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Drug Utilization Patterns in Patients with Diabetes Initiating Sodium Glucose Co-Transporter-2 Inhibitors (SGLT2i) in Japan: A Multi-Database Study (2014-2017).

Ito Y, Van Schyndle J, Nishimura T, Sugitani T, Kimura T.

Diabetes Ther. 2019 Oct 18. doi: 10.1007/s13300-019-00710-2. [Epub ahead of print]


Real-World Effectiveness of Sodium Glucose Co-Transporter-2 Inhibitors in Japanese Patients with Diabetes Mellitus.

Ito Y, Van Schyndle J, Nishimura T, Sugitani T, Kimura T.

Diabetes Ther. 2019 Oct 15. doi: 10.1007/s13300-019-00708-w. [Epub ahead of print]


Reactivity Control of Polymer Functional Groups by Altering the Structure of Thermoresponsive Triblock Copolymers.

Akimoto J, Tamate R, Okazawa S, Akimoto AM, Onoda M, Yoshida R, Ito Y.

ACS Omega. 2019 Sep 24;4(15):16344-16351. doi: 10.1021/acsomega.9b01816. eCollection 2019 Oct 8.


Single-arm confirmatory trial of postoperative concurrent chemoradiotherapy using intensity modulated radiation therapy for patients with high-risk uterine cervical cancer: Japan Clinical Oncology Group study (JCOG1402).

Murakami N, Isohashi F, Hasumi Y, Kasamatsu T, Okamoto H, Nakamura K, Shibata T, Ito Y, Ishikura S, Nishimura Y, Yaegashi N, Toita T.

Jpn J Clin Oncol. 2019 Sep 1;49(9):881-885. doi: 10.1093/jjco/hyz098.


Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130).

Iwata H, Inoue K, Kaneko K, Ito Y, Tsugawa K, Hasegawa A, Nakagawa S, Kuratomi H, Tamura K.

Jpn J Clin Oncol. 2019 Oct 15. pii: hyz135. doi: 10.1093/jjco/hyz135. [Epub ahead of print]


Intestinal flow after anastomotic operations in neonates.

Ito Y, Asato K, Cho I, Sakai Y, Iwano K, Tainaka T, Uchida H.

Comput Biol Med. 2019 Oct 11:103471. doi: 10.1016/j.compbiomed.2019.103471. [Epub ahead of print]


GABAB Receptor Signaling in the Mesolimbic System Suppresses Binge-like Consumption of a High-Fat Diet.

Tsunekawa T, Banno R, Yaginuma H, Taki K, Mizoguchi A, Sugiyama M, Onoue T, Takagi H, Hagiwara D, Ito Y, Iwama S, Goto M, Suga H, Bettler B, Arima H.

iScience. 2019 Sep 26;20:337-347. doi: 10.1016/j.isci.2019.09.032. [Epub ahead of print]


Safety of Ipragliflozin in Patients with Type 2 Diabetes Mellitus: Pooled Analysis of Phase II/III/IV Clinical Trials.

Kashiwagi A, Shestakova MV, Ito Y, Noguchi M, Wilpshaar W, Yoshida S, Wilding JPH.

Diabetes Ther. 2019 Oct 12. doi: 10.1007/s13300-019-00699-8. [Epub ahead of print]


Prognostic Value of Extranodal Tumor Extension in Papillary Thyroid Carcinoma: Proposal for Upstaging of Cases with Extranodal Tumor Extension.

Ito Y, Miyauchi A, Masuoka H, Higashiyama T, Kihara M, Miya A.

World J Surg. 2019 Oct 11. doi: 10.1007/s00268-019-05232-3. [Epub ahead of print]


α-Aminoisobutyric acid-containing amphipathic helical peptide-cyclic RGD conjugation as a potential drug delivery system for microRNA replacement therapy in vitro.

Taniguchi K, Wada SI, Ito Y, Hayashi J, Inomata Y, Lee SW, Tanaka T, Komura K, Akao Y, Urata H, Uchiyama K.

Mol Pharm. 2019 Oct 9. doi: 10.1021/acs.molpharmaceut.9b00680. [Epub ahead of print]


Cytoplasmic fusion between an enlarged embryonic stem cell and a somatic cell using a microtunnel device.

Kim SM, Wada KI, Ueki M, Hosokawa K, Maeda M, Sakai Y, Ito Y.

Biochem Biophys Res Commun. 2019 Oct 5. pii: S0006-291X(19)31869-8. doi: 10.1016/j.bbrc.2019.09.131. [Epub ahead of print]


Analysis of the prevalence of systemic de novo thrombotic microangiopathy after ABO-incompatible kidney transplantation and the associated risk factors.

Tasaki M, Saito K, Nakagawa Y, Imai N, Ito Y, Yoshida Y, Ikeda M, Ishikawa S, Narita I, Takahashi K, Tomita Y.

Int J Urol. 2019 Oct 6. doi: 10.1111/iju.14118. [Epub ahead of print]


Leucine-Rich Alpha-2-Glycoprotein 1 in Serum Is a Possible Biomarker to Predict Response to Preoperative Chemoradiotherapy for Esophageal Cancer.

Nambu M, Masuda T, Ito S, Kato K, Kojima T, Daiko H, Ito Y, Honda K, Ohtsuki S.

Biol Pharm Bull. 2019;42(10):1766-1771. doi: 10.1248/bpb.b19-00395.


Skin ligation and argon beam coagulation for giant pachydermatocele resection.

Morita D, Nemoto H, Togo T, Kimura N, Ito Y.

J Surg Case Rep. 2019 Sep 25;2019(9):rjz264. doi: 10.1093/jscr/rjz264. eCollection 2019 Sep.


Ileal conduit necrosis after total pelvic exenteration for recurrence of gastrointestinal stromal tumor.

Komori K, Okuno N, Kinoshita T, Oshiro T, Ouchi A, Ito S, Abe T, Senda Y, Misawa K, Ito Y, Uemura N, Natsume S, Higaki E, Okuno M, Hosoi T, An B, Hayashi D, Uchino T, Kunitomo A, Oki S, Takano J, Suenaga Y, Maeda S, Dei H, Numata Y, Shimizu Y.

Nagoya J Med Sci. 2019 Aug;81(3):529-534. doi: 10.18999/nagjms.81.3.529.


Tegafur and 5-fluorouracil levels in tears and changes in tear volume in long-term users of the oral anticancer drug S-1.

Kuriki R, Hata T, Nakayama K, Ito Y, Misawa K, Ito S, Tatematsu M, Kaneda N.

Nagoya J Med Sci. 2019 Aug;81(3):415-425. doi: 10.18999/nagjms.81.3.415.


Randomized clinical trial of extensive intraoperative peritoneal lavage versus standard treatment for resectable advanced gastric cancer (CCOG 1102 trial).

Misawa K, Mochizuki Y, Sakai M, Teramoto H, Morimoto D, Nakayama H, Tanaka N, Matsui T, Ito Y, Ito S, Tanaka K, Uemura K, Morita S, Kodera Y; Chubu Clinical Oncology Group.

Br J Surg. 2019 Oct 1. doi: 10.1002/bjs.11303. [Epub ahead of print]


Micropatterned nanolayers immobilized with nerve growth factor for neurite formation of PC12 cells.

Kim SM, Ueki M, Ren X, Akimoto J, Sakai Y, Ito Y.

Int J Nanomedicine. 2019 Sep 19;14:7683-7694. doi: 10.2147/IJN.S217416. eCollection 2019.


Synthesis of 2'-C,4'-C-Methyleneoxy-Bridged Thymidine Derivatives and Properties of Modified Oligonucleotides.

Osawa T, Kim H, Shoji M, Saijo M, Dohi M, Ito Y, Obika S, Hari Y.

J Org Chem. 2019 Oct 10. doi: 10.1021/acs.joc.9b01496. [Epub ahead of print]


[Cognitive Dysfunction in Children who Underwent Surgery after a Traumatic Brain Injury:A Single Institute Investigation].

Goto M, Ito Y, Tsukada K, Nakamura K, Uemura K, Ishikawa E, Matsumura A.

No Shinkei Geka. 2019 Sep;47(9):949-956. doi: 10.11477/mf.1436204053. Japanese.


Identification of recombinant AtPYL2, an abscisic acid receptor, in E. coli using a substrate-derived bioactive small molecule, a biotin linker with alkyne and amino groups, and a protein cross-linker.

Anabuki T, Ito Y, Ohashi K, Takasuka TE, Matsuura H, Takahashi K.

Bioorg Med Chem Lett. 2019 Nov 1;29(21):126634. doi: 10.1016/j.bmcl.2019.126634. Epub 2019 Aug 21.


Clinical Impact and Predictors of the Slow-Flow Phenomenon after Endovascular Treatment of Infrapopliteal Lesions Using the Crosser Catheter in Patients with Critical Limb Ischemia.

Kobayashi N, Hirano K, Yamawaki M, Araki M, Sakai T, Sakamoto Y, Mori S, Tsutsumi M, Nauchi M, Honda Y, Makino K, Shirai S, Sugizaki Y, Fukagawa T, Kishida T, Ito Y.

J Vasc Interv Radiol. 2019 Sep 18. pii: S1051-0443(19)30548-2. doi: 10.1016/j.jvir.2019.05.034. [Epub ahead of print]


Improved methods for the differentiation of hypothalamic vasopressin neurons using mouse induced pluripotent stem cells.

Mitsumoto K, Suga H, Sakakibara M, Soen M, Yamada T, Ozaki H, Nagai T, Kano M, Kasai T, Ozone C, Ogawa K, Sugiyama M, Onoue T, Tsunekawa T, Takagi H, Hagiwara D, Ito Y, Iwama S, Goto M, Banno R, Arima H.

Stem Cell Res. 2019 Sep 6;40:101572. doi: 10.1016/j.scr.2019.101572. [Epub ahead of print]


Impact of advanced maternal age on adverse infant outcomes: A Japanese population-based study.

Koshida S, Arima H, Fujii T, Ito Y, Murakami T, Takahashi K.

Eur J Obstet Gynecol Reprod Biol. 2019 Aug 23. pii: S0301-2115(19)30390-2. doi: 10.1016/j.ejogrb.2019.08.011. [Epub ahead of print]


Tubular Network Formation by Mixing Amphiphilic Polypeptides with Differing Hydrophilic Blocks.

Rahman MM, Ueda M, Son K, Seo S, Takeoka S, Hirose T, Ito Y.

Biomacromolecules. 2019 Oct 14;20(10):3908-3914. doi: 10.1021/acs.biomac.9b00986. Epub 2019 Sep 30.


Construction of Pyrimidine Bases Bearing Carboxylic Acid Equivalents at the C5 Position by Postsynthetic Modification of Oligonucleotides.

Ito Y, Yamamoto K, Hari Y.

Curr Protoc Nucleic Acid Chem. 2019 Sep;78(1):e91. doi: 10.1002/cpnc.91.


ABCC11 gene polymorphism as a potential predictive biomarker for an oral 5-fluorouracil derivative drug S-1 treatment in non-small cell lung cancer.

Uemura T, Oguri T, Maeno K, Sone K, Takeuchi A, Fukuda S, Kunii E, Takakuwa O, Kanemitsu Y, Ohkubo H, Takemura M, Ito Y, Niimi A.

Cancer Chemother Pharmacol. 2019 Sep 17. doi: 10.1007/s00280-019-03959-3. [Epub ahead of print]


Kinetics-Based Structural Requirements of Human Immunoglobulin G Binding Peptides.

Muguruma K, Fujita K, Fukuda A, Kishimoto S, Sakamoto S, Arima R, Ito M, Kawasaki M, Nakano S, Ito S, Shimizu K, Taguchi A, Takayama K, Taniguchi A, Ito Y, Hayashi Y.

ACS Omega. 2019 Aug 28;4(11):14390-14397. doi: 10.1021/acsomega.9b01104. eCollection 2019 Sep 10.


Probing gaseous molecular structure by molecular-frame photoelectron angular distributions.

Fukuzawa H, Yamada S, Sakakibara Y, Tachibana T, Ito Y, Takanashi T, Nishiyama T, Sakai T, Nagaya K, Saito N, Oura M, Stener M, Decleva P, Ueda K.

J Chem Phys. 2019 Sep 14;151(10):104302. doi: 10.1063/1.5115801.


Antimicrobial and antibiofilm effects of abietic acid on cariogenic Streptococcus mutans.

Ito Y, Ito T, Yamashiro K, Mineshiba F, Hirai K, Omori K, Yamamoto T, Takashiba S.

Odontology. 2019 Sep 13. doi: 10.1007/s10266-019-00456-0. [Epub ahead of print]


Surgical Strategy for Rectovaginal Fistula After Colorectal Anastomosis at a High-volume Cancer Center According to Image Type and Colonoscopy Findings.

Komori K, Kinoshita T, Oshiro T, Ouchi A, Ito S, Abe T, Senda Y, Misawa K, Ito Y, Natsume S, Higaki E, Okuno M, Hosoi T, Nagao T, Kunitomo A, Oki S, Takano J, Suenaga Y, Maeda S, Dei H, Numata Y, Shimizu Y.

Anticancer Res. 2019 Sep;39(9):5097-5103. doi: 10.21873/anticanres.13704.


Cheek-splitting technique for marginal mandibulectomy: A novel approach.

Abe A, Kurita K, Hayashi H, Ito Y.

J Clin Exp Dent. 2019 Jul 1;11(7):e675-e678. doi: 10.4317/jced.55872. eCollection 2019 Jul.


Needle Tract Implantation Following Fine-Needle Aspiration of Thyroid Cancer.

Hayashi T, Hirokawa M, Higuchi M, Kudo T, Ito Y, Miyauchi A.

World J Surg. 2019 Sep 12. doi: 10.1007/s00268-019-05161-1. [Epub ahead of print]


Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement.

Okamoto M, Ali M, Komichi S, Watanabe M, Huang H, Ito Y, Miura J, Hirose Y, Mizuhira M, Takahashi Y, Okuzaki D, Kawabata S, Imazato S, Hayashi M.

J Clin Med. 2019 Sep 11;8(9). pii: E1440. doi: 10.3390/jcm8091440.


Magnetic Resonance Imaging Findings Following Ceramic-on-Ceramic Total Hip Arthroplasty Using Modular Neck Femoral Components.

Takigami I, Ito Y, Miyagawa T, Akiyama H.

Bull Hosp Jt Dis (2013). 2018 Sep;76(3):171-175.


Light-inducible carotenoid production controlled by a MarR-type regulator in Corynebacterium glutamicum.

Sumi S, Suzuki Y, Matsuki T, Yamamoto T, Tsuruta Y, Mise K, Kawamura T, Ito Y, Shimada Y, Watanabe E, Watanabe S, Toriyabe M, Takano Shiratori H, Ueda K, Takano H.

Sci Rep. 2019 Sep 11;9(1):13136. doi: 10.1038/s41598-019-49384-7.


Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state.

Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A.

Int J Cancer. 2019 Sep 10. doi: 10.1002/ijc.32672. [Epub ahead of print]


Novel Method for Rapid Assessment of Cognitive Impairment Using High-Performance Eye-Tracking Technology.

Oyama A, Takeda S, Ito Y, Nakajima T, Takami Y, Takeya Y, Yamamoto K, Sugimoto K, Shimizu H, Shimamura M, Katayama T, Rakugi H, Morishita R.

Sci Rep. 2019 Sep 10;9(1):12932. doi: 10.1038/s41598-019-49275-x.


Metagenomic analysis using next-generation sequencing of pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure.

Takeuchi S, Kawada JI, Horiba K, Okuno Y, Okumura T, Suzuki T, Torii Y, Kawabe S, Wada S, Ikeyama T, Ito Y.

Sci Rep. 2019 Sep 9;9(1):12909. doi: 10.1038/s41598-019-49372-x.


Author Correction: Domestic cats (Felis catus) discriminate their names from other words.

Saito A, Shinozuka K, Ito Y, Hasegawa T.

Sci Rep. 2019 Sep 10;9(1):13265. doi: 10.1038/s41598-019-46257-x.


Effect of denture adhesives on oral moisture: A multicenter randomized controlled trial.

Nishi Y, Nomura T, Murakami M, Kawai Y, Nishimura M, Kondo H, Ito Y, Tsuboi A, Hong G, Kimoto S, Gunji A, Suzuki A, Ohwada G, Minakuchi S, Sato Y, Suzuki T, Kimoto K, Hoshi N, Saita M, Yoneyama Y, Sato Y, Morokuma M, Okazaki J, Maeda T, Nakai K, Ichikawa T, Nagao K, Fujimoto K, Murata H, Kurogi T, Yoshida K, Hosoi T, Hamada T.

J Prosthodont Res. 2019 Sep 6. pii: S1883-1958(19)30311-1. doi: 10.1016/j.jpor.2019.08.004. [Epub ahead of print]


Pseudo-sawtooth pattern on amplitude-integrated electroencephalography in neonatal hypoxic-ischemic encephalopathy.

Tanaka M, Kidokoro H, Kubota T, Fukasawa T, Okai Y, Sakaguchi Y, Ito Y, Yamamoto H, Ohno A, Nakata T, Negoro T, Okumura A, Kato T, Watanabe K, Takahashi Y, Natsume J.

Pediatr Res. 2019 Sep 7. doi: 10.1038/s41390-019-0567-5. [Epub ahead of print]


Prognosis After Laparoscopic Gastrectomy in Patients with Pathological Stage II or III Gastric Cancer Who Were Preoperatively Diagnosed with Clinical Stage I: Propensity Score Matching Analysis of a Multicenter Dataset.

Ito Y, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y.

Ann Surg Oncol. 2019 Sep 6. doi: 10.1245/s10434-019-07781-2. [Epub ahead of print]


Amplicon Sequencing-Based Noninvasive Fetal Genotyping for RHD-Positive D Antigen-Negative Alleles.

Takahashi K, Migita O, Sasaki A, Nasu M, Kawashima A, Sekizawa A, Sato T, Ito Y, Sago H, Okamoto A, Nakabayashi K, Hata K.

Clin Chem. 2019 Oct;65(10):1307-1316. doi: 10.1373/clinchem.2019.307074. Epub 2019 Sep 5.


Risk Factors for Post-Endoscopic Retrograde Pancreatography Pancreatitis: A Retrospective Chart Review in a Regional Hospital in Japan.

Shimamura T, Miyahara K, Takamori A, Hidaka H, Ito Y, Fujimoto S, Takedomi H, Tsuruoka N, Sakata Y, Eguchi Y, Node K, Noda T, Fujimoto K.

Digestion. 2019 Sep 5:1-6. doi: 10.1159/000501309. [Epub ahead of print] Review.


Effects of Domperidone in Increasing Milk Production in Mothers with Insufficient Lactation for Infants in the Neonatal Intensive Care Unit.

Wada Y, Suyama F, Sasaki A, Saito J, Shimizu Y, Amari S, Ito Y, Sago H.

Breastfeed Med. 2019 Sep 4. doi: 10.1089/bfm.2019.0111. [Epub ahead of print]


Thiocyanation of Aromatic and Heteroaromatic Compounds with 1-Chloro-1,2-benziodoxol-3-(1H)-one and (Trimethylsilyl)isothiocyanate.

Ito Y, Touyama A, Uku M, Egami H, Hamashima Y.

Chem Pharm Bull (Tokyo). 2019;67(9):1015-1018. doi: 10.1248/cpb.c19-00352.


Thromboxane A2 receptor signaling in endothelial cells attenuates monocrotaline-induced liver injury.

Otaka F, Ito Y, Inoue T, Ohkubo H, Nishizawa N, Kojo K, Betto T, Yamane S, Narumiya S, Koizumi W, Majima M.

Toxicol Appl Pharmacol. 2019 Oct 15;381:114733. doi: 10.1016/j.taap.2019.114733. Epub 2019 Aug 27.


Two Birds with One Stone: Spontaneous Size Separation and Growth Inhibition of Femtosecond Laser-Generated Surfactant-Free Metallic Nanoparticles via ex Situ SU-8 Functionalization.

Zhang D, Choi W, Yazawa K, Numata K, Tateishi A, Cho SH, Lin HP, Li YK, Ito Y, Sugioka K.

ACS Omega. 2018 Sep 11;3(9):10953-10966. doi: 10.1021/acsomega.8b01250. eCollection 2018 Sep 30.


Improved home BP profile with dapagliflozin is associated with amelioration of albuminuria in Japanese patients with diabetic nephropathy: the Yokohama add-on inhibitory efficacy of dapagliflozin on albuminuria in Japanese patients with type 2 diabetes study (Y-AIDA study).

Kinguchi S, Wakui H, Ito Y, Kondo Y, Azushima K, Osada U, Yamakawa T, Iwamoto T, Yutoh J, Misumi T, Aoki K, Yasuda G, Yoshii T, Yamada T, Ono S, Shibasaki-Kurita T, Hosokawa S, Orime K, Hanaoka M, Sasaki H, Inazumi K, Yamada T, Kobayashi R, Ohki K, Haruhara K, Kobayashi Y, Yamanaka T, Terauchi Y, Tamura K.

Cardiovasc Diabetol. 2019 Aug 27;18(1):110. doi: 10.1186/s12933-019-0912-3.

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