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Items: 1 to 50 of 96

1.

A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis.

Goos JAC, Vogel WK, Mlcochova H, Millard CJ, Esfandiari E, Selman WH, Calpena E, Koelling N, Carpenter EL, Swagemakers SMA, van der Spek PJ, Filtz TM, Schwabe JWR, Iwaniec UT, Mathijssen IMJ, Leid M, Twigg SRF.

Hum Mol Genet. 2019 Apr 3. pii: ddz072. doi: 10.1093/hmg/ddz072. [Epub ahead of print]

PMID:
31067316
2.

Thermally Abused Frying Oil Potentiates Metastasis to Lung in a Murine Model of Late-Stage Breast Cancer.

Cam A, Oyirifi AB, Liu Y, Haschek WM, Iwaniec UT, Turner RT, Engeseth NJ, Helferich WG.

Cancer Prev Res (Phila). 2019 Apr;12(4):201-210. doi: 10.1158/1940-6207.CAPR-18-0220. Epub 2019 Mar 18.

PMID:
30885926
3.

Maintenance of Near Normal Bone Mass and Architecture in Lethally Irradiated Female Mice following Adoptive Transfer with as few as 750 Purified Hematopoietic Stem Cells.

Deyhle RT Jr, Wong CP, Martin SA, McDougall MQ, Olson DA, Branscum AJ, Menn SA, Iwaniec UT, Hamby DM, Turner RT.

Radiat Res. 2019 May;191(5):413-427. doi: 10.1667/RR15164.1. Epub 2019 Mar 14.

PMID:
30870097
4.

Leptin Increases Particle-Induced Osteolysis in Female ob/ob Mice.

Philbrick KA, Branscum AJ, Wong CP, Turner RT, Iwaniec UT.

Sci Rep. 2018 Oct 4;8(1):14790. doi: 10.1038/s41598-018-33173-9.

5.

Polyethylene particles inserted over calvarium induce cancellous bone loss in femur in female mice.

Philbrick KA, Wong CP, Kahler-Quesada AM, Olson DA, Branscum AJ, Turner RT, Iwaniec UT.

Bone Rep. 2018 Jul 4;9:84-92. doi: 10.1016/j.bonr.2018.07.001. eCollection 2018 Dec.

6.

Metabolic Coupling Between Bone Marrow Adipose Tissue and Hematopoiesis.

Turner RT, Martin SA, Iwaniec UT.

Curr Osteoporos Rep. 2018 Apr;16(2):95-104. doi: 10.1007/s11914-018-0422-3. Review.

7.

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice.

Miranda CL, Johnson LA, de Montgolfier O, Elias VD, Ullrich LS, Hay JJ, Paraiso IL, Choi J, Reed RL, Revel JS, Kioussi C, Bobe G, Iwaniec UT, Turner RT, Katzenellenbogen BS, Katzenellenbogen JA, Blakemore PR, Gombart AF, Maier CS, Raber J, Stevens JF.

Sci Rep. 2018 Jan 12;8(1):613. doi: 10.1038/s41598-017-18992-6.

8.

Effects of hypothalamic leptin gene therapy on osteopetrosis in leptin-deficient mice.

Philbrick KA, Martin SA, Colagiovanni AR, Branscum AJ, Turner RT, Iwaniec UT.

J Endocrinol. 2018 Feb;236(2):57-68. doi: 10.1530/JOE-17-0524. Epub 2017 Nov 30.

9.

Skeletal and Uterotrophic Effects of Endoxifen in Female Rats.

Gingery A, Iwaniec UT, Subramaniam M, Turner RT, Pitel KS, McGovern RM, Reid JM, Marler RJ, Ingle JN, Goetz MP, Hawse JR.

Endocrinology. 2017 Oct 1;158(10):3354-3368. doi: 10.1210/en.2016-1871.

10.

Low calcium diet increases 4T1 mammary tumor carcinoma cell burden and bone pathology in mice.

Wang W, Gordon JL, Philbrick KA, Yang X, Branscum AJ, Löhr CV, Haschek WM, Turner RT, Iwaniec UT, Helferich WG.

PLoS One. 2017 Jul 27;12(7):e0180886. doi: 10.1371/journal.pone.0180886. eCollection 2017.

11.

Role of estrogen receptor signaling in skeletal response to leptin in female ob/ob mice.

Turner RT, Philbrick KA, Kuah AF, Branscum AJ, Iwaniec UT.

J Endocrinol. 2017 Jun;233(3):357-367. doi: 10.1530/JOE-17-0103. Epub 2017 Apr 20.

12.

RIP140 in monocytes/macrophages regulates osteoclast differentiation and bone homeostasis.

Lee B, Iwaniec UT, Turner RT, Lin YW, Clarke BL, Gingery A, Wei LN.

JCI Insight. 2017 Apr 6;2(7):e90517. doi: 10.1172/jci.insight.90517.

13.

Bone Marrow Adipose Tissue Deficiency Increases Disuse-Induced Bone Loss in Male Mice.

Keune JA, Wong CP, Branscum AJ, Iwaniec UT, Turner RT.

Sci Rep. 2017 Apr 12;7:46325. doi: 10.1038/srep46325.

14.

High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation.

Tennant KG, Leonard SW, Wong CP, Iwaniec UT, Turner RT, Traber MG.

J Med Food. 2017 Jul;20(7):700-708. doi: 10.1089/jmf.2016.0147. Epub 2017 Apr 6.

PMID:
28384008
15.

Increasing dietary nitrate has no effect on cancellous bone loss or fecal microbiome in ovariectomized rats.

Conley MN, Roberts C, Sharpton TJ, Iwaniec UT, Hord NG.

Mol Nutr Food Res. 2017 May;61(5). doi: 10.1002/mnfr.201600372. Epub 2017 Mar 30.

16.

Leptin stimulates bone formation in ob/ob mice at doses having minimal impact on energy metabolism.

Philbrick KA, Wong CP, Branscum AJ, Turner RT, Iwaniec UT.

J Endocrinol. 2017 Mar;232(3):461-474. doi: 10.1530/JOE-16-0484. Epub 2017 Jan 5.

17.

Phosphate Binding with Sevelamer Preserves Mechanical Competence of Bone Despite Acidosis in Advanced Experimental Renal Insufficiency.

Jokihaara J, Pörsti IH, Sievänen H, Kööbi P, Kannus P, Niemelä O, Turner RT, Iwaniec UT, Järvinen TL.

PLoS One. 2016 Sep 22;11(9):e0163022. doi: 10.1371/journal.pone.0163022. eCollection 2016.

18.

Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets.

Lindenmaier LB, Philbrick KA, Branscum AJ, Kalra SP, Turner RT, Iwaniec UT.

Front Endocrinol (Lausanne). 2016 Aug 16;7:110. doi: 10.3389/fendo.2016.00110. eCollection 2016.

19.

Influence of body weight on bone mass, architecture and turnover.

Iwaniec UT, Turner RT.

J Endocrinol. 2016 Sep;230(3):R115-30. doi: 10.1530/JOE-16-0089. Epub 2016 Jun 27. Review.

20.

Dietary dried plum increases bone mass, suppresses proinflammatory cytokines and promotes attainment of peak bone mass in male mice.

Shahnazari M, Turner RT, Iwaniec UT, Wronski TJ, Li M, Ferruzzi MG, Nissenson RA, Halloran BP.

J Nutr Biochem. 2016 Aug;34:73-82. doi: 10.1016/j.jnutbio.2016.04.007. Epub 2016 May 10.

PMID:
27239754
21.

Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells.

Wang W, Belosay A, Yang X, Hartman JA, Song H, Iwaniec UT, Turner RT, Churchwell MI, Doerge DR, Helferich WG.

Clin Exp Metastasis. 2016 Jun;33(5):475-85. doi: 10.1007/s10585-016-9792-z. Epub 2016 May 21.

PMID:
27209469
22.

Room temperature housing results in premature cancellous bone loss in growing female mice: implications for the mouse as a preclinical model for age-related bone loss.

Iwaniec UT, Philbrick KA, Wong CP, Gordon JL, Kahler-Quesada AM, Olson DA, Branscum AJ, Sargent JL, DeMambro VE, Rosen CJ, Turner RT.

Osteoporos Int. 2016 Oct;27(10):3091-101. doi: 10.1007/s00198-016-3634-3. Epub 2016 May 17.

23.

Spaceflight-induced vertebral bone loss in ovariectomized rats is associated with increased bone marrow adiposity and no change in bone formation.

Keune JA, Philbrick KA, Branscum AJ, Iwaniec UT, Turner RT.

NPJ Microgravity. 2016 Apr 28;2:16016. doi: 10.1038/npjmgrav.2016.16. eCollection 2016.

24.

Alcohol: A Simple Nutrient with Complex Actions on Bone in the Adult Skeleton.

Gaddini GW, Turner RT, Grant KA, Iwaniec UT.

Alcohol Clin Exp Res. 2016 Apr;40(4):657-71. doi: 10.1111/acer.13000. Epub 2016 Mar 12. Review.

25.

Effects of Spaceflight on Bone Microarchitecture in the Axial and Appendicular Skeleton in Growing Ovariectomized Rats.

Keune JA, Branscum AJ, Iwaniec UT, Turner RT.

Sci Rep. 2015 Dec 22;5:18671. doi: 10.1038/srep18671.

26.

Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland.

Madak-Erdogan Z, Gong P, Zhao YC, Xu L, Wrobel KU, Hartman JA, Wang M, Cam A, Iwaniec UT, Turner RT, Twaddle NC, Doerge DR, Khan IA, Katzenellenbogen JA, Katzenellenbogen BS, Helferich WG.

Mol Nutr Food Res. 2016 Feb;60(2):369-80. doi: 10.1002/mnfr.201500445. Epub 2015 Nov 10.

27.

Hypothalamic leptin gene therapy reduces body weight without accelerating age-related bone loss.

Turner RT, Dube M, Branscum AJ, Wong CP, Olson DA, Zhong X, Kweh MF, Larkin IV, Wronski TJ, Rosen CJ, Kalra SP, Iwaniec UT.

J Endocrinol. 2015 Dec;227(3):129-41. doi: 10.1530/JOE-15-0280. Epub 2015 Oct 20.

28.

BCL11B regulates sutural patency in the mouse craniofacial skeleton.

Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M.

Dev Biol. 2016 Jul 15;415(2):251-260. doi: 10.1016/j.ydbio.2015.10.010. Epub 2015 Oct 9.

29.

Paradoxical effects of partial leptin deficiency on bone in growing female mice.

Philbrick KA, Turner RT, Branscum AJ, Wong CP, Iwaniec UT.

Anat Rec (Hoboken). 2015 Dec;298(12):2018-29. doi: 10.1002/ar.23267. Epub 2015 Oct 7.

30.

Twelve months of voluntary heavy alcohol consumption in male rhesus macaques suppresses intracortical bone remodeling.

Gaddini GW, Grant KA, Woodall A, Stull C, Maddalozzo GF, Zhang B, Turner RT, Iwaniec UT.

Bone. 2015 Feb;71:227-36. doi: 10.1016/j.bone.2014.10.025. Epub 2014 Nov 7.

31.

Morbid obesity attenuates the skeletal abnormalities associated with leptin deficiency in mice.

Turner RT, Philbrick KA, Wong CP, Olson DA, Branscum AJ, Iwaniec UT.

J Endocrinol. 2014 Oct;223(1):M1-15. doi: 10.1530/JOE-14-0224. Epub 2014 Jul 2.

32.

The effects of a novel hormonal breast cancer therapy, endoxifen, on the mouse skeleton.

Gingery A, Subramaniam M, Pitel KS, Reese JM, Cicek M, Lindenmaier LB, Ingle JN, Goetz MP, Turner RT, Iwaniec UT, Spelsberg TC, Hawse JR.

PLoS One. 2014 May 22;9(5):e98219. doi: 10.1371/journal.pone.0098219. eCollection 2014.

33.

Effects of treadmill training on combined goserelin acetate and doxorubicin-induced osteopenia in female rats.

Hydock DS, Parry TL, Wymore JD, Iwaniec UT, Turner RT, Schneider CM, Hayward R.

J Musculoskelet Neuronal Interact. 2014 Mar;14(1):10-8.

34.

Effects of chronic heavy alcohol consumption and endurance exercise on cancellous and cortical bone microarchitecture in adult male rats.

Johnson TL, Gaddini G, Branscum AJ, Olson DA, Caroline-Westerlind K, Turner RT, Iwaniec UT.

Alcohol Clin Exp Res. 2014 May;38(5):1365-72. doi: 10.1111/acer.12366. Epub 2014 Feb 11.

35.

TGFβ inducible early gene-1 plays an important role in mediating estrogen signaling in the skeleton.

Hawse JR, Pitel KS, Cicek M, Philbrick KA, Gingery A, Peters KD, Syed FA, Ingle JN, Suman VJ, Iwaniec UT, Turner RT, Spelsberg TC, Subramaniam M.

J Bone Miner Res. 2014;29(5):1206-16. doi: 10.1002/jbmr.2142.

36.

Estradiol increases ER-negative breast cancer metastasis in an experimental model.

Yang X, Belosay A, Du M, Fan TM, Turner RT, Iwaniec UT, Helferich WG.

Clin Exp Metastasis. 2013 Aug;30(6):711-21. doi: 10.1007/s10585-012-9559-0. Epub 2013 Oct 5.

37.

Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents.

Iwaniec UT, Turner RT, Smith BJ, Stoecker BJ, Rust A, Zhang B, Vasu VT, Gohil K, Cross CE, Traber MG.

Free Radic Biol Med. 2013 Dec;65:1209-1214. doi: 10.1016/j.freeradbiomed.2013.09.004. Epub 2013 Sep 16.

38.

Acute exposure to high dose γ-radiation results in transient activation of bone lining cells.

Turner RT, Iwaniec UT, Wong CP, Lindenmaier LB, Wagner LA, Branscum AJ, Menn SA, Taylor J, Zhang Y, Wu H, Sibonga JD.

Bone. 2013 Nov;57(1):164-73. doi: 10.1016/j.bone.2013.08.002. Epub 2013 Aug 14.

39.

Intraperitoneal injection of ethanol results in drastic changes in bone metabolism not observed when ethanol is administered by oral gavage.

Iwaniec UT, Turner RT.

Alcohol Clin Exp Res. 2013 Aug;37(8):1271-7. doi: 10.1111/acer.12105. Epub 2013 Mar 29.

40.

Genistein administered as a once-daily oral supplement had no beneficial effect on the tibia in rat models for postmenopausal bone loss.

Turner RT, Iwaniec UT, Andrade JE, Branscum AJ, Neese SL, Olson DA, Wagner L, Wang VC, Schantz SL, Helferich WG.

Menopause. 2013 Jun;20(6):677-86. doi: 10.1097/gme.0b013e31827d44df.

41.

Failure to generate bone marrow adipocytes does not protect mice from ovariectomy-induced osteopenia.

Iwaniec UT, Turner RT.

Bone. 2013 Mar;53(1):145-53. doi: 10.1016/j.bone.2012.11.034. Epub 2012 Dec 12.

42.

Voluntary wheel running in growing rats does not protect against doxorubicin-induced osteopenia.

Hayward R, Iwaniec UT, Turner RT, Lien CY, Jensen BT, Hydock DS, Schneider CM.

J Pediatr Hematol Oncol. 2013 May;35(4):e144-8. doi: 10.1097/MPH.0b013e318279b1fb.

PMID:
23211689
43.

Moderate alcohol intake lowers biochemical markers of bone turnover in postmenopausal women.

Marrone JA, Maddalozzo GF, Branscum AJ, Hardin K, Cialdella-Kam L, Philbrick KA, Breggia AC, Rosen CJ, Turner RT, Iwaniec UT.

Menopause. 2012 Sep;19(9):974-9. doi: 10.1097/gme.0b013e31824ac071.

44.

Androgen prevents hypogonadal bone loss via inhibition of resorption mediated by mature osteoblasts/osteocytes.

Wiren KM, Zhang XW, Olson DA, Turner RT, Iwaniec UT.

Bone. 2012 Nov;51(5):835-46. doi: 10.1016/j.bone.2012.08.111. Epub 2012 Aug 14.

45.

Peripheral leptin regulates bone formation.

Turner RT, Kalra SP, Wong CP, Philbrick KA, Lindenmaier LB, Boghossian S, Iwaniec UT.

J Bone Miner Res. 2013 Jan;28(1):22-34. doi: 10.1002/jbmr.1734.

46.

Bone and hypopituitarism: not only a mass issue.

Iwaniec UT.

Endocrine. 2012 Oct;42(2):234-6. No abstract available.

47.

MicroRNAs control neurobehavioral development and function in zebrafish.

Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL.

FASEB J. 2012 Apr;26(4):1452-61. doi: 10.1096/fj.11-194464. Epub 2012 Jan 17.

48.

Effects of increased hypothalamic leptin gene expression on ovariectomy-induced bone loss in rats.

Jackson MA, Iwaniec UT, Turner RT, Wronski TJ, Kalra SP.

Peptides. 2011 Aug;32(8):1575-80. doi: 10.1016/j.peptides.2011.04.029. Epub 2011 May 27.

49.

Effect of reduced c-Kit signaling on bone marrow adiposity.

Turner RT, Wong CP, Iwaniec UT.

Anat Rec (Hoboken). 2011 Jul;294(7):1126-34. doi: 10.1002/ar.21409. Epub 2011 Jun 1.

50.

Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats.

Iwaniec UT, Boghossian S, Trevisiol CH, Wronski TJ, Turner RT, Kalra SP.

J Bone Miner Res. 2011 Jul;26(7):1506-16. doi: 10.1002/jbmr.365.

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