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Items: 1 to 50 of 173

1.

Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.

Filbey KJ, Varyani F, Harcus Y, Hewitson JP, Smyth DJ, McSorley HJ, Ivens A, Nylén S, Rottenberg M, Löser S, Maizels RM.

Front Immunol. 2019 Oct 24;10:2375. doi: 10.3389/fimmu.2019.02375. eCollection 2019.

2.

Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei.

Cooper S, Wadsworth ES, Ochsenreiter T, Ivens A, Savill NJ, Schnaufer A.

Nucleic Acids Res. 2019 Oct 30. pii: gkz928. doi: 10.1093/nar/gkz928. [Epub ahead of print]

PMID:
31665448
3.

Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei.

McWilliam KR, Ivens A, Morrison LJ, Mugnier MR, Matthews KR.

Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22774-22782. doi: 10.1073/pnas.1912711116. Epub 2019 Oct 21.

4.

Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions.

Johnston H, Dickinson P, Ivens A, Buck AH, Levine RD, Remacle F, Campbell CJ.

Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19753-19759. doi: 10.1073/pnas.1909455116. Epub 2019 Sep 10.

PMID:
31506353
5.

1,25-Dihydroxyvitamin D3 Restrains CD4+ T Cell Priming Ability of CD11c+ Dendritic Cells by Upregulating Expression of CD31.

Saul L, Mair I, Ivens A, Brown P, Samuel K, Campbell JDM, Soong DY, Kamenjarin N, Mellanby RJ.

Front Immunol. 2019 Mar 28;10:600. doi: 10.3389/fimmu.2019.00600. eCollection 2019.

6.

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.

Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS.

Nat Immunol. 2019 May;20(5):571-580. doi: 10.1038/s41590-019-0352-y. Epub 2019 Apr 1.

PMID:
30936493
7.

Dynamics of Colon Monocyte and Macrophage Activation During Colitis.

Jones GR, Bain CC, Fenton TM, Kelly A, Brown SL, Ivens AC, Travis MA, Cook PC, MacDonald AS.

Front Immunol. 2018 Nov 27;9:2764. doi: 10.3389/fimmu.2018.02764. eCollection 2018.

8.

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development.

Silvester E, Ivens A, Matthews KR.

PLoS Negl Trop Dis. 2018 Oct 11;12(10):e0006863. doi: 10.1371/journal.pntd.0006863. eCollection 2018 Oct.

9.

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

McDonald L, Cayla M, Ivens A, Mony BM, MacGregor P, Silvester E, McWilliam K, Matthews KR.

PLoS Pathog. 2018 Jun 25;14(6):e1007145. doi: 10.1371/journal.ppat.1007145. eCollection 2018 Jun.

10.

Inhibition of Microprocessor Function during the Activation of the Type I Interferon Response.

Witteveldt J, Ivens A, Macias S.

Cell Rep. 2018 Jun 12;23(11):3275-3285. doi: 10.1016/j.celrep.2018.05.049.

11.

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.

Buckner MMC, Saw HTH, Osagie RN, McNally A, Ricci V, Wand ME, Woodford N, Ivens A, Webber MA, Piddock LJV.

MBio. 2018 Apr 24;9(2). pii: e02303-17. doi: 10.1128/mBio.02303-17.

12.

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus.

Smyth DJ, Harcus Y, White MPJ, Gregory WF, Nahler J, Stephens I, Toke-Bjolgerud E, Hewitson JP, Ivens A, McSorley HJ, Maizels RM.

Int J Parasitol. 2018 Apr;48(5):379-385. doi: 10.1016/j.ijpara.2017.12.004. Epub 2018 Mar 3.

13.

Genetic diversity and cross-species transmission of kobuviruses in Vietnam.

Lu L, Van Dung N, Ivens A, Bogaardt C, O'Toole A, Bryant JE, Carrique-Mas J, Van Cuong N, Anh PH, Rabaa MA, Tue NT, Thwaites GE, Baker S, Simmonds P, Woolhouse ME; VIZIONS Consortium.

Virus Evol. 2018 Feb 13;4(1):vey002. doi: 10.1093/ve/vey002. eCollection 2018 Jan.

14.

Can social partnerships influence the microbiome? Insights from ant farmers and their trophobiont mutualists.

Ivens ABF, Gadau A, Kiers ET, Kronauer DJC.

Mol Ecol. 2018 Apr;27(8):1898-1914. doi: 10.1111/mec.14506. Epub 2018 Mar 15.

15.

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM.

Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6.

16.

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.

Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP, Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA, Schwarze J, Ivens AC, Maizels RM, McSorley HJ.

Immunity. 2017 Oct 17;47(4):739-751.e5. doi: 10.1016/j.immuni.2017.09.015.

17.

An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.

Kelly S, Ivens A, Mott GA, O'Neill E, Emms D, Macleod O, Voorheis P, Tyler K, Clark M, Matthews J, Matthews K, Carrington M.

Genome Biol Evol. 2017 Aug 1;9(8):2093-2109. doi: 10.1093/gbe/evx152.

18.

Interspecies quorum sensing in co-infections can manipulate trypanosome transmission potential.

Silvester E, Young J, Ivens A, Matthews KR.

Nat Microbiol. 2017 Nov;2(11):1471-1479. doi: 10.1038/s41564-017-0014-5. Epub 2017 Sep 4.

19.

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium.

Wang-Kan X, Blair JMA, Chirullo B, Betts J, La Ragione RM, Ivens A, Ricci V, Opperman TJ, Piddock LJV.

MBio. 2017 Jul 18;8(4). pii: e00968-17. doi: 10.1128/mBio.00968-17.

20.

Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells.

Trüb M, Barr TA, Morrison VL, Brown S, Caserta S, Rixon J, Ivens A, Gray D.

Front Immunol. 2017 Apr 28;8:489. doi: 10.3389/fimmu.2017.00489. eCollection 2017.

21.

Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei.

Rico E, Ivens A, Glover L, Horn D, Matthews KR.

PLoS Pathog. 2017 Mar 23;13(3):e1006279. doi: 10.1371/journal.ppat.1006279. eCollection 2017 Mar.

22.

Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.

Buckner MM, Blair JM, La Ragione RM, Newcombe J, Dwyer DJ, Ivens A, Piddock LJ.

MBio. 2016 Nov 22;7(6). pii: e01916-16. doi: 10.1128/mBio.01916-16.

23.

Erratum for Richmond et al., The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.

Richmond GE, Evans LP, Anderson MJ, Wand ME, Bonney LC, Ivens A, Chua KL, Webber MA, Sutton JM, Peterson ML, Piddock LJ.

MBio. 2016 Jun 21;7(3). pii: e00852-16. doi: 10.1128/mBio.00852-16. No abstract available.

24.

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines.

Campino S, Benavente ED, Assefa S, Thompson E, Drought LG, Taylor CJ, Gorvett Z, Carret CK, Flueck C, Ivens AC, Kwiatkowski DP, Alano P, Baker DA, Clark TG.

Malar J. 2016 Apr 21;15:229. doi: 10.1186/s12936-016-1254-1.

25.

The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.

Richmond GE, Evans LP, Anderson MJ, Wand ME, Bonney LC, Ivens A, Chua KL, Webber MA, Sutton JM, Peterson ML, Piddock LJ.

MBio. 2016 Apr 19;7(2):e00430-16. doi: 10.1128/mBio.00430-16. Erratum in: MBio. 2016;7(3). pii: e00852-16. doi: 10.1128/mBio.00852-16.

26.

Studying the Complex Communities of Ants and Their Symbionts Using Ecological Network Analysis.

Ivens AB, von Beeren C, Blüthgen N, Kronauer DJ.

Annu Rev Entomol. 2016;61:353-71. doi: 10.1146/annurev-ento-010715-023719. Review.

PMID:
26982442
27.

Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAs.

Miesen P, Ivens A, Buck AH, van Rij RP.

PLoS Negl Trop Dis. 2016 Feb 25;10(2):e0004452. doi: 10.1371/journal.pntd.0004452. eCollection 2016 Feb.

28.

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.

Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JM, Allen L, Glykofrydis F, Subramani C, Armesilla-Diaz A, Post AE, Schaak K, Gezer D, So CW, Holyoake TL, Wood A, O'Carroll D, Ratcliffe PJ, Kranc KR.

J Exp Med. 2015 Dec 14;212(13):2223-34. doi: 10.1084/jem.20150452. Epub 2015 Dec 7.

29.

Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.

Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, Kumar S, Abreu-Goodger C, Lear M, Harcus Y, Ceroni A, Babayan SA, Blaxter M, Ivens A, Maizels RM.

Nat Commun. 2015 Oct 22;6:8772. doi: 10.1038/ncomms9772. No abstract available.

30.

Whole blood gene expression profiling of neonates with confirmed bacterial sepsis.

Dickinson P, Smith CL, Forster T, Craigon M, Ross AJ, Khondoker MR, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Genom Data. 2014 Nov 15;3:41-8. doi: 10.1016/j.gdata.2014.11.003. eCollection 2015 Mar.

31.

Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni.

Nowacki FC, Swain MT, Klychnikov OI, Niazi U, Ivens A, Quintana JF, Hensbergen PJ, Hokke CH, Buck AH, Hoffmann KF.

J Extracell Vesicles. 2015 Oct 5;4:28665. doi: 10.3402/jev.v4.28665. eCollection 2015.

32.

Quantitative Analysis of MicroRNAs in Vaccinia virus Infection Reveals Diversity in Their Susceptibility to Modification and Suppression.

Buck AH, Ivens A, Gordon K, Craig N, Houzelle A, Roche A, Turnbull N, Beard PM.

PLoS One. 2015 Jul 10;10(7):e0131787. doi: 10.1371/journal.pone.0131787. eCollection 2015.

33.

Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children.

Kay GL, Millard A, Sergeant MJ, Midzi N, Gwisai R, Mduluza T, Ivens A, Nausch N, Mutapi F, Pallen M.

PLoS Negl Trop Dis. 2015 Jun 26;9(6):e0003861. doi: 10.1371/journal.pntd.0003861. eCollection 2015. Erratum in: PLoS Negl Trop Dis. 2015 Jul;9(7):e0003969.

34.

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, Thomas GD, Grainger JR, Selfridge J, McKenzie AN, Allen JE, Fagerholm SC, Maizels RM, Ivens AC, Bird A, MacDonald AS.

Nat Commun. 2015 Apr 24;6:6920. doi: 10.1038/ncomms7920.

35.

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Jones LH, Cook PC, Ivens AC, Thomas GD, Phythian-Adams AT, Allen JE, MacDonald AS.

Int Immunol. 2015 Nov;27(11):589-96. doi: 10.1093/intimm/dxv020. Epub 2015 Apr 20.

36.

NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.

Bühlmann M, Walrad P, Rico E, Ivens A, Capewell P, Naguleswaran A, Roditi I, Matthews KR.

Nucleic Acids Res. 2015 May 19;43(9):4491-504. doi: 10.1093/nar/gkv330. Epub 2015 Apr 14.

37.

A novel gene amplification causes upregulation of the PatAB ABC transporter and fluoroquinolone resistance in Streptococcus pneumoniae.

Baylay AJ, Ivens A, Piddock LJ.

Antimicrob Agents Chemother. 2015;59(6):3098-108. doi: 10.1128/AAC.04858-14. Epub 2015 Mar 16.

38.

Extracellular Onchocerca-derived small RNAs in host nodules and blood.

Quintana JF, Makepeace BL, Babayan SA, Ivens A, Pfarr KM, Blaxter M, Debrah A, Wanji S, Ngangyung HF, Bah GS, Tanya VN, Taylor DW, Hoerauf A, Buck AH.

Parasit Vectors. 2015 Jan 27;8:58. doi: 10.1186/s13071-015-0656-1.

39.

Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty.

Carnes J, Anupama A, Balmer O, Jackson A, Lewis M, Brown R, Cestari I, Desquesnes M, Gendrin C, Hertz-Fowler C, Imamura H, Ivens A, Kořený L, Lai DH, MacLeod A, McDermott SM, Merritt C, Monnerat S, Moon W, Myler P, Phan I, Ramasamy G, Sivam D, Lun ZR, Lukeš J, Stuart K, Schnaufer A.

PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3404. doi: 10.1371/journal.pntd.0003404. eCollection 2015 Jan.

40.

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.

Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, Kumar S, Abreu-Goodger C, Lear M, Harcus Y, Ceroni A, Babayan SA, Blaxter M, Ivens A, Maizels RM.

Nat Commun. 2014 Nov 25;5:5488. doi: 10.1038/ncomms6488. Erratum in: Nat Commun. 2015;6:8772.

41.

Identification of a human neonatal immune-metabolic network associated with bacterial infection.

Smith CL, Dickinson P, Forster T, Craigon M, Ross A, Khondoker MR, France R, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Nat Commun. 2014 Aug 14;5:4649. doi: 10.1038/ncomms5649.

42.

Genomic analysis of the causative agents of coccidiosis in domestic chickens.

Reid AJ, Blake DP, Ansari HR, Billington K, Browne HP, Bryant J, Dunn M, Hung SS, Kawahara F, Miranda-Saavedra D, Malas TB, Mourier T, Naghra H, Nair M, Otto TD, Rawlings ND, Rivailler P, Sanchez-Flores A, Sanders M, Subramaniam C, Tay YL, Woo Y, Wu X, Barrell B, Dear PH, Doerig C, Gruber A, Ivens AC, Parkinson J, Rajandream MA, Shirley MW, Wan KL, Berriman M, Tomley FM, Pain A.

Genome Res. 2014 Oct;24(10):1676-85. doi: 10.1101/gr.168955.113. Epub 2014 Jul 11.

43.

Combinatorial communication in bacteria: implications for the origins of linguistic generativity.

Scott-Phillips TC, Gurney J, Ivens A, Diggle SP, Popat R.

PLoS One. 2014 Apr 23;9(4):e95929. doi: 10.1371/journal.pone.0095929. eCollection 2014.

44.

Combinatorial quorum sensing allows bacteria to resolve their social and physical environment.

Cornforth DM, Popat R, McNally L, Gurney J, Scott-Phillips TC, Ivens A, Diggle SP, Brown SP.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4280-4. doi: 10.1073/pnas.1319175111. Epub 2014 Mar 4.

45.

Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection.

Hoy AM, Lundie RJ, Ivens A, Quintana JF, Nausch N, Forster T, Jones F, Kabatereine NB, Dunne DW, Mutapi F, Macdonald AS, Buck AH.

PLoS Negl Trop Dis. 2014 Feb 20;8(2):e2701. doi: 10.1371/journal.pntd.0002701. eCollection 2014 Feb.

46.

Evolution of microbial markets.

Werner GD, Strassmann JE, Ivens AB, Engelmoer DJ, Verbruggen E, Queller DC, Noë R, Johnson NC, Hammerstein P, Kiers ET.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1237-44. doi: 10.1073/pnas.1315980111. Epub 2014 Jan 13.

47.

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

MacGregor P, Ivens A, Shave S, Collie I, Gray D, Auer M, Matthews KR.

Eukaryot Cell. 2014 Mar;13(3):412-26. doi: 10.1128/EC.00335-13. Epub 2014 Jan 17.

48.

A draft genome for the African crocodilian trypanosome Trypanosoma grayi.

Kelly S, Ivens A, Manna PT, Gibson W, Field MC.

Sci Data. 2014 Aug 5;1:140024. doi: 10.1038/sdata.2014.24. eCollection 2014.

49.

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei.

Mony BM, MacGregor P, Ivens A, Rojas F, Cowton A, Young J, Horn D, Matthews K.

Nature. 2014 Jan 30;505(7485):681-685. doi: 10.1038/nature12864. Epub 2013 Dec 15.

50.

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.

Hewitson JP, Ivens AC, Harcus Y, Filbey KJ, McSorley HJ, Murray J, Bridgett S, Ashford D, Dowle AA, Maizels RM.

PLoS Pathog. 2013 Aug;9(8):e1003492. doi: 10.1371/journal.ppat.1003492. Epub 2013 Aug 15.

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