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Items: 1 to 50 of 414

1.

Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation.

Price AJ, Collado-Torres L, Ivanov NA, Xia W, Burke EE, Shin JH, Tao R, Ma L, Jia Y, Hyde TM, Kleinman JE, Weinberger DR, Jaffe AE.

Genome Biol. 2019 Sep 26;20(1):196. doi: 10.1186/s13059-019-1805-1.

2.

Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion.

Witkoff BM, Ivanov NN, Trotter SC.

Case Rep Dermatol. 2019 Aug 6;11(2):233-238. doi: 10.1159/000501875. eCollection 2019 May-Aug.

3.

Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.

Iskandar AR, Zanetti F, Marescotti D, Titz B, Sewer A, Kondylis A, Leroy P, Belcastro V, Torres LO, Acali S, Majeed S, Steiner S, Trivedi K, Guedj E, Merg C, Schneider T, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Arch Toxicol. 2019 Sep 7. doi: 10.1007/s00204-019-02565-9. [Epub ahead of print]

PMID:
31494692
4.

3D human microvessel-on-a-chip model for studying monocyte-to-endothelium adhesion under flow - application in systems toxicology.

Poussin C, Kramer B, Lanz HL, Van den Heuvel A, Laurent A, Olivier T, Vermeer M, Peric D, Baumer K, Dulize R, Guedj E, Ivanov NV, Peitsch MC, Hoeng J, Joore J.

ALTEX. 2019 Aug 22. doi: 10.14573/altex.1811301. [Epub ahead of print]

5.

Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties.

Schorderet Weber S, Kaminski KP, Perret JL, Leroy P, Mazurov A, Peitsch MC, Ivanov NV, Hoeng J.

Food Chem Toxicol. 2019 Oct;132:110660. doi: 10.1016/j.fct.2019.110660. Epub 2019 Jul 3.

6.

Non-aqueous continuous-flow electrophoresis (NACFE): potential separation complement for continuous-flow organic synthesis.

Ivanov NA, Liu Y, Kochmann S, Krylov SN.

Lab Chip. 2019 Jun 25;19(13):2156-2160. doi: 10.1039/c9lc00460b.

PMID:
31161184
7.

Economic and health burden of brucellosis in Kazakhstan.

Charypkhan D, Sultanov AA, Ivanov NP, Baramova SA, Taitubayev MK, Torgerson PR.

Zoonoses Public Health. 2019 Aug;66(5):487-494. doi: 10.1111/zph.12582. Epub 2019 May 14.

PMID:
31090193
8.

Highly sensitive detection of influenza virus with SERS aptasensor.

Kukushkin VI, Ivanov NM, Novoseltseva AA, Gambaryan AS, Yaminsky IV, Kopylov AM, Zavyalova EG.

PLoS One. 2019 Apr 25;14(4):e0216247. doi: 10.1371/journal.pone.0216247. eCollection 2019.

9.

Merkel cell carcinoma: an aggressive cutaneous carcinoma with rare metastasis to the thyroid gland.

Vaiciunaite D, Beddell G, Ivanov N.

BMJ Case Rep. 2019 Apr 23;12(4). pii: e228273. doi: 10.1136/bcr-2018-228273.

PMID:
31015241
10.

A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2).

Martin F, Talikka M, Ivanov NV, Haziza C, Hoeng J, Peitsch MC.

Front Pharmacol. 2019 Mar 26;10:198. doi: 10.3389/fphar.2019.00198. eCollection 2019.

11.

GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology.

Belcastro V, Cano S, Marescotti D, Acali S, Poussin C, Gonzalez-Suarez I, Martin F, Bonjour F, Ivanov NV, Peitsch MC, Hoeng J.

Bioinformatics. 2019 Oct 15;35(20):4190-4192. doi: 10.1093/bioinformatics/btz187.

12.

Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.

Lee KM, Hoeng J, Harbo S, Kogel U, Gardner W, Oldham M, Benson E, Talikka M, Kondylis A, Martin F, Titz B, Ansari S, Trivedi K, Guedj E, Elamin A, Ivanov NV, Vanscheeuwijck P, Peitsch MC, McKinney WJ Jr.

Inhal Toxicol. 2018 Nov - Dec;30(13-14):553-567. doi: 10.1080/08958378.2019.1576807. Epub 2019 Mar 8.

PMID:
30849254
13.

A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.

Iskandar AR, Zanetti F, Kondylis A, Martin F, Leroy P, Majeed S, Steiner S, Xiang Y, Ortega Torres L, Trivedi K, Guedj E, Merg C, Frentzel S, Ivanov NV, Doshi U, Lee KM, McKinney WJ Jr, Peitsch MC, Hoeng J.

Intern Emerg Med. 2019 Sep;14(6):863-883. doi: 10.1007/s11739-019-02055-x. Epub 2019 Mar 5.

14.

A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.

Phillips B, Szostak J, Titz B, Schlage WK, Guedj E, Leroy P, Vuillaume G, Martin F, Buettner A, Elamin A, Sewer A, Sierro N, Choukrallah MA, Schneider T, Ivanov NV, Teng C, Tung CK, Lim WT, Yeo YS, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2019 Apr;126:113-141. doi: 10.1016/j.fct.2019.02.008. Epub 2019 Feb 12.

15.

How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.

Marescotti D, Serchi T, Luettich K, Xiang Y, Moschini E, Talikka M, Martin F, Baumer K, Dulize R, Peric D, Bornand D, Guedj E, Sewer A, Cambier S, Contal S, Chary A, Gutleb AC, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

ALTEX. 2019;36(3):388-402. doi: 10.14573/altex.1811221. Epub 2019 Feb 12.

16.

Corrigendum to "The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product" published in Toxicology in Vitro, Volume 50, August 2018, Pages 95-108.

van der Toorn M, Sewer A, Marescotti D, Johne S, Baumer K, Bornand D, Dulize R, Merg C, Corciulo M, Scotti E, Pak C, Leroy P, Guedj E, Ivanov N, Martin F, Peitsch M, Hoeng J, Luettich K.

Toxicol In Vitro. 2019 Apr;56:194-195. doi: 10.1016/j.tiv.2019.01.011. Epub 2019 Jan 25. No abstract available.

17.

Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation.

Chen Y, Fachko D, Ivanov NS, Skinner CM, Skalsky RL.

PLoS Pathog. 2019 Jan 7;15(1):e1007535. doi: 10.1371/journal.ppat.1007535. eCollection 2019 Jan.

18.

Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures.

Zanetti F, Sewer A, Titz B, Schlage WK, Iskandar AR, Kondylis A, Leroy P, Guedj E, Trivedi K, Elamin A, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2019 Mar;125:252-270. doi: 10.1016/j.fct.2018.12.056. Epub 2019 Jan 2.

19.

Health-related Quality of Life for Abiraterone Plus Prednisone Versus Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer: Results from a Phase II Randomized Trial.

Khalaf DJ, Sunderland K, Eigl BJ, Kollmannsberger CK, Ivanov N, Finch DL, Oja C, Vergidis J, Zulfiqar M, Gleave ME, Chi KN.

Eur Urol. 2019 Jun;75(6):940-947. doi: 10.1016/j.eururo.2018.12.015. Epub 2018 Dec 24.

PMID:
30591354
20.

The impact of genome evolution on the allotetraploid Nicotiana rustica - an intriguing story of enhanced alkaloid production.

Sierro N, Battey JND, Bovet L, Liedschulte V, Ouadi S, Thomas J, Broye H, Laparra H, Vuarnoz A, Lang G, Goepfert S, Peitsch MC, Ivanov NV.

BMC Genomics. 2018 Nov 29;19(1):855. doi: 10.1186/s12864-018-5241-5.

21.

BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site.

Gordeeva J, Morozova N, Sierro N, Isaev A, Sinkunas T, Tsvetkova K, Matlashov M, Truncaite L, Morgan RD, Ivanov NV, Siksnys V, Zeng L, Severinov K.

Nucleic Acids Res. 2019 Jan 10;47(1):253-265. doi: 10.1093/nar/gky1125.

22.

Tobacco Heating System 2.2 has a limited impact on DNA methylation of candidate enhancers in mouse lung compared with cigarette smoke.

Choukrallah MA, Sierro N, Martin F, Baumer K, Thomas J, Ouadi S, Hoeng J, Peitsch MC, Ivanov NV.

Food Chem Toxicol. 2019 Jan;123:501-510. doi: 10.1016/j.fct.2018.11.020. Epub 2018 Nov 9.

23.

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.

Titz B, Gadaleta RM, Lo Sasso G, Elamin A, Ekroos K, Ivanov NV, Peitsch MC, Hoeng J.

Int J Mol Sci. 2018 Sep 15;19(9). pii: E2775. doi: 10.3390/ijms19092775. Review.

24.

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.

Iskandar AR, Martinez Y, Martin F, Schlage WK, Leroy P, Sewer A, Torres LO, Majeed S, Merg C, Trivedi K, Guedj E, Frentzel S, Mathis C, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Res (Camb). 2017 Sep 28;6(6):930-946. doi: 10.1039/c7tx00152e. eCollection 2017 Nov 1.

25.

In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells.

Poussin C, Laurent A, Kondylis A, Marescotti D, van der Toorn M, Guedj E, Goedertier D, Acali S, Pak C, Dulize R, Baumer K, Peric D, Maluenda E, Bornand D, Suarez IG, Schlage WK, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 Oct;120:390-406. doi: 10.1016/j.fct.2018.07.025. Epub 2018 Jul 17.

26.

Interrogating the microbiome: experimental and computational considerations in support of study reproducibility.

Poussin C, Sierro N, Boué S, Battey J, Scotti E, Belcastro V, Peitsch MC, Ivanov NV, Hoeng J.

Drug Discov Today. 2018 Sep;23(9):1644-1657. doi: 10.1016/j.drudis.2018.06.005. Epub 2018 Jun 8. Review.

27.

Medical Students' Knowledge, Attitudes, and Behaviors With Regard to Skin Cancer and Sun-Protective Behaviors.

Ivanov NN, Swan A, Guseman EH, Whipps J, Jensen LL, Beverly EA.

J Am Osteopath Assoc. 2018 Jul 1;118(7):444-454. doi: 10.7556/jaoa.2018.098.

PMID:
29889933
28.

SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases.

Foerster H, Bombarely A, Battey JND, Sierro N, Ivanov NV, Mueller LA.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay035.

29.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.

Phillips BW, Schlage WK, Titz B, Kogel U, Sciuscio D, Martin F, Leroy P, Vuillaume G, Krishnan S, Lee T, Veljkovic E, Elamin A, Merg C, Ivanov NV, Peitsch MC, Hoeng J, Vanscheeuwijck P.

Food Chem Toxicol. 2018 Jun;116(Pt B):388-413. doi: 10.1016/j.fct.2018.04.015. Epub 2018 Apr 11.

30.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.

Titz B, Kogel U, Martin F, Schlage WK, Xiang Y, Nury C, Dijon S, Baumer K, Peric D, Bornand D, Dulize R, Phillips B, Leroy P, Vuillaume G, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:284-301. doi: 10.1016/j.fct.2018.02.058. Epub 2018 Mar 13.

31.

The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.

van der Toorn M, Sewer A, Marescotti D, Johne S, Baumer K, Bornand D, Dulize R, Merg C, Corciulo M, Scotti E, Pak C, Leroy P, Guedj E, Ivanov N, Martin F, Peitsch M, Hoeng J, Luettich K.

Toxicol In Vitro. 2018 Aug;50:95-108. doi: 10.1016/j.tiv.2018.02.019. Epub 2018 Mar 7. Erratum in: Toxicol In Vitro. 2019 Apr;56:194-195.

32.

Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.

Zanetti F, Sewer A, Scotti E, Titz B, Schlage WK, Leroy P, Kondylis A, Vuillaume G, Iskandar AR, Guedj E, Trivedi K, Schneider T, Elamin A, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:148-169. doi: 10.1016/j.fct.2018.02.062. Epub 2018 Mar 2.

33.

Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.

Iskandar AR, Martin F, Leroy P, Schlage WK, Mathis C, Titz B, Kondylis A, Schneider T, Vuillaume G, Sewer A, Guedj E, Trivedi K, Elamin A, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2018 May;115:109-126. doi: 10.1016/j.fct.2018.02.063. Epub 2018 Mar 1.

34.

Organization of the TC and TE cellular T-DNA regions in Nicotiana otophora and functional analysis of three diverged TE-6b genes.

Chen K, Dorlhac de Borne F, Sierro N, Ivanov NV, Alouia M, Koechler S, Otten L.

Plant J. 2018 Apr;94(2):274-287. doi: 10.1111/tpj.13853. Epub 2018 Mar 23. Erratum in: Plant J. 2019 Aug;99(4):807.

35.

Direct visualization of the oligomeric state of hemagglutinins of influenza virus by high-resolution atomic force microscopy.

Barinov N, Ivanov N, Kopylov A, Klinov D, Zavyalova E.

Biochimie. 2018 Mar;146:148-155. doi: 10.1016/j.biochi.2017.12.014. Epub 2018 Jan 2.

PMID:
29305173
36.

A Content Analysis of Testosterone Websites: Sex, Muscle, and Male Age-Related Thematic Differences.

Ivanov N, Vuong J, Gray PB.

Am J Mens Health. 2018 Mar;12(2):388-397. doi: 10.1177/1557988317734667. Epub 2017 Oct 13.

37.

Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.

Phillips B, Titz B, Kogel U, Sharma D, Leroy P, Xiang Y, Vuillaume G, Lebrun S, Sciuscio D, Ho J, Nury C, Guedj E, Elamin A, Esposito M, Krishnan S, Schlage WK, Veljkovic E, Ivanov NV, Martin F, Peitsch MC, Hoeng J, Vanscheeuwijck P.

Food Chem Toxicol. 2017 Nov;109(Pt 1):315-332. doi: 10.1016/j.fct.2017.09.001. Epub 2017 Sep 5.

38.

An Epstein-Barr Virus MicroRNA Blocks Interleukin-1 (IL-1) Signaling by Targeting IL-1 Receptor 1.

Skinner CM, Ivanov NS, Barr SA, Chen Y, Skalsky RL.

J Virol. 2017 Oct 13;91(21). pii: e00530-17. doi: 10.1128/JVI.00530-17. Print 2017 Nov 1.

39.

Nanodiamond-chymotrypsin and nanodiamond-papain conjugates, their synthesis and activity and visualization of their interaction with cells using optical and electron microscopy.

Golyshev SA, Berkovich AK, Yakovlev RY, Bystrov DM, Ivanov NM, Balandina GN, Rudenskaya GN.

Biointerphases. 2017 Jul 28;12(3):031004. doi: 10.1116/1.4996108.

PMID:
28754039
40.

Genomic Insights into the Evolution of the Nicotine Biosynthesis Pathway in Tobacco.

Kajikawa M, Sierro N, Kawaguchi H, Bakaher N, Ivanov NV, Hashimoto T, Shoji T.

Plant Physiol. 2017 Jun;174(2):999-1011. doi: 10.1104/pp.17.00070. Epub 2017 Apr 18.

41.

Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.

Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanetti F, Mathis C, Elamin A, Frentzel S, Schlage WK, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol Res (Camb). 2017 May 29;6(5):631-653. doi: 10.1039/c7tx00047b. eCollection 2017 Sep 1.

42.

Integrate imaging approach for minimally invasive and robotic procedures.

Ivanov NA, Green DB, Guy TS.

J Thorac Dis. 2017 Apr;9(Suppl 4):S264-S270. doi: 10.21037/jtd.2017.03.141. Review.

43.

Is diabetes distress on your radar screen?

Beverly EA, Ivanov NN, Court AB, Fredricks TR.

J Fam Pract. 2017 Jan;66(1):9-14. Review.

PMID:
28188312
44.

Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.

Szostak J, Boué S, Talikka M, Guedj E, Martin F, Phillips B, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2017 Mar;101:157-167. doi: 10.1016/j.fct.2017.01.013. Epub 2017 Jan 19.

45.

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.

Zanetti F, Titz B, Sewer A, Lo Sasso G, Scotti E, Schlage WK, Mathis C, Leroy P, Majeed S, Torres LO, Keppler BR, Elamin A, Trivedi K, Guedj E, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J.

Food Chem Toxicol. 2017 Mar;101:15-35. doi: 10.1016/j.fct.2016.12.027. Epub 2016 Dec 23.

46.

Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.

Sewer A, Kogel U, Talikka M, Wong ET, Martin F, Xiang Y, Guedj E, Ivanov NV, Hoeng J, Peitsch MC.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S82-S92. doi: 10.1016/j.yrtph.2016.11.018. Epub 2016 Nov 17.

47.

A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.

Iskandar AR, Mathis C, Schlage WK, Frentzel S, Leroy P, Xiang Y, Sewer A, Majeed S, Ortega-Torres L, Johne S, Guedj E, Trivedi K, Kratzer G, Merg C, Elamin A, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Toxicol In Vitro. 2017 Mar;39:29-51. doi: 10.1016/j.tiv.2016.11.009. Epub 2016 Nov 16.

48.

Evaluation of the tobacco heating system 2.2. Part 9: Application of systems pharmacology to identify exposure response markers in peripheral blood of smokers switching to THS2.2.

Martin F, Talikka M, Ivanov NV, Haziza C, Hoeng J, Peitsch MC.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S151-S157. doi: 10.1016/j.yrtph.2016.11.011. Epub 2016 Nov 11.

49.

Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.

Oviedo A, Lebrun S, Kogel U, Ho J, Tan WT, Titz B, Leroy P, Vuillaume G, Bera M, Martin F, Rodrigo G, Esposito M, Dempsey R, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S93-S122. doi: 10.1016/j.yrtph.2016.11.004. Epub 2016 Nov 3.

50.

Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke.

Kogel U, Titz B, Schlage WK, Nury C, Martin F, Oviedo A, Lebrun S, Elamin A, Guedj E, Trivedi K, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S123-S138. doi: 10.1016/j.yrtph.2016.11.001. Epub 2016 Nov 4.

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