Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 717

1.

Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.

Sakurai K, Dainichi T, Garcet S, Tsuchiya S, Yamamoto Y, Kitoh A, Honda T, Nomura T, Egawa G, Otsuka A, Nakajima S, Matsumoto R, Nakano Y, Otsuka M, Iwakura Y, Grinberg-Bleyer Y, Ghosh S, Sugimoto Y, Guttman-Yassky E, Krueger JG, Kabashima K.

J Allergy Clin Immunol. 2019 Jul 18. pii: S0091-6749(19)30832-2. doi: 10.1016/j.jaci.2019.06.019. [Epub ahead of print]

PMID:
31378305
2.

Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases.

Kobayashi Y, Iwakura Y, Sotoyama H, Kitayama E, Takei N, Someya T, Nawa H.

Transl Psychiatry. 2019 Aug 1;9(1):181. doi: 10.1038/s41398-019-0519-1.

3.

USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells.

Piatnitskaia S, Takahashi M, Kitaura H, Katsuragi Y, Kakihana T, Zhang L, Kakita A, Iwakura Y, Nawa H, Miura T, Ikeuchi T, Hara T, Fujii M.

Sci Rep. 2019 Jul 22;9(1):10591. doi: 10.1038/s41598-019-47033-7.

4.

AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.

Hupa KJ, Stein K, Schneider R, Lysson M, Schneiker B, Hornung V, Latz E, Iwakura Y, Kalff JC, Wehner S.

Sci Rep. 2019 Jul 22;9(1):10602. doi: 10.1038/s41598-019-46968-1.

5.

CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis.

Blanco-Pérez F, Kato Y, Gonzalez-Menendez I, Laiño J, Ohbayashi M, Burggraf M, Krause M, Kirberg J, Iwakura Y, Martella M, Quintanilla-Martinez L, Shibata N, Vieths S, Scheurer S, Toda M.

Sci Rep. 2019 Jul 3;9(1):9608. doi: 10.1038/s41598-019-45653-7.

6.

Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis.

Miyabe C, Miyabe Y, Bricio-Moreno L, Lian J, Rahimi RA, Miura NN, Ohno N, Iwakura Y, Kawakami T, Luster AD.

J Clin Invest. 2019 Jun 6;130:3610-3624. doi: 10.1172/JCI123778.

7.

Large Scale Calcium Imaging of the Cerebellar Vermis During Sensory Stimulus Unravels Two Response's Components That Differ in Their Spatiotemporal Properties.

Byk H, Huang GJ, Iwakura Y, Yarom Y.

Front Syst Neurosci. 2019 May 8;13:18. doi: 10.3389/fnsys.2019.00018. eCollection 2019.

8.

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.

Drummond RA, Swamydas M, Oikonomou V, Zhai B, Dambuza IM, Schaefer BC, Bohrer AC, Mayer-Barber KD, Lira SA, Iwakura Y, Filler SG, Brown GD, Hube B, Naglik JR, Hohl TM, Lionakis MS.

Nat Immunol. 2019 May;20(5):559-570. doi: 10.1038/s41590-019-0377-2. Epub 2019 Apr 17.

PMID:
30996332
9.

Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role.

Lau L, Porciuncula A, Yu A, Iwakura Y, David G.

Mol Cell Biol. 2019 May 28;39(12). pii: e00586-18. doi: 10.1128/MCB.00586-18. Print 2019 Jun 15.

PMID:
30988157
10.

Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors.

Tang C, Makusheva Y, Sun H, Han W, Iwakura Y.

J Leukoc Biol. 2019 Apr 9. doi: 10.1002/JLB.2RI0119-031R. [Epub ahead of print] Review.

PMID:
30964564
11.

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.

Schwartz C, Moran T, Saunders SP, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, O'Neill L, Irvine AD, McKenzie ANJ, Ogg G, Walsh PT, Demengeot J, Fallon PG.

Allergy. 2019 Apr 2. doi: 10.1111/all.13801. [Epub ahead of print]

PMID:
30937919
12.

IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice.

Matsushita N, Ishida N, Ibi M, Saito M, Takahashi M, Taniguchi S, Iwakura Y, Morino Y, Taira E, Sawa Y, Hirose M.

Biol Pharm Bull. 2019;42(4):543-546. doi: 10.1248/bpb.b18-00363.

13.

Epidermal loss of phospholipase Cδ1 attenuates irritant contact dermatitis.

Shiratori K, Kanemaru K, Ogura T, Nakajima A, Sugizaki Y, Fukuyama T, Iwakura Y, Nakamura Y, Fukami K.

Biochem Biophys Res Commun. 2019 Apr 2;511(2):330-335. doi: 10.1016/j.bbrc.2019.02.046. Epub 2019 Feb 18.

PMID:
30791982
14.

Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration.

Fan Q, Tao R, Zhang H, Xie H, Lu L, Wang T, Su M, Hu J, Zhang Q, Chen Q, Iwakura Y, Shen W, Zhang R, Yan X.

Circulation. 2019 Jan 29;139(5):663-678. doi: 10.1161/CIRCULATIONAHA.118.036044.

PMID:
30586706
15.

Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia.

Yukawa T, Iwakura Y, Takei N, Saito M, Watanabe Y, Toyooka K, Igarashi M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Iritani S, Niwa SI, Takeuchi R, Takahashi H, Kakita A, Someya T, Nawa H.

Psychiatry Res. 2018 Dec;270:940-946. doi: 10.1016/j.psychres.2018.10.062. Epub 2018 Oct 30.

PMID:
30551347
16.

USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.

Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.

iScience. 2018 Nov 30;9:433-450. doi: 10.1016/j.isci.2018.11.006. Epub 2018 Nov 5.

17.

Dectin-2-Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation.

Miura T, Kawakami K, Kanno E, Tanno H, Tada H, Sato N, Masaki A, Yokoyama R, Kawamura K, Kitai Y, Takagi N, Yamaguchi K, Yamaguchi N, Kyo Y, Ishii K, Imai Y, Saijo S, Iwakura Y, Tachi M.

J Invest Dermatol. 2019 Mar;139(3):702-711. doi: 10.1016/j.jid.2018.10.015. Epub 2018 Oct 28.

PMID:
30393083
18.

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.

Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, Fisher A, Kaiser WJ, Murayama MA, Iwakura Y, Gao J, Carman J, Dongre A, Dubyak G, Abbott DW, Shi FD, Ransohoff RM, Li X.

J Clin Invest. 2018 Dec 3;128(12):5399-5412. doi: 10.1172/JCI121901. Epub 2018 Oct 29.

19.

IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse.

Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, Nakamura S, Kaneko Y, Kobayashi S, Harato K, Yoshimura A, Iwakura Y, Takeuchi T, Matsumoto M, Nakamura M, Niki Y, Miyamoto T.

Sci Rep. 2018 Oct 25;8(1):15783. doi: 10.1038/s41598-018-34173-5.

20.

IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity.

Numata T, Yoshizaki T, Yamaguchi S, Shimura E, Iwakura Y, Harada K, Sudo K, Tsuboi R, Nakae S.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):429-436. doi: 10.1016/j.bbrc.2018.10.104. Epub 2018 Oct 22.

PMID:
30352688
21.

A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis.

Ueno K, Urai M, Sadamoto S, Shinozaki M, Takatsuka S, Abe M, Otani Y, Yanagihara N, Shimizu K, Iwakura Y, Shibuya K, Miyazaki Y, Kinjo Y.

Mucosal Immunol. 2019 Jan;12(1):265-276. doi: 10.1038/s41385-018-0094-4. Epub 2018 Oct 2.

PMID:
30279512
22.

The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.

Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura M, Akira S, Tominaga M.

iScience. 2018 Aug 31;6:306-318. doi: 10.1016/j.isci.2018.08.007. Epub 2018 Aug 15.

23.

High prevalence of shoplifting in patients with eating disorders.

Miyawaki D, Goto A, Harada T, Yamauchi T, Iwakura Y, Terakawa H, Hirai K, Miki Y, Harima Y, Inoue K.

Eat Weight Disord. 2018 Dec;23(6):761-768. doi: 10.1007/s40519-018-0575-1. Epub 2018 Sep 16.

PMID:
30221324
24.

MAIT cells protect against pulmonary Legionella longbeachae infection.

Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z.

Nat Commun. 2018 Aug 22;9(1):3350. doi: 10.1038/s41467-018-05202-8.

25.

Interleukin-17-producing γδ T (γδ17) cells in inflammatory diseases.

Akitsu A, Iwakura Y.

Immunology. 2018 Dec;155(4):418-426. doi: 10.1111/imm.12993. Epub 2018 Sep 10. Review.

26.

Role of interleukin-17 in a murine community-associated methicillin-resistant Staphylococcus aureus pneumonia model.

Shibue Y, Kimura S, Kajiwara C, Iwakura Y, Yamaguchi K, Tateda K.

Microbes Infect. 2019 Jan - Feb;21(1):33-39. doi: 10.1016/j.micinf.2018.06.006. Epub 2018 Jul 17.

PMID:
30026066
27.

Preschool-onset obsessive-compulsive disorder with complete remission.

Miyawaki D, Goto A, Iwakura Y, Hirai K, Miki Y, Asada N, Terakawa H, Inoue K.

Neuropsychiatr Dis Treat. 2018 Jul 3;14:1747-1753. doi: 10.2147/NDT.S169797. eCollection 2018.

28.

BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance.

Matsushita T, Kobayashi T, Mizumaki K, Kano M, Sawada T, Tennichi M, Okamura A, Hamaguchi Y, Iwakura Y, Hasegawa M, Fujimoto M, Takehara K.

Sci Adv. 2018 Jul 11;4(7):eaas9944. doi: 10.1126/sciadv.aas9944. eCollection 2018 Jul.

29.

Investigation into the plasma concentration of ω3 polyunsaturated fatty acids in Japanese attention-deficit hyperactivity disorder patients.

Yonezawa K, Nonaka S, Iwakura Y, Kusano Y, Funamoto Y, Kanchi N, Yamaguchi N, Kusumoto Y, Imamura A, Ozawa H.

J Neural Transm (Vienna). 2018 Sep;125(9):1395-1400. doi: 10.1007/s00702-018-1895-z. Epub 2018 Jun 20.

PMID:
29926268
30.

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota.

Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y.

Nat Immunol. 2018 Jul;19(7):755-765. doi: 10.1038/s41590-018-0134-y. Epub 2018 Jun 18.

PMID:
29915298
31.

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation.

Isoda K, Akita K, Kitamura K, Sato-Okabayashi Y, Kadoguchi T, Isobe S, Ohtomo F, Sano M, Shimada K, Iwakura Y, Daida H.

Int J Cardiol. 2018 Nov 1;270:221-227. doi: 10.1016/j.ijcard.2018.05.072. Epub 2018 Jun 6.

PMID:
29884291
32.

IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop.

Hashiguchi Y, Yabe R, Chung SH, Murayama MA, Yoshida K, Matsuo K, Kubo S, Saijo S, Nakamura Y, Matsue H, Iwakura Y.

J Immunol. 2018 Jul 1;201(1):167-182. doi: 10.4049/jimmunol.1701157. Epub 2018 May 23.

33.

A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis.

Jeschke JC, Mayne CG, Ziegelbauer J, DeCiantis CL, Singh S, Kumar SN, Suchi M, Iwakura Y, Drobyski WR, Salzman NH, Williams CB.

Mucosal Immunol. 2018 Jul;11(4):1127-1137. doi: 10.1038/s41385-018-0023-6. Epub 2018 May 4.

34.

Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.

Tong H, Miyake Y, Mi-Ichi F, Iwakura Y, Hara H, Yoshida H.

PLoS One. 2018 Mar 29;13(3):e0195119. doi: 10.1371/journal.pone.0195119. eCollection 2018.

35.

IL-25 enhances TH17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells.

Suto H, Nambu A, Morita H, Yamaguchi S, Numata T, Yoshizaki T, Shimura E, Arae K, Asada Y, Motomura K, Kaneko M, Abe T, Matsuda A, Iwakura Y, Okumura K, Saito H, Matsumoto K, Sudo K, Nakae S.

J Allergy Clin Immunol. 2018 Nov;142(5):1500-1509.e10. doi: 10.1016/j.jaci.2017.12.1007. Epub 2018 Mar 6.

PMID:
29522843
36.

Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α-deficient B cells.

Zhu G, Liu X, Fang Y, Zhai B, Xu R, Han G, Chen G, Xiao H, Hou C, Shen B, Li Y, Iwakura Y, Wang L, Jiang Z, Ma N, Liu G, Wang R.

Cell Immunol. 2018 Jun;328:9-17. doi: 10.1016/j.cellimm.2018.02.015. Epub 2018 Feb 24.

PMID:
29499909
37.

Host defense against oral microbiota by bone-damaging T cells.

Tsukasaki M, Komatsu N, Nagashima K, Nitta T, Pluemsakunthai W, Shukunami C, Iwakura Y, Nakashima T, Okamoto K, Takayanagi H.

Nat Commun. 2018 Feb 16;9(1):701. doi: 10.1038/s41467-018-03147-6.

38.

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.

Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.

Nat Commun. 2018 Feb 14;9(1):672. doi: 10.1038/s41467-018-03051-z.

39.

Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.

Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S, Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.

Sci Rep. 2018 Jan 31;8(1):2021. doi: 10.1038/s41598-018-19769-1.

40.

HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance.

Liu S, Lee JS, Jie C, Park MH, Iwakura Y, Patel Y, Soni M, Reisman D, Chen H.

Cancer Res. 2018 Apr 15;78(8):2040-2051. doi: 10.1158/0008-5472.CAN-17-2761. Epub 2018 Jan 30.

41.

IL-1R2 deficiency suppresses dextran sodium sulfate-induced colitis in mice via regulation of microbiota.

Yoshida K, Murayama MA, Shimizu K, Tang C, Katagiri N, Matsuo K, Fukai F, Iwakura Y.

Biochem Biophys Res Commun. 2018 Feb 12;496(3):934-940. doi: 10.1016/j.bbrc.2018.01.116. Epub 2018 Feb 2.

PMID:
29366788
42.

NK Cells Control Tumor-Promoting Function of Neutrophils in Mice.

Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y.

Cancer Immunol Res. 2018 Mar;6(3):348-357. doi: 10.1158/2326-6066.CIR-17-0204. Epub 2018 Jan 23.

43.

Brain Interleukin-1 Facilitates Learning of a Water Maze Spatial Memory Task in Young Mice.

Takemiya T, Fumizawa K, Yamagata K, Iwakura Y, Kawakami M.

Front Behav Neurosci. 2017 Oct 23;11:202. doi: 10.3389/fnbeh.2017.00202. eCollection 2017.

44.

LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae.

Lamprinaki D, Beasy G, Zhekova A, Wittmann A, James S, Dicks J, Iwakura Y, Saijo S, Wang X, Chow CW, Roberts I, Korcsmaros T, Mayer U, Wileman T, Kawasaki N.

Front Immunol. 2017 Oct 25;8:1397. doi: 10.3389/fimmu.2017.01397. eCollection 2017.

45.

β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.

Kamiya T, Tang C, Kadoki M, Oshima K, Hattori M, Saijo S, Adachi Y, Ohno N, Iwakura Y.

Mucosal Immunol. 2018 May;11(3):763-773. doi: 10.1038/mi.2017.86. Epub 2017 Oct 25.

PMID:
29068000
46.

Production of low-molecular weight soluble yeast β-glucan by an acid degradation method.

Ishimoto Y, Ishibashi KI, Yamanaka D, Adachi Y, Kanzaki K, Iwakura Y, Ohno N.

Int J Biol Macromol. 2018 Feb;107(Pt B):2269-2278. doi: 10.1016/j.ijbiomac.2017.10.094. Epub 2017 Oct 16.

PMID:
29051097
47.

Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice.

Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, Mauny P, Lory R, Uttenhove C, van Snick J, Iwakura Y, di Padova F, Quesniaux V, Togbe D, Ryffel B.

Clin Sci (Lond). 2017 Oct 12;131(20):2533-2548. doi: 10.1042/CS20171034. Print 2017 Oct 15.

PMID:
29026003
48.

Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S.

Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241c.

PMID:
28985207
49.

IL-17A contributes to reducing IFN-γ/IL-4 ratio and persistence of Entamoeba histolytica during intestinal amebiasis.

Deloer S, Nakamura R, Kikuchi M, Moriyasu T, Kalenda YDJ, Mohammed ES, Senba M, Iwakura Y, Yoshida H, Hamano S.

Parasitol Int. 2017 Dec;66(6):817-823. doi: 10.1016/j.parint.2017.09.011. Epub 2017 Sep 18.

PMID:
28927906
50.

Interleukin-17A-Deficient Mice Are Highly Susceptible to Toxoplasma gondii Infection Due to Excessively Induced T. gondii HSP70 and Interferon Gamma Production.

Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F.

Infect Immun. 2017 Nov 17;85(12). pii: e00399-17. doi: 10.1128/IAI.00399-17. Print 2017 Dec.

Supplemental Content

Loading ...
Support Center