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Items: 1 to 50 of 95

1.

Structural, functional, and molecular impact on the cardiovascular system in ApoE-/- mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.

Szostak J, Titz B, Schlage WK, Guedj E, Sewer A, Phillips B, Leroy P, Buettner A, Neau L, Trivedi K, Martin F, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Chem Biol Interact. 2019 Nov 6:108887. doi: 10.1016/j.cbi.2019.108887. [Epub ahead of print]

PMID:
31705857
2.

Inhibition of Arabidopsis thaliana CIN-like TCP transcription factors by Agrobacterium T-DNA-encoded 6B proteins.

Potuschak T, Palatnik J, Schommer C, Sierro N, Ivanov NV, Kwon Y, Genschik P, Davière JM, Otten L.

Plant J. 2019 Oct 28. doi: 10.1111/tpj.14591. [Epub ahead of print]

PMID:
31659801
3.

Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.

Iskandar AR, Zanetti F, Marescotti D, Titz B, Sewer A, Kondylis A, Leroy P, Belcastro V, Torres LO, Acali S, Majeed S, Steiner S, Trivedi K, Guedj E, Merg C, Schneider T, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Arch Toxicol. 2019 Nov;93(11):3229-3247. doi: 10.1007/s00204-019-02565-9. Epub 2019 Sep 7.

PMID:
31494692
4.

3D human microvessel-on-a-chip model for studying monocyte-to-endothelium adhesion under flow - application in systems toxicology.

Poussin C, Kramer B, Lanz HL, Van den Heuvel A, Laurent A, Olivier T, Vermeer M, Peric D, Baumer K, Dulize R, Guedj E, Ivanov NV, Peitsch MC, Hoeng J, Joore J.

ALTEX. 2019 Aug 22. doi: 10.14573/altex.1811301. [Epub ahead of print]

5.

Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties.

Schorderet Weber S, Kaminski KP, Perret JL, Leroy P, Mazurov A, Peitsch MC, Ivanov NV, Hoeng J.

Food Chem Toxicol. 2019 Oct;132:110660. doi: 10.1016/j.fct.2019.110660. Epub 2019 Jul 3.

6.

A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2).

Martin F, Talikka M, Ivanov NV, Haziza C, Hoeng J, Peitsch MC.

Front Pharmacol. 2019 Mar 26;10:198. doi: 10.3389/fphar.2019.00198. eCollection 2019.

7.

GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology.

Belcastro V, Cano S, Marescotti D, Acali S, Poussin C, Gonzalez-Suarez I, Martin F, Bonjour F, Ivanov NV, Peitsch MC, Hoeng J.

Bioinformatics. 2019 Oct 15;35(20):4190-4192. doi: 10.1093/bioinformatics/btz187.

8.

Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.

Lee KM, Hoeng J, Harbo S, Kogel U, Gardner W, Oldham M, Benson E, Talikka M, Kondylis A, Martin F, Titz B, Ansari S, Trivedi K, Guedj E, Elamin A, Ivanov NV, Vanscheeuwijck P, Peitsch MC, McKinney WJ Jr.

Inhal Toxicol. 2018 Nov - Dec;30(13-14):553-567. doi: 10.1080/08958378.2019.1576807. Epub 2019 Mar 8.

PMID:
30849254
9.

A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.

Iskandar AR, Zanetti F, Kondylis A, Martin F, Leroy P, Majeed S, Steiner S, Xiang Y, Ortega Torres L, Trivedi K, Guedj E, Merg C, Frentzel S, Ivanov NV, Doshi U, Lee KM, McKinney WJ Jr, Peitsch MC, Hoeng J.

Intern Emerg Med. 2019 Sep;14(6):863-883. doi: 10.1007/s11739-019-02055-x. Epub 2019 Mar 5.

10.

A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.

Phillips B, Szostak J, Titz B, Schlage WK, Guedj E, Leroy P, Vuillaume G, Martin F, Buettner A, Elamin A, Sewer A, Sierro N, Choukrallah MA, Schneider T, Ivanov NV, Teng C, Tung CK, Lim WT, Yeo YS, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2019 Apr;126:113-141. doi: 10.1016/j.fct.2019.02.008. Epub 2019 Feb 12.

11.

How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.

Marescotti D, Serchi T, Luettich K, Xiang Y, Moschini E, Talikka M, Martin F, Baumer K, Dulize R, Peric D, Bornand D, Guedj E, Sewer A, Cambier S, Contal S, Chary A, Gutleb AC, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

ALTEX. 2019;36(3):388-402. doi: 10.14573/altex.1811221. Epub 2019 Feb 12.

12.

Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures.

Zanetti F, Sewer A, Titz B, Schlage WK, Iskandar AR, Kondylis A, Leroy P, Guedj E, Trivedi K, Elamin A, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2019 Mar;125:252-270. doi: 10.1016/j.fct.2018.12.056. Epub 2019 Jan 2.

13.

The impact of genome evolution on the allotetraploid Nicotiana rustica - an intriguing story of enhanced alkaloid production.

Sierro N, Battey JND, Bovet L, Liedschulte V, Ouadi S, Thomas J, Broye H, Laparra H, Vuarnoz A, Lang G, Goepfert S, Peitsch MC, Ivanov NV.

BMC Genomics. 2018 Nov 29;19(1):855. doi: 10.1186/s12864-018-5241-5.

14.

BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site.

Gordeeva J, Morozova N, Sierro N, Isaev A, Sinkunas T, Tsvetkova K, Matlashov M, Truncaite L, Morgan RD, Ivanov NV, Siksnys V, Zeng L, Severinov K.

Nucleic Acids Res. 2019 Jan 10;47(1):253-265. doi: 10.1093/nar/gky1125.

15.

Tobacco Heating System 2.2 has a limited impact on DNA methylation of candidate enhancers in mouse lung compared with cigarette smoke.

Choukrallah MA, Sierro N, Martin F, Baumer K, Thomas J, Ouadi S, Hoeng J, Peitsch MC, Ivanov NV.

Food Chem Toxicol. 2019 Jan;123:501-510. doi: 10.1016/j.fct.2018.11.020. Epub 2018 Nov 9.

16.

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.

Titz B, Gadaleta RM, Lo Sasso G, Elamin A, Ekroos K, Ivanov NV, Peitsch MC, Hoeng J.

Int J Mol Sci. 2018 Sep 15;19(9). pii: E2775. doi: 10.3390/ijms19092775. Review.

17.

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.

Iskandar AR, Martinez Y, Martin F, Schlage WK, Leroy P, Sewer A, Torres LO, Majeed S, Merg C, Trivedi K, Guedj E, Frentzel S, Mathis C, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Res (Camb). 2017 Sep 28;6(6):930-946. doi: 10.1039/c7tx00152e. eCollection 2017 Nov 1.

18.

In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells.

Poussin C, Laurent A, Kondylis A, Marescotti D, van der Toorn M, Guedj E, Goedertier D, Acali S, Pak C, Dulize R, Baumer K, Peric D, Maluenda E, Bornand D, Suarez IG, Schlage WK, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 Oct;120:390-406. doi: 10.1016/j.fct.2018.07.025. Epub 2018 Jul 17.

19.

Interrogating the microbiome: experimental and computational considerations in support of study reproducibility.

Poussin C, Sierro N, Boué S, Battey J, Scotti E, Belcastro V, Peitsch MC, Ivanov NV, Hoeng J.

Drug Discov Today. 2018 Sep;23(9):1644-1657. doi: 10.1016/j.drudis.2018.06.005. Epub 2018 Jun 8. Review.

20.

SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases.

Foerster H, Bombarely A, Battey JND, Sierro N, Ivanov NV, Mueller LA.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay035.

21.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.

Phillips BW, Schlage WK, Titz B, Kogel U, Sciuscio D, Martin F, Leroy P, Vuillaume G, Krishnan S, Lee T, Veljkovic E, Elamin A, Merg C, Ivanov NV, Peitsch MC, Hoeng J, Vanscheeuwijck P.

Food Chem Toxicol. 2018 Jun;116(Pt B):388-413. doi: 10.1016/j.fct.2018.04.015. Epub 2018 Apr 11.

22.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.

Titz B, Kogel U, Martin F, Schlage WK, Xiang Y, Nury C, Dijon S, Baumer K, Peric D, Bornand D, Dulize R, Phillips B, Leroy P, Vuillaume G, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:284-301. doi: 10.1016/j.fct.2018.02.058. Epub 2018 Mar 13.

23.

Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.

Zanetti F, Sewer A, Scotti E, Titz B, Schlage WK, Leroy P, Kondylis A, Vuillaume G, Iskandar AR, Guedj E, Trivedi K, Schneider T, Elamin A, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:148-169. doi: 10.1016/j.fct.2018.02.062. Epub 2018 Mar 2.

24.

Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.

Iskandar AR, Martin F, Leroy P, Schlage WK, Mathis C, Titz B, Kondylis A, Schneider T, Vuillaume G, Sewer A, Guedj E, Trivedi K, Elamin A, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:109-126. doi: 10.1016/j.fct.2018.02.063. Epub 2018 Mar 1.

25.

Organization of the TC and TE cellular T-DNA regions in Nicotiana otophora and functional analysis of three diverged TE-6b genes.

Chen K, Dorlhac de Borne F, Sierro N, Ivanov NV, Alouia M, Koechler S, Otten L.

Plant J. 2018 Apr;94(2):274-287. doi: 10.1111/tpj.13853. Epub 2018 Mar 23. Erratum in: Plant J. 2019 Aug;99(4):807.

26.

Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.

Phillips B, Titz B, Kogel U, Sharma D, Leroy P, Xiang Y, Vuillaume G, Lebrun S, Sciuscio D, Ho J, Nury C, Guedj E, Elamin A, Esposito M, Krishnan S, Schlage WK, Veljkovic E, Ivanov NV, Martin F, Peitsch MC, Hoeng J, Vanscheeuwijck P.

Food Chem Toxicol. 2017 Nov;109(Pt 1):315-332. doi: 10.1016/j.fct.2017.09.001. Epub 2017 Sep 5.

27.

Genomic Insights into the Evolution of the Nicotine Biosynthesis Pathway in Tobacco.

Kajikawa M, Sierro N, Kawaguchi H, Bakaher N, Ivanov NV, Hashimoto T, Shoji T.

Plant Physiol. 2017 Jun;174(2):999-1011. doi: 10.1104/pp.17.00070. Epub 2017 Apr 18.

28.

Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.

Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanetti F, Mathis C, Elamin A, Frentzel S, Schlage WK, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Res (Camb). 2017 May 29;6(5):631-653. doi: 10.1039/c7tx00047b. eCollection 2017 Sep 1.

29.

Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.

Szostak J, Boué S, Talikka M, Guedj E, Martin F, Phillips B, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2017 Mar;101:157-167. doi: 10.1016/j.fct.2017.01.013. Epub 2017 Jan 19.

30.

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.

Zanetti F, Titz B, Sewer A, Lo Sasso G, Scotti E, Schlage WK, Mathis C, Leroy P, Majeed S, Torres LO, Keppler BR, Elamin A, Trivedi K, Guedj E, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2017 Mar;101:15-35. doi: 10.1016/j.fct.2016.12.027. Epub 2016 Dec 23.

31.

Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.

Sewer A, Kogel U, Talikka M, Wong ET, Martin F, Xiang Y, Guedj E, Ivanov NV, Hoeng J, Peitsch MC.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S82-S92. doi: 10.1016/j.yrtph.2016.11.018. Epub 2016 Nov 17.

32.

A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.

Iskandar AR, Mathis C, Schlage WK, Frentzel S, Leroy P, Xiang Y, Sewer A, Majeed S, Ortega-Torres L, Johne S, Guedj E, Trivedi K, Kratzer G, Merg C, Elamin A, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol In Vitro. 2017 Mar;39:29-51. doi: 10.1016/j.tiv.2016.11.009. Epub 2016 Nov 16.

33.

Evaluation of the tobacco heating system 2.2. Part 9: Application of systems pharmacology to identify exposure response markers in peripheral blood of smokers switching to THS2.2.

Martin F, Talikka M, Ivanov NV, Haziza C, Hoeng J, Peitsch MC.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S151-S157. doi: 10.1016/j.yrtph.2016.11.011. Epub 2016 Nov 11.

34.

Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.

Oviedo A, Lebrun S, Kogel U, Ho J, Tan WT, Titz B, Leroy P, Vuillaume G, Bera M, Martin F, Rodrigo G, Esposito M, Dempsey R, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S93-S122. doi: 10.1016/j.yrtph.2016.11.004. Epub 2016 Nov 3.

35.

Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke.

Kogel U, Titz B, Schlage WK, Nury C, Martin F, Oviedo A, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S123-S138. doi: 10.1016/j.yrtph.2016.11.001. Epub 2016 Nov 4.

36.

Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.

Wong ET, Kogel U, Veljkovic E, Martin F, Xiang Y, Boue S, Vuillaume G, Leroy P, Guedj E, Rodrigo G, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S59-S81. doi: 10.1016/j.yrtph.2016.10.015. Epub 2016 Oct 26.

37.

Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.

Zanetti F, Sewer A, Mathis C, Iskandar AR, Kostadinova R, Schlage WK, Leroy P, Majeed S, Guedj E, Trivedi K, Martin F, Elamin A, Merg C, Ivanov NV, Frentzel S, Peitsch MC, Hoeng J.

Chem Res Toxicol. 2016 Aug 15;29(8):1252-69. doi: 10.1021/acs.chemrestox.6b00174. Epub 2016 Aug 5.

PMID:
27404394
38.

3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product.

Iskandar AR, Mathis C, Martin F, Leroy P, Sewer A, Majeed S, Kuehn D, Trivedi K, Grandolfo D, Cabanski M, Guedj E, Merg C, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

ALTEX. 2017;34(1):23-48. doi: 10.14573/altex.1605041. Epub 2016 Jul 7.

39.

Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice.

Elamin A, Titz B, Dijon S, Merg C, Geertz M, Schneider T, Martin F, Schlage WK, Frentzel S, Talamo F, Phillips B, Veljkovic E, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

J Proteomics. 2016 Aug 11;145:237-245. doi: 10.1016/j.jprot.2016.05.037. Epub 2016 Jun 5.

40.

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.

Phillips B, Veljkovic E, Boué S, Schlage WK, Vuillaume G, Martin F, Titz B, Leroy P, Buettner A, Elamin A, Oviedo A, Cabanski M, De León H, Guedj E, Schneider T, Talikka M, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Toxicol Sci. 2016 Jun;151(2):462-4. doi: 10.1093/toxsci/kfw062. No abstract available.

PMID:
27225756
41.

A framework for in vitro systems toxicology assessment of e-liquids.

Iskandar AR, Gonzalez-Suarez I, Majeed S, Marescotti D, Sewer A, Xiang Y, Leroy P, Guedj E, Mathis C, Schaller JP, Vanscheeuwijck P, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Mech Methods. 2016 Jul;26(6):389-413. doi: 10.3109/15376516.2016.1170251. Epub 2016 Apr 26.

42.

Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.

Lo Sasso G, Titz B, Nury C, Boué S, Phillips B, Belcastro V, Schneider T, Dijon S, Baumer K, Peric D, Dulize R, Elamin A, Guedj E, Buettner A, Leroy P, Kleinhans S, Vuillaume G, Veljkovic E, Ivanov NV, Martin F, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Inhal Toxicol. 2016 Apr;28(5):226-40. doi: 10.3109/08958378.2016.1150368. Epub 2016 Mar 30.

PMID:
27027324
43.

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.

Ansari S, Baumer K, Boué S, Dijon S, Dulize R, Ekroos K, Elamin A, Foong C, Guedj E, Hoeng J, Ivanov NV, Krishnan S, Leroy P, Martin F, Merg C, Peck MJ, Peitsch MC, Phillips B, Schlage WK, Schneider T, Talikka M, Titz B, Vanscheeuwijck P, Veljkovic E, Vihervaara T, Vuillaume G, Woon CQ.

Sci Data. 2016 Jan 5;3:150077. doi: 10.1038/sdata.2015.77.

44.

In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.

Gonzalez-Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov NV, Mathis C, Hoeng J, Peitsch MC.

Chem Res Toxicol. 2016 Jan 19;29(1):3-18. doi: 10.1021/acs.chemrestox.5b00321. Epub 2015 Dec 29.

PMID:
26651182
45.

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.

Phillips B, Veljkovic E, Boué S, Schlage WK, Vuillaume G, Martin F, Titz B, Leroy P, Buettner A, Elamin A, Oviedo A, Cabanski M, De León H, Guedj E, Schneider T, Talikka M, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Toxicol Sci. 2016 Feb;149(2):411-32. doi: 10.1093/toxsci/kfv243. Epub 2015 Nov 25. Erratum in: Toxicol Sci. 2016 Jun;151(2):462-4.

46.

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.

Titz B, Boué S, Phillips B, Talikka M, Vihervaara T, Schneider T, Nury C, Elamin A, Guedj E, Peck MJ, Schlage WK, Cabanski M, Leroy P, Vuillaume G, Martin F, Ivanov NV, Veljkovic E, Ekroos K, Laaksonen R, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Toxicol Sci. 2016 Feb;149(2):441-57. doi: 10.1093/toxsci/kfv244. Epub 2015 Nov 17.

47.

Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects.

Titz B, Sewer A, Schneider T, Elamin A, Martin F, Dijon S, Luettich K, Guedj E, Vuillaume G, Ivanov NV, Peck MJ, Chaudhary NI, Hoeng J, Peitsch MC.

J Proteomics. 2015 Oct 14;128:306-20. doi: 10.1016/j.jprot.2015.08.009. Epub 2015 Aug 22.

48.

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.

Iskandar AR, Xiang Y, Frentzel S, Talikka M, Leroy P, Kuehn D, Guedj E, Martin F, Mathis C, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16.

49.

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.

Cabanski M, Fields B, Boue S, Boukharov N, DeLeon H, Dror N, Geertz M, Guedj E, Iskandar A, Kogel U, Merg C, Peck MJ, Poussin C, Schlage WK, Talikka M, Ivanov NV, Hoeng J, Peitsch MC.

Inflamm Res. 2015 Jul;64(7):471-86. doi: 10.1007/s00011-015-0820-2. Epub 2015 May 12.

50.

A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.

Phillips B, Veljkovic E, Peck MJ, Buettner A, Elamin A, Guedj E, Vuillaume G, Ivanov NV, Martin F, Boué S, Schlage WK, Schneider T, Titz B, Talikka M, Vanscheeuwijck P, Hoeng J, Peitsch MC.

Food Chem Toxicol. 2015 Jun;80:328-345. doi: 10.1016/j.fct.2015.03.009. Epub 2015 Apr 2.

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