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Items: 1 to 50 of 2679

1.

Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor.

Yeong KY, Khaw KY, Takahashi Y, Itoh Y, Murugaiyah V, Suzuki T.

Bioorg Chem. 2019 Nov 4:103403. doi: 10.1016/j.bioorg.2019.103403. [Epub ahead of print]

PMID:
31711765
2.

15-Deoxy-Δ12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.

Takagi T, Naito Y, Mizushima K, Hirai Y, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.

Arch Biochem Biophys. 2019 Nov 5;677:108183. doi: 10.1016/j.abb.2019.108183. [Epub ahead of print]

PMID:
31704099
3.

Aging-associated impairment in metabolic compensation by subcutaneous adipose tissue promotes diet-induced fatty liver disease in mice.

Taketani H, Nishikawa T, Nakajima H, Kodo K, Sugimoto S, Aoi W, Horike SI, Meguro-Horike M, Ishiba H, Seko Y, Umemura A, Yamaguchi K, Moriguchi M, Yasui K, Itoh Y.

Diabetes Metab Syndr Obes. 2019 Aug 23;12:1473-1492. doi: 10.2147/DMSO.S214093. eCollection 2019.

4.

Local chromatin motion and transcription.

Babokhov M, Hibino K, Itoh Y, Maeshima K.

J Mol Biol. 2019 Nov 2. pii: S0022-2836(19)30614-X. doi: 10.1016/j.jmb.2019.10.018. [Epub ahead of print] Review.

PMID:
31689435
5.

Comparative study on the plasma lipid oxidation induced by peroxynitrite and peroxyl radicals and its inhibition by antioxidants.

Morita M, Naito Y, Itoh Y, Niki E.

Free Radic Res. 2019 Nov 4:1-251. doi: 10.1080/10715762.2019.1688799. [Epub ahead of print]

PMID:
31684775
6.

Accuracy of liver stiffness measurement and controlled attenuation parameter using FibroScan® M/XL probes to diagnose liver fibrosis and steatosis in patients with nonalcoholic fatty liver disease: a multicenter prospective study.

Oeda S, Takahashi H, Imajo K, Seko Y, Ogawa Y, Moriguchi M, Yoneda M, Anzai K, Aishima S, Kage M, Itoh Y, Nakajima A, Eguchi Y.

J Gastroenterol. 2019 Oct 25. doi: 10.1007/s00535-019-01635-0. [Epub ahead of print]

PMID:
31654131
7.

Early administration of pegfilgrastim for esophageal cancer treated with docetaxel, cisplatin, and fluorouracil: A phase II study.

Ishikawa T, Yasuda T, Okayama T, Dohi O, Yoshida N, Kamada K, Uchiyama K, Takagi T, Konishi H, Shiozaki A, Fujiwara H, Konishi H, Naito Y, Teramukai S, Itoh Y.

Cancer Sci. 2019 Oct 23. doi: 10.1111/cas.14218. [Epub ahead of print]

8.

Does maternal autoantibody that transfer to newborn cause disease?

Ichiwata T, Ishida M, Itoh Y, Kitamura N, Nakata K.

Respirol Case Rep. 2019 Oct 11;7(9):e00494. doi: 10.1002/rcr2.494. eCollection 2019 Dec.

9.

Comparison of the effect of light alcohol consumption on Japanese men with and without fatty liver.

Hara T, Seko Y, Iwai N, Inada Y, Tsuji T, Okuda T, Komaki T, Itoh Y, Kagawa K.

Biomed Rep. 2019 Nov;11(5):191-198. doi: 10.3892/br.2019.1242. Epub 2019 Sep 20.

10.

Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7.

Hanawa-Suetsugu K, Itoh Y, Ab Fatah M, Nishimura T, Takemura K, Takeshita K, Kubota S, Miyazaki N, Wan Mohamad Noor WNI, Inaba T, Nguyen NTH, Hamada-Nakahara S, Oono-Yakura K, Tachikawa M, Iwasaki K, Kohda D, Yamamoto M, Kitao A, Shimada A, Suetsugu S.

Nat Commun. 2019 Oct 18;10(1):4763. doi: 10.1038/s41467-019-12738-w.

11.

Effectiveness and safety of chronic hepatitis C treatment with direct-acting antivirals in patients with rheumatic diseases: A case-series.

Kida T, Umemura A, Kaneshita S, Sagawa R, Inoue T, Toyama S, Wada M, Kohno M, Oda R, Inaba T, Itoh Y, Kawahito Y.

Mod Rheumatol. 2019 Nov 5:1-7. doi: 10.1080/14397595.2019.1682787. [Epub ahead of print]

PMID:
31625432
12.

M1 macrophage is the predominant phenotype in coronary artery lesions following Kawasaki disease.

Ohashi R, Fukazawa R, Shimizu A, Ogawa S, Ochi M, Nitta T, Itoh Y.

Vasc Med. 2019 Oct 17:1358863X19878495. doi: 10.1177/1358863X19878495. [Epub ahead of print]

PMID:
31621532
13.

Computational Phase-Modulated Eyeglasses.

Itoh Y, Langlotz T, Zollmann S, Iwai D, Kiyokawa K, Amano T.

IEEE Trans Vis Comput Graph. 2019 Oct 14. doi: 10.1109/TVCG.2019.2947038. [Epub ahead of print]

PMID:
31613772
14.

Gut microbiota differences in elderly subjects between rural city Kyotango and urban city Kyoto: an age-gender-matched study.

Naito Y, Takagi T, Inoue R, Kashiwagi S, Mizushima K, Tsuchiya S, Itoh Y, Okuda K, Tsujimoto Y, Adachi A, Maruyama N, Oda Y, Matoba S.

J Clin Biochem Nutr. 2019 Sep;65(2):125-131. doi: 10.3164/jcbn.19-26. Epub 2019 Aug 9.

15.

High-dose-rate intracavitary brachytherapy for recurrent cervical cancer in the vaginal stump after hysterectomy.

Kozai Y, Itoh Y, Kawamura M, Nakahara R, Ito J, Okada T, Kikkawa F, Ikeda M, Naganawa S.

Nagoya J Med Sci. 2019 Aug;81(3):351-358. doi: 10.18999/nagjms.81.3.351.

16.

Safety and efficacy of PD-1/PD-L1 blockade in patients with preexisting antinuclear antibodies.

Sakakida T, Ishikawa T, Chihara Y, Harita S, Uchino J, Tabuchi Y, Komori S, Asai J, Narukawa T, Arai A, Tsunezuka H, Kosuga T, Konishi H, Moriguchi M, Yasuda H, Hongo F, Inoue M, Hirano S, Ukimura O, Itoh Y, Taguchi T, Takayama K.

Clin Transl Oncol. 2019 Oct 1. doi: 10.1007/s12094-019-02214-8. [Epub ahead of print]

PMID:
31576495
17.

PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes.

Siddique SM, Kubouchi K, Shinmichi Y, Sawada N, Sugiura R, Itoh Y, Uehara S, Nishimura K, Okamura S, Ohsaki H, Kamoshida S, Yamashita Y, Tamura S, Sonoki T, Matsuoka H, Itoh T, Mukai H.

Sci Rep. 2019 Sep 27;9(1):13977. doi: 10.1038/s41598-019-50419-2.

18.

Cross-national analysis about the difference of histopathological management in Tis and T1 colorectal cancer between Japan and Korea.

Yoshida N, Naito Y, Inada Y, Itoh Y, Lee SP, Kim JH, Sung IK, Park HS, Han HS, Nakanishi M, Kishimoto M, Lee SY.

J Anus Rectum Colon. 2019 Jan 29;3(1):18-26. doi: 10.23922/jarc.2017-031. eCollection 2019.

19.

Development of Quality Indicators of Stroke Centers and Feasibility of Their Measurement Using a Nationwide Insurance Claims Database in Japan ― J-ASPECT Study ―

Nishimura A, Nishimura K, Onozuka D, Matsuo R, Kada A, Kamitani S, Higashi T, Ogasawara K, Shimodozono M, Harada M, Hashimoto Y, Hirano T, Hoshino H, Itabashi R, Itoh Y, Iwama T, Kohriyama T, Matsumaru Y, Osato T, Sasaki M, Shiokawa Y, Shimizu H, Takekawa H, Nishi T, Uno M, Yagita Y, Ido K, Kurogi A, Kurogi R, Arimura K, Ren N, Hagihara A, Takizawa S, Arai H, Kitazono T, Miyamoto S, Minematsu K, Iihara K; J-ASPECT study collaborators.

Circ J. 2019 Oct 25;83(11):2292-2302. doi: 10.1253/circj.CJ-19-0089. Epub 2019 Sep 26.

20.

Age-Dependent Relationship Between Plasma Aβ40 and Aβ42 and Total Tau Levels in Cognitively Normal Subjects.

Lue LF, Pai MC, Chen TF, Hu CJ, Huang LK, Lin WC, Wu CC, Jeng JS, Blennow K, Sabbagh MN, Yan SH, Wang PN, Yang SY, Hatsuta H, Morimoto S, Takeda A, Itoh Y, Liu J, Xie H, Chiu MJ.

Front Aging Neurosci. 2019 Sep 3;11:222. doi: 10.3389/fnagi.2019.00222. eCollection 2019.

21.

Can image-enhanced endoscopy improve the diagnosis of Kyoto classification of gastritis in the clinical setting?

Dohi O, Majima A, Naito Y, Yoshida T, Ishida T, Azuma Y, Kitae H, Matsumura S, Mizuno N, Yoshida N, Kamada K, Itoh Y.

Dig Endosc. 2019 Sep 24. doi: 10.1111/den.13540. [Epub ahead of print] Review.

PMID:
31550395
22.

Situations Leading to Reduced Effectiveness of Current Hand Hygiene against Infectious Mucus from Influenza Virus-Infected Patients.

Hirose R, Nakaya T, Naito Y, Daidoji T, Bandou R, Inoue K, Dohi O, Yoshida N, Konishi H, Itoh Y.

mSphere. 2019 Sep 18;4(5). pii: e00474-19. doi: 10.1128/mSphere.00474-19.

23.

Impact of Relative Dose Intensity of Early-phase Lenvatinib Treatment on Therapeutic Response in Hepatocellular Carcinoma.

Takahashi A, Moriguchi M, Seko Y, Ishikawa H, Yo T, Kimura H, Fujii H, Shima T, Mitsumoto Y, Ishiba H, Takashima H, Nagao Y, Jo M, Arai M, Hara T, Okajima A, Muramatsu A, Morita A, Yoshinami N, Nakajima T, Mitsuyoshi H, Umemura A, Nishikawa T, Yamaguchi K, Itoh Y.

Anticancer Res. 2019 Sep;39(9):5149-5156. doi: 10.21873/anticanres.13710.

PMID:
31519627
24.

Local recurrence and its risk factors after cold snare polypectomy of colorectal polyps.

Murakami T, Yoshida N, Yasuda R, Hirose R, Inoue K, Dohi O, Kamada K, Uchiyama K, Konishi H, Naito Y, Morinaga Y, Kishimoto M, Konishi E, Ogiso K, Inada Y, Itoh Y.

Surg Endosc. 2019 Sep 3. doi: 10.1007/s00464-019-07072-7. [Epub ahead of print]

PMID:
31482353
25.

A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation.

Itoh Y, Koinuma D, Omata C, Ogami T, Motizuki M, Yaguchi SI, Itoh T, Miyake K, Tsutsumi S, Aburatani H, Saitoh M, Miyazono K, Miyazawa K.

J Biol Chem. 2019 Oct 18;294(42):15466-15479. doi: 10.1074/jbc.RA119.009877. Epub 2019 Sep 3.

PMID:
31481467
26.

Kurarinone from Sophora Flavescens Roots Triggers ATF4 Activation and Cytostatic Effects Through PERK Phosphorylation.

Nishikawa S, Itoh Y, Tokugawa M, Inoue Y, Nakashima KI, Hori Y, Miyajima C, Yoshida K, Morishita D, Ohoka N, Inoue M, Mizukami H, Makino T, Hayashi H.

Molecules. 2019 Aug 27;24(17). pii: E3110. doi: 10.3390/molecules24173110.

27.

Virtual histology intravascular ultrasound evaluation of coronary artery lesions within 1 year and more than 10 years after the onset of Kawasaki disease.

Watanabe M, Fukazawa R, Ogawa S, Ohkubo T, Abe M, Hashimoto K, Hashimoto Y, Itoh Y.

J Cardiol. 2019 Aug 21. pii: S0914-5087(19)30236-9. doi: 10.1016/j.jjcc.2019.06.015. [Epub ahead of print]

PMID:
31444141
28.

An alternative method for the synthesis of 2'-halogeno-1',2'-unsaturated uridine derivatives through syn-elimination of pivalic acid of 2'-halogeno- 2'-deoxy-1'-pivaloyloxyuracil nucleoside: preparation of its 2'-C-branched nucleosides.

Haraguchi K, Gen E, Kumamoto H, Itoh Y, Tanaka H.

Nucleosides Nucleotides Nucleic Acids. 2019 Aug 20:1-13. doi: 10.1080/15257770.2019.1641724. [Epub ahead of print]

PMID:
31429364
29.

Clinical features of immune-related thyroid dysfunction and its association with outcomes in patients with advanced malignancies treated by PD-1 blockade.

Sakakida T, Ishikawa T, Uchino J, Chihara Y, Komori S, Asai J, Narukawa T, Arai A, Kobayashi T, Tsunezuka H, Kosuga T, Konishi H, Hongo F, Inoue M, Hirano S, Ukimura O, Itoh Y, Taguchi T, Takayama K.

Oncol Lett. 2019 Aug;18(2):2140-2147. doi: 10.3892/ol.2019.10466. Epub 2019 Jun 12.

30.

Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys.

Arikata M, Itoh Y, Shichinohe S, Nakayama M, Ishigaki H, Kinoshita T, Le MQ, Kawaoka Y, Ogasawara K, Shimizu T.

Antiviral Res. 2019 Nov;171:104591. doi: 10.1016/j.antiviral.2019.104591. Epub 2019 Aug 14.

PMID:
31421167
31.

Helicobacter pylori eradication increases the serum high density lipoprotein cholesterol level in the infected patients with chronic gastritis: A single-center observational study.

Iwai N, Okuda T, Oka K, Hara T, Inada Y, Tsuji T, Komaki T, Inoue K, Dohi O, Konishi H, Naito Y, Itoh Y, Kagawa K.

PLoS One. 2019 Aug 16;14(8):e0221349. doi: 10.1371/journal.pone.0221349. eCollection 2019.

32.

The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity.

Itoh Y, Golden LC, Itoh N, Matsukawa MA, Ren E, Tse V, Arnold AP, Voskuhl RR.

J Clin Invest. 2019 Aug 12;130:3852-3863. doi: 10.1172/JCI126250. eCollection 2019 Aug 12.

33.

Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice.

Ushiroda C, Naito Y, Takagi T, Uchiyama K, Mizushima K, Higashimura Y, Yasukawa Z, Okubo T, Inoue R, Honda A, Matsuzaki Y, Itoh Y.

J Clin Biochem Nutr. 2019 Jul;65(1):34-46. doi: 10.3164/jcbn.18-116. Epub 2019 Apr 6.

34.

Predictors of Unsuccessful Nonoperative Management of Capitellar Osteochondritis Dissecans.

Funakoshi T, Furushima K, Miyamoto A, Kusano H, Horiuchi Y, Itoh Y.

Am J Sports Med. 2019 Sep;47(11):2691-2698. doi: 10.1177/0363546519863349. Epub 2019 Jul 26.

PMID:
31348868
35.

Intraoperative OCT Findings May Predict Postoperative Visual Outcome in Eyes with Idiopathic Macular Hole.

Inoue M, Itoh Y, Koto T, Kurimori HY, Hirakata A.

Ophthalmol Retina. 2019 Nov;3(11):962-970. doi: 10.1016/j.oret.2019.05.022. Epub 2019 May 29.

PMID:
31324587
36.

Whole abdominopelvic intensity-modulated radiation therapy for peritoneal disseminated rhabdomyosarcoma with three-year follow-up: a case report.

Kawamura M, Okudaira K, Itoh Y, Kamomae T, Nishikawa E, Muramatsu H, Takahashi Y, Yokota K, Naganawa S.

Radiat Oncol. 2019 Jul 15;14(1):127. doi: 10.1186/s13014-019-1333-x.

37.

Efficacy of precutting endoscopic mucosal resection with full or partial circumferential incision using a snare tip for difficult colorectal lesions.

Yoshida N, Inoue K, Dohi O, Yasuda R, Hirose R, Naito Y, Murakami T, Ogiso K, Inada Y, Inagaki Y, Morinaga Y, Kishimoto M, Itoh Y.

Endoscopy. 2019 Sep;51(9):871-876. doi: 10.1055/a-0956-6879. Epub 2019 Jul 15.

PMID:
31307100
38.

Linked color imaging identifies important risk factors associated with gastric cancer after successful eradication of Helicobacter pylori.

Majima A, Dohi O, Takayama S, Hirose R, Inoue K, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Itoh Y.

Gastrointest Endosc. 2019 Nov;90(5):763-769. doi: 10.1016/j.gie.2019.06.043. Epub 2019 Jul 9.

PMID:
31299258
39.

Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.

Nirwan N, Itoh Y, Singh P, Bandyopadhyay S, Vinothkumar KR, Amunts A, Saikrishnan K.

Nat Commun. 2019 Jul 11;10(1):3058. doi: 10.1038/s41467-019-11084-1.

40.

The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression.

Tassoni A, Farkhondeh V, Itoh Y, Itoh N, Sofroniew MV, Voskuhl RR.

Sci Rep. 2019 Jul 10;9(1):10010. doi: 10.1038/s41598-019-46232-6.

41.

Isotopic evidence for seasonality of microbial internal nitrogen cycles in a temperate forested catchment with heavy snowfall.

Hattori S, Nuñez Palma Y, Itoh Y, Kawasaki M, Fujihara Y, Takase K, Yoshida N.

Sci Total Environ. 2019 Nov 10;690:290-299. doi: 10.1016/j.scitotenv.2019.06.507. Epub 2019 Jul 2.

PMID:
31291607
42.

Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes.

Zeman J, Itoh Y, Kukačka Z, Rosůlek M, Kavan D, Kouba T, Jansen ME, Mohammad MP, Novák P, Valášek LS.

Nucleic Acids Res. 2019 Sep 5;47(15):8282-8300. doi: 10.1093/nar/gkz570.

43.

Small-intestinal necrosis due to non-occlusive mesenteric ischemia with diabetic ketoacidosis after quetiapine treatment.

Itoh Y, Sagawa R, Kinoshita H, Tamba S, Yamamoto K, Yamada Y, Matsuzawa Y.

Diabetol Int. 2018 Dec 5;10(3):225-230. doi: 10.1007/s13340-018-0386-7. eCollection 2019 Jul.

PMID:
31275790
44.

Evaluation of the Diabetes Regional Coordination Path using the Diabetes Coordination Notebook in community-based diabetes care.

Horikawa Y, Suzuki A, Hashimoto KI, Enya M, Nishida S, Kobayashi R, Ohashi T, Yamazaki F, Totani R, Kobayashi H, Yamamoto M, Itoh Y, Takeda J.

Diabetol Int. 2018 Oct 20;10(3):188-197. doi: 10.1007/s13340-018-0379-6. eCollection 2019 Jul.

45.

[Long-Term Survival of a Patient with Small Cell Esophageal Carcinoma Who Underwent Multidisciplinary Therapy-ACase Report].

Ota T, Ishikawa T, Hotta Y, Okayama T, Shiozaki A, Fujiwara H, Kishimoto M, Konishi H, Naito Y, Itoh Y.

Gan To Kagaku Ryoho. 2019 Jun;46(6):1053-1056. Japanese.

PMID:
31273174
46.

Raman spectroscopic histology using machine learning for nonalcoholic fatty liver disease.

Helal KM, Taylor JN, Cahyadi H, Okajima A, Tabata K, Itoh Y, Tanaka H, Fujita K, Harada Y, Komatsuzaki T.

FEBS Lett. 2019 Sep;593(18):2535-2544. doi: 10.1002/1873-3468.13520. Epub 2019 Jul 8.

PMID:
31254349
47.

Rational design using sequence information only produces a peptide that binds to the intrinsically disordered region of p53.

Kamagata K, Mano E, Itoh Y, Wakamoto T, Kitahara R, Kanbayashi S, Takahashi H, Murata A, Kameda T.

Sci Rep. 2019 Jun 28;9(1):8584. doi: 10.1038/s41598-019-44688-0.

48.

The efficacy of adding budesonide/formoterol to ipratropium plus theophylline in managing severe chronic obstructive pulmonary disease: an open-label, randomized study in China.

Huang K, Guo Y, Kang J, An L, Zheng Z, Ma L, Peng L, Wang H, Su R, Itoh Y, Wang C.

Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619853500. doi: 10.1177/1753466619853500.

49.

Alterations of Foveal Architecture during Vitrectomy for Myopic Retinoschisis Identified by Intraoperative Optical Coherence Tomography.

Itoh Y, Inoue M, Kato Y, Koto T, Hirakata A.

Ophthalmologica. 2019;242(2):87-97. doi: 10.1159/000500362. Epub 2019 Jun 14.

PMID:
31203278
50.

Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.

Mellini P, Itoh Y, Elboray EE, Tsumoto H, Li Y, Suzuki M, Takahashi Y, Tojo T, Kurohara T, Miyake Y, Miura Y, Kitao Y, Kotoku M, Iida T, Suzuki T.

J Med Chem. 2019 Jun 27;62(12):5844-5862. doi: 10.1021/acs.jmedchem.9b00255. Epub 2019 Jun 12.

PMID:
31144814

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