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Items: 1 to 50 of 69

1.

Expression and Characterization of the Human Intestinal Bacterial Enzyme Which Cleaves the C-Glycosidic Bond in 3″-Oxo-puerarin.

Nakamura K, Zhu S, Komatsu K, Hattori M, Iwashima M.

Biol Pharm Bull. 2019 Mar 1;42(3):417-423. doi: 10.1248/bpb.b18-00729. Epub 2019 Jan 10.

2.

TGF-β suppresses RasGRP1 expression and supports regulatory T cell resistance against p53-induced CD28-dependent T-cell apoptosis.

Takami M, Cunha C, Motohashi S, Nakayama T, Iwashima M.

Eur J Immunol. 2018 Dec;48(12):1938-1943. doi: 10.1002/eji.201847587. Epub 2018 Oct 24.

3.

Activated human Foxp3+ regulatory T cells produce membrane-bound TNF.

Nelson A, Cunha C, Nishimura MI, Iwashima M.

Cytokine. 2018 Nov;111:454-459. doi: 10.1016/j.cyto.2018.05.036. Epub 2018 Jun 6.

4.

Cell intrinsic characteristics of human cord blood naïve CD4T cells.

Jacks RD, Keller TJ, Nelson A, Nishimura MI, White P, Iwashima M.

Immunol Lett. 2018 Jan;193:51-57. doi: 10.1016/j.imlet.2017.11.011. Epub 2017 Nov 24.

5.

Rapid Absorption of Dry-Powder Intranasal Oxytocin.

Milewski M, Goodey A, Lee D, Rimmer E, Saklatvala R, Koyama S, Iwashima M, Haruta S.

Pharm Res. 2016 Aug;33(8):1936-44. doi: 10.1007/s11095-016-1929-x. Epub 2016 May 18.

PMID:
27194003
6.

Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability.

Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, Baker BM, Nishimura MI.

J Leukoc Biol. 2016 Sep;100(3):545-57. doi: 10.1189/jlb.2A1215-561R. Epub 2016 Feb 26.

7.

Cutting Edge: AhR Is a Molecular Target of Calcitriol in Human T Cells.

Takami M, Fujimaki K, Nishimura MI, Iwashima M.

J Immunol. 2015 Sep 15;195(6):2520-3. doi: 10.4049/jimmunol.1500344. Epub 2015 Aug 14.

8.

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.

Roediger B, Kyle R, Tay SS, Mitchell AJ, Bolton HA, Guy TV, Tan SY, Forbes-Blom E, Tong PL, Köller Y, Shklovskaya E, Iwashima M, McCoy KD, Le Gros G, Fazekas de St Groth B, Weninger W.

J Allergy Clin Immunol. 2015 Dec;136(6):1653-1663.e7. doi: 10.1016/j.jaci.2015.03.043. Epub 2015 May 27.

PMID:
26025126
9.

Pillars article: Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 1994. 263: 1136-1139.

Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A.

J Immunol. 2014 Nov 1;193(9):4279-82. No abstract available.

10.

Potential of targeting TGF-β for organ transplant patients.

Iwashima M, Love R.

Future Med Chem. 2013 Mar;5(3):281-9. doi: 10.4155/fmc.12.215. Review.

11.

Ontogeny and localization of the cells produce IL-2 in healthy animals.

Yamamoto M, Seki Y, Iwai K, Ko I, Martin A, Tsuji N, Miyagawa S, Love RB, Iwashima M.

Cytokine. 2013 Mar;61(3):831-41. doi: 10.1016/j.cyto.2012.11.026. Epub 2013 Jan 16.

12.

Enzymatic cleavage of the C-glucosidic bond of puerarin by three proteins, Mn(2+), and oxidized form of nicotinamide adenine dinucleotide.

Nakamura K, Komatsu K, Hattori M, Iwashima M.

Biol Pharm Bull. 2013;36(4):635-40. Epub 2013 Jan 17.

13.

Cellular basis of tissue regeneration by omentum.

Shah S, Lowery E, Braun RK, Martin A, Huang N, Medina M, Sethupathi P, Seki Y, Takami M, Byrne K, Wigfield C, Love RB, Iwashima M.

PLoS One. 2012;7(6):e38368. doi: 10.1371/journal.pone.0038368. Epub 2012 Jun 6.

14.

TGF-β converts apoptotic stimuli into the signal for Th9 differentiation.

Takami M, Love RB, Iwashima M.

J Immunol. 2012 May 1;188(9):4369-75. doi: 10.4049/jimmunol.1102698. Epub 2012 Mar 28.

15.

Generation of T cell hybridomas from naturally occurring FoxP3+ regulatory T cells.

Singh N, Pacholczyk R, Iwashima M, Ignatowicz L.

Methods Mol Biol. 2011;707:39-44. doi: 10.1007/978-1-61737-979-6_3.

PMID:
21287327
16.

The C-glucosyl bond of puerarin was cleaved hydrolytically by a human intestinal bacterium strain PUE to yield its aglycone daidzein and an intact glucose.

Nakamura K, Nishihata T, Jin JS, Ma CM, Komatsu K, Iwashima M, Hattori M.

Chem Pharm Bull (Tokyo). 2011;59(1):23-7.

17.

Inhibition of bleomycin-induced pulmonary fibrosis through pre-treatment with collagen type V.

Braun RK, Martin A, Shah S, Iwashima M, Medina M, Byrne K, Sethupathi P, Wigfield CH, Brand DD, Love RB.

J Heart Lung Transplant. 2010 Aug;29(8):873-80. doi: 10.1016/j.healun.2010.03.012. Epub 2010 May 14.

PMID:
20471860
18.

CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis.

Singh N, Yamamoto M, Takami M, Seki Y, Takezaki M, Mellor AL, Iwashima M.

J Immunol. 2010 Jan 1;184(1):94-104. doi: 10.4049/jimmunol.0900753. Epub 2009 Nov 30.

19.

hnRNP-K is a nuclear target of TCR-activated ERK and required for T-cell late activation.

Chang JW, Koike T, Iwashima M.

Int Immunol. 2009 Dec;21(12):1351-61. doi: 10.1093/intimm/dxp106. Epub 2009 Oct 30.

20.

Baicalein 5,6,7-trimethyl ether activates peroxisomal but not mitochondrial fatty acid beta-oxidation.

Morita M, Kanai M, Mizuno S, Iwashima M, Hayashi T, Shimozawa N, Suzuki Y, Imanaka T.

J Inherit Metab Dis. 2008 Jun;31(3):442-9. doi: 10.1007/s10545-008-0857-2. Epub 2008 May 9.

PMID:
18470630
21.

Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells.

Pacholczyk R, Kern J, Singh N, Iwashima M, Kraj P, Ignatowicz L.

Immunity. 2007 Sep;27(3):493-504.

22.

Role of CD28 in fatal autoimmune disorder in scurfy mice.

Singh N, Chandler PR, Seki Y, Baban B, Takezaki M, Kahler DJ, Munn DH, Larsen CP, Mellor AL, Iwashima M.

Blood. 2007 Aug 15;110(4):1199-206. Epub 2007 Apr 26.

23.

Enrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signaling.

Singh N, Seki Y, Takami M, Baban B, Chandler PR, Khosravi D, Zheng X, Takezaki M, Lee JR, Mellor AL, Bollag WB, Iwashima M.

Nat Methods. 2006 Aug;3(8):629-36.

PMID:
16862138
24.
25.

A synthetic study on antiviral and antioxidative chromene derivative.

Mori J, Iwashima M, Takeuchi M, Saito H.

Chem Pharm Bull (Tokyo). 2006 Mar;54(3):391-6.

26.

Solid-phase synthesis and biological activity of a combinatorial cross-conjugated dienone library.

Kitade M, Tanaka H, Oe S, Iwashima M, Iguchi K, Takahashi T.

Chemistry. 2006 Feb 1;12(5):1368-76.

PMID:
16294360
27.

Lck couples Shc to TCR signaling.

Fukushima A, Hatanaka Y, Chang JW, Takamatsu M, Singh N, Iwashima M.

Cell Signal. 2006 Aug;18(8):1182-9. Epub 2005 Oct 28.

PMID:
16257509
28.

New plastoquinones isolated from the brown alga, Sargassum micracanthum.

Mori J, Iwashima M, Wakasugi H, Saito H, Matsunaga T, Ogasawara M, Takahashi S, Suzuki H, Hayashi T.

Chem Pharm Bull (Tokyo). 2005 Sep;53(9):1159-63.

29.

Antioxidant and antiviral activities of plastoquinones from the brown alga Sargassum micracanthum, and a new chromene derivative converted from the plastoquinones.

Iwashima M, Mori J, Ting X, Matsunaga T, Hayashi K, Shinoda D, Saito H, Sankawa U, Hayashi T.

Biol Pharm Bull. 2005 Feb;28(2):374-7.

30.

Baicalein 5,6,7-trimethyl ether, a flavonoid derivative, stimulates fatty acid beta-oxidation in skin fibroblasts of X-linked adrenoleukodystrophy.

Morita M, Takahashi I, Kanai M, Okafuji F, Iwashima M, Hayashi T, Watanabe S, Hamazaki T, Shimozawa N, Suzuki Y, Furuya H, Yamada T, Imanaka T.

FEBS Lett. 2005 Jan 17;579(2):409-14.

31.

IkB-alpha-specific transcript regulation by the C-terminal end of c-Rel.

Iwai K, Lee BR, Hashiguchi M, Fukushima A, Iwashima M.

FEBS Lett. 2005 Jan 3;579(1):141-4.

32.

NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.

Ohtsuka M, Arase H, Takeuchi A, Yamasaki S, Shiina R, Suenaga T, Sakurai D, Yokosuka T, Arase N, Iwashima M, Kitamura T, Moriya H, Saito T.

Proc Natl Acad Sci U S A. 2004 May 25;101(21):8126-31. Epub 2004 May 13.

33.

Efficient solid-phase synthesis of clavulones via sequential coupling of alpha- and omega-chains.

Tanaka H, Hasegawa T, Iwashima M, Iguchi K, Takahashi T.

Org Lett. 2004 Apr 1;6(7):1103-6.

PMID:
15040733
34.

Effective irreversible alkylating reagents based on the structure of clavulones.

Tanaka H, Kitade M, Iwashima M, Iguchi K, Takahashi T.

Bioorg Med Chem Lett. 2004 Feb 23;14(4):837-40.

PMID:
15012977
35.

Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.

Mellor AL, Baban B, Chandler P, Marshall B, Jhaver K, Hansen A, Koni PA, Iwashima M, Munn DH.

J Immunol. 2003 Aug 15;171(4):1652-5.

36.
37.

A novel ERK-dependent signaling process that regulates interleukin-2 expression in a late phase of T cell activation.

Koike T, Yamagishi H, Hatanaka Y, Fukushima A, Chang JW, Xia Y, Fields M, Chandler P, Iwashima M.

J Biol Chem. 2003 May 2;278(18):15685-92. Epub 2003 Feb 20.

38.

New marine diterpenoids from the Okinawan soft coral Clavularia koellikeri.

Iwashima M, Matsumoto Y, Takenaka Y, Iguchi K, Yamori T.

J Nat Prod. 2002 Oct;65(10):1441-6.

PMID:
12398540
39.

New biologically active marine sesquiterpenoid and steroid from the okinawan sponge of the genus Axinyssa.

Iwashima M, Terada I, Iguchi K, Yamori T.

Chem Pharm Bull (Tokyo). 2002 Sep;50(9):1286-9.

40.
41.

Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.

Iwashima M, Takamatsu M, Yamagishi H, Hatanaka Y, Huang YY, McGinty C, Yamasaki S, Koike T.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4544-9. Epub 2002 Mar 26.

42.

Identification and molecular cloning of a novel brain-specific receptor protein that binds to brain injury-derived neurotrophic peptide. Possible role for neuronal survival.

Hama T, Maruyama M, Katoh-Semba R, Takizawa M, Iwashima M, Nara K.

J Biol Chem. 2001 Aug 24;276(34):31929-35. Epub 2001 Jun 8.

43.

Functional uncoupling of T-cell receptor engagement and Lck activation in anergic human thymic CD4+ T cells.

Fujimaki W, Iwashima M, Yagi J, Zhang H, Yagi H, Seo K, Imai Y, Imanishi K, Uchiyama T.

J Biol Chem. 2001 May 18;276(20):17455-60. Epub 2001 Feb 22.

44.

New marine cembrane-type diterpenoids from the Okinawan soft coral Clavularia koellikeri.

Iwashima M, Matsumoto Y, Takahashi H, Iguchi K.

J Nat Prod. 2000 Dec;63(12):1647-52.

PMID:
11141107
45.
46.

T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex.

Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C, Kamata T, Shin T, Seki N, Suzuki S, Taniguchi M, Nakayama T.

J Exp Med. 2000 Jun 5;191(11):1869-79.

47.

Impaired Ca/calcineurin pathway in in vivo anergized CD4 T cells.

Kimura M, Yamashita M, Kubo M, Iwashima M, Shimizu C, Tokoyoda K, Chiba J, Taniguchi M, Katsumata M, Nakayama T.

Int Immunol. 2000 Jun;12(6):817-24.

PMID:
10837409
48.

New marine steroids, yonarasterols, isolated from the okinawan soft coral, Clavularia viridis.

Iwashima M, Nara K, Iguchi K.

Steroids. 2000 Mar;65(3):130-7.

PMID:
10699591
49.

A new bioactive triene aldehyde from the marine sponge Leucetta microraphis.

Watanabe K, Tsuda Y, Iwashima M, Iguchi K.

J Nat Prod. 2000 Feb;63(2):258-60.

PMID:
10691722
50.

Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway.

Penna D, Müller S, Martinon F, Demotz S, Iwashima M, Valitutti S.

J Immunol. 1999 Jul 1;163(1):50-6.

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