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Endoscopic transpapillary gallbladder drainage using the balloon occlusion method to advance the guidewire into the cystic duct.

Nakahara K, Michikawa Y, Morita R, Suetani K, Kobayashi S, Otsubo T, Itoh F.

Endoscopy. 2020 Mar 18. doi: 10.1055/a-1125-5826. [Epub ahead of print] No abstract available.


A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report.

Morita N, Okuse C, Suetani K, Nakano H, Hiraishi T, Ishigooka S, Mori S, Shimamura T, Asakura T, Koike J, Itoh F, Suzuki M.

BMC Gastroenterol. 2020 Jan 13;20(1):9. doi: 10.1186/s12876-020-1162-2.


Endoscopic transpapillary gallbladder stenting using a newly designed plastic stent for acute cholecystitis.

Nakahara K, Michikawa Y, Morita R, Suetani K, Morita N, Sato J, Tsuji K, Ikeda H, Matsunaga K, Watanabe T, Matsumoto N, Kobayashi S, Otsubo T, Itoh F.

Endosc Int Open. 2019 Sep;7(9):E1105-E1114. doi: 10.1055/a-0747-5668. Epub 2019 Aug 29.


Delayed perforation after endoscopic band ligation for colonic diverticular hemorrhage.

Sato Y, Yasuda H, Fukuoka A, Kiyokawa H, Kato M, Yamashita M, Matsuo Y, Yamamoto H, Otsubo T, Itoh F.

Clin J Gastroenterol. 2020 Feb;13(1):6-10. doi: 10.1007/s12328-019-01027-0. Epub 2019 Aug 1.


Washing cytology of removed self-expandable metal stent for biliary stricture: A novel cytology technique.

Nakahara K, Morita R, Michikawa Y, Suetani K, Tsuji K, Sato J, Endo A, Ariizumi Y, Takagi M, Itoh F.

Diagn Cytopathol. 2019 Jul;47(7):743-745. doi: 10.1002/dc.24206. Epub 2019 May 6. No abstract available.


Length of lags in responses of milk yield and somatic cell score on test day to heat stress in Holsteins.

Hagiya K, Bamba I, Osawa T, Atagi Y, Takusari N, Itoh F, Yamazaki T.

Anim Sci J. 2019 May;90(5):613-618. doi: 10.1111/asj.13186. Epub 2019 Feb 27.


Endoscopic Sphincterotomy before Fully Covered Metal Stent Placement Is Not Required for Distal Malignant Biliary Stricture due to a Pancreatic Head Tumor.

Nakahara K, Michikawa Y, Morita R, Suetani K, Morita N, Sato J, Tsuji K, Ikeda H, Matsunaga K, Watanabe T, Matsumoto N, Kobayashi S, Otsubo T, Itoh F.

Gastroenterol Res Pract. 2019 Jan 15;2019:9675347. doi: 10.1155/2019/9675347. eCollection 2019.


PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling.

Ikeno S, Nakano N, Sano K, Minowa T, Sato W, Akatsu R, Sakata N, Hanagata N, Fujii M, Itoh F, Itoh S.

J Biol Chem. 2019 Mar 29;294(13):4966-4980. doi: 10.1074/jbc.RA118.004153. Epub 2019 Feb 4.


Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review.

Yasuda H, Nakagawa M, Kiyokawa H, Yoshida E, Yoshimura T, Koshikawa N, Itoh F, Seiki M.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E226. doi: 10.3390/ijms20010226. Review.


Daclatasvir and asunaprevir improves health-related quality of life in Japanese patients infected with hepatitis C virus.

Ikeda H, Watanabe T, Matsumoto N, Hiraishi T, Nakano H, Noguchi Y, Hattori N, Shigefuku R, Yamashita M, Nakahara K, Matsunaga K, Okuse C, Yotsuyanagi H, Tanaka A, Suzuki M, Itoh F.

JGH Open. 2018 May 14;2(3):87-92. doi: 10.1002/jgh3.12052. eCollection 2018 Jun.


Efficacy of Combined Thrombomodulin and Antithrombin in Anticoagulant Therapy for Acute Cholangitis-induced Disseminated Intravascular Coagulation.

Morita N, Nakahara K, Morita R, Suetani K, Michikawa Y, Sato J, Tsuji K, Ikeda H, Matsunaga K, Watanabe T, Matsumoto N, Okuse C, Suzuki M, Itoh F.

Intern Med. 2019 Apr 1;58(7):907-914. doi: 10.2169/internalmedicine.1923-18. Epub 2018 Nov 19.


Endoscopic small-capacity forceps increase the pathological diagnosis of gastric indefinite neoplasia.

Matsuo Y, Yasuda H, Kato M, Kiyokawa H, Ozawa M, Sato Y, Ikeda Y, Ozawa SI, Yamashita M, Fujino T, Yamamoto H, Takagi M, Itoh F.

Turk J Gastroenterol. 2018 Jul;29(4):481-487. doi: 10.5152/tjg.2018.17347.


Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis.

Sato J, Nakahara K, Morita R, Morita N, Suetani K, Michikawa Y, Kobayashi S, Itoh F.

Can J Gastroenterol Hepatol. 2018 Aug 8;2018:3145107. doi: 10.1155/2018/3145107. eCollection 2018.


Diagnostic Ability of Endoscopic Bile Cytology Using a Newly Designed Biliary Scraper for Biliary Strictures.

Nakahara K, Michikawa Y, Morita R, Suetani K, Morita N, Sato J, Tsuji K, Ikeda H, Matsunaga K, Watanabe T, Matsumoto N, Kobayashi S, Otsubo T, Itoh F.

Dig Dis Sci. 2019 Jan;64(1):241-248. doi: 10.1007/s10620-018-5217-y. Epub 2018 Jul 23.


Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment.

Wakasugi H, Takahashi H, Niinuma T, Kitajima H, Oikawa R, Matsumoto N, Takeba Y, Otsubo T, Takagi M, Ariizumi Y, Suzuki M, Okuse C, Iwabuchi S, Nakano M, Akutsu N, Kang JH, Matsui T, Yamada N, Sasaki H, Yamamoto E, Kai M, Sasaki Y, Sasaki S, Tanaka Y, Yotsuyanagi H, Tsutsumi T, Yamamoto H, Tokino T, Nakase H, Suzuki H, Itoh F.

Cancer Lett. 2018 Oct 10;434:91-100. doi: 10.1016/j.canlet.2018.07.019. Epub 2018 Jul 17.


Esophagogastric varices were diagnosed in a non-cirrhotic liver case during long-term follow-up after oxaliplatin-based chemotherapy.

Shigefuku R, Watanabe T, Mizukami T, Matsunaga K, Hattori N, Ehira T, Suzuki T, Nakano H, Sato Y, Matsuo Y, Nakahara K, Ikeda H, Matsumoto N, Tsuda T, Katayama M, Koizumi S, Okuse C, Suzuki M, Otsubo T, Nakajima TE, Yasuda H, Itoh F.

Clin J Gastroenterol. 2018 Dec;11(6):487-492. doi: 10.1007/s12328-018-0873-1. Epub 2018 Jun 11.


TMEPAI family: involvement in regulation of multiple signalling pathways.

Itoh S, Itoh F.

J Biochem. 2018 Sep 1;164(3):195-204. doi: 10.1093/jb/mvy059. Review.


GNAS-mutated carcinoma arising from gastric foveolar metaplasia in the duodenum after 9 years of observation.

Matsuo Y, Yamamoto H, Sato Y, Oikawa R, Maehata T, Fujino T, Yahagi N, Yasuda H, Takagi M, Itoh F.

Clin J Gastroenterol. 2018 Oct;11(5):391-395. doi: 10.1007/s12328-018-0856-2. Epub 2018 Mar 31.


Efficacy of ledipasvir/sofosbuvir with or without ribavirin for 12 weeks in genotype 1b HCV patients previously treated with a nonstructural protein 5A inhibitor-containing regimen.

Ikeda H, Watanabe T, Shimizu H, Hiraishi T, Kaneko R, Baba T, Takahashi H, Matsunaga K, Matsumoto N, Yasuda H, Okuse C, Iwabuchi S, Suzuki M, Itoh F.

Hepatol Res. 2018 Sep;48(10):802-809. doi: 10.1111/hepr.13074. Epub 2018 May 4.


Enrichment of Helicobacter pylori mutant strains after eradication therapy analyzed by gastric wash-based quantitative pyrosequencing.

Oikawa R, Watanabe Y, Miyamoto S, Sato Y, Ono S, Mabe K, Yamamoto H, Kato M, Itoh F.

Tumour Biol. 2017 Oct;39(10):1010428317734865. doi: 10.1177/1010428317734865.


Fusobacterium nucleatum detected simultaneously in a pyogenic liver abscess and advanced sigmoid colon cancer.

Shigefuku R, Watanabe T, Kanno Y, Ikeda H, Nakano H, Hattori N, Matsunaga K, Matsumoto N, Kanno SI, Nosho K, Hachiya A, Iwatani Y, Matsumori T, Tsukikawa S, Makizumi R, Otsubo T, Yamamoto H, Itoh F.

Anaerobe. 2017 Dec;48:144-146. doi: 10.1016/j.anaerobe.2017.08.010. Epub 2017 Aug 16.


Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Imaeda T, Ono K, Nakai K, Hori Y, Matsukawa J, Takagi T, Fujioka Y, Tarui N, Kondo M, Imanishi A, Inatomi N, Kajino M, Itoh F, Nishida H.

Bioorg Med Chem. 2017 Jul 15;25(14):3719-3735. doi: 10.1016/j.bmc.2017.05.012. Epub 2017 May 6.


Two Cases of Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome with High Serum Procalcitonin Levels, Including the First Case Complicated with Adrenal Hemorrhaging.

Nara M, Komatsuda A, Itoh F, Kaga H, Saitoh M, Togashi M, Kameoka Y, Wakui H, Takahashi N.

Intern Med. 2017;56(10):1247-1252. doi: 10.2169/internalmedicine.56.7991. Epub 2017 May 15.


Curative Effects for B-Cell Lymphoma Accomplished by Direct-Acting Antiviral Agents of Hepatitis C.

Hattori N, Ikeda H, Nakano H, Matsumoto N, Watanabe T, Shigefuku R, Noguchi Y, Matsunaga K, Sakai H, Okuse C, Yamamoto H, Miura I, Suzuki M, Itoh F.

Open Forum Infect Dis. 2017 Mar 25;4(2):ofx057. doi: 10.1093/ofid/ofx057. eCollection 2017 Spring.


Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion.

Nishida H, Fujimori I, Arikawa Y, Hirase K, Ono K, Nakai K, Inatomi N, Hori Y, Matsukawa J, Fujioka Y, Imanishi A, Fukui H, Itoh F.

Bioorg Med Chem. 2017 Jul 1;25(13):3447-3460. doi: 10.1016/j.bmc.2017.04.034. Epub 2017 Apr 27.


Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Nishida H, Arikawa Y, Hirase K, Imaeda T, Inatomi N, Hori Y, Matsukawa J, Fujioka Y, Hamada T, Iida M, Nishitani M, Imanishi A, Fukui H, Itoh F, Kajino M.

Bioorg Med Chem. 2017 Jul 1;25(13):3298-3314. doi: 10.1016/j.bmc.2017.04.014. Epub 2017 Apr 13.


Serum monomeric laminin-γ2 as a novel biomarker for hepatocellular carcinoma.

Kiyokawa H, Yasuda H, Oikawa R, Okuse C, Matsumoto N, Ikeda H, Watanabe T, Yamamoto H, Itoh F, Otsubo T, Yoshimura T, Yoshida E, Nakagawa M, Koshikawa N, Seiki M.

Cancer Sci. 2017 Jul;108(7):1432-1439. doi: 10.1111/cas.13261. Epub 2017 Jun 2.


Successful endoscopic fragmentation of large hardened fecaloma using jumbo forceps.

Matsuo Y, Yasuda H, Nakano H, Hattori M, Ozawa M, Sato Y, Ikeda Y, Ozawa SI, Yamashita M, Yamamoto H, Itoh F.

World J Gastrointest Endosc. 2017 Feb 16;9(2):91-94. doi: 10.4253/wjge.v9.i2.91.


Effects of vaccine-acquired polyclonal anti-HBs antibodies on the prevention of HBV infection of non-vaccine genotypes.

Kato M, Hamada-Tsutsumi S, Okuse C, Sakai A, Matsumoto N, Sato M, Sato T, Arito M, Omoteyama K, Suematsu N, Okamoto K, Kato T, Itoh F, Sumazaki R, Tanaka Y, Yotsuyanagi H, Kato T, Kurokawa MS.

J Gastroenterol. 2017 Sep;52(9):1051-1063. doi: 10.1007/s00535-017-1316-3. Epub 2017 Feb 14.


TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.

Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S.

J Biol Chem. 2017 Mar 10;292(10):4099-4112. doi: 10.1074/jbc.M116.769109. Epub 2017 Jan 23.


Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV-associated head and neck squamous cell carcinoma cell lines.

Hatano T, Sano D, Takahashi H, Hyakusoku H, Isono Y, Shimada S, Sawakuma K, Takada K, Oikawa R, Watanabe Y, Yamamoto H, Itoh F, Myers JN, Oridate N.

Int J Cancer. 2017 Apr 1;140(7):1571-1580. doi: 10.1002/ijc.30589. Epub 2017 Jan 9.


Crowned dens syndrome developed after an endoscopic retrograde cholangiopancreatography procedure.

Nakano H, Nakahara K, Michikawa Y, Suetani K, Morita R, Matsumoto N, Itoh F.

World J Gastroenterol. 2016 Oct 21;22(39):8849-8852.


Impact of resistance-associated variant dominancy on treatment in patients with HCV genotype 1b receiving daclatasvir/asunaprevir.

Ikeda H, Watanabe T, Okuse C, Matsumoto N, Ishii T, Yamada N, Shigefuku R, Hattori N, Matsunaga K, Nakano H, Hiraishi T, Kobayashi M, Yasuda K, Yamamoto H, Yasuda H, Kurosaki M, Izumi N, Yotsuyanagi H, Suzuki M, Itoh F.

J Med Virol. 2017 Jan;89(1):99-105. doi: 10.1002/jmv.24608. Epub 2016 Jul 6.


Successful treatment of three patients with human immunodeficiency virus and hepatitis C virus genotype 1b co-infection by daclatasvir plus asunaprevir.

Hirashima N, Iwase H, Shimada M, Ryuge N, Imamura J, Ikeda H, Tanaka Y, Matsumoto N, Okuse C, Itoh F, Yokomaku Y, Watanabe T.

Clin J Gastroenterol. 2017 Feb;10(1):41-46. doi: 10.1007/s12328-016-0693-0. Epub 2016 Oct 20.


Correlations of Hepatic Hemodynamics, Liver Function, and Fibrosis Markers in Nonalcoholic Fatty Liver Disease: Comparison with Chronic Hepatitis Related to Hepatitis C Virus.

Shigefuku R, Takahashi H, Nakano H, Watanabe T, Matsunaga K, Matsumoto N, Kato M, Morita R, Michikawa Y, Tamura T, Hiraishi T, Hattori N, Noguchi Y, Nakahara K, Ikeda H, Ishii T, Okuse C, Sase S, Itoh F, Suzuki M.

Int J Mol Sci. 2016 Sep 14;17(9). pii: E1545. doi: 10.3390/ijms17091545.


Twelve-year natural history of a gastric adenocarcinoma of fundic gland type.

Sato Y, Fujino T, Kasagawa A, Morita R, Ozawa SI, Matsuo Y, Maehata T, Yasuda H, Takagi M, Itoh F.

Clin J Gastroenterol. 2016 Dec;9(6):345-351. Epub 2016 Sep 13.


Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubility.

Nishizawa N, Takatsu Y, Kumano S, Kiba A, Ban J, Tsutsumi S, Matsui H, Matsumoto SI, Yamaguchi M, Ikeda Y, Kusaka M, Ohtaki T, Itoh F, Asami T.

J Med Chem. 2016 Oct 13;59(19):8804-8811. Epub 2016 Sep 21.


BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent Manner.

Yamamoto H, Watanabe Y, Oikawa R, Morita R, Yoshida Y, Maehata T, Yasuda H, Itoh F.

Clin Transl Gastroenterol. 2016 Jul 21;7(7):e184. doi: 10.1038/ctg.2016.40.


A case of Ménétrier's disease seemingly caused by hilar cholangiocarcinoma.

Sato N, Nakahara K, Morita R, Suetani K, Michikawa Y, Nakano H, Koizumi S, Otsubo T, Fujino T, Itoh F.

Nihon Shokakibyo Gakkai Zasshi. 2016;113(6):975-82. doi: 10.11405/nisshoshi.113.975. Japanese.


A case of gradually manifesting McCune-Albright syndrome with a 10-year follow-up.

Honda T, Itoh F, Nakamura K, Ohba T, Katabuchi H.

Reprod Med Biol. 2016 Apr 15;15(4):261-265. doi: 10.1007/s12522-016-0242-z. eCollection 2016 Oct.


Can the Abbott RealTime hepatitis C virus assay be used to predict therapeutic outcomes in hepatitis C virus-infected patients undergoing triple therapy?

Ikeda H, Okuse C, Watanabe T, Matsumoto N, Matsunaga K, Shigefuku R, Hattori N, Hiraishi T, Fukuda Y, Noguchi Y, Ishii T, Shima J, Nakahara K, Yamamoto H, Yasuda H, Yotsuyanagi H, Koike K, Itoh F, Suzuki M.

Turk J Gastroenterol. 2016 Mar;27(2):165-72. doi: 10.5152/tjg.2016.150300.


Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout.

Tatani K, Hiratochi M, Kikuchi N, Kuramochi Y, Watanabe S, Yamauchi Y, Itoh F, Isaji M, Shuto S.

J Med Chem. 2016 Apr 28;59(8):3719-31. doi: 10.1021/acs.jmedchem.5b01884. Epub 2016 Apr 11.


Hemoglobin Decrease with Iron Deficiency Induced by Daclatasvir plus Asunaprevir Combination Therapy for Chronic Hepatitis C Virus Genotype 1b.

Matsumoto N, Ikeda H, Shigefuku R, Hattori N, Watanabe T, Matsunaga K, Hiraishi T, Tamura T, Noguchi Y, Fukuda Y, Ishii T, Okuse C, Sato A, Suzuki M, Itoh F.

PLoS One. 2016 Mar 18;11(3):e0151238. doi: 10.1371/journal.pone.0151238. eCollection 2016.


A Novel Approach for Endoscopic Papillary Balloon Dilation with the Guidewire Left in the Pancreatic Duct to Ensure Pancreatic Stenting.

Nakahara K, Okuse C, Suetani K, Michikawa Y, Kobayasi S, Otsubo T, Itoh F.

Hepatogastroenterology. 2015 Jun;62(140):1027-31.


Endoscopic Double Metallic Stenting in the Afferent and Efferent Loops for Malignant Afferent Loop Obstruction with Billroth II Anatomy.

Nakahara K, Sato Y, Suetani K, Morita R, Michikawa Y, Kobayashi S, Itoh F.

Clin Endosc. 2016 Jan;49(1):97-9. doi: 10.5946/ce.2016.49.1.97. Epub 2016 Jan 28. No abstract available.


[Detection of early gastric cancer facilitated by surveillance for a pyogenic liver abscess caused by Streptococcus intermedius].

Shigefuku R, Matsunaga K, Tamura T, Ozawa S, Matsuo Y, Takahashi H, Matsumoto N, Okuse C, Suzuki M, Itoh F.

Nihon Shokakibyo Gakkai Zasshi. 2016;113(2):263-72. doi: 10.11405/nisshoshi.113.263. Review. Japanese.


Analysis of Helicobacter pylori genotypes in clinical gastric wash samples.

Miyamoto S, Watanabe Y, Oikawa R, Ono S, Mabe K, Kudo T, Yamamoto H, Itoh F, Kato M, Sakamoto N.

Tumour Biol. 2016 Aug;37(8):10123-32. doi: 10.1007/s13277-016-4886-4. Epub 2016 Jan 29.


Hemostasis Achieved Endoscopically for Diverticular Bleeding from the Horizontal Portion of the Duodenum.

Matuso Y, Yasuda H, Suzuki M, Ishigooka S, Ozawa S, Yamashita M, Yamamoto H, Itoh F.

Clin Med Insights Gastroenterol. 2015 Dec 6;8:61-4. doi: 10.4137/CGast.S32421. eCollection 2015.


The Safety and Anti-Tumor Effects of Ozonated Water in Vivo.

Kuroda K, Azuma K, Mori T, Kawamoto K, Murahata Y, Tsuka T, Osaki T, Ito N, Imagawa T, Itoh F, Okamoto Y.

Int J Mol Sci. 2015 Oct 22;16(10):25108-20. doi: 10.3390/ijms161025108.


Transforming growth factor-β signaling enhancement by long-term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells.

Furuta C, Miyamoto T, Takagi T, Noguchi Y, Kaneko J, Itoh S, Watanabe T, Itoh F.

Cancer Sci. 2015 Nov;106(11):1524-33. doi: 10.1111/cas.12773. Epub 2015 Oct 14.

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