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Items: 7

1.

A novel orally available delta-5 desaturase inhibitor prevents atherosclerotic lesions accompanied with changes of fatty acid composition and eicosanoid production in ApoE knockout mice.

Takagahara S, Shinohara H, Itokawa S, Satomi Y, Ando A, Yamamoto T, Suzuki H, Fujimoto T, Kubo K, Ikeda S.

J Pharmacol Exp Ther. 2019 Sep 5. pii: jpet.119.259846. doi: 10.1124/jpet.119.259846. [Epub ahead of print]

2.
3.

Discovery of a potent and orally available acyl-CoA: cholesterol acyltransferase inhibitor as an anti-atherosclerotic agent: (4-phenylcoumarin)acetanilide derivatives.

Ogino M, Fukui S, Nakada Y, Tokunoh R, Itokawa S, Kakoi Y, Nishimura S, Sanada T, Fuse H, Kubo K, Wada T, Marui S.

Chem Pharm Bull (Tokyo). 2011;59(10):1268-73.

4.

Quantitative evaluation of PEPT1 contribution to oral absorption of cephalexin in rats.

Hironaka T, Itokawa S, Ogawara K, Higaki K, Kimura T.

Pharm Res. 2009 Jan;26(1):40-50. doi: 10.1007/s11095-008-9703-3. Epub 2008 Sep 11.

PMID:
18784906
5.

Novel 4,1-benzoxazepine derivatives with potent squalene synthase inhibitory activities.

Miki T, Kori M, Mabuchi H, Banno H, Tozawa Ri, Nakamura M, Itokawa S, Sugiyama Y, Yukimasa H.

Bioorg Med Chem. 2002 Feb;10(2):401-14.

PMID:
11741788
6.

Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells.

Oka K, Sawamura T, Kikuta K, Itokawa S, Kume N, Kita T, Masaki T.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9535-40.

7.

TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters.

Sugiyama Y, Odaka H, Itokawa S, Ishikawa E, Tomari Y, Ikeda H.

Atherosclerosis. 1995 Nov;118(1):145-53.

PMID:
8579624

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