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Items: 1 to 50 of 881

1.

Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCFFBXL5 ubiquitin ligase.

Iwai K.

Free Radic Biol Med. 2018 Sep 13. pii: S0891-5849(18)31589-2. doi: 10.1016/j.freeradbiomed.2018.09.011. [Epub ahead of print]

PMID:
30218771
2.

HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection.

MacDuff DA, Baldridge MT, Qaqish AM, Nice TJ, Darbandi AD, Hartley VL, Peterson ST, Miner JJ, Iwai K, Virgin HW.

J Virol. 2018 Sep 12. pii: JVI.01368-18. doi: 10.1128/JVI.01368-18. [Epub ahead of print]

PMID:
30209176
3.

An unusual manifestation of Sjögren syndrome encephalitis.

Iwai K, Amo K, Kuki I, Fukuoka M, Kim K, Yamairi C, Togawa M.

Brain Dev. 2018 Aug 28. pii: S0387-7604(18)30418-2. doi: 10.1016/j.braindev.2018.08.004. [Epub ahead of print]

PMID:
30170935
4.

CCN3 secreted by prostaglandin E2 inhibits intimal cushion formation in the rat ductus arteriosus.

Iwai K, Nagasawa K, Akaike T, Oshima T, Kato T, Minamisawa S.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):3242-3247. doi: 10.1016/j.bbrc.2018.08.138. Epub 2018 Aug 24.

PMID:
30149912
5.

Autopsied case of non-plaque-type dura mater graft-associated Creutzfeldt-Jakob disease presenting with extensive amyloid-β deposition.

Iwasaki Y, Imamura K, Iwai K, Kobayashi Y, Akagi A, Mimuro M, Miyahara H, Kitamoto T, Yoshida M.

Neuropathology. 2018 Oct;38(5):549-556. doi: 10.1111/neup.12503. Epub 2018 Aug 6.

PMID:
30084170
6.

Contributions to the team score by male wheelchair basketball players with different physical capacities at the Rio 2016 Paralympics.

Doi T, Mutsuzaki H, Tachibana K, Wadano Y, Iwai K.

J Phys Ther Sci. 2018 Jul;30(7):948-951. doi: 10.1589/jpts.30.948. Epub 2018 Jul 3.

7.

Conceptual frameworks of synthetic lethality in clear cell carcinoma of the ovary.

Kobayashi H, Kawahara N, Ogawa K, Yamada Y, Iwai K, Niiro E, Morioka S.

Biomed Rep. 2018 Aug;9(2):112-118. doi: 10.3892/br.2018.1114. Epub 2018 Jun 20. Review.

8.

Linear Polyubiquitination: A Crucial Regulator of NF-κB Activation.

Iwai K.

In: Nakao K, Minato N, Uemoto S, editors. Innovative Medicine: Basic Research and Development [Internet]. Tokyo: Springer; 2015.

9.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 Jun;10(6). pii: e8289. doi: 10.15252/emmm.201708289.

10.

Phosphine Induced Dimerization of Propargyl Alcohols Leading to Allyl Propargyl Ethers.

Iwai K, Yokoyama S, Asahara H, Nishiwaki N.

J Oleo Sci. 2018 Jun 1;67(6):773-778. doi: 10.5650/jos.ess17277. Epub 2018 May 15.

11.

Aceruloplasminemia with Abnormal Compound Heterozygous Mutations Developed Neurological Dysfunction during Phlebotomy Therapy.

Watanabe M, Ohyama K, Suzuki M, Nosaki Y, Hara T, Iwai K, Kono S, Miyajima H, Mokuno K.

Intern Med. 2018 Sep 15;57(18):2713-2718. doi: 10.2169/internalmedicine.9855-17. Epub 2018 Apr 27.

12.

Difference in contributions to the team's score in female wheelchair basketball at the 2016 Rio Paralympics by physical capability classification.

Doi T, Mutsuzaki H, Tachibana K, Wadano Y, Iwai K.

J Phys Ther Sci. 2018 Apr;30(4):500-503. doi: 10.1589/jpts.30.500. Epub 2018 Apr 13.

13.

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.

Fujita H, Tokunaga A, Shimizu S, Whiting AL, Aguilar-Alonso F, Takagi K, Walinda E, Sasaki Y, Shimokawa T, Mizushima T, Ohki I, Ariyoshi M, Tochio H, Bernal F, Shirakawa M, Iwai K.

Cell Rep. 2018 Apr 24;23(4):1192-1204. doi: 10.1016/j.celrep.2018.03.112.

14.

Crucial Role of Linear Ubiquitin Chain Assembly Complex-Mediated Inhibition of Programmed Cell Death in TLR4-Mediated B Cell Responses and B1b Cell Development.

Sasaki Y, Iwai K.

J Immunol. 2018 May 15;200(10):3438-3449. doi: 10.4049/jimmunol.1701526. Epub 2018 Apr 13.

PMID:
29654209
15.

Potential signaling pathways as therapeutic targets for overcoming chemoresistance in mucinous ovarian cancer.

Niiro E, Morioka S, Iwai K, Yamada Y, Ogawa K, Kawahara N, Kobayashi H.

Biomed Rep. 2018 Mar;8(3):215-223. doi: 10.3892/br.2018.1045. Epub 2018 Jan 17.

16.

[A case of Alexander disease with dropped head syndrome].

Maeda K, Iwai K, Kobayashi Y, Tsuji H, Yoshida T, Kobayashi Y.

Rinsho Shinkeigaku. 2018 Mar 28;58(3):198-201. doi: 10.5692/clinicalneurol.cn-001116. Epub 2018 Mar 28. Review. Japanese.

PMID:
29491332
17.

Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins.

Ogura M, Endo R, Ishikawa H, Takeda Y, Uchida T, Iwai K, Kobayashi K, Ishimori K.

J Inorg Biochem. 2018 May;182:238-248. doi: 10.1016/j.jinorgbio.2018.01.007. Epub 2018 Jan 9.

PMID:
29449016
18.

Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.

Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, Dawson TM, Takahashi R.

Stem Cell Reports. 2018 Feb 13;10(2):356-365. doi: 10.1016/j.stemcr.2017.12.001. Epub 2018 Jan 11.

19.

Preoperative assessment of pleural adhesion by Four-Dimensional Ultra-Low-Dose Computed Tomography (4D-ULDCT) with Adaptive Iterative Dose Reduction using Three-Dimensional processing (AIDR-3D).

Hashimoto M, Nagatani Y, Oshio Y, Nitta N, Yamashiro T, Tsukagoshi S, Ushio N, Mayumi M, Kimoto T, Igarashi T, Yoshigoe M, Iwai K, Tanaka K, Sato S, Sonoda A, Otani H, Murata K, Hanaoka J; investigators of ACTIve study group.

Eur J Radiol. 2018 Jan;98:179-186. doi: 10.1016/j.ejrad.2017.11.011. Epub 2017 Nov 21.

PMID:
29279160
20.

SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.

Tamiya H, Kim H, Klymenko O, Kim H, Feng Y, Zhang T, Han JY, Murao A, Snipas SJ, Jilaveanu L, Brown K, Kluger H, Zhang H, Iwai K, Ronai ZA.

J Clin Invest. 2018 Jan 2;128(1):517-530. doi: 10.1172/JCI95410. Epub 2017 Dec 11.

21.

Association between α-Klotho and Deep White Matter Lesions in the Brain: A Pilot Case Control Study Using Brain MRI.

Kuriyama N, Ozaki E, Mizuno T, Ihara M, Mizuno S, Koyama T, Matsui D, Watanabe I, Akazawa K, Takeda K, Takada A, Inaba M, Yamada S, Motoyama K, Takeshita W, Iwai K, Hashiguchi K, Kobayashi D, Kondo M, Tamura A, Yamada K, Nakagawa M, Watanabe Y.

J Alzheimers Dis. 2018;61(1):145-155. doi: 10.3233/JAD-170466.

PMID:
29154273
22.

HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.

Magnani ND, Dada LA, Queisser MA, Brazee PL, Welch LC, Anekalla KR, Zhou G, Vagin O, Misharin AV, Budinger GRS, Iwai K, Ciechanover AJ, Sznajder JI.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10178-E10186. doi: 10.1073/pnas.1713563114. Epub 2017 Nov 6.

23.

Sequential molecular changes and dynamic oxidative stress in high-grade serous ovarian carcinogenesis.

Kobayashi H, Ogawa K, Kawahara N, Iwai K, Niiro E, Morioka S, Yamada Y.

Free Radic Res. 2017 Oct;51(9-10):755-764. doi: 10.1080/10715762.2017.1383605. Epub 2017 Oct 11. Review.

PMID:
28931330
24.

Genetic Variants of RAMP2 and CLR are Associated with Stroke.

Koyama T, Kuriyama N, Ozaki E, Matsui D, Watanabe I, Takeshita W, Iwai K, Watanabe Y, Nakatochi M, Shimanoe C, Tanaka K, Oze I, Ito H, Uemura H, Katsuura-Kamano S, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Kawai S, Sasakabe T, Okada R, Hishida A, Naito M, Kuriki K, Endoh K, Furusyo N, Ikezaki H, Suzuki S, Hosono A, Mikami H, Nakamura Y, Kubo M, Wakai K.

J Atheroscler Thromb. 2017 Dec 1;24(12):1267-1281. doi: 10.5551/jat.41517. Epub 2017 Sep 14.

25.

Comparison of the Different Definition Criteria for the Diagnosis of Amniotic Fluid Embolism.

Kobayashi H, Akasaka J, Naruse K, Sado T, Tsunemi T, Niiro E, Iwai K.

J Clin Diagn Res. 2017 Jul;11(7):QC18-QC21. doi: 10.7860/JCDR/2017/26746.10283. Epub 2017 Jul 1.

26.

Isolation of Extracellular Vesicles in Saliva Using Density Gradient Ultracentrifugation.

Iwai K, Yamamoto S, Yoshida M, Shiba K.

Methods Mol Biol. 2017;1660:343-350. doi: 10.1007/978-1-4939-7253-1_27.

PMID:
28828669
27.

Droplet microfluidics for synthetic biology.

Gach PC, Iwai K, Kim PW, Hillson NJ, Singh AK.

Lab Chip. 2017 Oct 11;17(20):3388-3400. doi: 10.1039/c7lc00576h. Review.

28.

The conceptual advances of carcinogenic sequence model in high-grade serous ovarian cancer.

Kobayashi H, Iwai K, Niiro E, Morioka S, Yamada Y, Ogawa K, Kawahara N.

Biomed Rep. 2017 Sep;7(3):209-213. doi: 10.3892/br.2017.955. Epub 2017 Jul 27.

29.

Congenital fiber-type disproportion presenting as ventricular fibrillation.

Iwai K, Yoshida Y, Kazuta T, Suzuki T, Kuki I.

Pediatr Int. 2017 Sep;59(9):1025-1027. doi: 10.1111/ped.13339. Epub 2017 Aug 7. No abstract available.

PMID:
28786238
30.

Changes in skin structure of the Zip13-KO mouse by Makomo (Zizania latifolia) feeding.

Yamauchi T, Hirose T, Sato K, Iwai K, Takahashi N, Minaguchi J, Ueno T, Tangkawattana P, Takehana K.

J Vet Med Sci. 2017 Sep 29;79(9):1563-1568. doi: 10.1292/jvms.17-0206. Epub 2017 Aug 4.

31.

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.

Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, Iwai K, Saeki Y, Yoshimori T, Matsuda N, Tanaka K.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8574-8579. doi: 10.1073/pnas.1702615114. Epub 2017 Jul 25.

32.

3D Printed "Earable" Smart Devices for Real-Time Detection of Core Body Temperature.

Ota H, Chao M, Gao Y, Wu E, Tai LC, Chen K, Matsuoka Y, Iwai K, Fahad HM, Gao W, Nyein HYY, Lin L, Javey A.

ACS Sens. 2017 Jul 28;2(7):990-997. doi: 10.1021/acssensors.7b00247. Epub 2017 Jul 19.

PMID:
28721726
33.

Current status of tertiary debulking surgery and prognosis after secondary debulking surgery for recurrent Müllerian epithelial cancer in Japan: a retrospective analysis of 164 patients (KCOG-G1402).

Hirakawa T, Minaguchi T, Itani Y, Kasamatsu Y, Murase S, Sakurada S, Nagano H, Takehara K, Tsuruta T, Arakawa A, Kawano K, Tsubamoto H, Ushiwaka T, Mori T, Iwai K, Saito M, Morisawa H, Saito F, Yoshida K, Kaneuchi M, Sato H, Ito K, Nasu K.

World J Surg Oncol. 2017 Jul 17;15(1):132. doi: 10.1186/s12957-017-1200-x.

34.

Lifestyle Changes and Oxidative Stress in a High-incidence Area of Amyotrophic Lateral Sclerosis in the Southwestern Kii Peninsula, Japan.

Kihira T, Okamoto K, Sakurai I, Arakawa Y, Wakayama I, Takamiya K, Okumura R, Iinuma Y, Iwai K, Kokubo Y, Yoshida S.

Intern Med. 2017;56(12):1497-1506. doi: 10.2169/internalmedicine.56.8038. Epub 2017 Jun 15.

35.

Skin-mucous membrane disorder and therapeutic effect of pegylated liposomal doxorubicin in recurrent ovarian cancer.

Yamada Y, Kawaguchi R, Ito F, Iwai K, Niiro E, Shigetomi H, Tanase Y, Kobayashi H.

J Obstet Gynaecol Res. 2017 Jul;43(7):1194-1199. doi: 10.1111/jog.13334. Epub 2017 May 19.

PMID:
28544386
36.

2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.

Kurasawa O, Homma M, Oguro Y, Miyazaki T, Mori K, Uchiyama N, Iwai K, Ohashi A, Hara H, Yoshida S, Cho N.

Bioorg Med Chem. 2017 Jul 15;25(14):3658-3670. doi: 10.1016/j.bmc.2017.04.044. Epub 2017 May 2.

PMID:
28533114
37.

Influence of Oral Appliances for Mandibular Advancement on Dentitions Using a Strain Gauge Analysis: A Pilot Study.

Ueda H, Matsumura Y, Horihata A, Concepcion C, Iwai K, Tanimoto K.

Sleep Disord. 2017;2017:9097305. doi: 10.1155/2017/9097305. Epub 2017 Apr 3.

38.

Synthesis of Functionalized 3-Cyanoisoxazoles Using a Dianionic Reagent.

Iwai K, Asahara H, Nishiwaki N.

J Org Chem. 2017 May 19;82(10):5409-5415. doi: 10.1021/acs.joc.7b00811. Epub 2017 May 9.

PMID:
28471185
39.

"Direct MPR": A Useful Tool for Oblique CT Fluoroscopy-Assisted Puncture.

Sato R, Aramaki T, Yoza K, Iwai K, Moriguchi M, Asakura K, Endo M, Ito T.

Cardiovasc Intervent Radiol. 2017 Aug;40(8):1261-1266. doi: 10.1007/s00270-017-1642-0. Epub 2017 Apr 24.

PMID:
28439625
40.

Successful Long-term Management with a Single Administration of Tri-weekly Nab-paclitaxel in a Patient with Advanced Gastric Cancer with Peritoneal Dissemination.

Matano D, Moriwaki T, Tange Y, Niisato Y, Yamaura M, Nagase M, Suganuma D, Takagi Taketa K, Iwai K, Enami C, Yamamoto Y, Hyodo I.

Intern Med. 2017;56(8):921-923. doi: 10.2169/internalmedicine.56.7783. Epub 2017 Apr 15.

41.

Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.

Kurasawa O, Oguro Y, Miyazaki T, Homma M, Mori K, Iwai K, Hara H, Skene R, Hoffman I, Ohashi A, Yoshida S, Ishikawa T, Cho N.

Bioorg Med Chem. 2017 Apr 1;25(7):2133-2147. doi: 10.1016/j.bmc.2017.02.021. Epub 2017 Feb 16.

PMID:
28284870
42.

Association between loss of bone mass due to short sleep and leptin-sympathetic nervous system activity.

Kuriyama N, Inaba M, Ozaki E, Yoneda Y, Matsui D, Hashiguchi K, Koyama T, Iwai K, Watanabe I, Tanaka R, Omichi C, Mizuno S, Kurokawa M, Horii M, Niwa F, Iwasa K, Yamada S, Watanabe Y.

Arch Gerontol Geriatr. 2017 May - Jun;70:201-208. doi: 10.1016/j.archger.2017.02.005. Epub 2017 Feb 10.

PMID:
28214401
43.

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.

Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, Inoue JI.

PLoS Pathog. 2017 Jan 19;13(1):e1006162. doi: 10.1371/journal.ppat.1006162. eCollection 2017 Jan.

44.

Oleuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating β-adrenergic signaling.

Oi-Kano Y, Iwasaki Y, Nakamura T, Watanabe T, Goto T, Kawada T, Watanabe K, Iwai K.

J Nutr Biochem. 2017 Feb;40:209-218. doi: 10.1016/j.jnutbio.2016.11.009. Epub 2016 Nov 23.

PMID:
27951473
45.

Oral Cnm-positive Streptococcus Mutans Expressing Collagen Binding Activity is a Risk Factor for Cerebral Microbleeds and Cognitive Impairment.

Watanabe I, Kuriyama N, Miyatani F, Nomura R, Naka S, Nakano K, Ihara M, Iwai K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Tamura A, Mizuno T, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Tanaka T, Kanamura N, Friedland RP, Watanabe Y.

Sci Rep. 2016 Dec 9;6:38561. doi: 10.1038/srep38561.

46.
47.

Survival of mature T cells depends on signaling through HOIP.

Okamura K, Kitamura A, Sasaki Y, Chung DH, Kagami S, Iwai K, Yasutomo K.

Sci Rep. 2016 Oct 27;6:36135. doi: 10.1038/srep36135.

48.

Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.

Yamano E, Sugimoto M, Hirayama A, Kume S, Yamato M, Jin G, Tajima S, Goda N, Iwai K, Fukuda S, Yamaguti K, Kuratsune H, Soga T, Watanabe Y, Kataoka Y.

Sci Rep. 2016 Oct 11;6:34990. doi: 10.1038/srep34990.

49.

Asymmetrical and smaller size of trunk muscles in combat sports athletes with lumbar intervertebral disc degeneration.

Iwai K, Koyama K, Okada T, Nakazato K, Takahashi R, Matsumoto S, Yamamoto Y, Hiranuma K.

Springerplus. 2016 Sep 1;5(1):1474. doi: 10.1186/s40064-016-3155-8. eCollection 2016.

50.

Redox-dependent Regulation of Gluconeogenesis by a Novel Mechanism Mediated by a Peroxidatic Cysteine of Peroxiredoxin.

Irokawa H, Tachibana T, Watanabe T, Matsuyama Y, Motohashi H, Ogasawara A, Iwai K, Naganuma A, Kuge S.

Sci Rep. 2016 Sep 16;6:33536. doi: 10.1038/srep33536.

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