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Artificial Intelligence-assisted System Improves Endoscopic Identification of Colorectal Neoplasms.

Kudo SE, Misawa M, Mori Y, Hotta K, Ohtsuka K, Ikematsu H, Saito Y, Takeda K, Nakamura H, Ichimasa K, Ishigaki T, Toyoshima N, Kudo T, Hayashi T, Wakamura K, Baba T, Fumio I, Inoue H, Itoh H, Oda M, Mori K.

Clin Gastroenterol Hepatol. 2019 Sep 13. pii: S1542-3565(19)30997-8. doi: 10.1016/j.cgh.2019.09.009. [Epub ahead of print]


Difference in Z scores of placental weight and fetal/placental weight ratio by mode of delivery.

Matsuda Y, Itoh T, Okada E, Sasaki K, Itoh H, Kanayama N.

J Obstet Gynaecol Res. 2019 Sep 15. doi: 10.1111/jog.14117. [Epub ahead of print]


Efficacy and safety of once-weekly exenatide after switching from twice-daily exenatide in patients with type 2 diabetes.

Watanabe Y, Saisho Y, Inaishi J, Kou K, Yamauchi A, Kanazawa Y, Okubo Y, Tokui M, Imai T, Murakami R, Tsuchiya T, Sasaki H, Masaoka T, Irie J, Meguro S, Itoh H; Twin-exenatide Study Group.

J Diabetes Investig. 2019 Sep 13. doi: 10.1111/jdi.13146. [Epub ahead of print]


Low birth weight is associated with decline in renal function in Japanese male and female adolescents.

Murai-Takeda A, Kanda T, Azegami T, Hirose H, Inokuchi M, Tokuyama H, Wakino S, Tokumura M, Kawabe H, Mori M, Itoh H.

Clin Exp Nephrol. 2019 Sep 7. doi: 10.1007/s10157-019-01784-9. [Epub ahead of print]


Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids.

Miyamoto J, Igarashi M, Watanabe K, Karaki SI, Mukouyama H, Kishino S, Li X, Ichimura A, Irie J, Sugimoto Y, Mizutani T, Sugawara T, Miki T, Ogawa J, Drucker DJ, Arita M, Itoh H, Kimura I.

Nat Commun. 2019 Sep 5;10(1):4007. doi: 10.1038/s41467-019-11978-0.


Relationships between endogenous CYP3A markers and plasma amlodipine exposure and metabolism in early postpartum and non-peripartum women with hypertension.

Taguchi R, Naito T, Kubono N, Ogawa N, Itoh H, Kawakami J.

Pregnancy Hypertens. 2019 Jul;17:209-215. doi: 10.1016/j.preghy.2019.07.002. Epub 2019 Jul 4.


Vaccine Development against the Renin-Angiotensin System for the Treatment of Hypertension.

Azegami T, Itoh H.

Int J Hypertens. 2019 Aug 14;2019:9218531. doi: 10.1155/2019/9218531. eCollection 2019. Review.


Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan.

Fujii Y, Takeda Y, Kurihara I, Itoh H, Katabami T, Ichijo T, Wada N, Shibayama Y, Yoshimoto T, Ogawa Y, Kawashima J, Sone M, Inagaki N, Takahashi K, Watanabe M, Matsuda Y, Kobayashi H, Shibata H, Kamemura K, Otsuki M, Yamamto K, Ogo A, Yanase T, Okamura S, Miyauchi S, Fujita M, Suzuki T, Umakoshi H, Ogasawara T, Tsuiki M, Naruse M; JPAS Study Group.

J Hum Hypertens. 2019 Aug 28. doi: 10.1038/s41371-019-0229-4. [Epub ahead of print]


Withdrawal of the 1999 JSOG recommendation of weight gain restriction during pregnancy (Commentary of the JSOG Perinatal Committee).

Itoh H, Itakura A, Kanayama N, Ikeda T.

J Obstet Gynaecol Res. 2019 Aug 27. doi: 10.1111/jog.14080. [Epub ahead of print] No abstract available.


Correction to: Role of anemia and proteinuria in the development of subsequent renal function deterioration in a general population with preserved glomerular filtration rate: a community-based cohort study.

Kiriyama H, Kaneko H, Itoh H, Yoshida Y, Nakanishi K, Mizuno Y, Daimon M, Morita H, Yatomi Y, Komuro I.

J Nephrol. 2019 Aug 19. doi: 10.1007/s40620-019-00635-w. [Epub ahead of print]


Effects of work schedule and period of exposure on changes in urinary chromium and nickel excretion among rotating shift workers in a stainless-steel plant.

Itoh H, Wang RS, Maki S, Niu Q, Shang H, Su Y, Weng Z, Saito H, Miura N, Takahashi M.

Chronobiol Int. 2019 Oct;36(10):1439-1446. doi: 10.1080/07420528.2019.1645159. Epub 2019 Aug 1.


Treatment preference for weekly versus daily DPP-4 inhibitors in patients with type 2 diabetes mellitus: outcomes from the TRINITY trial.

Meguro S, Matsui S, Itoh H.

Curr Med Res Opin. 2019 Aug 22:1-8. doi: 10.1080/03007995.2019.1651130. [Epub ahead of print]


Successful determination of nilotinib dosage by therapeutic drug monitoring in a patient with chronic myeloid leukemia developing hepatic dysfunction: A case report.

Nakahara R, Sumimoto T, Ogata M, Sato Y, Itoh H.

Clin Case Rep. 2019 Jun 14;7(7):1419-1421. doi: 10.1002/ccr3.2191. eCollection 2019 Jul.


Association Between Acute Fall in Estimated Glomerular Filtration Rate After Treatment for Primary Aldosteronism and Long-Term Decline in Renal Function.

Kobayashi H, Abe M, Nakamura Y, Takahashi K, Fujita M, Takeda Y, Yoneda T, Kurihara I, Itoh H, Tsuiki M, Wada N, Ichijo T, Katabami T, Ogawa Y, Kawashima J, Yoshimoto T, Sone M, Inagaki N, Watanabe M, Kamemura K, Matsuda Y, Izawa S, Tanabe M, Tanabe A, Suzuki T, Naruse M; JPAS/JRAS Study Group.

Hypertension. 2019 Sep;74(3):630-638. doi: 10.1161/HYPERTENSIONAHA.119.13131. Epub 2019 Jul 22.


Renal impairment is closely associated with plasma aldosterone concentration in patients with primary aldosteronism.

Kawashima A, Sone M, Inagaki N, Takeda Y, Itoh H, Kurihara I, Umakoshi H, Ichijo T, Katabami T, Wada N, Ogawa Y, Kawashima J, Fujita M, Miyauchi S, Okamura S, Fukuoka T, Yanase T, Izawa S, Yoshikawa Y, Hashimoto S, Yamada M, Kai T, Suzuki T, Naruse M.

Eur J Endocrinol. 2019 Jul 1. pii: EJE-19-0047.R2. doi: 10.1530/EJE-19-0047. [Epub ahead of print]


Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E.

Itoh H, Tokumoto K, Kaji T, Paudel A, Panthee S, Hamamoto H, Sekimizu K, Inoue M.

Nat Commun. 2019 Jul 5;10(1):2992. doi: 10.1038/s41467-019-10754-4.


Cost-Effectiveness of Cardiac Rehabilitation in Patients with Coronary Artery Disease: A Meta-Analysis.

Takura T, Ebata-Kogure N, Goto Y, Kohzuki M, Nagayama M, Oikawa K, Koyama T, Itoh H.

Cardiol Res Pract. 2019 Jun 4;2019:1840894. doi: 10.1155/2019/1840894. eCollection 2019. Review.


Greeting Messages from President of Japanese Society of Hypertension (JSH) The challenge of JSH: moonshot for "Conquest of hypertension in Japan".

Itoh H.

Hypertens Res. 2019 Jul;42(7):925-927. doi: 10.1038/s41440-019-0279-6. Epub 2019 Jul 5. No abstract available.


National burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in Japan.

Itoh H, Saito T, Nojiri S, Hiratsuka Y, Yokoyama K.

Health Econ Rev. 2019 Jun 29;9(1):20. doi: 10.1186/s13561-019-0238-6.


Comparative genome-wide analysis of gastric adenocarcinomas with hyperplastic polyp components.

Takayama Y, Ono Y, Mizukami Y, Itoh H, Nakajima N, Arai H, Tanaka S, Nobusawa S, Yokoo H, Onozato Y.

Virchows Arch. 2019 Sep;475(3):383-389. doi: 10.1007/s00428-019-02592-y. Epub 2019 Jun 28.


DNA Damage Repair and DNA Methylation in the Kidney.

Hayashi K, Hishikawa A, Itoh H.

Am J Nephrol. 2019;50(2):81-91. doi: 10.1159/000501356. Epub 2019 Jun 26. Review.


Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study.

Itoh H, Ito S, Rakugi H, Okuda Y, Nishioka S.

Hypertens Res. 2019 Jun 25. doi: 10.1038/s41440-019-0270-2. [Epub ahead of print]


Population Pharmacokinetics and Pharmacodynamics of Apixaban Linking Its Plasma Concentration to Intrinsic Activated Coagulation Factor X Activity in Japanese Patients with Atrial Fibrillation.

Ueshima S, Hira D, Tomitsuka C, Nomura M, Kimura Y, Yamane T, Tabuchi Y, Ozawa T, Itoh H, Horie M, Terada T, Katsura T.

AAPS J. 2019 Jun 24;21(5):80. doi: 10.1208/s12248-019-0353-7.


Hypertension as a Metabolic Disorder and the Novel Role of the Gut.

Tanaka M, Itoh H.

Curr Hypertens Rep. 2019 Jun 24;21(8):63. doi: 10.1007/s11906-019-0964-5. Review.


Full solid-phase total synthesis of macrocyclic natural peptides using four-dimensionally orthogonal protective groups.

Itoh H, Inoue M.

Org Biomol Chem. 2019 Jul 21;17(27):6519-6527. doi: 10.1039/c9ob01130g. Epub 2019 Jun 24.


Effect of Metabolically Healthy Obesity on the Development of Carotid Plaque in the General Population: A Community-Based Cohort Study.

Itoh H, Kaneko H, Kiriyama H, Yoshida Y, Nakanishi K, Mizuno Y, Daimon M, Morita H, Yatomi Y, Yamamichi N, Komuro I.

J Atheroscler Thromb. 2019 Jun 22. doi: 10.5551/jat.48728. [Epub ahead of print]


Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment-Two Case Reports.

Ryuzaki M, Tokuyama H, Uchiyama K, Nakaya H, Hasegawa K, Miyashita K, Konishi K, Hashiguchi A, Wakino S, Itoh H.

Clin Med Insights Case Rep. 2019 Jun 13;12:1179547619853647. doi: 10.1177/1179547619853647. eCollection 2019.


Effect of cigarette smoking on carotid artery atherosclerosis: a community-based cohort study.

Kiriyama H, Kaneko H, Itoh H, Yoshida Y, Nakanishi K, Mizuno Y, Daimon M, Morita H, Yamamichi N, Komuro I.

Heart Vessels. 2019 Jun 20. doi: 10.1007/s00380-019-01455-5. [Epub ahead of print]


Comparison of performance characteristics between high-performance liquid chromatography and latex agglutination turbidimetric immunoassay for therapeutic drug monitoring of zonisamide.

Eto D, Tanaka R, Suzuki Y, Sato Y, Itoh H.

J Clin Lab Anal. 2019 Jun 20:e22940. doi: 10.1002/jcla.22940. [Epub ahead of print]


Left Main Coronary Artery Obstruction by Huge Noncoronary Cusp Calcification After Transcatheter Aortic ValveĀ Replacement.

Kiriyama H, Kaneko H, Itoh H, Uehara M, Kodera S, Kiyosue A, Yamauchi H, Daimon M, Ando J, Morita H, Ono M, Komuro I.

JACC Cardiovasc Interv. 2019 Jul 8;12(13):1285-1287. doi: 10.1016/j.jcin.2019.01.243. Epub 2019 Jun 12. No abstract available.


Elevated bradykinin receptor type 1 expression in postpartum acute myometritis: Possible involvement in augmented interstitial edema of the atonic gravid uterus.

Shen Y, Oda T, Tamura N, Kohmura-Kobayashi Y, Furuta-Isomura N, Yaguchi C, Uchida T, Suzuki K, Itoh H, Kanayama N.

J Obstet Gynaecol Res. 2019 Aug;45(8):1553-1561. doi: 10.1111/jog.14012. Epub 2019 Jun 10.


Interstitial Lung Disease with Anti-melanoma Differentiation-associated Protein 5 Antibody: Rapidly Progressive Perilobular Opacity.

Chino H, Sekine A, Baba T, Kitamura H, Iwasawa T, Okudela K, Takemura T, Itoh H, Sato S, Suzuki Y, Ogura T.

Intern Med. 2019 Jun 7. doi: 10.2169/internalmedicine.2328-18. [Epub ahead of print]


Intrauterine Fetal and Neonatal Death between Small for Date and Non-Small for Date in Small for Gestational Age Infants.

Itoh T, Matsuda Y, Itoh H, Ogawa M, Sasaki K, Kanayama N.

Int J Med Sci. 2019 Mar 9;16(4):501-506. doi: 10.7150/ijms.31153. eCollection 2019.


Relation between the Updated Blood Pressure Classification according to the American College of Cardiology/American Heart Association Guidelines and Carotid Intima-Media Thickness.

Itoh H, Kaneko H, Kiriyama H, Yoshida Y, Nakanishi K, Mizuno Y, Daimon M, Morita H, Yatomi Y, Komuro I.

Am J Cardiol. 2019 Aug 1;124(3):396-401. doi: 10.1016/j.amjcard.2019.04.054. Epub 2019 May 9.


Burkholderia Gut Symbionts Associated with European and Japanese Populations of the Dock Bug Coreus marginatus (Coreoidea: Coreidae).

Ohbayashi T, Itoh H, Lachat J, Kikuchi Y, Mergaert P.

Microbes Environ. 2019 Jun 27;34(2):219-222. doi: 10.1264/jsme2.ME19011. Epub 2019 Jun 6.


[Clinical Approach to Individualization of Antimicrobial Therapy Based on Pharmacokinetic/Pharmacodynamic Analysis and Therapeutic Drug Monitoring].

Sato Y, Suzuki Y, Tanaka R, Kaneko T, Itoh H.

Yakugaku Zasshi. 2019;139(6):917-922. doi: 10.1248/yakushi.18-00213-3. Review. Japanese.


Vertical distribution of particle-associated and free-living ammonia-oxidizing archaea in Suruga Bay, a deep coastal embayment of Japan.

Ijichi M, Itoh H, Hamasaki K.

Arch Microbiol. 2019 May 30. doi: 10.1007/s00203-019-01680-6. [Epub ahead of print]


Efficacy and safety of esaxerenone (CS-3150) for the treatment of essential hypertension: a phase 2 randomized, placebo-controlled, double-blind study.

Ito S, Itoh H, Rakugi H, Okuda Y, Yamakawa S.

J Hum Hypertens. 2019 Jul;33(7):542-551. doi: 10.1038/s41371-019-0207-x. Epub 2019 May 21.


High-sensitivity simultaneous quantification of tacrolimus and 13-O-demethyl tacrolimus in human whole blood using ultra-performance liquid chromatography coupled to tandem mass spectrometry.

Ono H, Suzuki Y, Kaneko T, Tanaka R, Sato F, Sato Y, Mimata H, Itoh H.

Biomed Chromatogr. 2019 Sep;33(9):e4584. doi: 10.1002/bmc.4584. Epub 2019 Jun 6.


Draft Genome Sequence of Agarivorans sp. Strain Toyoura001, Isolated from an Abalone Gut.

Itoh H, Kawano K, Kihara M.

Microbiol Resour Announc. 2019 May 9;8(19). pii: e00169-19. doi: 10.1128/MRA.00169-19.


A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid.

Yasuda I, Hasegawa K, Tokuyama H, Washida N, Shinozuka K, Yasuda M, Ryuzaki M, Urai H, Wakino S, Itoh H.

Clin Med Insights Case Rep. 2019 Apr 29;12:1179547619846860. doi: 10.1177/1179547619846860. eCollection 2019.


Influence of antihypertensive drugs in the subtype diagnosis of primary aldosteronism by adrenal venous sampling.

Nagasawa M, Yamamoto K, Rakugi H, Takeda M, Akasaka H, Umakoshi H, Tsuiki M, Takeda Y, Kurihara I, Itoh H, Ichijo T, Katabami T, Wada N, Shibayama Y, Yoshimoto T, Ogawa Y, Kawashima J, Sone M, Inagaki N, Takahashi K, Fujita M, Watanabe M, Matsuda Y, Kobayashi H, Shibata H, Kamemura K, Otsuki M, Fujii Y, Ogo A, Okamura S, Miyauchi S, Yanase T, Suzuki T, Kawamura T, Naruse M; JPAS Study Group.

J Hypertens. 2019 Jul;37(7):1493-1499. doi: 10.1097/HJH.0000000000002047.


High Prevalence of Diabetes in Patients With Primary Aldosteronism (PA) Associated With Subclinical Hypercortisolism and Prediabetes More Prevalent in Bilateral Than Unilateral PA: A Large, Multicenter Cohort Study in Japan.

Akehi Y, Yanase T, Motonaga R, Umakoshi H, Tsuiki M, Takeda Y, Yoneda T, Kurihara I, Itoh H, Katabami T, Ichijo T, Wada N, Shibayama Y, Yoshimoto T, Ashida K, Ogawa Y, Kawashima J, Sone M, Inagaki N, Takahashi K, Fujita M, Watanabe M, Matsuda Y, Kobayashi H, Shibata H, Kamemura K, Otsuki M, Fujii Y, Yamamoto K, Ogo A, Okamura S, Miyauchi S, Fukuoka T, Izawa S, Hashimoto S, Yamada M, Yoshikawa Y, Kai T, Suzuki T, Kawamura T, Naruse M; Japan Primary Aldosteronism Study Group.

Diabetes Care. 2019 May;42(5):938-945. doi: 10.2337/dc18-1293.


Microscopic heat pulses activate cardiac thin filaments.

Ishii S, Oyama K, Arai T, Itoh H, Shintani SA, Suzuki M, Kobirumaki-Shimozawa F, Terui T, Fukuda N, Ishiwata S.

J Gen Physiol. 2019 Jun 3;151(6):860-869. doi: 10.1085/jgp.201812243. Epub 2019 Apr 22.


MicroRNA-204-5p: A novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma.

Kurahashi R, Kadomatsu T, Baba M, Hara C, Itoh H, Miyata K, Endo M, Morinaga J, Terada K, Araki K, Eto M, Schmidt LS, Kamba T, Linehan WM, Oike Y.

Cancer Sci. 2019 Jun;110(6):1897-1908. doi: 10.1111/cas.14026. Epub 2019 May 24.


Serum S100A8/A9 as a Potentially Sensitive Biomarker for Inflammatory Bowel Disease.

Okada K, Okabe M, Kimura Y, Itoh H, Ikemoto M.

Lab Med. 2019 Apr 17. pii: lmz003. doi: 10.1093/labmed/lmz003. [Epub ahead of print]


JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration.

Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Apr 8. doi: 10.1038/s41440-019-0261-3. [Epub ahead of print] No abstract available.


Role of anemia and proteinuria in the development of subsequent renal function deterioration in a general population with preserved glomerular filtration rate: a community-based cohort study.

Kiriyama H, Kaneko H, Itoh H, Yoshida Y, Nakanishi K, Mizuno Y, Daimon M, Morita H, Yatomi Y, Komuro I.

J Nephrol. 2019 Apr 6. doi: 10.1007/s40620-019-00605-2. [Epub ahead of print] Erratum in: J Nephrol. 2019 Aug 19;:.


Comprehensive Structure-Activity Relationship Studies of Macrocyclic Natural Products Enabled by Their Total Syntheses.

Itoh H, Inoue M.

Chem Rev. 2019 Sep 11;119(17):10002-10031. doi: 10.1021/acs.chemrev.9b00063. Epub 2019 Apr 4.


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