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Items: 42

1.

[Successful treatment with chloramphenicol in four pediatric cases of intractable bacterial meningitis].

Morita K, Abe Y, Itano A, Musha I, Koga T, Yamazaki T, Yamanouchi H.

No To Hattatsu. 2016 Jan;48(1):29-33. Japanese.

PMID:
27012107
2.

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.

Murray JK, Qian YX, Liu B, Elliott R, Aral J, Park C, Zhang X, Stenkilsson M, Salyers K, Rose M, Li H, Yu S, Andrews KL, Colombero A, Werner J, Gaida K, Sickmier EA, Miu P, Itano A, McGivern J, Gegg CV, Sullivan JK, Miranda LP.

J Med Chem. 2015 Sep 10;58(17):6784-802. doi: 10.1021/acs.jmedchem.5b00495. Epub 2015 Aug 31.

PMID:
26288216
3.

Usefulness of modified Pulmonary Index Score (mPIS) as a quantitative tool for the evaluation of severe acute exacerbation in asthmatic children.

Koga T, Tokuyama K, Itano A, Morita E, Ueda Y, Katsunuma T.

Allergol Int. 2015 Apr;64(2):139-44. doi: 10.1016/j.alit.2014.10.003. Epub 2014 Dec 1.

4.

3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models.

Soth M, Hermann JC, Yee C, Alam M, Barnett JW, Berry P, Browner MF, Frank K, Frauchiger S, Harris S, He Y, Hekmat-Nejad M, Hendricks T, Henningsen R, Hilgenkamp R, Ho H, Hoffman A, Hsu PY, Hu DQ, Itano A, Jaime-Figueroa S, Jahangir A, Jin S, Kuglstatter A, Kutach AK, Liao C, Lynch S, Menke J, Niu L, Patel V, Railkar A, Roy D, Shao A, Shaw D, Steiner S, Sun Y, Tan SL, Wang S, Vu MD.

J Med Chem. 2013 Jan 10;56(1):345-56. doi: 10.1021/jm301646k. Epub 2012 Dec 19.

PMID:
23214979
5.

Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.

Reed AB, Lanman BA, Neira S, Harrington PE, Sham KK, Frohn M, Pickrell AJ, Tasker AS, Gore A, Fiorino M, Itano A, McElvain M, Middleton S, Morrison H, Xu H, Xu Y, Wong M, Cee VJ.

Bioorg Med Chem Lett. 2012 Feb 15;22(4):1779-83. doi: 10.1016/j.bmcl.2011.12.073. Epub 2011 Dec 21.

PMID:
22257889
6.

Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5.

Cee VJ, Frohn M, Lanman BA, Golden J, Muller K, Neira S, Pickrell A, Arnett H, Buys J, Gore A, Fiorino M, Horner M, Itano A, Lee MR, McElvain M, Middleton S, Schrag M, Rivenzon-Segal D, Vargas HM, Xu H, Xu Y, Zhang X, Siu J, Wong M, Bürli RW.

ACS Med Chem Lett. 2010 Dec 29;2(2):107-12. doi: 10.1021/ml100306h. eCollection 2011 Feb 10.

7.

Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1).

Lanman BA, Cee VJ, Cheruku SR, Frohn M, Golden J, Lin J, Lobera M, Marantz Y, Muller KM, Neira SC, Pickrell AJ, Rivenzon-Segal D, Schutz N, Sharadendu A, Yu X, Zhang Z, Buys J, Fiorino M, Gore A, Horner M, Itano A, McElvain M, Middleton S, Schrag M, Vargas HM, Xu H, Xu Y, Zhang X, Siu J, Bürli RW.

ACS Med Chem Lett. 2010 Nov 9;2(2):102-6. doi: 10.1021/ml100228m. eCollection 2011 Feb 10.

8.

Mechanistic medicine: novel strategies for clinical trials.

Itano AA, Sims MJ, Siu G.

Autoimmunity. 2010 Nov;43(7):560-71. doi: 10.3109/08916931003674782. Epub 2010 Apr 30. Review.

PMID:
20429849
9.

Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses.

Larson RP, Zimmerli SC, Comeau MR, Itano A, Omori M, Iseki M, Hauser C, Ziegler SF.

J Immunol. 2010 Mar 15;184(6):2974-84. doi: 10.4049/jimmunol.0803478. Epub 2010 Feb 19.

10.

Neonatal death in mice lacking cardiotrophin-like cytokine is associated with multifocal neuronal hypoplasia.

Zou X, Bolon B, Pretorius JK, Kurahara C, McCabe J, Christiansen KA, Sun N, Duryea D, Foreman O, Senaldi G, Itano AA, Siu G.

Vet Pathol. 2009 May;46(3):514-9. doi: 10.1354/vp.08-VP-0239-B-BC. Epub 2008 Dec 19.

PMID:
19098279
11.

Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds.

Zoog SJ, Itano A, Trueblood E, Pacheco E, Zhou L, Zhang X, Ferbas J, Ng GY, Juan G.

Cytometry A. 2009 Mar;75(3):189-98. doi: 10.1002/cyto.a.20658.

12.

Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases.

Chen N, Bürli RW, Neira S, Hungate R, Zhang D, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Meagher KL, Lee MR, Zhang X, Itano A, Schrag M, Xu Y, Ng GY, Hu E.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):4137-41. doi: 10.1016/j.bmcl.2008.05.089. Epub 2008 May 28.

PMID:
18554909
13.

Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit.

Hu E, Tasker A, White RD, Kunz RK, Human J, Chen N, Bürli R, Hungate R, Novak P, Itano A, Zhang X, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Xu Y, Meagher KL, Whittington DA, Ng GY.

J Med Chem. 2008 Jun 12;51(11):3065-8. doi: 10.1021/jm800188g. Epub 2008 May 1.

PMID:
18447379
14.

CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection.

Ravindran R, Rusch L, Itano A, Jenkins MK, McSorley SJ.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12075-80. Epub 2007 Jul 5.

15.

The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.

Pape KA, Catron DM, Itano AA, Jenkins MK.

Immunity. 2007 Apr;26(4):491-502. Epub 2007 Mar 22.

16.

CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells.

Catron DM, Rusch LK, Hataye J, Itano AA, Jenkins MK.

J Exp Med. 2006 Apr 17;203(4):1045-54. Epub 2006 Mar 27.

17.

Visualizing the first 50 hr of the primary immune response to a soluble antigen.

Catron DM, Itano AA, Pape KA, Mueller DL, Jenkins MK.

Immunity. 2004 Sep;21(3):341-7. Review.

19.

Antigen presentation to naive CD4 T cells in the lymph node.

Itano AA, Jenkins MK.

Nat Immunol. 2003 Aug;4(8):733-9. Review.

PMID:
12888794
20.

Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity.

Itano AA, McSorley SJ, Reinhardt RL, Ehst BD, Ingulli E, Rudensky AY, Jenkins MK.

Immunity. 2003 Jul;19(1):47-57.

21.

In vivo activation of antigen-specific CD4 T cells.

Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA.

Annu Rev Immunol. 2001;19:23-45. Review.

PMID:
11244029
23.

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

Irie HY, Mong MS, Itano A, Crooks ME, Littman DR, Burakoff SJ, Robey E.

J Immunol. 1998 Jul 1;161(1):183-91.

24.

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages.

Robey E, Chang D, Itano A, Cado D, Alexander H, Lans D, Weinmaster G, Salmon P.

Cell. 1996 Nov 1;87(3):483-92.

25.

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.

Itano A, Salmon P, Kioussis D, Tolaini M, Corbella P, Robey E.

J Exp Med. 1996 Mar 1;183(3):731-41.

26.

A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection.

Itano A, Cado D, Chan FK, Robey E.

Immunity. 1994 Jul;1(4):287-90.

PMID:
7889416
27.

Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity.

Corbella P, Moskophidis D, Spanopoulou E, Mamalaki C, Tolaini M, Itano A, Lans D, Baltimore D, Robey E, Kioussis D.

Immunity. 1994 Jul;1(4):269-76.

PMID:
7889414
28.
29.

Stochastic component to development of class I major histocompatibility complex-specific T cells.

Itano A, Kioussis D, Robey E.

Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):220-4.

30.

An outer surface protein is a major T cell antigen in experimental Lyme disease in CB6F1 mice.

Pachner AR, Itano A, Ricalton N.

Ann N Y Acad Sci. 1991 Dec 30;636:393-5. No abstract available.

PMID:
1793226
31.

Acetylcholine receptor-reactive T cells in murine experimental myasthenia react to all subunits of the receptor.

Pachner AR, Itano A, Ricalton N.

Ann N Y Acad Sci. 1991 Dec 30;636:390-2. No abstract available.

PMID:
1793225
32.

Chronic murine experimental myasthenia gravis: strength testing and serology.

Pachner AR, Itano A, Ricalton N, Choe S.

Clin Immunol Immunopathol. 1991 Jun;59(3):398-406.

PMID:
2029792
33.

Olfactory classical conditioning in neonates.

Sullivan RM, Taborsky-Barba S, Mendoza R, Itano A, Leon M, Cotman CW, Payne TF, Lott I.

Pediatrics. 1991 Apr;87(4):511-8.

34.
36.

Measurement of the reaction K+n

de Lesquen A, van Rossum L, Svec M, Babou M, Bystricky J, Cozzika G, Dobrowolski T, Ducros Y, Fujisaki M, Gaidot A, Hwang CF, Itano A, Khantine-Langlois F, Lehar F.

Phys Rev D Part Fields. 1989 Jan 1;39(1):21-44. No abstract available.

PMID:
9959472
37.

Evidence for two pseudoscalar resonances of eta pi + pi - system in the D(1285) and E/ iota regions.

Ando A, Imai K, Inaba S, Inagaki T, Inagaki Y, Itano A, Kobayashi S, Maruyama K, Murakami A, Nakamura T, Ohmi K, Okuno H, Sasaki A, Sato T, Shirai J, Takamatsu K, Takashima R, Tamura N, Tsuru T, Yasu Y.

Phys Rev Lett. 1986 Sep 15;57(11):1296-1299. No abstract available.

PMID:
10033409
38.

Measurement of the reaction pi +n

de Lesquen A, van Rossum L, Svec M, Babou M, Bystricky J, Cozzika G, Dobrowolski T, Ducros Y, Fujisaki M, Gaidot A, Hwang CF, Itano A, Khantine-Langlois F, Lehar F.

Phys Rev D Part Fields. 1985 Jul 1;32(1):21-34. No abstract available.

PMID:
9955983
39.

BIOLOGICAL INVESTIGATION OF PEAT.

Itano A.

J Bacteriol. 1925 Jan;10(1):87-95. No abstract available.

40.

Physiological Study of Azotobacter Chroococcum, Beijerinckii and Vinelandii Types.

Yamagata U, Itano A.

J Bacteriol. 1923 Nov;8(6):521-31. No abstract available.

41.
42.

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