Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 701

1.

USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.

Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.

iScience. 2018 Nov 30;9:433-450. doi: 10.1016/j.isci.2018.11.006. Epub 2018 Nov 5.

2.

Dectin-2-mediated signaling leads to delayed skin wound healing through enhanced neutrophilic inflammatory response and neutrophil extracellular traps formation.

Miura T, Kawakami K, Kanno E, Tanno H, Tada H, Sato N, Masaki A, Yokoyama R, Kawamura K, Kitai Y, Takagi N, Yamaguchi K, Yamaguchi N, Kyo Y, Ishii K, Imai Y, Saijo S, Iwakura Y, Tachi M.

J Invest Dermatol. 2018 Oct 27. pii: S0022-202X(18)32706-4. doi: 10.1016/j.jid.2018.10.015. [Epub ahead of print]

PMID:
30393083
3.

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.

Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, Fisher A, Kaiser WJ, Murayama MA, Iwakura Y, Gao J, Carman J, Dongre A, Dubyak G, Abbott DW, Shi FD, Ransohoff RM, Li X.

J Clin Invest. 2018 Oct 29. pii: 121901. doi: 10.1172/JCI121901. [Epub ahead of print]

4.

IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse.

Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, Nakamura S, Kaneko Y, Kobayashi S, Harato K, Yoshimura A, Iwakura Y, Takeuchi T, Matsumoto M, Nakamura M, Niki Y, Miyamoto T.

Sci Rep. 2018 Oct 25;8(1):15783. doi: 10.1038/s41598-018-34173-5.

5.

IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity.

Numata T, Yoshizaki T, Yamaguchi S, Shimura E, Iwakura Y, Harada K, Sudo K, Tsuboi R, Nakae S.

Biochem Biophys Res Commun. 2018 Nov 30;506(3):429-436. doi: 10.1016/j.bbrc.2018.10.104. Epub 2018 Oct 22.

PMID:
30352688
6.

A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis.

Ueno K, Urai M, Sadamoto S, Shinozaki M, Takatsuka S, Abe M, Otani Y, Yanagihara N, Shimizu K, Iwakura Y, Shibuya K, Miyazaki Y, Kinjo Y.

Mucosal Immunol. 2018 Oct 2. doi: 10.1038/s41385-018-0094-4. [Epub ahead of print]

PMID:
30279512
7.

The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.

Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura M, Akira S, Tominaga M.

iScience. 2018 Aug 31;6:306-318. doi: 10.1016/j.isci.2018.08.007. Epub 2018 Aug 15.

8.

High prevalence of shoplifting in patients with eating disorders.

Miyawaki D, Goto A, Harada T, Yamauchi T, Iwakura Y, Terakawa H, Hirai K, Miki Y, Harima Y, Inoue K.

Eat Weight Disord. 2018 Sep 16. doi: 10.1007/s40519-018-0575-1. [Epub ahead of print]

PMID:
30221324
9.

MAIT cells protect against pulmonary Legionella longbeachae infection.

Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z.

Nat Commun. 2018 Aug 22;9(1):3350. doi: 10.1038/s41467-018-05202-8.

10.

Interleukin-17-producing γδ T (γδ17) cells in inflammatory diseases.

Akitsu A, Iwakura Y.

Immunology. 2018 Dec;155(4):418-426. doi: 10.1111/imm.12993. Epub 2018 Sep 10. Review.

11.

Role of interleukin-17 in a murine community-associated methicillin-resistant Staphylococcus aureus pneumonia model.

Shibue Y, Kimura S, Kajiwara C, Iwakura Y, Yamaguchi K, Tateda K.

Microbes Infect. 2018 Jul 17. pii: S1286-4579(18)30145-X. doi: 10.1016/j.micinf.2018.06.006. [Epub ahead of print]

PMID:
30026066
12.

Preschool-onset obsessive-compulsive disorder with complete remission.

Miyawaki D, Goto A, Iwakura Y, Hirai K, Miki Y, Asada N, Terakawa H, Inoue K.

Neuropsychiatr Dis Treat. 2018 Jul 3;14:1747-1753. doi: 10.2147/NDT.S169797. eCollection 2018.

13.

BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance.

Matsushita T, Kobayashi T, Mizumaki K, Kano M, Sawada T, Tennichi M, Okamura A, Hamaguchi Y, Iwakura Y, Hasegawa M, Fujimoto M, Takehara K.

Sci Adv. 2018 Jul 11;4(7):eaas9944. doi: 10.1126/sciadv.aas9944. eCollection 2018 Jul.

14.

Investigation into the plasma concentration of ω3 polyunsaturated fatty acids in Japanese attention-deficit hyperactivity disorder patients.

Yonezawa K, Nonaka S, Iwakura Y, Kusano Y, Funamoto Y, Kanchi N, Yamaguchi N, Kusumoto Y, Imamura A, Ozawa H.

J Neural Transm (Vienna). 2018 Jun 20. doi: 10.1007/s00702-018-1895-z. [Epub ahead of print]

PMID:
29926268
15.

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota.

Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y.

Nat Immunol. 2018 Jul;19(7):755-765. doi: 10.1038/s41590-018-0134-y. Epub 2018 Jun 18.

PMID:
29915298
16.

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation.

Isoda K, Akita K, Kitamura K, Sato-Okabayashi Y, Kadoguchi T, Isobe S, Ohtomo F, Sano M, Shimada K, Iwakura Y, Daida H.

Int J Cardiol. 2018 Nov 1;270:221-227. doi: 10.1016/j.ijcard.2018.05.072. Epub 2018 Jun 6.

PMID:
29884291
17.

IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop.

Hashiguchi Y, Yabe R, Chung SH, Murayama MA, Yoshida K, Matsuo K, Kubo S, Saijo S, Nakamura Y, Matsue H, Iwakura Y.

J Immunol. 2018 Jul 1;201(1):167-182. doi: 10.4049/jimmunol.1701157. Epub 2018 May 23.

PMID:
29794016
18.

A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis.

Jeschke JC, Mayne CG, Ziegelbauer J, DeCiantis CL, Singh S, Kumar SN, Suchi M, Iwakura Y, Drobyski WR, Salzman NH, Williams CB.

Mucosal Immunol. 2018 Jul;11(4):1127-1137. doi: 10.1038/s41385-018-0023-6. Epub 2018 May 4.

PMID:
29728642
19.

Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.

Tong H, Miyake Y, Mi-Ichi F, Iwakura Y, Hara H, Yoshida H.

PLoS One. 2018 Mar 29;13(3):e0195119. doi: 10.1371/journal.pone.0195119. eCollection 2018.

20.

IL-25 enhances TH17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells.

Suto H, Nambu A, Morita H, Yamaguchi S, Numata T, Yoshizaki T, Shimura E, Arae K, Asada Y, Motomura K, Kaneko M, Abe T, Matsuda A, Iwakura Y, Okumura K, Saito H, Matsumoto K, Sudo K, Nakae S.

J Allergy Clin Immunol. 2018 Nov;142(5):1500-1509.e10. doi: 10.1016/j.jaci.2017.12.1007. Epub 2018 Mar 6.

PMID:
29522843
21.

Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α-deficient B cells.

Zhu G, Liu X, Fang Y, Zhai B, Xu R, Han G, Chen G, Xiao H, Hou C, Shen B, Li Y, Iwakura Y, Wang L, Jiang Z, Ma N, Liu G, Wang R.

Cell Immunol. 2018 Jun;328:9-17. doi: 10.1016/j.cellimm.2018.02.015. Epub 2018 Feb 24.

PMID:
29499909
22.

Host defense against oral microbiota by bone-damaging T cells.

Tsukasaki M, Komatsu N, Nagashima K, Nitta T, Pluemsakunthai W, Shukunami C, Iwakura Y, Nakashima T, Okamoto K, Takayanagi H.

Nat Commun. 2018 Feb 16;9(1):701. doi: 10.1038/s41467-018-03147-6.

23.

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.

Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.

Nat Commun. 2018 Feb 14;9(1):672. doi: 10.1038/s41467-018-03051-z.

24.

Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.

Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S, Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.

Sci Rep. 2018 Jan 31;8(1):2021. doi: 10.1038/s41598-018-19769-1.

25.

HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance.

Liu S, Lee JS, Jie C, Park MH, Iwakura Y, Patel Y, Soni M, Reisman D, Chen H.

Cancer Res. 2018 Apr 15;78(8):2040-2051. doi: 10.1158/0008-5472.CAN-17-2761. Epub 2018 Jan 30.

PMID:
29382706
26.

IL-1R2 deficiency suppresses dextran sodium sulfate-induced colitis in mice via regulation of microbiota.

Yoshida K, Murayama MA, Shimizu K, Tang C, Katagiri N, Matsuo K, Fukai F, Iwakura Y.

Biochem Biophys Res Commun. 2018 Feb 12;496(3):934-940. doi: 10.1016/j.bbrc.2018.01.116. Epub 2018 Feb 2.

PMID:
29366788
27.

NK Cells Control Tumor-Promoting Function of Neutrophils in Mice.

Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y.

Cancer Immunol Res. 2018 Jan 23. doi: 10.1158/2326-6066.CIR-17-0204. [Epub ahead of print]

PMID:
29362222
28.

Brain Interleukin-1 Facilitates Learning of a Water Maze Spatial Memory Task in Young Mice.

Takemiya T, Fumizawa K, Yamagata K, Iwakura Y, Kawakami M.

Front Behav Neurosci. 2017 Oct 23;11:202. doi: 10.3389/fnbeh.2017.00202. eCollection 2017.

29.

LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae.

Lamprinaki D, Beasy G, Zhekova A, Wittmann A, James S, Dicks J, Iwakura Y, Saijo S, Wang X, Chow CW, Roberts I, Korcsmaros T, Mayer U, Wileman T, Kawasaki N.

Front Immunol. 2017 Oct 25;8:1397. doi: 10.3389/fimmu.2017.01397. eCollection 2017.

30.

β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.

Kamiya T, Tang C, Kadoki M, Oshima K, Hattori M, Saijo S, Adachi Y, Ohno N, Iwakura Y.

Mucosal Immunol. 2018 May;11(3):763-773. doi: 10.1038/mi.2017.86. Epub 2017 Oct 25.

PMID:
29068000
31.

Production of low-molecular weight soluble yeast β-glucan by an acid degradation method.

Ishimoto Y, Ishibashi KI, Yamanaka D, Adachi Y, Kanzaki K, Iwakura Y, Ohno N.

Int J Biol Macromol. 2018 Feb;107(Pt B):2269-2278. doi: 10.1016/j.ijbiomac.2017.10.094. Epub 2017 Oct 16.

PMID:
29051097
32.

Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice.

Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, Mauny P, Lory R, Uttenhove C, van Snick J, Iwakura Y, di Padova F, Quesniaux V, Togbe D, Ryffel B.

Clin Sci (Lond). 2017 Oct 12;131(20):2533-2548. doi: 10.1042/CS20171034. Print 2017 Oct 15.

PMID:
29026003
33.

Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S.

Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241c.

PMID:
28985207
34.

IL-17A contributes to reducing IFN-γ/IL-4 ratio and persistence of Entamoeba histolytica during intestinal amebiasis.

Deloer S, Nakamura R, Kikuchi M, Moriyasu T, Kalenda YDJ, Mohammed ES, Senba M, Iwakura Y, Yoshida H, Hamano S.

Parasitol Int. 2017 Dec;66(6):817-823. doi: 10.1016/j.parint.2017.09.011. Epub 2017 Sep 18.

PMID:
28927906
35.

Interleukin-17A-Deficient Mice Are Highly Susceptible to Toxoplasma gondii Infection Due to Excessively Induced T. gondii HSP70 and Interferon Gamma Production.

Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F.

Infect Immun. 2017 Nov 17;85(12). pii: e00399-17. doi: 10.1128/IAI.00399-17. Print 2017 Dec.

36.

IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury.

Geha M, Tsokos MG, Bosse RE, Sannikova T, Iwakura Y, Dalle Lucca JJ, De Waal Malefyt R, Tsokos GC.

J Immunol. 2017 Oct 15;199(8):2921-2929. doi: 10.4049/jimmunol.1700655. Epub 2017 Sep 6.

37.

The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation.

Wang J, Ge P, Qiang L, Tian F, Zhao D, Chai Q, Zhu M, Zhou R, Meng G, Iwakura Y, Gao GF, Liu CH.

Nat Commun. 2017 Aug 15;8(1):244. doi: 10.1038/s41467-017-00279-z.

38.

Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.

Brown BR, Lee EJ, Snow PE, Vance EE, Iwakura Y, Ohno N, Miura N, Lin X, Brown GD, Wells CA, Smith JR, Caspi RR, Rosenzweig HL.

Clin Exp Immunol. 2017 Dec;190(3):293-303. doi: 10.1111/cei.13021. Epub 2017 Aug 30.

39.

An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells.

St Leger AJ, Desai JV, Drummond RA, Kugadas A, Almaghrabi F, Silver P, Raychaudhuri K, Gadjeva M, Iwakura Y, Lionakis MS, Caspi RR.

Immunity. 2017 Jul 18;47(1):148-158.e5. doi: 10.1016/j.immuni.2017.06.014. Epub 2017 Jul 11.

40.

Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis.

Maruyama K, Takayama Y, Kondo T, Ishibashi KI, Sahoo BR, Kanemaru H, Kumagai Y, Martino MM, Tanaka H, Ohno N, Iwakura Y, Takemura N, Tominaga M, Akira S.

Cell Rep. 2017 Jun 27;19(13):2730-2742. doi: 10.1016/j.celrep.2017.06.002.

41.

Striatal hypodopamine phenotypes found in transgenic mice that overexpress glial cell line-derived neurotrophic factor.

Sotoyama H, Iwakura Y, Oda K, Sasaoka T, Takei N, Kakita A, Enomoto H, Nawa H.

Neurosci Lett. 2017 Jul 27;654:99-106. doi: 10.1016/j.neulet.2017.06.005. Epub 2017 Jun 21.

PMID:
28645787
42.

Quantification of bleeding volume using computed tomography and clinical complications after percutaneous renal biopsy.

Chikamatsu Y, Matsuda K, Takeuchi Y, Kagaya S, Ojima Y, Fukami H, Sato H, Saito A, Iwakura Y, Nagasawa T.

Clin Kidney J. 2017 Feb;10(1):9-15. doi: 10.1093/ckj/sfw131. Epub 2017 Jan 25.

43.

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM.

J Neurosci. 2017 Jul 26;37(30):7125-7139. doi: 10.1523/JNEUROSCI.2519-16.2017. Epub 2017 Jun 21.

44.

Epidermal growth factor signals attenuate phenotypic and functional development of neocortical GABA neurons.

Namba H, Nagano T, Jodo E, Eifuku S, Horie M, Takebayashi H, Iwakura Y, Sotoyama H, Takei N, Nawa H.

J Neurochem. 2017 Jun 13. doi: 10.1111/jnc.14097. [Epub ahead of print]

45.

Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S.

Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12. Erratum in: Nat Med. 2017 Oct 6;23 (10 ):1241.

46.

Modulation of an innate immune response by soluble yeast β-glucan prepared by a heat degradation method.

Ishimoto Y, Ishibashi KI, Yamanaka D, Adachi Y, Kanzaki K, Okita K, Iwakura Y, Ohno N.

Int J Biol Macromol. 2017 Nov;104(Pt A):367-376. doi: 10.1016/j.ijbiomac.2017.06.036. Epub 2017 Jun 8.

PMID:
28602993
47.

Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.

Zhang C, Feng J, Du J, Zhuo Z, Yang S, Zhang W, Wang W, Zhang S, Iwakura Y, Meng G, Fu YX, Hou B, Tang H.

Cell Mol Immunol. 2018 Nov;15(11):973-982. doi: 10.1038/cmi.2017.22. Epub 2017 May 15.

PMID:
28504245
48.

Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity.

Kanemaru K, Nakamura Y, Totoki K, Fukuyama T, Shoji M, Kaneko H, Shiratori K, Yoneda A, Inoue T, Iwakura Y, Kabashima K, Fukami K.

Cell Death Differ. 2017 Jun;24(6):1079-1090. doi: 10.1038/cdd.2017.56. Epub 2017 Apr 21.

49.

Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis.

Morita M, Iwasaki R, Sato Y, Kobayashi T, Watanabe R, Oike T, Nakamura S, Keneko Y, Miyamoto K, Ishihara K, Iwakura Y, Ishii K, Matsumoto M, Nakamura M, Kawana H, Nakagawa T, Miyamoto T.

Sci Rep. 2017 Apr 7;7:46322. doi: 10.1038/srep46322.

50.

Megakaryocytes compensate for Kit insufficiency in murine arthritis.

Cunin P, Penke LR, Thon JN, Monach PA, Jones T, Chang MH, Chen MM, Melki I, Lacroix S, Iwakura Y, Ware J, Gurish MF, Italiano JE, Boilard E, Nigrovic PA.

J Clin Invest. 2017 May 1;127(5):1714-1724. doi: 10.1172/JCI84598. Epub 2017 Apr 4.

Supplemental Content

Loading ...
Support Center