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Items: 28


Clinical Pharmacology Driven Translational Research to Optimize Bedside Therapeutics of Sotalol Therapy.

Dahmane E, Tang K, Gobburu JVS, Joseph Mattingly T II, Reed BN, See VY, Ayres J, Ivaturi V.

Clin Transl Sci. 2019 Jul 22. doi: 10.1111/cts.12670. [Epub ahead of print]


Population Pharmacokinetic Modeling of Gentamicin in Pediatrics.

Wang H, Sherwin C, Gobburu JVS, Ivaturi V.

J Clin Pharmacol. 2019 Jul 8. doi: 10.1002/jcph.1479. [Epub ahead of print]


Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study.

Mehta K, Ravimohan S, Pasipanodya JG, Srivastava S, Modongo C, Zetola NM, Weissman D, Ivaturi V, Gumbo T, Bisson GP, Vinnard C.

J Antimicrob Chemother. 2019 Jul 4. pii: dkz265. doi: 10.1093/jac/dkz265. [Epub ahead of print]


Could Postnatal Age-Related Uridine Diphosphate Glucuronic Acid Be a Rate-Limiting Factor in the Metabolism of Morphine During the First Week of Life?

Liu T, Lewis TR, Moore JN, Kraft WK, Gauda EB, Sartori D, Moody DE, Gobburu JVS, Ivaturi V.

CPT Pharmacometrics Syst Pharmacol. 2019 May 1. doi: 10.1002/psp4.12407. [Epub ahead of print]


Population Pharmacokinetics of Clofarabine as Part of Pretransplantation Conditioning in Pediatric Subjects before Hematopoietic Cell Transplantation.

Wang H, Jones AK, Dvorak CC, Huang L, Orchard P, Ivaturi V, Long-Boyle J.

Biol Blood Marrow Transplant. 2019 Apr 17. pii: S1083-8791(19)30240-X. doi: 10.1016/j.bbmt.2019.04.017. [Epub ahead of print]


Integrated Model to Describe Morphine Pharmacokinetics in Humans.

Liu T, Ivaturi V, Gobburu J.

J Clin Pharmacol. 2019 Aug;59(8):1070-1077. doi: 10.1002/jcph.1400. Epub 2019 Mar 6.


Population Pharmacokinetic Assessment of Vancomycin Dosing in the Large Pediatric Patient.

Moffett BS, Ivaturi V, Morris J, Akcan Arikan A, Dutta A.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02359-18. doi: 10.1128/AAC.02359-18. Print 2019 Apr.


Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.

Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E.

PLoS Biol. 2019 Jan 24;17(1):e3000119. doi: 10.1371/journal.pbio.3000119. eCollection 2019 Jan.


Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis.

Tucker EW, Guglieri-Lopez B, Ordonez AA, Ritchie B, Klunk MH, Sharma R, Chang YS, Sanchez-Bautista J, Frey S, Lodge MA, Rowe SP, Holt DP, Gobburu JVS, Peloquin CA, Mathews WB, Dannals RF, Pardo CA, Kannan S, Ivaturi VD, Jain SK.

Sci Transl Med. 2018 Dec 5;10(470). pii: eaau0965. doi: 10.1126/scitranslmed.aau0965.


Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.

Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E.

PLoS Biol. 2018 Oct 18;16(10):e2005924. doi: 10.1371/journal.pbio.2005924. eCollection 2018 Oct. Erratum in: PLoS Biol. 2019 Jan 24;17(1):e3000119.


Systemic Octreotide Therapy in Prevention of Gastrointestinal Bleeds Related to Arteriovenous Malformations and Obscure Etiology in Atrial Fibrillation.

Vuddanda V, Jazayeri MA, Turagam MK, Lavu M, Parikh V, Atkins D, Bommana S, Yeruva MR, Di Biase L, Cheng J, Swarup V, Gopinathannair R, Olyaee M, Ivaturi V, Natale A, Lakkireddy D.

JACC Clin Electrophysiol. 2017 Dec 11;3(12):1390-1399. doi: 10.1016/j.jacep.2017.04.022. Epub 2017 Sep 13.


Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship.

Liu T, Ivaturi V, Sabato P, Gobburu JVS, Greer JM, Wright JJ, Smith BD, Pratz KW, Rudek MA; ETCTN-6745 study team.

Clin Transl Sci. 2018 Jul;11(4):435-443. doi: 10.1111/cts.12555. Epub 2018 Apr 27. Erratum in: Clin Transl Sci. 2018 Nov;11(6):624.


Observation of Patients Transitioned to an Oral Loop Diuretic Before Discharge and Risk of Readmission for Acute Decompensated Heart Failure.

Laliberte B, Reed BN, Devabhakthuni S, Watson K, Ivaturi V, Liu T, Gottlieb SS.

J Card Fail. 2017 Oct;23(10):746-752. doi: 10.1016/j.cardfail.2017.06.008. Epub 2017 Jul 5.


Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients.

Ivaturi V, Dvorak CC, Chan D, Liu T, Cowan MJ, Wahlstrom J, Stricherz M, Jennissen C, Orchard PJ, Tolar J, Pai SY, Huang L, Aweeka F, Long-Boyle J.

Biol Blood Marrow Transplant. 2017 Oct;23(10):1701-1713. doi: 10.1016/j.bbmt.2017.06.021. Epub 2017 Jul 3.


Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types.

Niu J, Scheuerell C, Mehrotra S, Karan S, Puhalla S, Kiesel BF, Ji J, Chu E, Gopalakrishnan M, Ivaturi V, Gobburu J, Beumer JH.

J Clin Pharmacol. 2017 Aug;57(8):977-987. doi: 10.1002/jcph.892. Epub 2017 Apr 7.


Valacyclovir as Initial Treatment for Acute Retinal Necrosis: A Pharmacokinetic Modeling and Simulation Study.

Liu T, Jain A, Fung M, Vinnard C, Ivaturi V.

Curr Eye Res. 2017 Jul;42(7):1035-1038. doi: 10.1080/02713683.2016.1231323. Epub 2017 Mar 30.


Exposure-Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients.

LaCerte C, Ivaturi V, Gobburu J, Greer JM, Doyle LA, Wright JJ, Karp JE, Rudek MA.

Clin Cancer Res. 2017 Jul 15;23(14):3592-3600. doi: 10.1158/1078-0432.CCR-16-2629. Epub 2017 Feb 7.


Exposure-response analysis after subcutaneous administration of RBP-7000, a once-a-month long-acting Atrigel formulation of risperidone.

Ivaturi V, Gopalakrishnan M, Gobburu JVS, Zhang W, Liu Y, Heidbreder C, Laffont CM.

Br J Clin Pharmacol. 2017 Jul;83(7):1476-1498. doi: 10.1111/bcp.13246. Epub 2017 Mar 31.


Diltiazem versus metoprolol for rate control in atrial fibrillation with rapid ventricular response in the emergency department.

Hines MC, Reed BN, Ivaturi V, Bontempo LJ, Bond MC, Hayes BD.

Am J Health Syst Pharm. 2016 Dec 15;73(24):2068-2076.


Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation.

Vinnard C, Ravimohan S, Tamuhla N, Ivaturi V, Pasipanodya J, Srivastava S, Modongo C, Zetola NM, Weissman D, Gumbo T, Bisson GP.

Br J Clin Pharmacol. 2017 Apr;83(4):801-811. doi: 10.1111/bcp.13172. Epub 2016 Dec 9.


Efficacy and Safety of Intravenous Chlorothiazide versus Oral Metolazone in Patients with Acute Decompensated Heart Failure and Loop Diuretic Resistance.

Shulenberger CE, Jiang A, Devabhakthuni S, Ivaturi V, Liu T, Reed BN.

Pharmacotherapy. 2016 Aug;36(8):852-60. doi: 10.1002/phar.1798. Epub 2016 Jul 29.


Urine colorimetry to detect Low rifampin exposure during tuberculosis therapy: a proof-of-concept study.

Zentner I, Schlecht HP, Khensouvann L, Tamuhla N, Kutzler M, Ivaturi V, Pasipanodya JG, Gumbo T, Peloquin CA, Bisson GP, Vinnard C.

BMC Infect Dis. 2016 Jun 1;16:242. doi: 10.1186/s12879-016-1576-1.


Mechanistic Population Pharmacokinetics of Morphine in Neonates With Abstinence Syndrome After Oral Administration of Diluted Tincture of Opium.

Liu T, Lewis T, Gauda E, Gobburu J, Ivaturi V.

J Clin Pharmacol. 2016 Aug;56(8):1009-18. doi: 10.1002/jcph.696. Epub 2016 Feb 22.


A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers.

Agarwal SK, Kriel RL, Brundage RC, Ivaturi VD, Cloyd JC.

Epilepsy Res. 2013 Aug;105(3):362-7. doi: 10.1016/j.eplepsyres.2013.02.018. Epub 2013 Apr 2.


Bioavailability of intranasal vs. rectal diazepam.

Ivaturi V, Kriel R, Brundage R, Loewen G, Mansbach H, Cloyd J.

Epilepsy Res. 2013 Feb;103(2-3):254-61. doi: 10.1016/j.eplepsyres.2012.07.018. Epub 2012 Sep 13.


Pharmacokinetics and tolerability of intranasal diazepam and midazolam in healthy adult volunteers.

Ivaturi VD, Riss JR, Kriel RL, Cloyd JC.

Acta Neurol Scand. 2009 Nov;120(5):353-7. doi: 10.1111/j.1600-0404.2009.01170.x. Epub 2009 May 14.


Bioavailability and tolerability of intranasal diazepam in healthy adult volunteers.

Ivaturi VD, Riss JR, Kriel RL, Siegel RA, Cloyd JC.

Epilepsy Res. 2009 Apr;84(2-3):120-6. doi: 10.1016/j.eplepsyres.2009.01.001. Epub 2009 Feb 20.


Enhanced permeation of methotrexate in vitro by ion pair formation with L-arginine.

Ivaturi VD, Kim SK.

J Pharm Sci. 2009 Oct;98(10):3633-9. doi: 10.1002/jps.21663.


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