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Items: 1 to 50 of 87

1.

Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.

Puca L, Gavyert K, Sailer V, Conteduca V, Dardenne E, Sigouros M, Isse K, Kearney M, Vosoughi A, Fernandez L, Pan H, Motanagh S, Hess J, Donoghue AJ, Sboner A, Wang Y, Dittamore R, Rickman D, Nanus DM, Tagawa ST, Elemento O, Mosquera JM, Saunders L, Beltran H.

Sci Transl Med. 2019 Mar 20;11(484). pii: eaav0891. doi: 10.1126/scitranslmed.aav0891.

2.

Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma.

Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, Riina HA, Nicolaides TP, Sulman EP, Cahill DP, Golfinos JG, Isse K, Saunders LR, Zagzag D, Placantonakis DG, Snuderl M, Chi AS.

Clin Cancer Res. 2019 Feb 15;25(4):1261-1271. doi: 10.1158/1078-0432.CCR-18-2312. Epub 2018 Nov 5.

PMID:
30397180
3.

Transcriptomic and Protein Analysis of Small-cell Bladder Cancer (SCBC) Identifies Prognostic Biomarkers and DLL3 as a Relevant Therapeutic Target.

Koshkin VS, Garcia JA, Reynolds J, Elson P, Magi-Galluzzi C, McKenney JK, Isse K, Bishop E, Saunders LR, Balyimez A, Rashid S, Hu M, Stephenson AJ, Fergany AF, Lee BH, Haber GP, Dowlati A, Gilligan T, Ornstein MC, Rini BI, Abazeed ME, Mian OY, Grivas P.

Clin Cancer Res. 2019 Jan 1;25(1):210-221. doi: 10.1158/1078-0432.CCR-18-1278. Epub 2018 Oct 16.

PMID:
30327311
4.

Isolated vascular "v" lesions in liver allografts: How to approach this unusual finding.

Stevenson HL, Prats MM, Isse K, Zeevi A, Avitzur Y, Ng VL, Demetris AJ.

Am J Transplant. 2018 Jun;18(6):1534-1543. doi: 10.1111/ajt.14708. Epub 2018 Mar 30.

5.

Prevalence of Delta-like protein 3 expression in patients with small cell lung cancer.

Tanaka K, Isse K, Fujihira T, Takenoyama M, Saunders L, Bheddah S, Nakanishi Y, Okamoto I.

Lung Cancer. 2018 Jan;115:116-120. doi: 10.1016/j.lungcan.2017.11.018. Epub 2017 Nov 22.

PMID:
29290251
6.

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.

Sharma SK, Pourat J, Abdel-Atti D, Carlin SD, Piersigilli A, Bankovich AJ, Gardner EE, Hamdy O, Isse K, Bheddah S, Sandoval J, Cunanan KM, Johansen EB, Allaj V, Sisodiya V, Liu D, Zeglis BM, Rudin CM, Dylla SJ, Poirier JT, Lewis JS.

Cancer Res. 2017 Jul 15;77(14):3931-3941. doi: 10.1158/0008-5472.CAN-17-0299. Epub 2017 May 9.

7.

Elevated ST2 Distinguishes Incidences of Pediatric Heart and Small Bowel Transplant Rejection.

Mathews LR, Lott JM, Isse K, Lesniak A, Landsittel D, Demetris AJ, Sun Y, Mercer DF, Webber SA, Zeevi A, Fischer RT, Feingold B, Turnquist HR.

Am J Transplant. 2016 Mar;16(3):938-50. doi: 10.1111/ajt.13542. Epub 2015 Dec 11.

8.

Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1.

Kang LI, Isse K, Koral K, Bowen WC, Muratoglu S, Strickland DK, Michalopoulos GK, Mars WM.

Lab Invest. 2015 Oct;95(10):1117-29. doi: 10.1038/labinvest.2015.94. Epub 2015 Aug 3.

9.

IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production.

Yokota S, Yoshida O, Dou L, Spadaro AV, Isse K, Ross MA, Stolz DB, Kimura S, Du Q, Demetris AJ, Thomson AW, Geller DA.

J Immunol. 2015 Jun 15;194(12):6045-56. doi: 10.4049/jimmunol.1402505. Epub 2015 May 11.

10.

A novel dual ex vivo lung perfusion technique improves immediate outcomes in an experimental model of lung transplantation.

Tanaka Y, Noda K, Isse K, Tobita K, Maniwa Y, Bhama JK, D'Cunha J, Bermudez CA, Luketich JD, Shigemura N.

Am J Transplant. 2015 May;15(5):1219-30. doi: 10.1111/ajt.13109. Epub 2015 Mar 16.

11.

Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia.

Mizuguchi Y, Specht S, Isse K, Sasatomi E, Lunz JG 3rd, Takizawa T, Demetris AJ.

J Hepatol. 2015 Aug;63(2):399-407. doi: 10.1016/j.jhep.2015.02.047. Epub 2015 Mar 12.

PMID:
25770659
12.

CD39 deficiency in murine liver allografts promotes inflammatory injury and immune-mediated rejection.

Yoshida O, Dou L, Kimura S, Yokota S, Isse K, Robson SC, Geller DA, Thomson AW.

Transpl Immunol. 2015 Mar;32(2):76-83. doi: 10.1016/j.trim.2015.01.003. Epub 2015 Feb 7.

13.

Inhibition of large T antigen ATPase activity as a potential strategy to develop anti-polyomavirus JC drugs.

Randhawa P, Zeng G, Bueno M, Salgarkar A, Lesniak A, Isse K, Seyb K, Perry A, Charles I, Hustus C, Huang M, Smith M, Glicksman MA.

Antiviral Res. 2014 Dec;112:113-9. doi: 10.1016/j.antiviral.2014.10.004. Epub 2014 Oct 15.

14.

Acute liver allograft antibody-mediated rejection: an inter-institutional study of significant histopathological features.

O'Leary JG, Michelle Shiller S, Bellamy C, Nalesnik MA, Kaneku H, Jennings LW, Isse K, Terasaki PI, Klintmalm GB, Demetris AJ.

Liver Transpl. 2014 Oct;20(10):1244-55. doi: 10.1002/lt.23948.

15.

Optimal lung inflation techniques in a rat lung transplantation model: a revisit.

Tanaka Y, Shigemura N, Noda K, Kawamura T, Isse K, Stolz DB, Bermudez CA.

Thorac Cardiovasc Surg. 2014 Aug;62(5):427-33. doi: 10.1055/s-0034-1373902. Epub 2014 May 1.

PMID:
24788707
16.

Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes.

Turner MS, Isse K, Fischer DK, Turnquist HR, Morel PA.

Diabetologia. 2014 Jul;57(7):1428-36. doi: 10.1007/s00125-014-3233-9. Epub 2014 Apr 16.

PMID:
24737163
17.

Distribution of non-gal antigens in pig cornea: relevance to corneal xenotransplantation.

Cohen D, Miyagawa Y, Mehra R, Lee W, Isse K, Long C, Ayares DL, Cooper DK, Hara H.

Cornea. 2014 Apr;33(4):390-7. doi: 10.1097/ICO.0000000000000069.

PMID:
24488129
18.

Increased soluble CD154 (CD40 ligand) levels in xenograft recipients correlate with the development of de novo anti-pig IgG antibodies.

Ezzelarab MB, Ekser B, Isse K, Iwase H, Morelli AE, Ayares D, Cooper DK.

Transplantation. 2014 Mar 15;97(5):502-8. doi: 10.1097/TP.0000000000000042.

PMID:
24487395
19.

Small proline rich protein 2a in benign and malignant liver disease.

Mizuguchi Y, Isse K, Specht S, Lunz JG 3rd, Corbitt N, Takizawa T, Demetris AJ.

Hepatology. 2014 Mar;59(3):1130-43. doi: 10.1002/hep.26889. Epub 2014 Jan 27.

PMID:
24123265
20.

"Plasma cell hepatitis" in liver allografts: identification and characterization of an IgG4-rich cohort.

Castillo-Rama M, Sebagh M, Sasatomi E, Randhawa P, Isse K, Salgarkar AD, Ruppert K, Humar A, Demetris AJ.

Am J Transplant. 2013 Nov;13(11):2966-77. doi: 10.1111/ajt.12413. Epub 2013 Sep 6.

21.

[Recommendations for ECT Practice, Second Edition].

Motohashi N, Awata S, Isse K, Ueda S, Okubo Y, Okumura M, Kashima H, Kawasaki H, Sameshima T, Sawa Y, Takebayashi M, Hatta K, Wakejima T, Wada K, Yamaguchi N, Yoneda H.

Seishin Shinkeigaku Zasshi. 2013;115(6):586-600. Review. Japanese. No abstract available.

PMID:
23944116
22.

SPRR2A expression in cholangiocarcinoma increases local tumor invasiveness but prevents metastasis.

Specht S, Isse K, Nozaki I, Lunz JG 3rd, Demetris AJ.

Clin Exp Metastasis. 2013 Oct;30(7):877-90. doi: 10.1007/s10585-013-9589-2. Epub 2013 Jun 1.

PMID:
23728799
23.

Tissue biopsy monitoring of operational tolerance in liver allograft recipients.

Demetris AJ, Isse K.

Curr Opin Organ Transplant. 2013 Jun;18(3):345-53. doi: 10.1097/MOT.0b013e3283615d48. Review.

PMID:
23619515
24.

Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status.

Hara H, Witt W, Crossley T, Long C, Isse K, Fan L, Phelps CJ, Ayares D, Cooper DK, Dai Y, Starzl TE.

Immunology. 2013 Sep;140(1):39-46. doi: 10.1111/imm.12107.

25.

Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation.

Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough BR, Lunz JG, Murase N, Yokota S, Demetris AJ.

Am J Pathol. 2013 Jan;182(1):180-91. doi: 10.1016/j.ajpath.2012.09.010. Epub 2012 Nov 14.

26.

Preexisting epithelial diversity in normal human livers: a tissue-tethered cytometric analysis in portal/periportal epithelial cells.

Isse K, Lesniak A, Grama K, Maier J, Specht S, Castillo-Rama M, Lunz J, Roysam B, Michalopoulos G, Demetris AJ.

Hepatology. 2013 Apr;57(4):1632-43. doi: 10.1002/hep.26131. Epub 2013 Mar 19.

27.

Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement.

Tanaka Y, Shigemura N, Kawamura T, Noda K, Isse K, Stolz DB, Billiar TR, Toyoda Y, Bermudez CA, Lyons-Weiler J, Nakao A.

Biochem Biophys Res Commun. 2012 Sep 7;425(4):873-9. doi: 10.1016/j.bbrc.2012.08.005. Epub 2012 Aug 7.

28.

STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia.

Poe SL, Arora M, Oriss TB, Yarlagadda M, Isse K, Khare A, Levy DE, Lee JS, Mallampalli RK, Chan YR, Ray A, Ray P.

Mucosal Immunol. 2013 Jan;6(1):189-99. doi: 10.1038/mi.2012.62. Epub 2012 Jul 11.

29.

SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity.

Mizuguchi Y, Specht S, Lunz JG 3rd, Isse K, Corbitt N, Takizawa T, Demetris AJ.

BMC Mol Biol. 2012 Jun 25;13:20. doi: 10.1186/1471-2199-13-20.

30.

Cooperation of p300 and PCAF in the control of microRNA 200c/141 transcription and epithelial characteristics.

Mizuguchi Y, Specht S, Lunz JG 3rd, Isse K, Corbitt N, Takizawa T, Demetris AJ.

PLoS One. 2012;7(2):e32449. doi: 10.1371/journal.pone.0032449. Epub 2012 Feb 22.

31.

Long-term effects of alemtuzumab on regulatory and memory T-cell subsets in kidney transplantation.

Macedo C, Walters JT, Orkis EA, Isse K, Elinoff BD, Fedorek SP, McMichael JM, Chalasani G, Randhawa P, Demetris AJ, Zeevi A, Tan H, Shapiro R, Landsittel D, Lakkis FG, Metes D.

Transplantation. 2012 Apr 27;93(8):813-21. doi: 10.1097/TP.0b013e318247a717.

32.

Digital transplantation pathology: combining whole slide imaging, multiplex staining and automated image analysis.

Isse K, Lesniak A, Grama K, Roysam B, Minervini MI, Demetris AJ.

Am J Transplant. 2012 Jan;12(1):27-37. doi: 10.1111/j.1600-6143.2011.03797.x. Epub 2011 Nov 4. Review.

33.

Re-examination of the lymphocytotoxic crossmatch in liver transplantation: can C4d stains help in monitoring?

Lunz J, Ruppert KM, Cajaiba MM, Isse K, Bentlejewski CA, Minervini M, Nalesnik MA, Randhawa P, Rubin E, Sasatomi E, de Vera ME, Fontes P, Humar A, Zeevi A, Demetris AJ.

Am J Transplant. 2012 Jan;12(1):171-82. doi: 10.1111/j.1600-6143.2011.03786.x. Epub 2011 Oct 12.

34.

IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

Turnquist HR, Zhao Z, Rosborough BR, Liu Q, Castellaneta A, Isse K, Wang Z, Lang M, Stolz DB, Zheng XX, Demetris AJ, Liew FY, Wood KJ, Thomson AW.

J Immunol. 2011 Nov 1;187(9):4598-610. doi: 10.4049/jimmunol.1100519. Epub 2011 Sep 26.

35.

Initial in vitro investigation of the human immune response to corneal cells from genetically engineered pigs.

Hara H, Koike N, Long C, Piluek J, Roh DS, SundarRaj N, Funderburgh JL, Mizuguchi Y, Isse K, Phelps CJ, Ball SF, Ayares DL, Cooper DK.

Invest Ophthalmol Vis Sci. 2011 Jul 15;52(8):5278-86. doi: 10.1167/iovs.10-6947.

36.

Hepatic B7 homolog 1 expression is essential for controlling cold ischemia/reperfusion injury after mouse liver transplantation.

Ueki S, Castellaneta A, Yoshida O, Ozaki K, Zhang M, Kimura S, Isse K, Ross M, Shao L, Stolz DB, Thomson AW, Demetris AJ, Geller DA, Murase N.

Hepatology. 2011 Jul;54(1):216-28. doi: 10.1002/hep.24360.

37.

Adding value to liver (and allograft) biopsy evaluation using a combination of multiplex quantum dot immunostaining, high-resolution whole-slide digital imaging, and automated image analysis.

Isse K, Grama K, Abbott IM, Lesniak A, Lunz JG, Lee WM, Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris AJ.

Clin Liver Dis. 2010 Nov;14(4):669-85. doi: 10.1016/j.cld.2010.07.004. Review.

PMID:
21055689
38.

Estrogen stimulates female biliary epithelial cell interleukin-6 expression in mice and humans.

Isse K, Specht SM, Lunz JG 3rd, Kang LI, Mizuguchi Y, Demetris AJ.

Hepatology. 2010 Mar;51(3):869-80. doi: 10.1002/hep.23386.

PMID:
20043322
39.

Histologic graft assessment after clinical islet transplantation.

Toso C, Isse K, Demetris AJ, Dinyari P, Koh A, Imes S, Kin T, Emamaullee J, Senior P, Shapiro AM.

Transplantation. 2009 Dec 15;88(11):1286-93. doi: 10.1097/TP.0b013e3181bc06b0.

PMID:
19996928
40.

Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis.

Harada K, Shimoda S, Sato Y, Isse K, Ikeda H, Nakanuma Y.

Clin Exp Immunol. 2009 Aug;157(2):261-70. doi: 10.1111/j.1365-2249.2009.03947.x.

41.

Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor.

Li G, Han C, Xu L, Lim K, Isse K, Wu T.

Hepatology. 2009 Sep;50(3):834-43. doi: 10.1002/hep.23052.

42.

Epithelial-mesenchymal transition induced by biliary innate immunity contributes to the sclerosing cholangiopathy of biliary atresia.

Harada K, Sato Y, Ikeda H, Isse K, Ozaki S, Enomae M, Ohama K, Katayanagi K, Kurumaya H, Matsui A, Nakanuma Y.

J Pathol. 2009 Apr;217(5):654-64. doi: 10.1002/path.2488.

PMID:
19116990
43.

Neuroradiologic evidence of pre-synaptic and post-synaptic nigrostriatal dopaminergic dysfunction in idiopathic Basal Ganglia calcification: a case report.

Saito T, Nakamura M, Shimizu T, Oda K, Ishiwata K, Ishii K, Isse K.

J Neuroimaging. 2010 Apr;20(2):189-91. doi: 10.1111/j.1552-6569.2008.00314.x. Epub 2008 Oct 21.

PMID:
19021829
44.

Tardive seizure and antibiotics: case reports and review of the literature.

Saito T, Nakamura M, Watari M, Isse K.

J ECT. 2008 Dec;24(4):275-6. doi: 10.1097/YCT.0b013e31816ba986.

PMID:
18580694
45.

Induction of innate immune response and absence of subsequent tolerance to dsRNA in biliary epithelial cells relate to the pathogenesis of biliary atresia.

Harada K, Sato Y, Isse K, Ikeda H, Nakanuma Y.

Liver Int. 2008 May;28(5):614-21. doi: 10.1111/j.1478-3231.2008.01740.x.

PMID:
18433391
46.
48.

Involvement of Escherichia coli in pathogenesis of xanthogranulomatous cholecystitis with scavenger receptor class A and CXCL16-CXCR6 interaction.

Sawada S, Harada K, Isse K, Sato Y, Sasaki M, Kaizaki Y, Nakanuma Y.

Pathol Int. 2007 Oct;57(10):652-63.

PMID:
17803654
49.

Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia.

Harada K, Sato Y, Itatsu K, Isse K, Ikeda H, Yasoshima M, Zen Y, Matsui A, Nakanuma Y.

Hepatology. 2007 Oct;46(4):1146-54.

PMID:
17661372
50.

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