Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66

1.

Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells.

Bornstein C, Nevo S, Giladi A, Kadouri N, Pouzolles M, Gerbe F, David E, Machado A, Chuprin A, Tóth B, Goldberg O, Itzkovitz S, Taylor N, Jay P, Zimmermann VS, Abramson J, Amit I.

Nature. 2018 Jul 18. doi: 10.1038/s41586-018-0346-1. [Epub ahead of print]

PMID:
30022162
2.

Design principles of the paradoxical feedback between pancreatic alpha and beta cells.

Garzilli I, Itzkovitz S.

Sci Rep. 2018 Jul 16;8(1):10694. doi: 10.1038/s41598-018-29084-4.

3.

Pax6 regulation of Sox9 in the retinal pigmented epithelium controls its timely differentiation and choroid vasculature development.

Cohen-Tayar Y, Cohen H, Mitiagin Y, Abarbanel Z, Levy C, Idelson M, Reubinoff B, Itzkovitz S, Raviv S, Kaestner K, Blinder P, Elkon R, Ashery-Padan R.

Development. 2018 Jul 9. pii: dev.163691. doi: 10.1242/dev.163691. [Epub ahead of print]

PMID:
29986868
4.

Author Correction: Subepithelial telocytes are an important source of Wnts that supports intestinal crypts.

Shoshkes-Carmel M, Wang YJ, Wangensteen KJ, Tóth B, Kondo A, Massasa EE, Itzkovitz S, Kaestner KH.

Nature. 2018 Jul 5. doi: 10.1038/s41586-018-0286-9. [Epub ahead of print]

PMID:
29977061
5.

Subepithelial telocytes are an important source of Wnts that supports intestinal crypts.

Shoshkes-Carmel M, Wang YJ, Wangensteen KJ, Tóth B, Kondo A, Massasa EE, Itzkovitz S, Kaestner KH.

Nature. 2018 May;557(7704):242-246. doi: 10.1038/s41586-018-0084-4. Epub 2018 May 2. Erratum in: Nature. 2018 Jul 5;:.

PMID:
29720649
6.

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

Morgenstern Y, Das Adhikari U, Ayyash M, Elyada E, Tóth B, Moor A, Itzkovitz S, Ben-Neriah Y.

EMBO J. 2017 Oct 16;36(20):3046-3061. doi: 10.15252/embj.201696253. Epub 2017 Sep 28.

PMID:
28963394
7.

Global mRNA polarization regulates translation efficiency in the intestinal epithelium.

Moor AE, Golan M, Massasa EE, Lemze D, Weizman T, Shenhav R, Baydatch S, Mizrahi O, Winkler R, Golani O, Stern-Ginossar N, Itzkovitz S.

Science. 2017 Sep 22;357(6357):1299-1303. doi: 10.1126/science.aan2399. Epub 2017 Aug 10.

8.

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.

Keren-Shaul H, Spinrad A, Weiner A, Matcovitch-Natan O, Dvir-Szternfeld R, Ulland TK, David E, Baruch K, Lara-Astaiso D, Toth B, Itzkovitz S, Colonna M, Schwartz M, Amit I.

Cell. 2017 Jun 15;169(7):1276-1290.e17. doi: 10.1016/j.cell.2017.05.018. Epub 2017 Jun 8.

9.

Spatial transcriptomics: paving the way for tissue-level systems biology.

Moor AE, Itzkovitz S.

Curr Opin Biotechnol. 2017 Aug;46:126-133. doi: 10.1016/j.copbio.2017.02.004. Epub 2017 Mar 24. Review.

PMID:
28346891
10.

Erratum: Single-cell spatial reconstruction reveals global division of labour in the mammalian liver.

Halpern KB, Shenhav R, Matcovitch-Natan O, Tóth B, Lemze D, Golan M, Massasa EE, Baydatch S, Landen S, Moor AE, Brandis A, Giladi A, Stokar-Avihail A, David E, Amit I, Itzkovitz S.

Nature. 2017 Mar 30;543(7647):742. doi: 10.1038/nature21729. Epub 2017 Mar 15. No abstract available.

PMID:
28297709
11.

Single-cell spatial reconstruction reveals global division of labour in the mammalian liver.

Halpern KB, Shenhav R, Matcovitch-Natan O, Toth B, Lemze D, Golan M, Massasa EE, Baydatch S, Landen S, Moor AE, Brandis A, Giladi A, Avihail AS, David E, Amit I, Itzkovitz S.

Nature. 2017 Feb 16;542(7641):352-356. doi: 10.1038/nature21065. Epub 2017 Feb 6. Erratum in: Nature. 2017 Mar 30;543(7647):742.

12.

Early commitment and robust differentiation in colonic crypts.

Tóth B, Ben-Moshe S, Gavish A, Barkai N, Itzkovitz S.

Mol Syst Biol. 2017 Jan 3;13(1):902. doi: 10.15252/msb.20167283.

13.

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

Gury-BenAri M, Thaiss CA, Serafini N, Winter DR, Giladi A, Lara-Astiaso D, Levy M, Salame TM, Weiner A, David E, Shapiro H, Dori-Bachash M, Pevsner-Fischer M, Lorenzo-Vivas E, Keren-Shaul H, Paul F, Harmelin A, Eberl G, Itzkovitz S, Tanay A, Di Santo JP, Elinav E, Amit I.

Cell. 2016 Aug 25;166(5):1231-1246.e13. doi: 10.1016/j.cell.2016.07.043. Epub 2016 Aug 18.

14.

A systematic view on influenza induced host shutoff.

Bercovich-Kinori A, Tai J, Gelbart IA, Shitrit A, Ben-Moshe S, Drori Y, Itzkovitz S, Mandelboim M, Stern-Ginossar N.

Elife. 2016 Aug 15;5. pii: e18311. doi: 10.7554/eLife.18311.

15.

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells.

Tichon A, Gil N, Lubelsky Y, Havkin Solomon T, Lemze D, Itzkovitz S, Stern-Ginossar N, Ulitsky I.

Nat Commun. 2016 Jul 13;7:12209. doi: 10.1038/ncomms12209.

16.

Microglia development follows a stepwise program to regulate brain homeostasis.

Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I.

Science. 2016 Aug 19;353(6301):aad8670. doi: 10.1126/science.aad8670. Epub 2016 Jun 23.

17.

Dynamic zonation of liver polyploidy.

Tanami S, Ben-Moshe S, Elkayam A, Mayo A, Bahar Halpern K, Itzkovitz S.

Cell Tissue Res. 2017 May;368(2):405-410. doi: 10.1007/s00441-016-2427-5. Epub 2016 Jun 15.

PMID:
27301446
18.

The Genetic Program of Pancreatic β-Cell Replication In Vivo.

Klochendler A, Caspi I, Corem N, Moran M, Friedlich O, Elgavish S, Nevo Y, Helman A, Glaser B, Eden A, Itzkovitz S, Dor Y.

Diabetes. 2016 Jul;65(7):2081-93. doi: 10.2337/db16-0003. Epub 2016 Mar 18.

19.

Bursting through the cell cycle.

Ben-Moshe S, Itzkovitz S.

Elife. 2016 Mar 7;5:e14953. doi: 10.7554/eLife.14953.

20.

Nuclear Retention of mRNA in Mammalian Tissues.

Bahar Halpern K, Caspi I, Lemze D, Levy M, Landen S, Elinav E, Ulitsky I, Itzkovitz S.

Cell Rep. 2015 Dec 29;13(12):2653-62. doi: 10.1016/j.celrep.2015.11.036. Epub 2015 Dec 17.

21.

Single molecule approaches for quantifying transcription and degradation rates in intact mammalian tissues.

Bahar Halpern K, Itzkovitz S.

Methods. 2016 Apr 1;98:134-142. doi: 10.1016/j.ymeth.2015.11.015. Epub 2015 Nov 29.

PMID:
26611432
22.

Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, Korman S, Itzkovitz S, Dimmock D, Ulitsky I, Nagamani SC, Ruppin E, Erez A.

Nature. 2015 Nov 19;527(7578):379-383. doi: 10.1038/nature15529. Epub 2015 Nov 11.

23.

Aging, clonal hematopoiesis and preleukemia: not just bad luck?

Shlush LI, Zandi S, Itzkovitz S, Schuh AC.

Int J Hematol. 2015 Nov;102(5):513-22. doi: 10.1007/s12185-015-1870-5. Epub 2015 Oct 6. Review.

PMID:
26440972
24.

Bursty gene expression in the intact mammalian liver.

Bahar Halpern K, Tanami S, Landen S, Chapal M, Szlak L, Hutzler A, Nizhberg A, Itzkovitz S.

Mol Cell. 2015 Apr 2;58(1):147-56. doi: 10.1016/j.molcel.2015.01.027. Epub 2015 Feb 26.

25.

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.

Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K.

Cell Rep. 2014 Feb 13;6(3):514-27. doi: 10.1016/j.celrep.2013.12.041. Epub 2014 Jan 23.

26.

Genetic and phenotypic diversity in breast tumor metastases.

Almendro V, Kim HJ, Cheng YK, Gönen M, Itzkovitz S, Argani P, van Oudenaarden A, Sukumar S, Michor F, Polyak K.

Cancer Res. 2014 Mar 1;74(5):1338-48. doi: 10.1158/0008-5472.CAN-13-2357-T. Epub 2014 Jan 21.

27.

Single-molecule mRNA detection and counting in mammalian tissue.

Lyubimova A, Itzkovitz S, Junker JP, Fan ZP, Wu X, van Oudenaarden A.

Nat Protoc. 2013 Sep;8(9):1743-58. doi: 10.1038/nprot.2013.109. Epub 2013 Aug 15.

PMID:
23949380
28.

A versatile genome-scale PCR-based pipeline for high-definition DNA FISH.

Bienko M, Crosetto N, Teytelman L, Klemm S, Itzkovitz S, van Oudenaarden A.

Nat Methods. 2013 Feb;10(2):122-124. doi: 10.1038/nmeth.2306. Epub 2012 Dec 23.

29.

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

Muñoz J, Stange DE, Schepers AG, van de Wetering M, Koo BK, Itzkovitz S, Volckmann R, Kung KS, Koster J, Radulescu S, Myant K, Versteeg R, Sansom OJ, van Es JH, Barker N, van Oudenaarden A, Mohammed S, Heck AJ, Clevers H.

EMBO J. 2012 Jun 12;31(14):3079-91. doi: 10.1038/emboj.2012.166.

30.

Functional consequences of necdin nucleocytoplasmic localization.

Lavi-Itzkovitz A, Tcherpakov M, Levy Z, Itzkovitz S, Muscatelli F, Fainzilber M.

PLoS One. 2012;7(3):e33786. doi: 10.1371/journal.pone.0033786. Epub 2012 Mar 19.

31.

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.

van Es JH, Haegebarth A, Kujala P, Itzkovitz S, Koo BK, Boj SF, Korving J, van den Born M, van Oudenaarden A, Robine S, Clevers H.

Mol Cell Biol. 2012 May;32(10):1918-27. doi: 10.1128/MCB.06288-11. Epub 2012 Mar 5.

32.

Slug and Sox9 cooperatively determine the mammary stem cell state.

Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA.

Cell. 2012 Mar 2;148(5):1015-28. doi: 10.1016/j.cell.2012.02.008.

33.

Cell lineage analysis of the mammalian female germline.

Reizel Y, Itzkovitz S, Adar R, Elbaz J, Jinich A, Chapal-Ilani N, Maruvka YE, Nevo N, Marx Z, Horovitz I, Wasserstrom A, Mayo A, Shur I, Benayahu D, Skorecki K, Segal E, Dekel N, Shapiro E.

PLoS Genet. 2012;8(2):e1002477. doi: 10.1371/journal.pgen.1002477. Epub 2012 Feb 23.

34.

Optimality in the development of intestinal crypts.

Itzkovitz S, Blat IC, Jacks T, Clevers H, van Oudenaarden A.

Cell. 2012 Feb 3;148(3):608-19. doi: 10.1016/j.cell.2011.12.025.

35.

Single-molecule transcript counting of stem-cell markers in the mouse intestine.

Itzkovitz S, Lyubimova A, Blat IC, Maynard M, van Es J, Lees J, Jacks T, Clevers H, van Oudenaarden A.

Nat Cell Biol. 2011 Nov 27;14(1):106-14. doi: 10.1038/ncb2384.

36.

Muscle-bound primordial stem cells give rise to myofiber-associated myogenic and non-myogenic progenitors.

Segev E, Shefer G, Adar R, Chapal-Ilani N, Itzkovitz S, Horovitz I, Reizel Y, Benayahu D, Shapiro E.

PLoS One. 2011;6(10):e25605. doi: 10.1371/journal.pone.0025605. Epub 2011 Oct 14.

37.

Colon stem cell and crypt dynamics exposed by cell lineage reconstruction.

Reizel Y, Chapal-Ilani N, Adar R, Itzkovitz S, Elbaz J, Maruvka YE, Segev E, Shlush LI, Dekel N, Shapiro E.

PLoS Genet. 2011 Jul;7(7):e1002192. doi: 10.1371/journal.pgen.1002192. Epub 2011 Jul 28.

38.

Quantitative digital in situ senescence-associated β-galactosidase assay.

Shlush LI, Itzkovitz S, Cohen A, Rutenberg A, Berkovitz R, Yehezkel S, Shahar H, Selig S, Skorecki K.

BMC Cell Biol. 2011 Apr 15;12:16. doi: 10.1186/1471-2121-12-16.

39.

Validating transcripts with probes and imaging technology.

Itzkovitz S, van Oudenaarden A.

Nat Methods. 2011 Apr;8(4 Suppl):S12-9. doi: 10.1038/nmeth.1573. Epub 2011 Mar 30. Review.

40.

Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress--implications for tissue and organismal aging.

Shlush LI, Skorecki KL, Itzkovitz S, Yehezkel S, Segev Y, Shachar H, Berkovitz R, Adir Y, Vulto I, Lansdorp PM, Selig S.

Mech Ageing Dev. 2011 Mar;132(3):123-30. doi: 10.1016/j.mad.2011.01.005. Epub 2011 Feb 12.

PMID:
21320523
41.

Overlapping codes within protein-coding sequences.

Itzkovitz S, Hodis E, Segal E.

Genome Res. 2010 Nov;20(11):1582-9. doi: 10.1101/gr.105072.110. Epub 2010 Sep 14.

42.

Invariant distribution of promoter activities in Escherichia coli.

Zaslaver A, Kaplan S, Bren A, Jinich A, Mayo A, Dekel E, Alon U, Itzkovitz S.

PLoS Comput Biol. 2009 Oct;5(10):e1000545. doi: 10.1371/journal.pcbi.1000545. Epub 2009 Oct 23.

43.

Multiparametric analysis of focal adhesion formation by RNAi-mediated gene knockdown.

Winograd-Katz SE, Itzkovitz S, Kam Z, Geiger B.

J Cell Biol. 2009 Aug 10;186(3):423-36. doi: 10.1083/jcb.200901105.

44.

Population mixture model for nonlinear telomere dynamics.

Itzkovitz S, Shlush LI, Gluck D, Skorecki K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Dec;78(6 Pt 1):060902. Epub 2008 Dec 23.

PMID:
19256795
45.

Using expression profiles of Caenorhabditis elegans neurons to identify genes that mediate synaptic connectivity.

Baruch L, Itzkovitz S, Golan-Mashiach M, Shapiro E, Segal E.

PLoS Comput Biol. 2008 Jul 11;4(7):e1000120. doi: 10.1371/journal.pcbi.1000120.

46.

Cell lineage analysis of a mouse tumor.

Frumkin D, Wasserstrom A, Itzkovitz S, Stern T, Harmelin A, Eilam R, Rechavi G, Shapiro E.

Cancer Res. 2008 Jul 15;68(14):5924-31. doi: 10.1158/0008-5472.CAN-07-6216.

47.

Geometric constraints on neuronal connectivity facilitate a concise synaptic adhesive code.

Itzkovitz S, Baruch L, Shapiro E, Segal E.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9278-83. doi: 10.1073/pnas.0712207105. Epub 2008 Jun 26.

48.

The Druze: a population genetic refugium of the Near East.

Shlush LI, Behar DM, Yudkovsky G, Templeton A, Hadid Y, Basis F, Hammer M, Itzkovitz S, Skorecki K.

PLoS One. 2008 May 7;3(5):e2105. doi: 10.1371/journal.pone.0002105.

49.

Estimating cell depth from somatic mutations.

Wasserstrom A, Frumkin D, Adar R, Itzkovitz S, Stern T, Kaplan S, Shefer G, Shur I, Zangi L, Reizel Y, Harmelin A, Dor Y, Dekel N, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E.

PLoS Comput Biol. 2008 May 9;4(4):e1000058. doi: 10.1371/journal.pcbi.1000058.

50.

Reconstruction of cell lineage trees in mice.

Wasserstrom A, Adar R, Shefer G, Frumkin D, Itzkovitz S, Stern T, Shur I, Zangi L, Kaplan S, Harmelin A, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E.

PLoS One. 2008 Apr 9;3(4):e1939. doi: 10.1371/journal.pone.0001939.

Supplemental Content

Loading ...
Support Center