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Items: 29


A dataset describing a suite of novel antibody reagents for the RAS signaling network.

Schoenherr RM, Huang D, Voytovich UJ, Ivey RG, Kennedy JJ, Saul RG, Colantonio S, Roberts RR, Knotts JG, Kaczmarczyk JA, Perry C, Hewitt SM, Bocik W, Whiteley GR, Hiltke T, Boja ES, Rodriguez H, Whiteaker JR, Paulovich AG.

Sci Data. 2019 Aug 29;6(1):160. doi: 10.1038/s41597-019-0166-7.


pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.

Jones GN, Rooney C, Griffin N, Roudier M, Young LA, Garcia-Trinidad A, Hughes GD, Whiteaker JR, Wilson Z, Odedra R, Zhao L, Ivey RG, Howat WJ, Harrington EA, Barrett JC, Ramos-Montoya A, Lau A, Paulovich AG, Cadogan EB, Pierce AJ.

Br J Cancer. 2018 Nov;119(10):1233-1243. doi: 10.1038/s41416-018-0286-4. Epub 2018 Nov 2.


Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.

Salter AI, Ivey RG, Kennedy JJ, Voillet V, Rajan A, Alderman EJ, Voytovich UJ, Lin C, Sommermeyer D, Liu L, Whiteaker JR, Gottardo R, Paulovich AG, Riddell SR.

Sci Signal. 2018 Aug 21;11(544). pii: eaat6753. doi: 10.1126/scisignal.aat6753.


Targeted mass spectrometry enables robust quantification of FANCD2 mono-ubiquitination in response to DNA damage.

Whiteaker JR, Zhao L, Ivey RG, Sanchez-Bonilla M, Moore HD, Schoenherr RM, Yan P, Lin C, Shimamura A, Paulovich AG.

DNA Repair (Amst). 2018 May;65:47-53. doi: 10.1016/j.dnarep.2018.03.003. Epub 2018 Mar 21.


A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage.

Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG.

Radiat Res. 2018 May;189(5):505-518. doi: 10.1667/RR14963.1. Epub 2018 Feb 23.


Peptide Immunoaffinity Enrichment with Targeted Mass Spectrometry: Application to Quantification of ATM Kinase Phospho-Signaling.

Whiteaker JR, Zhao L, Schoenherr RM, Kennedy JJ, Ivey RG, Paulovich AG.

Methods Mol Biol. 2017;1599:197-213. doi: 10.1007/978-1-4939-6955-5_15.


Commercially available antibodies can be applied in quantitative multiplexed peptide immunoaffinity enrichment targeted mass spectrometry assays.

Schoenherr RM, Zhao L, Ivey RG, Voytovich UJ, Kennedy J, Yan P, Lin C, Whiteaker JR, Paulovich AG.

Proteomics. 2016 Aug;16(15-16):2141-5. doi: 10.1002/pmic.201500540. Epub 2016 May 23.


Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.

Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich UJ, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG.

Mol Cell Proteomics. 2016 Feb;15(2):726-39. doi: 10.1074/mcp.O115.054940. Epub 2015 Nov 30.


Antibody-Coupled Magnetic Beads Can Be Reused in Immuno-MRM Assays To Reduce Cost and Extend Antibody Supply.

Zhao L, Whiteaker JR, Voytovich UJ, Ivey RG, Paulovich AG.

J Proteome Res. 2015 Oct 2;14(10):4425-31. doi: 10.1021/acs.jproteome.5b00290. Epub 2015 Aug 31.


Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling.

Whiteaker JR, Zhao L, Yan P, Ivey RG, Voytovich UJ, Moore HD, Lin C, Paulovich AG.

Mol Cell Proteomics. 2015 Aug;14(8):2261-73. doi: 10.1074/mcp.O115.050351. Epub 2015 May 18.


The human salivary proteome is radiation responsive.

Moore HD, Ivey RG, Voytovich UJ, Lin C, Stirewalt DL, Pogosova-Agadjanyan EL, Paulovich AG.

Radiat Res. 2014 May;181(5):521-30. doi: 10.1667/RR13586.1. Epub 2014 Apr 10.


Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.

Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG.

Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8.


Multiplexed quantification of estrogen receptor and HER2/Neu in tissue and cell lysates by peptide immunoaffinity enrichment mass spectrometry.

Schoenherr RM, Whiteaker JR, Zhao L, Ivey RG, Trute M, Kennedy J, Voytovich UJ, Yan P, Lin C, Paulovich AG.

Proteomics. 2012 Apr;12(8):1253-60. doi: 10.1002/pmic.201100587.


Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA.

Ivey RG, Moore HD, Voytovich UJ, Thienes CP, Lorentzen TD, Pogosova-Agadjanyan EL, Frayo S, Izaguirre VK, Lundberg SJ, Hedin L, Badiozamani KR, Hoofnagle AN, Stirewalt DL, Wang P, Georges GE, Gopal AK, Paulovich AG.

Radiat Res. 2011 Mar;175(3):266-81. doi: 10.1667/RR2402.1. Epub 2010 Dec 20.


Antibody-based screen for ionizing radiation-dependent changes in the Mammalian proteome for use in biodosimetry.

Ivey RG, Subramanian O, Lorentzen TD, Paulovich AG.

Radiat Res. 2009 May;171(5):549-61. doi: 10.1667/RR1638.1.


Genomic analysis of the smallest giant virus--Feldmannia sp. virus 158.

Schroeder DC, Park Y, Yoon HM, Lee YS, Kang SW, Meints RH, Ivey RG, Choi TJ.

Virology. 2009 Feb 5;384(1):223-32. doi: 10.1016/j.virol.2008.10.040. Epub 2008 Dec 2.


Identification of two virus integration sites in the brown alga Feldmannia chromosome.

Meints RH, Ivey RG, Lee AM, Choi TJ.

J Virol. 2008 Feb;82(3):1407-13. Epub 2007 Nov 21.


Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer.

Whiteaker JR, Zhang H, Zhao L, Wang P, Kelly-Spratt KS, Ivey RG, Piening BD, Feng LC, Kasarda E, Gurley KE, Eng JK, Chodosh LA, Kemp CJ, McIntosh MW, Paulovich AG.

J Proteome Res. 2007 Oct;6(10):3962-75. Epub 2007 Aug 21.


Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa.

Raymond CK, Sims EH, Kas A, Spencer DH, Kutyavin TV, Ivey RG, Zhou Y, Kaul R, Clendenning JB, Olson MV.

J Bacteriol. 2002 Jul;184(13):3614-22.


A Feldmannia algal virus has two genome size-classes.

Ivey RG, Henry EC, Lee AM, Klepper L, Krueger SK, Meints RH.

Virology. 1996 Jun 15;220(2):267-73.


A brown algal virus genome contains a "RING" zinc finger motif.

Krueger SK, Ivey RG, Henry EC, Meints RH.

Virology. 1996 May 1;219(1):301-3.


Characterization of a repetitive DNA element in a brown algal virus.

Lee AM, Ivey RG, Henry EC, Meints RH.

Virology. 1995 Oct 1;212(2):474-80.


Cloning of a chromosomal gene required for phage infection of Lactococcus lactis subsp. lactis C2.

Geller BL, Ivey RG, Trempy JE, Hettinger-Smith B.

J Bacteriol. 1993 Sep;175(17):5510-9.


P300 response: habituation.

Ivey RG, Schmidt HB.

J Am Acad Audiol. 1993 May;4(3):182-8.


Middle-component AERs during backward masking.

Ivey RG, Goldstein R.

J Aud Res. 1984 Oct;24(4):279-97.


Clinical application of the auditory averaged electroencephalic response (AER).

Ivey RG.

J Ark Med Soc. 1979 Nov;76(6):229-31. No abstract available.


The acoustic reflex and temporary threshold shift: temporal characteristics.

Karlovich RS, Osier HA, Gutnick HN, Ivey RG, Wolf K, Schwimmer S, Strennen ML, Gerber J.

J Speech Hear Res. 1977 Sep;20(3):565-73.


Tympanometric curves and otosclerosis.

Ivey RG.

J Speech Hear Res. 1975 Sep;18(3):554-8.


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