21):2489-2501. doi: 10.2217/fon-2019-0143. Epub 2019 May 29.


Using a Vibrotactile Biofeedback Device to Augment Foot Pressure During Walking in Healthy Older Adults: A Brief Report.

Yasuda K, Hayashi Y, Tawara A, Iwata H.

Front Psychol. 2019 May 8;10:1008. doi: 10.3389/fpsyg.2019.01008. eCollection 2019.


Neutropenia management with palbociclib in Japanese patients with advanced breast cancer.

Masuda N, Mukai H, Inoue K, Rai Y, Ohno S, Mori Y, Hashigaki S, Muramatsu Y, Umeyama Y, Iwata H, Toi M.

Breast Cancer. 2019 Sep;26(5):637-650. doi: 10.1007/s12282-019-00970-7. Epub 2019 May 24. Erratum in: Breast Cancer. 2019 Jun 5;:.


Preliminary study on the effects of movement velocity training of the upper limbs on gait ability in older adults: a nonrandomized controlled trial.

Yamamoto S, Iwata A, Yano Y, Ohmine T, Honma K, Senzaki K, Fujiwara M, Murakami T, Inoue J, Sano Y, Okagawa S, Otsuki Y, Wanaka H, Kataoka M, Iwata H.

Clin Interv Aging. 2019 May 1;14:781-788. doi: 10.2147/CIA.S202897. eCollection 2019.


Establishment of the Global SEND Alliance (G-SEND) in Japan and efficient creation of electronic SEND datasets between CROs.

Anzai T, Matsuyama T, Wasko M, Hatakeyama H, Horikawa SI, Anzai R, Iwata H, Imai N, Mizuhashi F, Tsuboi M, Okuzono T, Takagi H, Cho H, Rong BTS, Masaki F, Nakae D.

J Toxicol Pathol. 2019 Apr;32(2):119-126. doi: 10.1293/tox.2018-0066. Epub 2019 Mar 2.


Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer.

André F, Ciruelos E, Rubovszky G, Campone M, Loibl S, Rugo HS, Iwata H, Conte P, Mayer IA, Kaufman B, Yamashita T, Lu YS, Inoue K, Takahashi M, Pápai Z, Longin AS, Mills D, Wilke C, Hirawat S, Juric D; SOLAR-1 Study Group.

N Engl J Med. 2019 May 16;380(20):1929-1940. doi: 10.1056/NEJMoa1813904.


A case of giant cell tumor of the breast, clinically suspected as malignant breast tumor.

Terada M, Gondo N, Sawaki M, Hattori M, Yoshimura A, Kotani H, Adachi Y, Iwase M, Kataoka A, Sugino K, Mori M, Horisawa N, Ozaki Y, Iwata H.

Surg Case Rep. 2019 May 10;5(1):77. doi: 10.1186/s40792-019-0635-4.


Association of Parity and Infant Feeding Method with Breast Density on Mammography.

Nakajima E, Iwase T, Miyagi Y, Fujita T, Ikeda N, Ishikawa T, Iwata H.

Acad Radiol. 2019 May 6. pii: S1076-6332(19)30179-5. doi: 10.1016/j.acra.2019.03.020. [Epub ahead of print]


Effects of resveratrol treatment on mitochondria and subsequent embryonic development of bovine blastocysts cryopreserved by slow freezing.

Hayashi T, Kansaku K, Abe T, Ueda S, Iwata H.

Anim Sci J. 2019 Jul;90(7):849-856. doi: 10.1111/asj.13219. Epub 2019 May 8.


Refractory oral ulcers in eosinophilic granulomatosis with polyangiitis.

Otsuka T, Iwata H, Kosumi H, Muramatsu K, Ito T, Tsujiwaki M, Fujita Y, Kamaguchi M, Kitagawa Y, Shimizu H.

J Dermatol. 2019 Oct;46(10):e377-e378. doi: 10.1111/1346-8138.14897. Epub 2019 May 3. No abstract available.


Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats.

Nishigaki A, Kawano T, Iwata H, Aoyama B, Yamanaka D, Tateiwa H, Shigematsu-Locatelli M, Eguchi S, Locatelli FM, Yokoyama M.

J Anesth. 2019 Jun;33(3):416-425. doi: 10.1007/s00540-019-02646-0. Epub 2019 May 2.


Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive gastric cancer: a dose-expansion, phase 1 study.

Shitara K, Iwata H, Takahashi S, Tamura K, Park H, Modi S, Tsurutani J, Kadowaki S, Yamaguchi K, Iwasa S, Saito K, Fujisaki Y, Sugihara M, Shahidi J, Doi T.

Lancet Oncol. 2019 Jun;20(6):827-836. doi: 10.1016/S1470-2045(19)30088-9. Epub 2019 Apr 29. Erratum in: Lancet Oncol. 2019 May 10;:.


Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive breast cancer previously treated with trastuzumab emtansine: a dose-expansion, phase 1 study.

Tamura K, Tsurutani J, Takahashi S, Iwata H, Krop IE, Redfern C, Sagara Y, Doi T, Park H, Murthy RK, Redman RA, Jikoh T, Lee C, Sugihara M, Shahidi J, Yver A, Modi S.

Lancet Oncol. 2019 Jun;20(6):816-826. doi: 10.1016/S1470-2045(19)30097-X. Epub 2019 Apr 29. Erratum in: Lancet Oncol. 2019 May 10;:.


Effectiveness of parenting education for expectant primiparous women in Asian countries: a quantitative systematic review protocol.

Mori E, Iwata H, Maehara K, Sakajo A, Ina K, Harada N.

JBI Database System Rev Implement Rep. 2019 Jun;17(6):1034-1042. doi: 10.11124/JBISRIR-2017-003974.


Changes in the Proliferation Rate, Clonogenicity, and Radiosensitivity of Cultured Cells During and After Continuous Low-Dose-Rate Irradiation.

Wang Z, Sugie C, Nakashima M, Kondo T, Iwata H, Tsuchiya T, Shibamoto Y.

Dose Response. 2019 Apr 22;17(2):1559325819842733. doi: 10.1177/1559325819842733. eCollection 2019 Apr-Jun.

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