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Items: 1 to 50 of 123

1.

Filopodia Quantification Using FiloQuant.

Jacquemet G, Hamidi H, Ivaska J.

Methods Mol Biol. 2019;2040:359-373. doi: 10.1007/978-1-4939-9686-5_16.

PMID:
31432487
2.

A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites.

McCormick B, Craig HE, Chu JY, Carlin LM, Canel M, Wollweber F, Toivakka M, Michael M, Astier AL, Norton L, Lilja J, Felton JM, Sasaki T, Ivaska J, Hers I, Dransfield I, Rossi AG, Vermeren S.

J Immunol. 2019 Aug 19. pii: ji1900443. doi: 10.4049/jimmunol.1900443. [Epub ahead of print]

PMID:
31427445
3.

Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes.

Kähäri L, Fair-Mäkelä R, Auvinen K, Rantakari P, Jalkanen S, Ivaska J, Salmi M.

J Clin Invest. 2019 Jun 24;129(8):3086-3102. doi: 10.1172/JCI125740. eCollection 2019 Jun 24.

4.

Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops.

Czechowska K, Lannigan J, Wang L, Arcidiacono J, Ashhurst TM, Barnard RM, Bauer S, Bispo C, Bonilla DL, Brinkman RR, Cabanski M, Chang HD, Chakrabarti L, Chojnowski G, Cotleur B, Degheidy H, Dela Cruz GV, Eck S, Elliott J, Errington R, Filby A, Gagnon D, Gardner R, Green C, Gregory M, Groves CJ, Hall C, Hammes F, Hedrick M, Hoffman R, Icha J, Ivaska J, Jenner DC, Jones D, Kerckhof FM, Kukat C, Lanham D, Leavesley S, Lee M, Lin-Gibson S, Litwin V, Liu Y, Molloy J, Moore JS, Müller S, Nedbal J, Niesner R, Nitta N, Ohlsson-Wilhelm B, Paul NE, Perfetto S, Portat Z, Props R, Radtke S, Rayanki R, Rieger A, Rogers S, Rubbens P, Salomon R, Schiemann M, Sharpe J, Sonder SU, Stewart JJ, Sun Y, Ulrich H, Van Isterdael G, Vitaliti A, van Vreden C, Weber M, Zimmermann J, Vacca G, Wallace P, Tárnok A.

Cytometry A. 2019 Jun;95(6):598-644. doi: 10.1002/cyto.a.23777. No abstract available.

PMID:
31207046
5.

Integrins as biomechanical sensors of the microenvironment.

Kechagia JZ, Ivaska J, Roca-Cusachs P.

Nat Rev Mol Cell Biol. 2019 Aug;20(8):457-473. doi: 10.1038/s41580-019-0134-2. Review.

PMID:
31182865
6.

SORLA regulates endosomal trafficking and oncogenic fitness of HER2.

Pietilä M, Sahgal P, Peuhu E, Jäntti NZ, Paatero I, Närvä E, Al-Akhrass H, Lilja J, Georgiadou M, Andersen OM, Padzik A, Sihto H, Joensuu H, Blomqvist M, Saarinen I, Boström PJ, Taimen P, Ivaska J.

Nat Commun. 2019 May 28;10(1):2340. doi: 10.1038/s41467-019-10275-0.

7.

GGA2 and RAB13 promote activity-dependent β1-integrin recycling.

Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, Pietilä M, Rokka A, Ivaska J.

J Cell Sci. 2019 Jun 7;132(11). pii: jcs233387. doi: 10.1242/jcs.233387.

PMID:
31076515
8.

68Ga-DOTA-E[c(RGDfK)]2 Positron Emission Tomography Imaging of SHARPIN-Regulated Integrin Activity in Mice.

Siitonen R, Peuhu E, Autio AK, Liljenbäck H, Mattila E, Metsälä O, Käkelä M, Saanijoki T, Dijkgraaf I, Jalkanen S, Ivaska J, Roivainen A.

J Nucl Med. 2019 Mar 8. pii: jnumed.118.222026. doi: 10.2967/jnumed.118.222026. [Epub ahead of print]

PMID:
30850498
9.

Integrin signaling and mechanotransduction in regulation of somatic stem cells.

Isomursu A, Lerche M, Taskinen ME, Ivaska J, Peuhu E.

Exp Cell Res. 2019 May 15;378(2):217-225. doi: 10.1016/j.yexcr.2019.01.027. Epub 2019 Feb 25. Review.

PMID:
30817927
10.

Author Correction: Every step of the way: integrins in cancer progression and metastasis.

Hamidi H, Ivaska J.

Nat Rev Cancer. 2019 Mar;19(3):179. doi: 10.1038/s41568-019-0112-1.

PMID:
30705430
11.

Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability.

Jacquemet G, Stubb A, Saup R, Miihkinen M, Kremneva E, Hamidi H, Ivaska J.

Curr Biol. 2019 Jan 21;29(2):202-216.e7. doi: 10.1016/j.cub.2018.11.053. Epub 2019 Jan 10.

12.

Integrin trafficking in cells and tissues.

Moreno-Layseca P, Icha J, Hamidi H, Ivaska J.

Nat Cell Biol. 2019 Feb;21(2):122-132. doi: 10.1038/s41556-018-0223-z. Epub 2019 Jan 2. Review.

13.

Editorial overview: Cell architecture: Integrating physics and chemistry in emergent cellular properties.

Ivaska J, Théry M.

Curr Opin Cell Biol. 2019 Feb;56:iii-iv. doi: 10.1016/j.ceb.2018.12.003. Epub 2018 Dec 21. No abstract available.

PMID:
30583915
14.

ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes.

De Franceschi N, Miihkinen M, Hamidi H, Alanko J, Mai A, Picas L, Guzmán C, Lévy D, Mattjus P, Goult BT, Goud B, Ivaska J.

J Cell Sci. 2018 Aug 20;132(4). pii: jcs214270. doi: 10.1242/jcs.214270.

15.

Every step of the way: integrins in cancer progression and metastasis.

Hamidi H, Ivaska J.

Nat Rev Cancer. 2018 Sep;18(9):533-548. doi: 10.1038/s41568-018-0038-z. Review. Erratum in: Nat Rev Cancer. 2019 Mar;19(3):179.

16.

Targeting β1-integrin inhibits vascular leakage in endotoxemia.

Hakanpaa L, Kiss EA, Jacquemet G, Miinalainen I, Lerche M, Guzmán C, Mervaala E, Eklund L, Ivaska J, Saharinen P.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6467-E6476. doi: 10.1073/pnas.1722317115. Epub 2018 Jun 25.

17.

Integrin activity in neuronal connectivity.

Lilja J, Ivaska J.

J Cell Sci. 2018 Jun 15;131(12). pii: jcs212803. doi: 10.1242/jcs.212803. Review.

18.

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation.

Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti-Bugaeva O, Paatero I, Niiranen O, Tuohinto K, Perälä N, Taiwo A, Zinovkina N, Repo P, Icay K, Ivaska J, Saharinen P, Hautaniemi S, Lehti K, Ojala PM.

Elife. 2018 May 1;7. pii: e32490. doi: 10.7554/eLife.32490.

19.

Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing Cells.

Jacquemet G, Ivaska J.

Dev Cell. 2018 Apr 9;45(1):5-7. doi: 10.1016/j.devcel.2018.03.015.

20.

Using xCELLigence RTCA Instrument to Measure Cell Adhesion.

Hamidi H, Lilja J, Ivaska J.

Bio Protoc. 2017 Dec 20;7(24). pii: e2646. doi: 10.21769/BioProtoc.2646.

21.

Loss of ADAM9 expression impairs β1 integrin endocytosis, focal adhesion formation and cancer cell migration.

Mygind KJ, Schwarz J, Sahgal P, Ivaska J, Kveiborg M.

J Cell Sci. 2018 Jan 4;131(1). pii: jcs205393. doi: 10.1242/jcs.205393.

22.

Cell-derived matrices for studying cell proliferation and directional migration in a complex 3D microenvironment.

Kaukonen R, Jacquemet G, Hamidi H, Ivaska J.

Nat Protoc. 2017 Nov;12(11):2376-2390. doi: 10.1038/nprot.2017.107. Epub 2017 Oct 19.

PMID:
29048422
23.

Epithelial vimentin plays a functional role in mammary gland development.

Peuhu E, Virtakoivu R, Mai A, Wärri A, Ivaska J.

Development. 2017 Nov 15;144(22):4103-4113. doi: 10.1242/dev.154229. Epub 2017 Sep 25.

24.

Concordance of the new ESPEN criteria with low phase angle in defining early stages of malnutrition in cardiac surgery.

Ringaitiene D, Gineityte D, Vicka V, Sabestinaite A, Klimasauskas A, Gaveliene E, Rucinskas K, Ivaska J, Sipylaite J.

Clin Nutr. 2018 Oct;37(5):1596-1601. doi: 10.1016/j.clnu.2017.08.007. Epub 2017 Aug 12.

PMID:
28843445
25.

FiloQuant reveals increased filopodia density during breast cancer progression.

Jacquemet G, Paatero I, Carisey AF, Padzik A, Orange JS, Hamidi H, Ivaska J.

J Cell Biol. 2017 Oct 2;216(10):3387-3403. doi: 10.1083/jcb.201704045. Epub 2017 Aug 1.

26.

Tensins: Bridging AMP-Activated Protein Kinase with Integrin Activation.

Georgiadou M, Ivaska J.

Trends Cell Biol. 2017 Oct;27(10):703-711. doi: 10.1016/j.tcb.2017.06.004. Epub 2017 Jul 8. Review.

PMID:
28698049
27.

A Strong Contractile Actin Fence and Large Adhesions Direct Human Pluripotent Colony Morphology and Adhesion.

Närvä E, Stubb A, Guzmán C, Blomqvist M, Balboa D, Lerche M, Saari M, Otonkoski T, Ivaska J.

Stem Cell Reports. 2017 Jul 11;9(1):67-76. doi: 10.1016/j.stemcr.2017.05.021. Epub 2017 Jun 15.

28.

AMPK negatively regulates tensin-dependent integrin activity.

Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, Yan Y, Sahgal P, Lerche M, Manneville JB, Mäkelä TP, Ivaska J.

J Cell Biol. 2017 Apr 3;216(4):1107-1121. doi: 10.1083/jcb.201609066. Epub 2017 Mar 13.

29.

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.

Lilja J, Zacharchenko T, Georgiadou M, Jacquemet G, De Franceschi N, Peuhu E, Hamidi H, Pouwels J, Martens V, Nia FH, Beifuss M, Boeckers T, Kreienkamp HJ, Barsukov IL, Ivaska J.

Nat Cell Biol. 2017 Apr;19(4):292-305. doi: 10.1038/ncb3487. Epub 2017 Mar 6.

30.

Vascular Morphogenesis: An Integrin and Fibronectin Highway.

Hamidi H, Ivaska J.

Curr Biol. 2017 Feb 20;27(4):R158-R161. doi: 10.1016/j.cub.2016.12.036.

31.

Erratum: Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.

De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J.

Nat Struct Mol Biol. 2017 Feb 6;24(2):194. doi: 10.1038/nsmb0217-194b. No abstract available.

PMID:
28169997
32.

SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attieh Y, Silva KA, Betz T, Sundberg JP, Salmi M, Deugnier MA, Eliceiri KW, Ivaska J.

EMBO J. 2017 Jan 17;36(2):165-182. doi: 10.15252/embj.201694387. Epub 2016 Dec 14.

33.

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling.

Jacquemet G, Baghirov H, Georgiadou M, Sihto H, Peuhu E, Cettour-Janet P, He T, Perälä M, Kronqvist P, Joensuu H, Ivaska J.

Nat Commun. 2016 Dec 2;7:13297. doi: 10.1038/ncomms13297.

34.

The complexity of integrins in cancer and new scopes for therapeutic targeting.

Hamidi H, Pietilä M, Ivaska J.

Br J Cancer. 2016 Oct 25;115(9):1017-1023. doi: 10.1038/bjc.2016.312. Epub 2016 Sep 29. Review.

35.

Fetal liver endothelium regulates the seeding of tissue-resident macrophages.

Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M.

Nature. 2016 Oct 20;538(7625):392-396. doi: 10.1038/nature19814. Epub 2016 Oct 12.

PMID:
27732581
36.

Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription.

Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventelä S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen PL, Joensuu H, Grenman R, Ivaska J.

Nat Commun. 2016 Aug 4;7:12237. doi: 10.1038/ncomms12237.

37.

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β-Slug signaling.

Cheng F, Shen Y, Mohanasundaram P, Lindström M, Ivaska J, Ny T, Eriksson JE.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4320-7. doi: 10.1073/pnas.1519197113. Epub 2016 Jul 8.

38.

Corrigendum: Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

Barrow-McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche BA, Noval AJ, Mai A, Guzmán C, Robbez-Masson L, Iturrioz X, Hulit J, Brennan CH, Hart IR, Parker PJ, Ivaska J, Kermorgant S.

Nat Commun. 2016 Jul 22;7:12392. doi: 10.1038/ncomms12392. No abstract available.

39.

Hospital Exemption for Advanced Therapy Medicinal Products: Issue in Application in the European Union Member States.

Ivaskiene T, Mauricas M, Ivaska J.

Curr Stem Cell Res Ther. 2017;12(1):45-51. Review.

PMID:
27412678
40.

Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

Barrow-McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche BA, Noval AJ, Mai A, Guzmán C, Robbez-Masson L, Iturrioz X, Hulit J, Brennan CH, Hart IR, Parker PJ, Ivaska J, Kermorgant S.

Nat Commun. 2016 Jun 23;7:11942. doi: 10.1038/ncomms11942. Erratum in: Nat Commun. 2016 Jul 22;7:12392. Robert-Masson, Luisa [corrected to Robbez, Masson].

41.

Eustachian Tube Opening Measurement by Sonotubometry Using Perfect Sequences for Healthy Adults.

Beleskiene V, Lesinskas E, Januskiene V, Daunoraviciene K, Rauba D, Ivaska J.

Clin Exp Otorhinolaryngol. 2016 Jun;9(2):116-22. doi: 10.21053/ceo.2015.00626. Epub 2016 Apr 19.

42.

Endosomes: Emerging Platforms for Integrin-Mediated FAK Signalling.

Alanko J, Ivaska J.

Trends Cell Biol. 2016 Jun;26(6):391-398. doi: 10.1016/j.tcb.2016.02.001. Epub 2016 Mar 2. Review.

PMID:
26944773
43.

Regulation of Cell Migration and β1 Integrin Trafficking by the Endosomal Adaptor GGA3.

Ratcliffe CD, Sahgal P, Parachoniak CA, Ivaska J, Park M.

Traffic. 2016 Jun;17(6):670-88. doi: 10.1111/tra.12390. Epub 2016 Apr 5.

44.

Integrin "endoadhesome" signaling suppresses anoikis.

Alanko J, Ivaska J.

Cell Cycle. 2016;15(5):605-6. doi: 10.1080/15384101.2015.1130576. Epub 2016 Feb 22. No abstract available.

45.

Whom to blame for metastasis, the epithelial-mesenchymal transition or the tumor microenvironment?

Pietilä M, Ivaska J, Mani SA.

Cancer Lett. 2016 Sep 28;380(1):359-68. doi: 10.1016/j.canlet.2015.12.033. Epub 2016 Jan 11. Review.

PMID:
26791236
46.

Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.

De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J.

Nat Struct Mol Biol. 2016 Feb;23(2):172-9. doi: 10.1038/nsmb.3161. Epub 2016 Jan 18. Erratum in: Nat Struct Mol Biol. 2017 Feb 6;24(2):194.

47.

Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling.

De Franceschi N, Peuhu E, Parsons M, Rissanen S, Vattulainen I, Salmi M, Ivaska J, Pouwels J.

PLoS One. 2015 Nov 23;10(11):e0143423. doi: 10.1371/journal.pone.0143423. eCollection 2015.

48.

Integrin endosomal signalling suppresses anoikis.

Alanko J, Mai A, Jacquemet G, Schauer K, Kaukonen R, Saari M, Goud B, Ivaska J.

Nat Cell Biol. 2015 Nov;17(11):1412-21. doi: 10.1038/ncb3250. Epub 2015 Oct 5.

49.

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα.

Wang Y, Arjonen A, Pouwels J, Ta H, Pausch P, Bange G, Engel U, Pan X, Fackler OT, Ivaska J, Grosse R.

Dev Cell. 2015 Aug 24;34(4):475-83. doi: 10.1016/j.devcel.2015.06.015. Epub 2015 Aug 6.

50.

Filopodia in cell adhesion, 3D migration and cancer cell invasion.

Jacquemet G, Hamidi H, Ivaska J.

Curr Opin Cell Biol. 2015 Oct;36:23-31. doi: 10.1016/j.ceb.2015.06.007. Epub 2015 Jul 14. Review. Erratum in: Curr Opin Cell Biol. 2015 Dec;37:119.

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