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Items: 1 to 50 of 151

1.

MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.

Terunuma A, Putluri N, Mishra P, Mathé EA, Dorsey TH, Yi M, Wallace TA, Issaq HJ, Zhou M, Killian JK, Stevenson HS, Karoly ED, Chan K, Samanta S, Prieto D, Hsu TY, Kurley SJ, Putluri V, Sonavane R, Edelman DC, Wulff J, Starks AM, Yang Y, Kittles RA, Yfantis HG, Lee DH, Ioffe OB, Schiff R, Stephens RM, Meltzer PS, Veenstra TD, Westbrook TF, Sreekumar A, Ambs S.

J Clin Invest. 2014 Jan;124(1):398-412. doi: 10.1172/JCI71180. Epub 2013 Dec 9.

2.

Prospective evaluation of serum sarcosine and risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.

Koutros S, Meyer TE, Fox SD, Issaq HJ, Veenstra TD, Huang WY, Yu K, Albanes D, Chu LW, Andriole G, Hoover RN, Hsing AW, Berndt SI.

Carcinogenesis. 2013 Oct;34(10):2281-5. doi: 10.1093/carcin/bgt176. Epub 2013 May 22.

3.

Fractionation of peptides by strong cation-exchange liquid chromatography.

Chan KC, Issaq HJ.

Methods Mol Biol. 2013;1002:311-5. doi: 10.1007/978-1-62703-360-2_23.

PMID:
23625412
4.

Global proteomics and metabolomics in cancer biomarker discovery.

Issaq HJ, Fox SD, Chan KC, Veenstra TD.

J Sep Sci. 2011 Dec;34(24):3484-92. doi: 10.1002/jssc.201100528. Epub 2011 Nov 21. Review.

PMID:
22102289
5.

Is sarcosine a biomarker for prostate cancer?

Issaq HJ, Veenstra TD.

J Sep Sci. 2011 Dec;34(24):3619-21. doi: 10.1002/jssc.201100572. Epub 2011 Oct 19.

PMID:
22009695
6.

An Efficient Stochastic Search for Bayesian Variable Selection with High-Dimensional Correlated Predictors.

Kwon D, Landi MT, Vannucci M, Issaq HJ, Prieto D, Pfeiffer RM.

Comput Stat Data Anal. 2011 Oct 1;55(10):2807-2818.

7.

A reproducible and high-throughput HPLC/MS method to separate sarcosine from α- and β-alanine and to quantify sarcosine in human serum and urine.

Meyer TE, Fox SD, Issaq HJ, Xu X, Chu LW, Veenstra TD, Hsing AW.

Anal Chem. 2011 Jul 15;83(14):5735-40. doi: 10.1021/ac201003r. Epub 2011 Jun 21.

PMID:
21635006
8.

Proteomic biomarker discovery: it's more than just mass spectrometry.

Blonder J, Issaq HJ, Veenstra TD.

Electrophoresis. 2011 Jun;32(13):1541-8. doi: 10.1002/elps.201000585. Epub 2011 May 9. Review.

PMID:
21557261
9.

Quantitation of free and total bisphenol A in human urine using liquid chromatography-tandem mass spectrometry.

Fox SD, Falk RT, Veenstra TD, Issaq HJ.

J Sep Sci. 2011 Jun;34(11):1268-74. doi: 10.1002/jssc.201100087. Epub 2011 Apr 20.

PMID:
21506272
10.

Cancer biomarker discovery: Opportunities and pitfalls in analytical methods.

Issaq HJ, Waybright TJ, Veenstra TD.

Electrophoresis. 2011 Apr;32(9):967-75. doi: 10.1002/elps.201000588. Epub 2011 Mar 30. Review.

PMID:
21449066
11.

Comparison of fluorescence, laser-induced fluorescence, and ultraviolet absorbance detection for measuring HPLC fractionated protein/peptide mixtures.

Chan KC, Veenstra TD, Issaq HJ.

Anal Chem. 2011 Mar 15;83(6):2394-6. doi: 10.1021/ac1032462. Epub 2011 Feb 14.

PMID:
21319742
12.

Quantitation of nanoparticles in serum matrix by capillary electrophoresis.

Chan KC, Veenstra TD, Issaq HJ.

Methods Mol Biol. 2011;697:145-53. doi: 10.1007/978-1-60327-198-1_15.

PMID:
21116963
13.

Metabolic profiling for the detection of bladder cancer.

Van QN, Veenstra TD, Issaq HJ.

Curr Urol Rep. 2011 Feb;12(1):34-40. doi: 10.1007/s11934-010-0151-3.

PMID:
21061098
14.

Comparison of strong cation exchange and SDS-PAGE fractionation for analysis of multiprotein complexes.

Das S, Bosley AD, Ye X, Chan KC, Chu I, Green JE, Issaq HJ, Veenstra TD, Andresson T.

J Proteome Res. 2010 Dec 3;9(12):6696-704. doi: 10.1021/pr100843x. Epub 2010 Nov 9.

15.

Optimized method for computing (18)O/(16)O ratios of differentially stable-isotope labeled peptides in the context of postdigestion (18)O exchange/labeling.

Ye X, Luke BT, Johann DJ Jr, Ono A, Prieto DA, Chan KC, Issaq HJ, Veenstra TD, Blonder J.

Anal Chem. 2010 Jul 1;82(13):5878-86. doi: 10.1021/ac101284c.

16.

Combined blood/tissue analysis for cancer biomarker discovery: application to renal cell carcinoma.

Johann DJ Jr, Wei BR, Prieto DA, Chan KC, Ye X, Valera VA, Simpson RM, Rudnick PA, Xiao Z, Issaq HJ, Linehan WM, Stein SE, Veenstra TD, Blonder J.

Anal Chem. 2010 Mar 1;82(5):1584-8. doi: 10.1021/ac902204k.

17.

Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo.

Krakauer T, Buckley M, Issaq HJ, Fox SD.

Antimicrob Agents Chemother. 2010 Mar;54(3):1125-31. doi: 10.1128/AAC.01015-09. Epub 2010 Jan 19.

18.

Optimization of protein solubilization for the analysis of the CD14 human monocyte membrane proteome using LC-MS/MS.

Ye X, Johann DJ Jr, Hakami RM, Xiao Z, Meng Z, Ulrich RG, Issaq HJ, Veenstra TD, Blonder J.

J Proteomics. 2009 Nov 2;73(1):112-22. doi: 10.1016/j.jprot.2009.08.008. Epub 2009 Aug 24.

19.

Analytical and statistical approaches to metabolomics research.

Issaq HJ, Van QN, Waybright TJ, Muschik GM, Veenstra TD.

J Sep Sci. 2009 Jul;32(13):2183-99. doi: 10.1002/jssc.200900152. Review.

PMID:
19569098
20.

Separation, detection and quantitation of peptides by liquid chromatography and capillary electrochromatography.

Issaq HJ, Chan KC, Blonder J, Ye X, Veenstra TD.

J Chromatogr A. 2009 Mar 6;1216(10):1825-37. doi: 10.1016/j.chroma.2008.12.052. Epub 2008 Dec 25. Review.

PMID:
19131068
21.

Electrophoresis and liquid chromatography/tandem mass spectrometry in disease biomarker discovery.

Issaq HJ, Blonder J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 May 1;877(13):1222-8. doi: 10.1016/j.jchromb.2008.12.028. Epub 2008 Dec 24. Review.

PMID:
19117811
22.

Would you prefer multiple reaction monitoring or antibodies with your biomarker validation?

Issaq HJ, Veenstra TD.

Expert Rev Proteomics. 2008 Dec;5(6):761-3. doi: 10.1586/14789450.5.6.761. No abstract available.

PMID:
19086854
23.

CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients.

Read SW, Lempicki RA, Di Mascio M, Srinivasula S, Burke R, Sachau W, Bosche M, Adelsberger JW, Sereti I, Davey RT Jr, Tavel JA, Huang CY, Issaq HJ, Fox SD, Lane H, Kovacs JA.

J Infect Dis. 2008 Sep 15;198(6):843-50. doi: 10.1086/591250.

24.

Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid.

Xu X, Othman Eel-D, Issaq HJ, Hornung D, Al-Hendy A, Veenstra TD.

Electrophoresis. 2008 Jun;29(12):2706-13. doi: 10.1002/elps.200700837.

25.

Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry.

Issaq HJ, Nativ O, Waybright T, Luke B, Veenstra TD, Issaq EJ, Kravstov A, Mullerad M.

J Urol. 2008 Jun;179(6):2422-6. doi: 10.1016/j.juro.2008.01.084. Epub 2008 Apr 23.

PMID:
18433783
26.

Clinical and pharmaceutical applications of packed-column supercritical fluid chromatography.

Abbott E, Veenstra TD, Issaq HJ.

J Sep Sci. 2008 May;31(8):1223-30. doi: 10.1002/jssc.200700579. Review.

PMID:
18366028
27.

Utility of separation science in metabolomic studies.

Issaq HJ, Abbott E, Veenstra TD.

J Sep Sci. 2008 Jun;31(11):1936-47. doi: 10.1002/jssc.200700601. Review.

PMID:
18348322
28.

Comparison of 1D and 2D NMR spectroscopy for metabolic profiling.

Van QN, Issaq HJ, Jiang Q, Li Q, Muschik GM, Waybright TJ, Lou H, Dean M, Uitto J, Veenstra TD.

J Proteome Res. 2008 Feb;7(2):630-9.

PMID:
18081246
29.

Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD.

J Proteome Res. 2007 Nov;6(11):4150-62. Epub 2007 Oct 9.

PMID:
17924679
30.

Quantitative measurement of endogenous estrogens and estrogen metabolites in human serum by liquid chromatography-tandem mass spectrometry.

Xu X, Roman JM, Issaq HJ, Keefer LK, Veenstra TD, Ziegler RG.

Anal Chem. 2007 Oct 15;79(20):7813-21. Epub 2007 Sep 12.

PMID:
17848096
31.

Phosphoproteomics for the discovery of kinases as cancer biomarkers and drug targets.

Yu LR, Issaq HJ, Veenstra TD.

Proteomics Clin Appl. 2007 Sep;1(9):1042-57. doi: 10.1002/prca.200700102. Epub 2007 Aug 17.

PMID:
21136756
32.

Serum and plasma proteomics.

Issaq HJ, Xiao Z, Veenstra TD.

Chem Rev. 2007 Aug;107(8):3601-20. Epub 2007 Jul 18. Review. No abstract available.

PMID:
17636887
33.

The role of electrophoresis in disease biomarker discovery.

Issaq HJ, Veenstra TD.

Electrophoresis. 2007 Jun;28(12):1980-8. Review.

PMID:
17503404
34.

Analysis of fullerene-based nanomaterial in serum matrix by CE.

Chan KC, Patri AK, Veenstra TD, McNeil SE, Issaq HJ.

Electrophoresis. 2007 May;28(10):1518-24.

PMID:
17447247
36.

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

Granville CA, Warfel N, Tsurutani J, Hollander MC, Robertson M, Fox SD, Veenstra TD, Issaq HJ, Linnoila RI, Dennis PA.

Clin Cancer Res. 2007 Apr 1;13(7):2281-9.

37.

Quantitative proteomic analysis of human breast epithelial cells with differential telomere length.

Yu LR, Chan KC, Tahara H, Lucas DA, Chatterjee K, Issaq HJ, Veenstra TD.

Biochem Biophys Res Commun. 2007 May 18;356(4):942-7. Epub 2007 Mar 22.

38.

Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.

Xiao Z, Camalier CE, Nagashima K, Chan KC, Lucas DA, de la Cruz MJ, Gignac M, Lockett S, Issaq HJ, Veenstra TD, Conrads TP, Beck GR Jr.

J Cell Physiol. 2007 Feb;210(2):325-35.

PMID:
17096383
39.

Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma.

Stockwin LH, Blonder J, Bumke MA, Lucas DA, Chan KC, Conrads TP, Issaq HJ, Veenstra TD, Newton DL, Rybak SM.

J Proteome Res. 2006 Nov;5(11):2996-3007.

PMID:
17081051
40.

Identification of the SELDI ProteinChip human serum retentate by microcapillary liquid chromatography-tandem mass spectrometry.

Zhou M, Prieto DA, Lucas DA, Chan KC, Issaq HJ, Veenstra TD, Conrads TP.

J Proteome Res. 2006 Sep;5(9):2207-16.

PMID:
16944932
41.

Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications.

Yang H, Yu LR, Yi M, Lucas DA, Lukes L, Lancaster M, Chan KC, Issaq HJ, Stephens RM, Conrads TP, Veenstra TD, Hunter KW.

J Proteome Res. 2006 Jul;5(7):1555-67.

42.

Analysis of fifteen estrogen metabolites using packed column supercritical fluid chromatography-mass spectrometry.

Xu X, Roman JM, Veenstra TD, Van Anda J, Ziegler RG, Issaq HJ.

Anal Chem. 2006 Mar 1;78(5):1553-8.

PMID:
16503607
43.

Combined chemical and enzymatic stable isotope labeling for quantitative profiling of detergent-insoluble membrane proteins isolated using Triton X-100 and Brij-96.

Blonder J, Yu LR, Radeva G, Chan KC, Lucas DA, Waybright TJ, Issaq HJ, Sharom FJ, Veenstra TD.

J Proteome Res. 2006 Feb;5(2):349-60.

44.

Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry.

Xu X, Veenstra TD, Fox SD, Roman JM, Issaq HJ, Falk R, Saavedra JE, Keefer LK, Ziegler RG.

Anal Chem. 2005 Oct 15;77(20):6646-54.

PMID:
16223252
45.

Investigation of the mouse serum proteome.

Hood BL, Zhou M, Chan KC, Lucas DA, Kim GJ, Issaq HJ, Veenstra TD, Conrads TP.

J Proteome Res. 2005 Sep-Oct;4(5):1561-8.

PMID:
16212407
46.

Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients.

Kovacs JA, Lempicki RA, Sidorov IA, Adelsberger JW, Sereti I, Sachau W, Kelly G, Metcalf JA, Davey RT Jr, Falloon J, Polis MA, Tavel J, Stevens R, Lambert L, Hosack DA, Bosche M, Issaq HJ, Fox SD, Leitman S, Baseler MW, Masur H, Di Mascio M, Dimitrov DS, Lane HC.

J Clin Invest. 2005 Aug;115(8):2139-48. Epub 2005 Jul 14.

47.

Quantitative analysis of the low molecular weight serum proteome using 18O stable isotope labeling in a lung tumor xenograft mouse model.

Hood BL, Lucas DA, Kim G, Chan KC, Blonder J, Issaq HJ, Veenstra TD, Conrads TP, Pollet I, Karsan A.

J Am Soc Mass Spectrom. 2005 Aug;16(8):1221-30.

48.

Quantitative profiling of the detergent-resistant membrane proteome of iota-b toxin induced vero cells.

Blonder J, Hale ML, Chan KC, Yu LR, Lucas DA, Conrads TP, Zhou M, Popoff MR, Issaq HJ, Stiles BG, Veenstra TD.

J Proteome Res. 2005 Mar-Apr;4(2):523-31.

PMID:
15822930
49.
50.

Multidimensional separation of peptides for effective proteomic analysis.

Issaq HJ, Chan KC, Janini GM, Conrads TP, Veenstra TD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Mar 5;817(1):35-47. Review.

PMID:
15680787

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